AKIBAT HUKUM TERHADAP DEBITOR DAN KONSUMEN ATAS PAILITNYA PT. COWELL DEVELOPMENT Tbk ( Analisa Putusan Pengadilan Niaga di PN Jakarta Pusat Nomor : 21/Pdt-Sus-Pailit/2020/PN.Niaga.Jkt.Pst. Tanggal 02 Juli 2020 )

This study analyzes the decision of the judges of the commercial court in central Jakarta district cour No.21/Pdt-Sus-Pailit/2020/PN.Niaga.Jkt.Pst regarding the bankruptcy decision against PT. Cowell Development Tbk. The purpose of this research is to find out and analyze the legal consequence for debtors and consumers for the bankruptcy cases that occurred at PT. Cowell Development Tbk. the research method used in the research. This is a normative juridical or doctrinal legal research method (dogmatic). So that in addition to using the normative juridical research method, it also uses a historical research approach, added with a Law approach and a conceptual approach as a research method. In general the legal consequences that occur caused by are on the debtors property which will be confiscated by general, so that from the process of bankruptcy, in this case the most disadvantaged is the consumer because the majority of consumers have not received a Certificate of Ownership on land and only have a Sale and Purchase Binding Agreement and the position of consumers is very weak be cause  they are only creditors concurrent debtors whose positions are under the secessionist and preferred creditors to obtain compensation. that the judge’s consideration in his decision regarding the filing of the Bankruptcy Application is guided by Article 2 of low No. : 37 of 2004 based on the principles of fast, simple, and low-cost justice.Keywords : Bankruptcy, Debtor, Consumer, Verdict, Commercial court

Literature Review: Mathematical Creative Thinking Ability, and Students’ Self Regulated Learning to Use an Open Ended Approach

The ability to think creatively and self regulated learning is very important in learning mathematics, in order to train students to develop their creativity. But in reality, mathematics learning that is currently happening has not been able to develop mathematical creative thinking skills and increase students’ self-regulated learning. The purpose of this study is to examine the relationship between the open-ended approach and the ability to think creative mathematically and self-regulated learning and how to implement it in school in the perspective of literature review. The type of research used is literature review, where articles are collected using search engines such as EBSCO, Science direct, and Scopus. Based on the articles collected, the results show that: 1. Mathematics learning to use an open-ended approach has an effect on increasing students ‘creative thinking skills and self-regulated learning, 2. The open-ended approach is higher in increasing students’ creative thinking abilities compared to using a conventional approach, 3. The open-ended approach to learning has the following steps: a) the teacher organizes students in learning activities; b) the teacher exposes students to open problems; c) the teacher guides and directs students in solving problems with various solutions and various answers; d) students present their work and compare with the work of other students in front of the class; and e) students conclude the subject matter, which is guided by the teacher. 4. To apply open-ended learning, it is necessary to prepare learning that requires high creativity for a teacher

Follow Up of Maternally Derived Antibodies Titer against Economically Important Viral Diseases of Chicken

The study was conducted to know the rate of maternally derived antibodies (MDAs) transfer from parents to their offspring and declining the MDAs in their chicks at 0, 7, 14, and 21 days of age against four major poultry viruses like Newcastle disease virus (NDV), Infectious bronchitis virus (IBV), Infectious bursal diseases virus (IBDV), and Avian Reo virus (ARV). The MDAs was studied on Grandparent (GP) to Parent stock (PS), and Parent stock (PS) to broiler at 30 weeks and 50 weeks of age in Cobb-500 broiler strain chicken. The MDAs was measured from serum antibody titer by indirect ELISA test. The MDAs transfer rate against NDV from GP to PS at 50 weeks of age was higher (68.82%) than at 30 weeks of age but in case of PS to broiler it was higher (66.01%) at 30 weeks of age and its persistent rate also higher (7.96%) up to 21th days of age. Against IBV, MDAs transfer rates were higher in PS to broiler than GP to PS of both ages and highest rates were revealed in PS to broiler at 30 weeks of age as 70.72%. On the other hand, among all lines MDAs transfer rates against IBDV was higher (86.94%) in GP to PS at 30 weeks of age. For ARV, the MDAs transfer rates were highest in GP to PS in both ages than PS to broiler and within GP to PS at 50 weeks of age, it was highest (94.87%) than 30 weeks of age. Accordingly, the poultry producer may help to develop an effective vaccination schedule by considering the MDAs from above experiment

Improvement of potato based cropping patterns by inclusion of short duration Mungbean and T. Aman rice in Monga prone areas of Rangpur

The experiment was carried out to compare the improved cropping patterns against the farmers existing potato based cropping patterns having no mungbean/brown manure crop for higher yield, economic return and income generation in agricultural field in the off period following RCBD design with three replications at farmers field at Paikan Gangachara, Rangpur district during September- October. The treatments (cropping patterns) were T1 = T. aman rice (BINA 7) - Potato - Mungbean (BARI mungbean 6) (Improved pattern), T2 = T. aman rice (BR11) - Potato - Fallow (Farmers pattern), T3 = T. aman rice (BINA 7) - Potato + Maize intercrop - Mungbean (Improved pattern) and T4 = T. aman rice (BR11) - Potato / Maize relay (Farmers pattern). The highest yield (4.16 t ha-1) was recorded in T2 (BR11) which is statistically at par with T4 (4.15 t ha-1) but higher than the other treatments. Early planting sole potato (T1) gave highest yield (26.10 t ha-1) which was significantly higher than all other treatments. Late planting sole potato (T2), intercropped early potato (T3) and relay potato (T4) showed similar yield (23.61 24.79 t ha-1). Intercropped (T3) and Relay (T4) maize did not vary significantly in the studied parameters and yields were 8.21 and 7.92 t ha-1, respectively. Mungbean after sole potato (T1) gave higher number of pods/plant (17.25), and yield (1.47 t ha-1) which is significantly higher than those of T3 (14.89 and 1.28 t ha-1, respectively). Highest gross return (GR) (Tk. 417720) and gross margin (GM) (Tk. 220220) were calculated in improved pattern T3 and the lowest of those (Tk. 289670, Tk. 146020) in farmers pattern T2 . The other improved pattern T3 was the second highest performer considering GR and GM. But BCR (2.21) was highest in T1 and second highest in T3. The results indicated that the improved patterns (T1, T3) were better than farmers pattern (T2, T4). The improved pattern (T1) gave GR Tk. 67890 and GM Tk. 51785 higher than farmers pattern (T2). Similarly, the other improved pattern (T3) showed Tk. 51870 and Tk. 37395 higher than farmers pattern (T4). The improved pattern T1 and T3 created 45 working day job for the labour for harvesting early matured rice in the Monga/ jobless period (October) while farmers pattern gives only 3 days work. The mungbean included improved cropping patterns can be suggested for increased production, economic return and Monga mitigation (work opportunity in off period) in Rangpur. DOI: http://dx.doi.org/10.3329/ijarit.v4i2.22645 Int. J. Agril. Res. Innov. & Tech. 4 (2): 35-40, December, 201

Eco-friendly biosynthesis, anticancer drug loading and cytotoxic effect of capped ag-nanoparticles against breast cancer

© The Author(s) 2017. The work aimed to prepare silver nanoparticles (Ag-NPs) from silver nitrate and various concentrations of the seed extract (Setaria verticillata) by a green synthetic route. The chemical and physical properties of the resulting Ag-NPs were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectrometry and ultraviolet–visible (UV–Vis) spectrophotometry. Anticancer activity of Ag-NPs (5–20 nm) had dose-dependent cytotoxic effect against breast cancer (MCF7-FLV) cells. The in vitro toxicity was studied on adult earthworms (Lumbricina) resulting in statistically significant (P < 0.05) inhibition. The prepared NPs were loaded with hydrophilic anticancer drugs (ACD), doxorubicin (DOX) and daunorubicin (DNR), for developing a novel drug delivery carrier having significant adsorption capacity and efficiency to remove the side effects of the medicines effective for leukemia chemotherapy

Dealing naturally with stumbling blocks on highways and byways of TRAIL induced signaling.

In-depth analysis of how TRAIL signals through death receptors to induce apoptosis in cancer cells using high throughput technologies has added new layers of knowledge. However, the wealth of information has also highlighted the fact that TRAIL induced apoptosis may be impaired as evidenced by experimental findings obtained from TRAIL resistant cancer cell lines. Overwhelmingly, increasing understanding of TRAIL mediated apoptosis has helped in identifying synthetic and natural compounds which can restore TRAIL induced apoptosis via functionalization of either extrinsic or intrinsic pathways. Increasingly it is being realized that biologically active phytochemicals modulate TRAIL induced apoptosis, as evidenced by cell-based studies. In this review we have attempted to provide an overview of how different phytonutrients have shown efficacy in restoring apoptosis in TRAIL resistant cancer cells. We partition this review into how the TRAIL mediated signaling landscape has broadened over the years and how TRAIL induced signaling machinery crosstalks with autophagic protein networks. Subsequently, we provide a generalized view of considerable biological activity of coumarins against a wide range of cancer cell lines and how coumarins (psoralidin and esculetin) isolated from natural sources have improved TRAIL induced apoptosis in resistant cancer cells. We summarize recent updates on piperlongumine, phenethyl isothiocyanate and luteolin induced activation of TRAIL mediated apoptosis. The data obtained from pre-clinical studies will be helpful in translation of information from benchtop to the bedside

Prevalence and Correlates of Common Mental Disorders among Mothers of Young Children in Kilimanjaro Region of Tanzania.

Although poor maternal mental health is a major public health problem, with detrimental effects on the individual, her children and society, information on its correlates in low-income countries is sparse. This study investigates the prevalence of common mental disorders (CMD) among at-risk mothers, and explores its associations with sociodemographic factors. This population-based survey of mothers of children aged 0-36 months used the 14-item Shona Symptom Questionnaire (SSQ). Mothers whose response was "yes" to 8 or more items on the scale were defined as "at risk of CMD." Of the 1,922 mothers (15-48 years), 28.8% were at risk of CMD. Risk of CMD was associated with verbal abuse, physical abuse, a partner who did not help with the care of the child, being in a polygamous relationship, a partner with low levels of education, and a partner who smoked cigarettes. Cohabiting appeared to be protective. Taken together, our results indicate the significance of the quality of relations with one's partner in shaping maternal mental health. The high proportion of mothers who are at risk of CMD emphasizes the importance of developing evidence-based mental health programmes as part of the care package aimed at improving maternal well-being in Tanzania and other similar settings

Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite

Background: Tuberculosis (TB), is caused by the bacteria, Mycobacterium tuberculosis and its a threat to humans since centuries. Depending on the type of TB, its treatment can last for 6-24 months which is a major cause for patients non-compliance and treatment failure. Many adverse effects are associated with the currently available TB medicines, and there has been no new anti-tuberculosis drug on the market for more than 50 year, as the drug development is very lengthy and budget consuming process.Development of the biocompatible nano drug delivery systems with the ability to minimize the side effects of the drugs, protection of the drug from enzymatic degradation. And most importantly the drug delivery systems which can deliver the drug at target site would increase the therapeutic efficacy. Nanovehicles with their tendency to release the drug in a sustained manner would result in the bioavalibilty of the drugs in the body for a longer period of time and this would reduce the dosing frequency in drug administration. The biocompatible nanovehicles with the properties like sustained release of drug of the target site, protection of the drug from physio-chemical degradation, reduction in dosing frequency, and prolong bioavailability of drug in the body would result in the shortening of the treatment duration. All of these factors would improve the patient compliance with chemotherapy of TB.Result: An anti-tuberculosis drug, 4-amino salicylic acid (4-ASA) was successfully intercalated into the interlamellae of zinc layered hydroxide (ZLH) via direct reaction with zinc oxide suspension. The X-ray diffraction patterns and FTIR analyses indicate that the molecule was successfully intercalated into the ZLH interlayer space with an average basal spacing of 24 Å. Furthermore, TGA and DTG results show that the drug 4-ASA is stabilized in the interlayers by electrostatic interaction. The release of 4-ASA from the nanocomposite was found to be in a sustained manner. The nanocomposite treated with normal 3T3 cells shows it reduces cell viability in a dose- and time-dependent manner.Conclusions: Sustained release formulation of the nanocomposite, 4-ASA intercalated into zinc layered hydroxides, with its ease of preparation, sustained release of the active and less-toxic to the cell is a step forward for a more patient-friendly chemotherapy of Tuberculosis

A Review of Different Applications of Wireless Sensor Network (WSN) in Monitoring Rehabilitation

Parkinson’s disease is a neurodegenerative brain disorder that affects movement. The lack of dopamine in the brain cells causes patients have lesser ability to regulate movement and emotions as time goes on. There is no cure for this disease. Although drug therapies are successful for some patients, most of the patients usually develop motor complications. In this paper, we presented our work towards the comparison of several wireless sensor network (WSN) systems for monitoring Parkinson’s patients. The designs of each system are explored. The parts being considered to design a wireless sensor network and limitations are discussed. These findings helped us to suggest a possible wireless sensor network system to supervise Parkinson’s diseases patients for a more extended period of time

Studying the effect of shear stud distribution on the behavior of steel-reactive powder concrete composite beams using ABAQUS software

Using the ABAQUS software, this article presents a numerical investigation on the effects of various stud distributions on the behavior of composite beams. A total of 24 continuous 2-span composite beam samples with a span length of 1 m were examined (concrete slab at the top and steel I-section at the bottom). The concrete slab used is made of a reactive powder concrete with a compressive strength of 100.29 MPa. The total depth of each sample was 0.220 m. The samples were separated into four groups. The first group involved 6 specimens with shear connectors distributed into 2 rows with different distances (65, 85, 105, 150, 200, and 250 mm). The second group had the same spacing of shear connectors as the first group except that the shear connectors were distributed with one row along the longitudinal axis. The third group consisted of six specimens with single and double shear connectors distributed along the longitudinal axis. The fourth group included six specimens with one row of shear connectors arranged in a staggered distribution along the longitudinal axis. Results show that the optimum spacing was 105 mm in all groups and the deflection in group four fluctuated up and down due to the non-symmetrical distribution of the shear connectors