Health related quality of life in the female-headed households

Introduction: According to psychological research female-headed households have a lot of physical and mental problems because they experience more stress and anxiety than other women in general population. Aims of this study determine of quality of life and associated factors in Female-headed households under cover Welfare Organization of Ilam Province. Materials & Methods: In this descriptive analytical study, 787 Female-headed households under cover Welfare Organization of Ilam in urban and rural Ilam province participated. Systematic random sampling used to as a sampling method. A validated questionnaire (SF - 36) completed in a Six-month interval and the data were collected for analysis. Findings: From 787 Female-headed households contributing to the project, the numbers of subjects missing were 79 and 708 of subjects completed questionnaires (response rate 89.9). Mean ± SD age of participants was 53.3± 19.18. We found that having the chronic disease and life in rural area was associated with a worse health related quality of life (p

Angiogenic factors and the risk of preeclampsia: A systematic review and meta-analysis

Background: The etiological nature of preeclampsia is heterogeneous. The use of biomarkers indices in early pregnancy helps to have appropriate stratification of pregnancies into high- and low risk for the purpose of choosing timely interventions. Objective: The aim of this systematic review was to determine the pathogenic role of soluble soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) inthe prediction of preeclampsia in women. Materials and Methods: We performed a systematic search of the international databases including PubMed, Scopus, and Web of Science until August 2017. The quality of included studies was assessed using the Newcastle-Ottawa Scale. The primary outcome in this review was preeclampsia. The statistical heterogeneity was assessed using the X2 test and quantified by I2. Pooled effects size was obtained by random effects model. Subgroup  analyses were also carried out. Results: Totally, 284 records were identified in the initial search and 15 records were finally included in the meta-analysis. The pooled odds ratios (ORs) for the association between the high level of sFlt-1 and low level of PlGF and subsequent development of preeclampsia among women were 5.20 (95% CI: 1.24–9.16) and 2.53 (95% CI: 1.33–3.75), respectively. The mean difference for sFlt-1 and PlGF in women with preeclampsia compared to controls was 1.15 (95% CI: 0.43–1.86) and –0.94 (95% CI: –1.37–0.52),respectively. Conclusion: According to the results from this meta-analysis, increased levels of sFlt-1 and reduced levels of PlGF predict the subsequent development of preeclampsia. Key words: Angiogenic factors, Preeclampsia, sFLT-1, PlGF

Determination of Trace Amounts of Lead Using the Flotation-spectrophotometric method

The present study describes a simple and highly selective method for separation, preconcentration and spectrophotometric determination of extremely low concentrations of lead. It is based on flotation of a complex of Pb2+ ions and Alizarin yellow between aqueous and n-hexane interface at pH = 6. The proposed procedure is also applied for determination of lead in both tap water and prepared sea water samples. Beer’s Law was obeyed over the concentration range of 3.86 × 10−8 To 8.20 × 10−7 molL−1 (8–170 ngmL−1) with an apparent molar absorptivity of 1.33 × 106 molL−1 cm−1 for a 100 mL aliquot of the water sample. The detection limit (n = 10) was 8.7 × 10−9 molL−1 (1.0 ngmL−1) and the Relative standard deviation (R.S.D), (n = 10) for 7.2 × 10−7 molL−1 (150 ngmL−1) of Pb (II) was 4.36%. A notable advantage of the method is that the determination of Pb (II) is free from the interference of almost all cations and ions found in the environment and waste water samples. The determination of Pb (II) in tap and synthetic seawater samples was also carried out by the present method. The results were satisfactorily comparable so that the applicability of the proposed method was confirmed to the real samples

Procalcitonin and white blood cell count (WBC), erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) alterations in children with systemic inflammatory response syndrome before and after treatment

Systemic inflammatory response syndrome (SIRS) due to infection is an important cause of morbidity and  mortality in children. The present prospective observational study aimed to determine the correlation  between  procalcitonin (PCT) and white blood cell count (WBC), erythrocyte sedimentation rate (ESR) and  C-reactive protein (CRP) in toddlers before and after treatment. Moreover, 50 patients aged 1 to 36 months who were hospitalized at the Pediatrics Ward in Besat Hospital, Sanansaj city, Kurdistan province Western  Iran through a census sampling method were recruited. The complete blood count (CBC) was measured via  cell counter; ESR by the Westergren method, CRP via semi quantitative method and PCT via semi quantitative  immune-chromatography method. Pearson correlation coefficient was used to estimate correlation between  WBC, ESR, CRP and PCT before and after treatment of SIRS. The results obtained show correlation coefficients between PCT and CRP as well as between PCT and ESR in the first day of trial before treatment were  determined as ‘good’ and ‘moderate’, respectively. However, there was no significant correlation between PCT and WBC. No significant correlation was found between PCT and WBC count, ESR and CRP at the third day of  treatment. It was concluded that procalcitonin and CRP is the most favorable values for confirming SIRS  diagnosis in the onset of treatment. PCT can be considered as the marker of choice for following up purposes.Key words: Systemic inflammatory response syndrome (SIRS), procalcitonin, toddlers, treatment

Comparison of the effect of delivery type on the quality of life in women attending to health centers of Ilam and Aivan during 2013

زمینه و هدف: در دوره پس از زایمان برخی تغییرات جسمی، روحی و اجتماعی در مادر بوجود می آید که بر کیفیت زندگی مادران و خانواده هایشان تأثیر می گذارد. با توجه به اهمیت کیفیت زندگی و دوره بعد از زایمان و عوامل موثر بر کیفیت زندگی پس از زایمان، از جمله نوع زایمان، این مطالعه به منظور مقایسه کیفیت زندگی زنان با زایمان طبیعی و سزارین در هشت هفته بعد از زایمان انجام شد. روش بررسی: این مطالعه توصیفی - تحلیلی بر روی100 خانم 35-18 ساله مراجعه کننده به مراکز بهداشتی درمانی شهرهای ایلام و ایوان در سال 1392 که معیارهای ورود به مطالعه را داشتند انجام شد. کیفیت زندگی نمونه ها در 2 تا 8 هفته اول بعد از زایمان، با استفاده از ابزار کیفیت زندگی SF-36 ارزیابی و مورد بررسی و مقایسه قرار گرفت. یافته ها: نتایج نشان داد میانگین نمره حیطه جسمانی کیفیت زندگی در گروه زایمان با روش طبیعی 77/17 ± 60/76 و بالاتر از میانگین نمره گروه زایمان با روش سزارین (72/17 ± 10/54) بود. همچنین میانگین نمره حیطه روانی کیفیت زندگی در گروه زایمان با روش طبیعی 04/19 ± 60/67 بود که این میزان بالاتر از میانگین گروه زایمان با روش سزارین (71/15 ± 60/63) می باشد. آزمون تی تفاوت معنی داری را بین دو گروه در حیطه های جسمانی و روانی کیفیت زندگی نشان داد (

The factors influencing on knowledge, attitudes, and practices in women with breast cancer referring to health centers of Ilam in 2013

Background& Aims: The mortality rate for breast cancer is directly related to the stage of disease at diagnosis. The present study aimed to determine the influencing factors on knowledge, attitudes, and practices of women regarding breast cancer and its screening methods. Material & Methods: In a cross- sectional study, evaluated 383 women referring health centers of Ilam. Sampling was done in two stages. The inclusion criteria were included healthy women with least literate. Data was collected by a two part questionnaire including demographic characteristics and knowledge, attitudes and practices of women regarding breast cancer and its screening methods. Data were analyzed by chi-square and t-test in SPSS-16 software and a significance level of 0.05. Results: The Mean ± SD knowledge score was 22.43 ± 11.01. The Mean ± SD attitude and performance score were 29.08 ± 3.34 and 3.52 ± 1.66 respectively. There was a significant correlation between age, occupation and education with knowledge, attitude and practice of women about breast cancer and its screening methods (P 0.05). Conclusion: However, half of the participants had good knowledge about breast cancer and screening procedures, but also, all participants with good knowledge hadn’t good practice. Therefore, it is necessary further training to enhance awareness and more research to identifying barriers to women's performance

Serum anti-cyclic citrullinated peptide antibodies before and after treatment by disease-modifying anti-rheumatic drugs

BACKGROUND: Rheumatoid arthritis (RA) is the most common chronic disease involving joints. Anti-cyclic citrullinated peptide (anti-CCP) as a specific antibody is a reliable index to early diagnosis of RA. Disease-modifying anti-rheumatic drugs (DMARDs) can reduce progression of RA joint destruction. The present study aimed to investigate the effects of DMARDs in reducing serum anti-CCP. METHODS: A cross-sectional study was performed on 30 patients including 22 females and 8 males RA patients according to the American College of Rheumatology (ACR) classification criteria, who referred to the Rheumatology Clinic. Treatment with DMARD group started at the beginning of the study (May 2009). At 1st and 6th month of the study, clinical findings and disease activities were recorded and anti-CCP was measured. RESULTS: At the beginning and the end of the study, morning stiffness for more than 1 h and involvement of three areas were, 28 (93%) and 12 (40%), respectively. Indicators of disease severity in patients, the mean ± SD serum levels of erythrocyte sedimentation rate at the beginning and end, were 40.7 (30-59) mm/1 h and 13.4 (9-86) respectively. Anti-CCP at the beginning and end of the study was 141.83 (65.8-101.09) U/ml and 65.8 (62-92) U/ml respectively (P < 0.05). Disease Activity Score in 28 joints and rheumatoid factor positive and C-reactive protein positive were significantly different at the onset and at the end of the study (P < 0.05). CONCLUSION: Measurement of serum anti-CCP is a helpful index of treatment response and monitoring of treatment efficacy in patients with RA.

5-year survival rates based on the type of leukemia in Iran, a Meta-analysis

Background: According to epidemiological studies, leukemia is among the five most common cancers in Iran. Keeping efforts to estimate survival is critical to monitoring and improving patients’ quality of life with leukemia. The purpose of this study was to evaluate the 5-year survival rate of leukemia patients in Iran using meta-analysis method. Methods: This meta-analysis was carried out according to studies that adhere to inclusion and exclusion criteria during enrolment. The valid Iranian databases included: Medex, Magiran, SID, and Medlib, along with international data bases, namely, Scopus, Pubmed, and ISI were searched to find relevant articles. After determining the heterogeneity between studies, the random effects models were used to estimate pooled survival in leukemia patients. Results: In total, 18 studies involving 2517 participants were included in this meta-analysis. The pooled 5-year survival rate was 0.56 % (95% CI, 0.54 to 0.58). According to types AML and ALL, the 5-year survival rates in Iran were 35.0 % (95% CI: 32.0-38.0) and 57.0 % (95% CI: 54.0-60.0), respectively. Conclusion: Based on our findings, slightly less than 50% of leukemia deaths happened in the first 5 years after diagnosis, which is lower than the global average

5-year survival rates based on the type of leukemia in Iran, a Meta-analysis

Background: According to epidemiological studies, leukemia is among the five most common cancers in Iran. Keeping efforts to estimate survival is critical to monitoring and improving patients’ quality of life with leukemia. The purpose of this study was to evaluate the 5-year survival rate of leukemia patients in Iran using meta-analysis method. Methods: This meta-analysis was carried out according to studies that adhere to inclusion and exclusion criteria during enrolment. The valid Iranian databases included: Medex, Magiran, SID, and Medlib, along with international data bases, namely, Scopus, Pubmed, and ISI were searched to find relevant articles. After determining the heterogeneity between studies, the random effects models were used to estimate pooled survival in leukemia patients. Results: In total, 18 studies involving 2517 participants were included in this meta-analysis. The pooled 5-year survival rate was 0.56 % (95% CI, 0.54 to 0.58). According to types AML and ALL, the 5-year survival rates in Iran were 35.0 % (95% CI: 32.0-38.0) and 57.0 % (95% CI: 54.0-60.0), respectively. Conclusion: Based on our findings, slightly less than 50% of leukemia deaths happened in the first 5 years after diagnosis, which is lower than the global averag