539 research outputs found
Corrigendum to “The Effect of PEI and PVP-Stabilized Gold Nanoparticles on Equine Platelets Activation: Potential Application in Equine Regenerative Medicine”
Differences in the prognosis of HPV16-positive patients with squamous cell carcinoma of head and neck according to viral load and expression of P16
Purpose To evaluate the impact of HPV16 load (VL-the
number of virus genome copies per cell) and P16 expression
on prognosis of patients with squamous cell carcinomas
(SCCs) of head and neck (HN).
Materials and methods HPV16 presence was assessed in
the group of 109 patients with HNSCCs by quantitative polymerase
chain reaction (qPCR). VL (assessed by qPCR) and
P16 expression (evaluated by immunohistochemistry) were
analysed only in the subgroup of HPV16-positive tumours.
These features were correlated with 5-year overall survival
(OS) and disease-free survival (DFS).
Results HPV16 infection was found in 36 tumours
(33.0%). Virus-positive patients had better OS and DFS
than those without infection (P = 0.041 and 0.005). Among
HPV16-positive HNSCCs, 18 (50.0%) had higher VL
(median value > 6764.3 copies/cell) and 25 (73.5%) P16 over expression. The significant differences in OS and
DFS (P = 0.008 and 0.004) were noticed according to VL,
wherein 100% DFS was found for patients with higher
VL. According to P16 expression, significant difference
was found only for OS (P = 0.020). In multivariate analysis,
VL (P = 0.045; HR = 2.795; CI 0.121-1.060) and the
level of smoking (P = 0.023, HR = 2.253; CI 1.124-4.514)
were independent factors affecting DFS of HPV16-positive
patients.
Conclusion On the basis of viral load, it is possible to
differentiate prognosis of patients with HPV16-positive
HNSCCs. In this subgroup, viral load has stronger prognostic
potential than P16 expression
Role of the kidneys in the redistribution of heme-derived iron during neonatal hemolysis in mice
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Księga poświęcona Profesorowi Hieronimowi Kubiakowi w 75. rocznicę urodzin.
Tom ofiarowany przez przyjaciół i uczniów
Multidifferential study of identified charged hadron distributions in -tagged jets in proton-proton collisions at 13 TeV
Jet fragmentation functions are measured for the first time in proton-proton
collisions for charged pions, kaons, and protons within jets recoiling against
a boson. The charged-hadron distributions are studied longitudinally and
transversely to the jet direction for jets with transverse momentum 20 GeV and in the pseudorapidity range . The
data sample was collected with the LHCb experiment at a center-of-mass energy
of 13 TeV, corresponding to an integrated luminosity of 1.64 fb. Triple
differential distributions as a function of the hadron longitudinal momentum
fraction, hadron transverse momentum, and jet transverse momentum are also
measured for the first time. This helps constrain transverse-momentum-dependent
fragmentation functions. Differences in the shapes and magnitudes of the
measured distributions for the different hadron species provide insights into
the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb
public pages
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of the ratios of branching fractions and
The ratios of branching fractions
and are measured, assuming isospin symmetry, using a
sample of proton-proton collision data corresponding to 3.0 fb of
integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The
tau lepton is identified in the decay mode
. The measured values are
and
, where the first uncertainty is
statistical and the second is systematic. The correlation between these
measurements is . Results are consistent with the current average
of these quantities and are at a combined 1.9 standard deviations from the
predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb
public pages
Glosses for ontological aspects of radio-play
The article focuses on inaccuracy of terms which has appeared in the radio drama literature.
According to propounded thesis, original radio drama is a kind of adaptation, because its existence
in proper auditory form always requires a specific intersemiotic translation which involves at least acoustic scenario fruition. The thesis was verified on the material of Drugi pokój – Zbigniew
Herbert’s radio-play directed by Waldemar Modestowicz. Terms ‘original radio drama’ and
‘radio-play adaptation’ have the same basis, which demands analysis of radio drama’s features.
‘Subject’ and ‘recipient’ of an audio work focus on issues of perception, which is a starting point
for deliberation
The analysis of Mexican Spanish based on some Televisa’s telenovelas
Celem niniejszej pracy jest wyjaśnienie kilku kluczowych różnic między językiem kastylijskim a jego meksykańską odmianą. Ponadto, na podstawie czterech wybranych telenowel zaprezentowano, jak ważną rolę w każdej z tych produkcji pełnią meksykanizmy oraz jak ich obecność wpływa na zróżnicowanie słownictwa. Część teoretyczna pracy została poświęcona na wyjaśnienie, czym jest telenowela, między innymi, poprzez wskazanie jej charakterystycznych cech. Niemniej jednak, jej głównym zamierzeniem było obalenie dosyć powszechnego przekonania o tym, że telenowela jest synonimem opery mydlanej.The aim of this thesis is to demonstrate some of the most important differences with respect to Castilian and Mexican Spanish. Moreover, in our analysis, based on four chosen telenovelas, we would like to indicate the importance of mexicanisms in each of these productions and the variety of vocabulary created by them. However, the thesis focuses also on explaining what a telenovela is by presenting, among others, some characteristic features of this genre. Most of all, it proves that telenovela is not a synonym for the soap opera.El objetivo principal de esta memoria consiste en indicar algunas diferencias más importantes en cuanto al castellano y el español de México. Además, a través de cuatro telenovelas elegidas se muestra la gran importancia de mexicanismos en cada una de las producciones y la diversidad de vocabulario construida con base en ellos. No obstante, el trabajo se concentra también en explicar qué es una telenovela, entre otros, indica sus rasgos más característicos pero, sobre todo, refuta la convicción bastante común de que la telenovela es uno de los sinónimos de soap opera
Translator in Wonderland
Celem niniejszej pracy jest omówienie charakterystycznych cech literatury dziecięcej oraz kluczowych aspektów związanych z jej tłumaczeniem. Ponadto, wytłumaczona została perspektywa dziecka oraz jego oczekiwania wobec książki. Na postawie dzieła Lewisa Carrolla Alice’s Adventures in Wonderland pokazano, dlaczego humor w literaturze dziecięcej jest tak istotny oraz omówiono język, którym powieść została napisana. Następnie, dokonano analizy treści, aby móc jednoznacznie wskazać prawdziwego odbiorcę książki. Na koniec, została omówiona rola ilustracji w książkach dla dzieci. To doświadczenie ukazało nam różnorakie przedstawienia Alicji oraz udowodniło, że każda z nich jest wyjątkowa na swój sposób.The aim of this thesis is to demonstrate the main features of children’s literature. Thus, we comment on different aspects connected with the theory of translation of children’s literature. First of all, we explain a child´s perspective and their expectations as a reader. Then, based on Alice´s Adventures in Wonderland by Lewis Carroll we underline the importance of the humour in books for children and we comment on the language that is used therein. Moreover, we comment on the contents of this book to indicate its real reader. Finally, we comment on the role of illustration in children´s literature to show numerous faces of Alice.El presente trabajo tiene como objetivo demostrar las características principales de la literatura infantil. De ahí, se comentan diferentes aspectos relacionados con la teoría de la traducción de la literatura infantil. Primero, se explica la perspectiva de un niño y sus expectativas como lector. Luego, con base en la obra Alice´s Adventures in Wonderland de Lewis Carroll se subraya la importancia de comicidad en los libros destinados a los niños y se comenta el lenguaje que se utiliza. Además, se analiza el contenido de la obra para indicar su verdadero destinatario. Finalmente, se comenta el rol de la imagen en la literatura infantil para demostrar los múltiples rostros de Alicia
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