Aprendizajes y significados del uso de las computadoras y la Internet por parte de los actores (director, docente, alumno y padre de familia) en 2 instituciones educativas (II.EE.) de gesti?n p?blica en el distrito de Los Olivos, entre los meses de julio a setiembre del a?o 2010

El objetivo de esta investigaci?n fue explorar el aprendizaje y el significado que ha surgido en cada uno de los actores (director, docente, alumnos y padres de familia) como consecuencia del uso de las computadoras y la Internet al interior de dos instituciones educativas que pertenecieron a la etapa b?sica de la modalidad regular, del nivel primario y secundario, con poli docencia completa, de un sistema educativo p?blico, urbano, ubicado en el distrito de Los Olivos, en la zona norte de la ciudad de Lima, entre Julio a Septiembre de 2010

Epigenetics and lifestyle

The concept of 'lifestyle' includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression. It has been identified that several lifestyle factors such as diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants, psychological stress and working on night shifts might modify epigenetic patterns. Most of the studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle factors in relation to histone modifications and miRNAs. This article reviews current evidence indicating that lifestyle factors might affect human health via epigenetic mechanisms

Plan de negocios para la implementaci?n de un fast food de hamburguesas basada en vegetales

Hoy en d?a el consumidor es m?s consciente del cuidado de su salud y el medio ambiente esto involucra buscar m?s informaci?n sobre los productos y muchos restaurantes ahora han ampliado su oferta hacia lo saludable. Es por ello, el siguiente plan de negocio consiste en ofrecer una propuesta de fast food de hamburguesas basada en vegetales que ofrece al consumidor en Lima Moderna una opci?n diferente, una alternativa m?s saludable, sustentable con el medio ambiente a un precio conforme al mercado, favoreciendo la salud y satisfacer las necesidades del consumidor. El presente plan de negocios consta de 13 cap?tulos donde se desarrolla la propuesta de valor, la investigaci?n de mercado empleando entrevistas a expertos y encuestas con el prop?sito de determinar el mercado objetivo y validar la propuesta de valor. Luego de ello se defini? las estrategias a seguir para la implementaci?n del negocio, as? como definir los factores claves de ?xitos y concluyendo el desarrollo de los planes comercial, operaciones, recursos humanos, finanzas y riesgos. Con ello buscando determinar la viabilidad comercial, operativa y econ?mica del proyecto

A proposed methodology for establishing software process development improvement for small software development firms

Small software development firms represent the majority of all software firms in most countries. These firms are facing the same software engineering challenges that affect large software firms.Software Process Improvement (SPI) traditional models were developed to help large and very large firms, however small software firms could not afford these models. Furthermore, they need to manage and improve their software development processes for several reasons such as dealing with the rapid technology advances, maintaining their products, satisfying the customers’ needs and sustaining their operations. This paper presents the methodology’s stages of developing a suitable software development process improvement framework by using Capability Maturity Model Integration (CMMI-DEV V1.2) as the basic model for improvement and Extreme Programming (XP) method as the basic software development method

The genome of Bifidobacterium pseudocatenulatum IPLA 36007, a human intestinal strain with isoflavone-activation activity

Background: Bifidobacterium species, including Bifidobacterium pseudocatenulatum, are among the dominant microbial populations of the human gastrointestinal tract. They are also major components of many commercial probiotic products. Resident and transient bifidobacteria are thought to have several beneficial health effects. However, our knowledge of how these bacteria interact and communicate with host cells remains poor. This knowledge is essential for scientific support of their purported health benefits and their rational inclusion in functional foods. Results: This work describes the draft genome sequence of Bifidobacterium pseudocatenulatum IPLA 36007, a strain isolated as dominant from the feces of a healthy human. Besides several properties of probiosis, IPLA 36007 exhibited the capability of releasing aglycones from soy isoflavone glycosides. The genome contains 1,851 predicted genes, including 54 genes for tRNAs and fie copies of unique 16S, 23S and 5S rRNA genes. As key attributes of the IPLA 36007 genome we can mention the presence of a lysogenic phage, a cluster encoding type IV fimbriae, and a locus encoding a clustered, regularly interspaced, short, palindromic repeat (CRISPR)-Cas system. Four open reading frames (orfs) encoding \u3b2-glucosidases belonging to the glycosyl hydrolase family 3, which may act on isoflavone glycosides, were encountered. Additionally, one gene was found to code for a glycosyl hydrolase of family 1 that might also have \u3b2-glucosidase activity. Conclusion: The availability of the B. pseudocatenulatum IPLA 36007 genome should allow the enzyme system involved in the release of soy isoflavone aglycones from isoflavone glycosides, and the molecular mechanisms underlying the strain's probiotic properties, to be more easily understood

Plan de negocio basado en E-Health para el monitoreo de pacientes diagnosticados con hipertensi?n arterial en Lima Metropolitana

La prevalencia de enfermedades cr?nicas tales como la Hipertensi?n Arterial Alta es uno de los principales retos a los que se enfrenta el sistema de salud, entre ellos la elevada tasa de mortandad y el costo de su tratamiento, teniendo que destinar gran presupuesto a la atenci?n de estos pacientes. Ante ello nace una nueva tendencia conocida como eHealth la cual hace uso de las tecnolog?as de informaci?n aplicadas a la atenci?n m?dica. El presente modelo de negocio ?QualityHealth? constituye una experiencia pionera en Per? dentro del sector salud que ofrece el telemonitoreo a trav?s de dispositivos wearables, permitiendo el constante monitoreo y apoyo a distancia a pacientes hipertensos. QualityHealth busca mejorar la adherencia al tratamiento del paciente hipertenso con el prop?sito de evitar complicaciones que deterioren su salud y generar ahorros tanto al paciente como al sistema de salud a trav?s del: telemonitoreo y teleconsulta en cualquier momento y lugar a trav?s de IoT; foros especializados; bot?n de p?nico que contactar? de manera inmediata al grupo de apoyo del paciente en el caso de que su presi?n arterial supere los umbrales; historial de la presi?n arterial que permitir? realizar un an?lisis preventivo con ayuda de Machine Learning, alertas y recordatorios del tratamiento entre otros

Occupation-Related Differences in the Prevalence of Metabolic Syndrome

OBJECTIVE—To investigate the prevalence of metabolic syndrome in the Spanish working population and determine how the prevalence varies according to occupation and sex

Collaboration between centres of the World Health Organization : Italy supports a Mexican university

BACKGROUND: Mexico is the third most populous country in America. A sizeable percentage of Mexicans live under unfavorable conditions such as malnutrition, marginalization and overcrowding. Environmental injustice includes: indigenous exposed to wood smoke, families living in mining zones, children working and living in garbage dumps and brick factories. Polycyclic aromatic hydrocarbons, pesticides, electronic waste and heavy metals exposure represent a health risk. These pollutants can induce biochemical lesions as DNA damage and epigenetic changes which could modif the gene expression profile of each individual. OBJECTIVES: The aim of this work is to create an Italy-Mexico collaboration (within the context of WHO collaborating centres) between the Center of Molecular and Genetic Epidemiology, University of Milan and the University of San Luis Potosi, will allow molecular approaches to develop early indicators of susceptibility to adult disease and cancer

A new synonym for Eragrostis pilgeri (Poaceae: Eragrostideae)

Volume: 19Start Page: 1157End Page: 116