X-ray characterization of BUSARD chip: A HV-SOI monolithic particle detector with pixel sensors under the buried oxide

This work presents the design of BUSARD, an application specific integrated circuit (ASIC) for the detection of ionizing particles. The ASIC is a monolithic active pixel sensor which has been fabricated in a High-Voltage Silicon-On-Insulator (HV-SOI) process that allows the fabrication of a buried N+ diffusion below the Buried OXide (BOX) as a standard processing step. The first version of the chip, BUSARD-A, takes advantage of this buried diffusion as an ionizing particle sensor. It includes a small array of 13×13 pixels, with a pitch of 80 μm, and each pixel has one buried diffusion with a charge amplifier, discriminator with offset tuning and digital processing. The detector has several operation modes including particle counting and Time-over-Threshold (ToT). An initial X-ray characterization of the detector was carried out, obtaining several pulse height and ToT spectra, which then were used to perform the energy calibration of the device. The Molybdenum $_{α}$ emission was measured with a standard deviation of 127 e$^{-}$ of ENC by using the analog pulse output, and with 276 e$^{-}$ of ENC by using the ToT digital output. The resolution in ToT mode is dominated by the pixel-to-pixel variation

The exchange-stable marriage problem

In this paper we consider instances of stable matching problems, namely the classical stable marriage (SM) and stable roommates (SR) problems and their variants. In such instances we consider a stability criterion that has recently been proposed, that of <i>exchange-stability</i>. In particular, we prove that ESM — the problem of deciding, given an SM instance, whether an exchange-stable matching exists — is NP-complete. This result is in marked contrast with Gale and Shapley's classical linear-time algorithm for finding a stable matching in an instance of SM. We also extend the result for ESM to the SR case. Finally, we study some variants of ESM under weaker forms of exchange-stability, presenting both polynomial-time solvability and NP-completeness results for the corresponding existence questions

Cell biophysical stimuli in lobodopodium formation: a computer based approach

Different cell migration modes have been identified in 3D environments, e.g., modes incorporating lamellopodia or blebs. Recently, a new type of cellular migration has been investigated: lobopodia-based migration, which appears only in three-dimensional matrices under certain conditions. The cell creates a protrusion through which the nucleus slips, dividing the cell into two parts (front and rear) with different hydrostatic pressures. In this work, we elucidate the mechanical conditions that favour this type of migration. One of the hypotheses about this type of migration is that it depends on the mechanical properties of the extracellular matrix. That is, lobopodia-based migration is dependent on whether the extracellular matrix is linearly elastic or non-linearly elastic. To determine whether the mechanical properties of the extracellular matrix are crucial in the choice of cell migration mode and which mechanotransduction mechanism the cell might use, we develop a finite element model. From our simulations, we identify two different possible mechanotransduction mechanisms that could regulate the cell to switch from a lobopodial to a lamellipodial migration mode. The first relies on a differential pressure increase inside the cytoplasm while the cell contracts, and the second relies on a change in the fluid flow direction in non-linearly elastic extracellular matrices but not in linearly elastic matrices. The biphasic nature of the cell has been determined to mediate this mechanism and the different behaviours of cells in linearly elastic and non-linearly elastic matrices

Finite Element Simulation of the Deformation of a Cell Driven by Creeping Flow

The purpose of this work is to calculate the deformation undergone by a cell in function of its nucleus size and mechanical properties. The cell immersed in a fluid go through a variable section channel and it is deformed by fluid forces.Cell deformation into the channel causes changes at the fluid velocity profile. This fluid configuration change results in diferent normal and viscous forces around the cell. Due to strong correlation between cell deformation and fluid velocity profile, a fluidsolid interacción (FSI) is required

Virtual Processes and Superradiance in Spin-Boson Models

We consider spin-boson models composed by a single bosonic mode and an ensemble of $N$ identical two-level atoms. The situation where the coupling between the bosonic mode and the atoms generates real and virtual processes is studied, where the whole system is in thermal equilibrium with a reservoir at temperature $\beta^{-1}$. Phase transitions from ordinary fluorescence to superradiant phase in three different models is investigated. First a model where the coupling between the bosonic mode and the $j-th$ atom is via the pseudo-spin operator $\sigma^{,z}_{(j)}$ is studied. Second, we investigate the generalized Dicke model, introducing different coupling constants between the single mode bosonic field and the environment, $g_{1}$ and $g_{2}$ for rotating and counter-rotating terms, respectively. Finally it is considered a modified version of the generalized Dicke model with intensity-dependent coupling in the rotating terms. In the first model the zero mode contributes to render the canonical entropy a negative quantity for low temperatures. The last two models presents phase transitions, even when only Hamiltonian terms which generates virtual processes are considered

Using quantum state protection via dissipation in a quantum-dot molecule to solve the Deutsch problem

The wide set of control parameters and reduced size scale make semiconductor quantum dots attractive candidates to implement solid-state quantum computation. Considering an asymmetric double quantum dot coupled by tunneling, we combine the action of a laser field and the spontaneous emission of the excitonic state to protect an arbitrary superposition state of the indirect exciton and ground state. As a by-product we show how to use the protected state to solve the Deutsch problem.Comment: 8 pages, 1 figure, 2 table