824 research outputs found
The controversy in the process: potential scattering or resonance ?
The reaction shows a broad peak at 1.5
GeV in the channel which has no counterpart in the
channel. This "resonance" is considered as a candidate for a
state in the "s-channel". We show, however, that it can also
be explained by potential scattering of via the -
exchange in the "t-channel".Comment: 12 pages, latex, 3 postscript figures, to appear in Zeitschrift fur
Physi
Motor Fatigue Measurement by Distance-Induced Slow Down of Walking Speed in Multiple Sclerosis
Background: Motor fatigue and ambulation impairment are prominent clinical features of
people with multiple sclerosis (pMS). We hypothesized that a multimodal and comparative
assessment of walking speed on short and long distance would allow a better delineation and
quantification of gait fatigability in pMS.
Objectives: To compare 4 walking paradigms: the timed 25-foot walk (T25FW), a corrected
version of the T25FW with dynamic start (T25FW+), the timed 100-meter walk (T100MW)
and the timed 500-meter walk (T500MW).
Methods: Thirty controls and 81 pMS performed the 4 walking tests in a single study visit.
Results: The 4 walking tests were performed with a slower WS in pMS compared to controls
even in subgroups with minimal disability. The finishing speed of the last 100-meter of the
T500MW was the slowest measurable WS whereas the T25FW+ provided the fastest
measurable WS. The ratio between such slowest and fastest WS (Deceleration Index, DI) was
significantly lower only in pMS with EDSS 4.0-6.0, a pyramidal or cerebellar functional
system score reaching 3 or a maximum reported walking distance !4000m.
Conclusion: The motor fatigue which triggers gait deceleration over a sustained effort in pMS
can be measured by the WS ratio between performances on a very short distance and the
finishing pace on a longer more demanding task. The absolute walking speed is abnormal
early in MS whatever the distance of effort when patients are unaware of ambulation
impairment. In contrast, the DI-measured ambulation fatigability appears to take place later in the disease course
Reducing Constraints in a Higher Dimensional Extension of the Randall and Sundrum Model
In order to investigate the phenomenological implications of warped spaces in
more than five dimensions, we consider a dimensional extension to
the Randall and Sundrum model in which the space is warped with respect to a
single direction by the presence of an anisotropic bulk cosmological constant.
The Einstein equations are solved, giving rise to a range of possible spaces in
which the additional spaces are warped. Here we consider models in
which the gauge fields are free to propagate into such spaces. After carrying
out the Kaluza Klein (KK) decomposition of such fields it is found that the KK
mass spectrum changes significantly depending on how the additional
dimensions are warped. We proceed to compute the lower bound on the KK mass
scale from electroweak observables for models with a bulk
gauge symmetry and models with a bulk gauge
symmetry. It is found that in both cases the most favourable bounds are
approximately TeV, corresponding to a mass of the first gauge
boson excitation of about 4-6 TeV. Hence additional warped dimensions offer a
new way of reducing the constraints on the KK scale.Comment: 27 pages, 15 figures, v3: Additional comments in sections 1, 2 and 4.
New appendix added. Five additional figures. References adde
D3-brane Potentials from Fluxes in AdS/CFT
We give a comprehensive treatment of the scalar potential for a D3-brane in a
warped conifold region of a compactification with stabilized moduli. By
studying general ultraviolet perturbations in supergravity, we systematically
incorporate `compactification effects' sourced by supersymmetry breaking in the
compact space. Significant contributions to the D3-brane potential, including
the leading term in the infrared, arise from imaginary anti-self-dual (IASD)
fluxes. For an arbitrary Calabi-Yau cone, we determine the most general IASD
fluxes in terms of scalar harmonics, then compute the resulting D3-brane
potential. Specializing to the conifold, we identify the operator dual to each
mode of flux, and for chiral operators we confirm that the potential computed
in the gauge theory matches the gravity result. The effects of four-dimensional
curvature, including the leading D3-brane mass term, arise directly from the
ten-dimensional equations of motion. Furthermore, we show that gaugino
condensation on D7-branes provides a local source for IASD flux. This flux
precisely encodes the nonperturbative contributions to the D3-brane potential,
yielding a promising ten-dimensional representation of four-dimensional
nonperturbative effects. Our result encompasses all significant contributions
to the D3-brane potential discussed in the literature, and does so in the
single coherent framework of ten-dimensional supergravity. Moreover, we
identify new terms with irrational scaling dimensions that were inaccessible in
prior works. By decoupling gravity in a noncompact configuration, then
systematically reincorporating compactification effects as ultraviolet
perturbations, we have provided an approach in which Planck-suppressed
contributions to the D3-brane effective action can be computed.Comment: 70 page
The Custodial Randall-Sundrum Model: From Precision Tests to Higgs Physics
We reexamine the Randall-Sundrum (RS) model with enlarged gauge symmetry
SU(2)_L x SU(2)_R x U(1)_X x P_LR in the presence of a brane-localized Higgs
sector. In contrast to the existing literature, we perform the Kaluza-Klein
(KK) decomposition within the mass basis, which avoids the truncation of the KK
towers. Expanding the low-energy spectrum as well as the gauge couplings in
powers of the Higgs vacuum expectation value, we obtain analytic formulas which
allow for a deep understanding of the model-specific protection mechanisms of
the T parameter and the left-handed Z-boson couplings. In particular, in the
latter case we explain which contributions escape protection and identify them
with the irreducible sources of P_LR symmetry breaking. We furthermore show
explicitly that no protection mechanism is present in the charged-current
sector confirming existing model-independent findings. The main focus of the
phenomenological part of our work is a detailed discussion of Higgs-boson
couplings and their impact on physics at the CERN Large Hadron Collider. For
the first time, a complete one-loop calculation of all relevant Higgs-boson
production and decay channels is presented, incorporating the effects stemming
from the extended electroweak gauge-boson and fermion sectors.Comment: 74 pages, 13 figures, 3 tables. v2: Matches version published in JHE
Fluids in cosmology
We review the role of fluids in cosmology by first introducing them in
General Relativity and then by applying them to a FRW Universe's model. We
describe how relativistic and non-relativistic components evolve in the
background dynamics. We also introduce scalar fields to show that they are able
to yield an inflationary dynamics at very early times (inflation) and late
times (quintessence). Then, we proceed to study the thermodynamical properties
of the fluids and, lastly, its perturbed kinematics. We make emphasis in the
constrictions of parameters by recent cosmological probes.Comment: 34 pages, 4 figures, version accepted as invited review to the book
"Computational and Experimental Fluid Mechanics with Applications to Physics,
Engineering and the Environment". Version 2: typos corrected and references
expande
Pregnancy and Maternal Behavior Induce Changes in Glia, Glutamate and Its Metabolism within the Cingulate Cortex
An upregulation of the astrocytic proteins GFAP and bFGF within area 2 of the cingulate cortex (Cg2) occurs within 3 hours of parturition in rats. These changes are the result of an interaction between hormonal state and maternal experience and are associated with increased dendritic spine density in this area. Here, we examined whether this upregulation of astrocytic proteins generalized to other glial markers and, in particular those associated with glutamate metabolism. We chose glial markers commonly used to reflect different aspects of glial function: vimentin, like GFAP, is a marker of intermediate filaments; glutamine synthetase (GS), and S-100beta, are used as markers for mature astrocytes and GS has also been used as a specific marker for glutamatergic enzymatic activity. In addition, we examined levels of proteins associated with glutamine synthetase, glutamate, glutamine and two excitatory amino acid transporters found in astrocytes, glt-1 and glast. S100beta immunoreactivity did not vary with reproductive state in either Cg2 or MPOA suggesting no change in the number of mature astrocytes across these conditions. Vimentin-ir did not differ across groups in Cg2, but expression of this protein decreased from Day 1 postpartum onwards in the MPOA. By contrast, GS-ir was increased within 24 h postpartum in Cg2 but not MPOA and similarly to GFAP and bFGF this upregulation of GS resulted from an interaction between hormonal state and maternal experience. Within Cg2, upregulation of GS was not accompanied by changes in the astrocytic glutamatergic transporters, glt-1 and glast, however, an increase in both glutamate and glutamine proteins were observed within the Cg2 of postpartum animals. Together, these changes suggest postpartum upregulation of glutamatergic activity and metabolism within Cg2 that is stimulated by pregnancy hormones and maternal experience
Microwave studies of the fractional Josephson effect in HgTe-based Josephson junctions
The rise of topological phases of matter is strongly connected to their
potential to host Majorana bound states, a powerful ingredient in the search
for a robust, topologically protected, quantum information processing. In order
to produce such states, a method of choice is to induce superconductivity in
topological insulators. The engineering of the interplay between
superconductivity and the electronic properties of a topological insulator is a
challenging task and it is consequently very important to understand the
physics of simple superconducting devices such as Josephson junctions, in which
new topological properties are expected to emerge. In this article, we review
recent experiments investigating topological superconductivity in topological
insulators, using microwave excitation and detection techniques. More
precisely, we have fabricated and studied topological Josephson junctions made
of HgTe weak links in contact with two Al or Nb contacts. In such devices, we
have observed two signatures of the fractional Josephson effect, which is
expected to emerge from topologically-protected gapless Andreev bound states.
We first recall the theoretical background on topological Josephson junctions,
then move to the experimental observations. Then, we assess the topological
origin of the observed features and conclude with an outlook towards more
advanced microwave spectroscopy experiments, currently under development.Comment: Lectures given at the San Sebastian Topological Matter School 2017,
published in "Topological Matter. Springer Series in Solid-State Sciences,
vol 190. Springer
Voluntary motor drive: possible reduction in Tourette syndrome
Electrophysiologically, Tourette syndrome (TS) is characterized by shortened cortical silent period (CSP), reflecting decreased motor inhibition. However, voluntary versus involuntary aspects of inhibitory functions in TS are not well understood. Hence, investigating voluntary motor drive (VMD) could help to elucidate this issue. A group of 14 healthy adolescents was compared with subjects of same age suffering from TS with (NÂ =Â 6) and without (NÂ =Â 6) presence of distal tics. Basic resting and active motor thresholds (RMT and AMT, respectively) as well as suprathreshold transcranial magnetic stimulation-conditioned RMT and AMT were determined during the CSP. The difference between AMT and RMT was considered as VMD quantum. No group-differences were found in RMT or AMT. Subjects with distal tics showed reduced VMD compared to healthy controls while patients without distal tics did not differ from controls. In the second half of CSP, patients with distal tics showed also diminished VMD compared to tic-patients without distal tics. The findings support the notion, that TS shows possible reduction of VMD and is associated with central motor threshold alterations confined to the very motor networks related to the tics observed
Search for supersymmetric particles in scenarios with a gravitino LSP and stau NLSP
Sleptons, neutralinos and charginos were searched for in the context of
scenarios where the lightest supersymmetric particle is the gravitino. It was
assumed that the stau is the next-to-lightest supersymmetric particle. Data
collected with the DELPHI detector at a centre-of-mass energy near 189 GeV were
analysed combining the methods developed in previous searches at lower
energies. No evidence for the production of these supersymmetric particles was
found. Hence, limits were derived at 95% confidence level.Comment: 31 pages, 14 figure
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