Recent trends of SST in the Western Mediterranean basins from AVHRR Pathfinder data (1985-2007)

Climate change in the Mediterranean region cannot be understood without taking into account changes in the Mediterranean Sea, which is an important source of moisture and heat for the Mediterranean climate system. Many research papers have been published in the last two decades increasing our knowledge about long-term trends and inter-annual variability of temperature and salinity in the Western Mediterranean. Although recent changes have been better documented, there remain uncertainties because different results are obtained depending on the period of time analyzed or the geographic region selected. This paper analyses the regional, seasonal and decadal variability of sea surface temperature in the Western Mediterranean basins (Northern (Ligurian Sea and Gulf of Lions), Balearic, Algerian and Alboran) by means of thermal satellite images. Monthly data from the PO.DAAC (Physical Oceanography Distributed Active Archive Center) have been processed for the period 19852007. Results show an averaged warming linear trend of 0.03 °C/yr. This rate is higher during the spring (0.06 °C/yr) in all the basins and the highest values were registered in the Northern basin in June. The study suggests that an early warming of the Sea is occurring in all the basins during the spring, with an increment of 0.51 °C in the mean SST of April, May and June over the two decades studied. The analysis of thermal anomalies confirms the warming trend with a dominance of negative anomalies during 19851996 and a dominance of positive anomalies during the last decade (19972007). Intense anomalies are more frequent in the Northern basin

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited

Between the Panels: How the Interactions Between Commerce and Art Shape Superhero Comic Book Film Adaptations (2000-13)

This dissertation’s principal contribution to knowledge lies in its demonstration of the thesis that while economic considerations are ultimately determinant, artistic considerations have a degree of influence in shaping contemporary superhero comic book film adaptations and, as a consequence, the genre as a whole. Specifically, the dissertation argues that while the description of economic considerations as determinant in the last instance is accurate in relation to the long term development of the genre, in terms of each individual superhero film, a more accurate description is that economic considerations are determinant in the first instance. It focuses on the period 2000-13, at the beginning of which the superhero film genre was restarted by Bryan Singer’s X-Men and during which franchises such as The Dark Knight and Iron Man achieved unprecedented box office success for studios such as Warner Bros. and the newly created Marvel Studios. The dissertation considers how the relationship between art and commerce has been theorised historically, with particular emphasis on Marx’s mode of production and superstructure formulation and the subsequent modifications to it, including those of Louis Althusser. The dissertation uses a multiple case study comprised of four significant film franchises: Fox’s first X-Men trilogy, Universal and Marvel Studios’ Hulk films, Marvel Studios’ Iron Man trilogy and Warner Bros.’ Dark Knight trilogy. Each case study identifies specific changes made to the comic book source material in adaptation and by combining readings of the films with a consideration of their commercial contexts, demonstrates the extent to which each adaptation change is symptomatic of commercial or artistic logic

Good optical transparency is not an essential requirement for effective solar water disinfection (SODIS) containers

The efficacy of 10 L polypropylene (PP) transparent jerry cans (TJCs) to inactivate E. coli, MS2-phage and Cryptosporidium parvum via solar water disinfection (SODIS) was tested in well water or general test water under natural sunlight. Food-safe PP was used to manufacture the TJCs and a clarifying agent was added to improve optical transparency in the UV–visible range. 10 L PP TJCs and 2 L polyethylene terephthalate (PET) bottles were filled with well water, spiked separately with (~106 CFU/mL of E. coli, ~106 PFU/mL of MS2 phage and 5 ×105C. parvum oocysts per litre) and exposed to natural sunlight for 6 h. While the 10 L PP TJC prototype had poorer transparency (UV-B 0.001%, UV-A 4.29%, and visible 92% for TJCs without clarifier and UV-B 1.36%,UV-A 8.01%, and visible 90.01% for TJCs with clarifier) than standard 2 L PET (UV-B 0.72%, UV-A 10–85%, and visible 80–90%); log reduction values (LRVs) > 5, 2 and 0.8 for E. coli, MS2-phage, and C. parvum, respectively, were observed for the TJCs within six hours respectively, which is a minimum standard for drinking water established by the World Health Organisation (WHO). We observed similar inactivation kinetics for all three organisms in PP TJCs and PET bottles despite the poorer optical transparency properties of the SODIS jerry cans. Therefore, for effective SODIS, container optical transparency is not as important as previously believed. We conclude that good visible transparency is not a necessary requirement for containers intended for SODIS use

Maintenance and improvement of termal hydraulic system codes using results of OCDE experimentes (PKL, ROSA, ATLAS) and application to spanish nuclear power plants. CAMP-SPAIN project

[ES] La participación del Consejo de Seguridad Nuclear en diferentes programas experimentales internacionales en el ámbito de la termohidráulica dentro del marco de la NEA, ha permitido diseñar el alcance de una nueva etapa de las actividades del programa CAMPEspaña, que en la actualidad se centran en: - Análisis, simulación e investigación de aspectos específicos de seguridad de experimentos PKL3/0ECD y ATLAS/OECD. - Análisis de la aplicabilidad y/o extensión de los resultados de dichos proyectos para la seguridad, operación y disponibilidad de las plantas nucleares españolas. Ambos objetivos se llevan a cabo mediante la simulación de los experimentos y la aplicación a plantas españolas de las versiones más recientes de los códigos termohidraulicos de la US NRC (RELAP, TRACE). Otra aportación fina l de ambos tipos de análisis es la contribución de informes NUREG/IA sobre dichos análisis para CAMP. El desarrollo de las actividades se lleva a cabo por cinco grupos nacionales de investigación pertenecientes a las Universidades Politécnicas de Madrid, Valencia y Cataluña.[EN] CSN involvement in different nternational NEA expermental TH programmes has outlined the scope for a new period of CAMP-España activities, currently focused on the : - Analysisi, simulation and investigation of specific safety aspects of PKL3/OECD and ATLAS/OECD experimentes. - Analysisi of applicability and/or extension of the results in these projects to the safety, operation or availability of the Spanish nuclear power plants. Both objectives are carried out by simulating experiments and plant application with the last available versions of NRC TH codes (RELAPS or TRACE). A CAMP in-kind contribution (NUREG/IA) is aimed as final result of both types of analyses. Five different national research groups (from Technical Universities of Madrid, Valencia and Cataluña) are carrying out the development of these activities.Sánchez Perea, M.; Pérez, J.; Martorell Alsina, SS.; Carlos Alberola, S.; Villanueva López, JF.; Sanchez Saez, F.; Queral, C.... (2016). Mejora y mantenimiento de códigos termohidráulicos de sistema en base a resultados de los experimentos OECD (PKL, ROSA y ATLAS) y su aplicación a plantas españolas. Proyecto CAMP-ESPAÑA. Nuclear España. (373):37-42. http://hdl.handle.net/10251/99990S374237

Good optical transparency is not an essential requirement for effective solar water disinfection (SODIS) containers

The efficacy of 10 L polypropylene (PP) transparent jerry cans (TJCs) to inactivate E. coli, MS2-phage and Cryptosporidium parvum via solar water disinfection (SODIS) was tested in well water or general test water under natural sunlight. Food-safe PP was used to manufacture the TJCs and a clarifying agent was added to improve optical transparency in the UV–visible range. 10 L PP TJCs and 2 L polyethylene terephthalate (PET) bottles were filled with well water, spiked separately with (∼106 CFU/mL of E. coli, ∼106 PFU/mL of MS2 phage and 5 ×105C. parvum oocysts per litre) and exposed to natural sunlight for 6 h. While the 10 L PP TJC prototype had poorer transparency (UV-B 0.001%, UV-A 4.29%, and visible 92% for TJCs without clarifier and UV-B 1.36%, UV-A 8.01%, and visible 90.01% for TJCs with clarifier) than standard 2 L PET (UV-B 0.72%, UV-A 10–85%, and visible 80–90%); log reduction values (LRVs) > 5, 2 and 0.8 for E. coli, MS2-phage, and C. parvum, respectively, were observed for the TJCs within six hours respectively, which is a minimum standard for drinking water established by the World Health Organisation (WHO). We observed similar inactivation kinetics for all three organisms in PP TJCs and PET bottles despite the poorer optical transparency properties of the SODIS jerry cans. Therefore, for effective SODIS, container optical transparency is not as important as previously believed. We conclude that good visible transparency is not a necessary requirement for containers intended for SODIS use.</p

Good optical transparency is not an essential requirement for effective solar water disinfection (SODIS) containers

The efficacy of 10 L polypropylene (PP) transparent jerry cans (TJCs) to inactivate E. coli, MS2-phage and Cryptosporidium parvum via solar water disinfection (SODIS) was tested in well water or general test water under natural sunlight. Food-safe PP was used to manufacture the TJCs and a clarifying agent was added to improve optical transparency in the UV–visible range. 10 L PP TJCs and 2 L polyethylene terephthalate (PET) bottles were filled with well water, spiked separately with (∼106 CFU/mL of E. coli, ∼106 PFU/mL of MS2 phage and 5 ×105C. parvum oocysts per litre) and exposed to natural sunlight for 6 h. While the 10 L PP TJC prototype had poorer transparency (UV-B 0.001%, UV-A 4.29%, and visible 92% for TJCs without clarifier and UV-B 1.36%, UV-A 8.01%, and visible 90.01% for TJCs with clarifier) than standard 2 L PET (UV-B 0.72%, UV-A 10–85%, and visible 80–90%); log reduction values (LRVs) > 5, 2 and 0.8 for E. coli, MS2-phage, and C. parvum, respectively, were observed for the TJCs within six hours respectively, which is a minimum standard for drinking water established by the World Health Organisation (WHO). We observed similar inactivation kinetics for all three organisms in PP TJCs and PET bottles despite the poorer optical transparency properties of the SODIS jerry cans. Therefore, for effective SODIS, container optical transparency is not as important as previously believed. We conclude that good visible transparency is not a necessary requirement for containers intended for SODIS use.</p

Epidemiology of ataxia and hereditary spastic paraplegia in Spain: A cross-sectional study

Introduction: Ataxia and hereditary spastic paraplegia are rare neurodegenerative syndromes. We aimed to determine the prevalence of these disorders in Spain in 2019. Patients and methods: We conducted a cross-sectional, multicentre, retrospective, descriptive study of patients with ataxia and hereditary spastic paraplegia in Spain between March 2018 and December 2019. Results: We gathered data from a total of 1933 patients from 11 autonomous communities, provided by 47 neurologists or geneticists. Mean (SD) age in our sample was 53.64 (20.51) years; 938 patients were men (48.5%) and 995 were women (51.5%). The genetic defect was unidentified in 920 patients (47.6%). A total of 1371 patients (70.9%) had ataxia and 562 (29.1%) had hereditary spastic paraplegia. Prevalence rates for ataxia and hereditary spastic paraplegia were estimated at 5.48 and 2.24 cases per 100 000 population, respectively. The most frequent type of dominant ataxia in our sample was SCA3, and the most frequent recessive ataxia was Friedreich ataxia. The most frequent type of dominant hereditary spastic paraplegia in our sample was SPG4, and the most frequent recessive type was SPG7. Conclusions: In our sample, the estimated prevalence of ataxia and hereditary spastic paraplegia was 7.73 cases per 100 000 population. This rate is similar to those reported for other countries. Genetic diagnosis was not available in 47.6% of cases. Despite these limitations, our study provides useful data for estimating the necessary healthcare resources for these patients, raising awareness of these diseases, determining the most frequent causal mutations for local screening programmes, and promoting the development of clinical trialsFunding: The results of our study were partially presented at the 2017 and 2018 Annual Meetings of the Spanish Society of Neurology. Our study was partially funded by a grant from the Spanish Society of Neurology awarded to the lead author (Dr Gloria Ortega Suero), who was responsible for the database and data custody

Mapa epidemiológico transversal de las ataxias y paraparesias espásticas hereditarias en España

Resume: Introducción: Las ataxias (AT) y paraparesias espásticas hereditarias (PEH) son síndromes neurodegenerativos raros. Nos proponemos conocer la prevalencia de las AT y PEH en España en 2019. Pacientes y métodos: Estudio transversal, multicéntrico, descriptivo y retrospectivo de los pacientes con AT y PEH, desde marzo de 2018 a diciembre de 2019 en toda España. Resultados: Se obtuvo información de 1933 pacientes procedentes de 11 Comunidades Autónomas, de 47 neurólogos o genetistas. Edad media: 53,64 años ± 20,51 desviación estándar (DE); 938 varones (48,5%), 995 mujeres (51,5%). En 920 pacientes (47,6%) no se conoce el defecto genético. Por patologías, 1.371 pacientes (70,9%) diagnosticados de AT, 562 diagnosticados de PEH (29,1%). La prevalencia estimada de AT es 5,48/100.000 habitantes, y la de PEH es 2,24 casos/100.000 habitantes. La AT dominante más frecuente es la SCA3. La AT recesiva más frecuente es la ataxia de Friedreich (FRDA). La PEH dominante más frecuente es la SPG4, y la PEH recesiva más frecuente es la SPG7. Conclusiones: La prevalencia estimada de AT y PEH en nuestra serie es de 7,73 casos/100.000 habitantes. Estas frecuencias son similares a las del resto del mundo. En el 47,6% no se ha conseguido un diagnóstico genético. A pesar de las limitaciones, este estudio puede contribuir a estimar los recursos, visibilizar estas enfermedades, detectar las mutaciones más frecuentes para hacer los screenings por comunidades, y favorecer los ensayos clínicos. Abstract: Introduction: Ataxia and hereditary spastic paraplegia are rare neurodegenerative syndromes. We aimed to determine the prevalence of these disorders in Spain in 2019. Patients and methods: We conducted a cross-sectional, multicentre, retrospective, descriptive study of patients with ataxia and hereditary spastic paraplegia in Spain between March 2018 and December 2019. Results: We gathered data from a total of 1933 patients from 11 autonomous communities, provided by 47 neurologists or geneticists. Mean (SD) age in our sample was 53.64 (20.51) years; 938 patients were men (48.5%) and 995 were women (51.5%). The genetic defect was unidentified in 920 patients (47.6%). A total of 1371 patients (70.9%) had ataxia and 562 (29.1%) had hereditary spastic paraplegia. Prevalence rates for ataxia and hereditary spastic paraplegia were estimated at 5.48 and 2.24 cases per 100 000 population, respectively. The most frequent type of dominant ataxia in our sample was SCA3, and the most frequent recessive ataxia was Friedreich ataxia. The most frequent type of dominant hereditary spastic paraplegia in our sample was SPG4, and the most frequent recessive type was SPG7. Conclusions: In our sample, the estimated prevalence of ataxia and hereditary spastic paraplegia was 7.73 cases per 100 000 population. This rate is similar to those reported for other countries. Genetic diagnosis was not available in 47.6% of cases. Despite these limitations, our study provides useful data for estimating the necessary healthcare resources for these patients, raising awareness of these diseases, determining the most frequent causal mutations for local screening programmes, and promoting the development of clinical trials