The Utilization of Taro Leaf Silage (Alocasiamacrorhiza) with Marine Yeast Inoculant in Feed of Tambaqui (Colossoma Macropomum)

The purpose of this study was to determine the effect of silage use sente leaves on feed efficiency and growth of freshwater pomfret (Colossoma macropomum). The method used in the study is an experimental method by using a completely randomized design (CRD) of the factors with 5 level treatment and 3 replications., With treatment P0 (100% TK: 0% DS), P1 (80% TK: 20% DS ), P2 (60% TK: 40% DS), P3 (40% TK: 60% DS), P4 (20% TK: 80 DS) and P5 (0% TK: 100% DS). The results showed the use of leaf sente 100% was significantly lower than soybean meal, meaning can not fully replace soybean meal. But yielded significant results on the growth and retention of fish protein with the addition of 20 and 40% soybean meal in feed freshwater pomfret (Colossoma macropomum). The best treatment is obtained on the use of silage flour sente leaves as much as 40% with an average daily growth rate of 3.98% and feed efficiency of 45.63%

Association or Causation? Exploring the Oral Microbiome and Cancer Links

Several epidemiological investigations have found associations between poor oral health and different types of cancer, including colorectal, lung, pancreatic, and oral malignancies. The oral health parameters underlying these relationships include deficient oral hygiene, gingival bleeding, and bone and tooth loss. These parameters are related to periodontal diseases, which are directly and indirectly mediated by oral bacteria. Given the increased accessibility of microbial sequencing platforms, many recent studies have investigated the link between the oral microbiome and these cancers. Overall, it seems that oral dysbiotic states can contribute to tumorigenesis in the oral cavity as well as in distant body sites. Further, it appears that certain oral bacterial species can contribute to carcinogenesis, in particular, Fusobacterium nucleatum and Porphyromonas gingivalis, based on results from epidemiological as well as mechanistic studies. Yet, the strength of the findings from these investigations is hampered by the heterogeneity of the methods used to measure oral diseases, the treatment of confounding factors, the study design, the platforms employed for microbial analysis, and types of samples analyzed. Despite these limitations, there is an overall indication that the presence of oral dysbiosis that leads to oral diseases may directly and/or indirectly contribute to carcinogenesis. Proper methodological standardized approaches should be implemented in future epidemiological studies as well as in the mechanistic investigations carried out to explore these results. © International & American Associations for Dental Research 202

The impacts of geopolitical risks on the energy sector: Micro-level operative analysis in the European Union

Energy prices play a crucial role in combating geopolitical risks, especially for the major suppliers of energy resources. However, energy prices display a bilateral relationship with geopolitical risks in any economy. Any hike in the price of energy stimulates geopolitical risk factors and visa-versa. The consequences adversely impact economies and bring forth international tensions. This paper bridges a gap between the influence of geopolitical risks relating to energy and international tensions by analyzing micro-level operational measures. We deploy an empirical model to predict the energy sector and possible risk factors incorporating Eurostat data on twenty-seven states, from 2011 to 2020. This study collected a different energy variable to support the multiple regression model constructed by the “blocks” (hierarchical linear regression) method. The results suggest that geopolitical risks cause adverse effects on both the energy and other corporate sectors. The future direction of this research is to estimate how statistical model relationships may assist the corporate sector, and investors, in adopting mitigating measures to control upcoming geopolitical risks due to energy risks caused by geopolitical unrest.info:eu-repo/semantics/publishedVersio

Molecular and Genetic Aspects of Odontogenic Lesions

In this article we outline the molecular findings of select odontogenic tumors. In each section, we briefly review selected the clinicoradiographic, histologic, immunologic features, focusing on the molecular findings and their applications in practice. The understanding of molecular pathobiology at various other organ sites has developed quite rapidly in recent years, however much remains unknown about the genetic profile of odontogenic tumors. Improved understanding of mutations in odontogenic tumors may clarify classification schema and elucidate targets for novel therapies. Molecular testing will no doubt improve our understanding of odontogenic tumor pathogenesis and will likely be, someday, an important component of routine clinical practice and its role will only increase in the coming years

A consistent scalar-tensor cosmology for inflation, dark energy and the Hubble parameter

The authors are grateful for financial support to the Cruickshank Trust (CW), EPSRC/GG-Top (CW, JR), Omani Government (MA), Science Without Borders programme, CNPq, Brazil (DR), and STFC/CfFP (CW, AM, RB, JM). CW and AM acknowledge the hospitality of CERN, where this work was started. The University of Aberdeen and University of Edinburgh are charitable bodies registered in Scotland, with respective registration numbers SC013683 and SC005336.Peer reviewedPostprin

An Amelogenin Mutation Leads to Disruption of the Odontogenic Apparatus and Aberrant Expression of Notch I

BACKGROUND Amelogenins are highly conserved proteins secreted by ameloblasts in the dental organ of developing teeth. These proteins regulate dental enamel thickness and structure in humans and mice. Mice that express an amelogenin transgene with a P70T mutation (TgP70T) develop abnormal epithelial proliferation in an amelogenin null (KO) background. Some of these cellular masses have the appearance of proliferating stratum intermedium, which is the layer adjacent to the ameloblasts in unerupted teeth. As Notch proteins are thought to constitute the developmental switch that separates ameloblasts from stratum intermedium, these signaling proteins were evaluated in normal and proliferating tissues. METHODS Mandibles were dissected for histology and immunohistochemistry using Notch I antibodies. Molar teeth were dissected for western blotting and RT-PCR for evaluation of Notch levels through imaging and statistical analyses. RESULTS Notch I was immunolocalized to ameloblasts of TgP70TKO mice, KO ameloblasts stained, but less strongly, and wild-type teeth had minimal staining. Cells within the proliferating epithelial cell masses were positive for Notch I and had an appearance reminiscent of calcifying epithelial odontogenic tumor with amyloid-like deposits. Notch I protein and mRNA were elevated in molar teeth from TgP70TKO mice. CONCLUSION Expression of TgP70T leads to abnormal structures in mandibles and maxillae of mice with the KO genetic background and these mice have elevated levels of Notch I in developing molars. As cells within the masses also express transgenic amelogenins, development of the abnormal proliferations suggests communication between amelogenin producing cells and the proliferating cells, dependent on the presence of the mutated amelogenin protein

Energy efficiency of a flat-plate solar collector using thermally treated graphene-based nanofluids: Experimental study

© The Author(s) 2020. A covalent functionalization approach was utilized for the preparation of highly dispersed pentaethylene glycol-thermally treated graphene-water as the absorbing material inside a flat-plate solar collector. Four mass fractions of nanofluids were prepared (0.025, 0.05, 0.075, and 0.1 wt% pentaethylene glycol-thermally treated graphene-water). Graphene nanoparticles were characterized by energy dispersive X-ray analysis with a scanning electron microscope. Measurements of the thermophysical properties were subsequently carried out for the nanosuspensions. The raw investigation data were collected from an indoor flat-plate solar collector test setup. The experimental procedure included different sets of variables such as input temperatures of 303, 313, and 323 K; fluid mass flow rate of 0.00833, 0.01667, and 0.025 kg s−1; and heat flow density of 500, 750, and 1000 W m−2. The thermophysical tests of pentaethylene glycol-thermally treated graphene-water nanofluids showed a proportional increase against weight concentrations, while the specific heat power was reduced. The tests showed an increment in energy efficiency by increasing the fluid mass flow rate and heat input. By comparison, the thermal efficiency decreased with the increasing temperature of the fluid supply. Relative to the base fluid, the energy efficiency of pentaethylene glycol-thermally treated graphene/water-based flat-plate solar collector increased to 10.6%, 11%, and 13.1% at the three fluid mass flow rates. In conclusion, an exponential form was used to derive the thermal effectiveness of flat-plate solar collector based on the experimental data

Energy efficiency of a flat-plate solar collector using thermally treated graphene-based nanofluids: Experimental study

© The Author(s) 2020. A covalent functionalization approach was utilized for the preparation of highly dispersed pentaethylene glycol-thermally treated graphene-water as the absorbing material inside a flat-plate solar collector. Four mass fractions of nanofluids were prepared (0.025, 0.05, 0.075, and 0.1 wt% pentaethylene glycol-thermally treated graphene-water). Graphene nanoparticles were characterized by energy dispersive X-ray analysis with a scanning electron microscope. Measurements of the thermophysical properties were subsequently carried out for the nanosuspensions. The raw investigation data were collected from an indoor flat-plate solar collector test setup. The experimental procedure included different sets of variables such as input temperatures of 303, 313, and 323 K; fluid mass flow rate of 0.00833, 0.01667, and 0.025 kg s−1; and heat flow density of 500, 750, and 1000 W m−2. The thermophysical tests of pentaethylene glycol-thermally treated graphene-water nanofluids showed a proportional increase against weight concentrations, while the specific heat power was reduced. The tests showed an increment in energy efficiency by increasing the fluid mass flow rate and heat input. By comparison, the thermal efficiency decreased with the increasing temperature of the fluid supply. Relative to the base fluid, the energy efficiency of pentaethylene glycol-thermally treated graphene/water-based flat-plate solar collector increased to 10.6%, 11%, and 13.1% at the three fluid mass flow rates. In conclusion, an exponential form was used to derive the thermal effectiveness of flat-plate solar collector based on the experimental data