40 research outputs found

    HUMAN RESOURCE PRACTICES AND EMPLOYEE OUTCOMES: AN EXAMINATION OF PERFORMANCE, SATISFACTION AND DIVERSITY CLIMATE IN THE HOSPITALITY SECTOR OF SAUDI ARABIA

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    Tourism and related industries have become essential economic activities that play a significant role in the development, prosperity, and well-being of a country. The tourism and hotel sector in the Kingdom of Saudi Arabia (KSA) is currently undergoing significant development to diversify the national economy in line with the KSA Economic Vision 2030 Initiative. To align this sector with international standards in terms of job satisfaction and performance, human resource management practices (HRMPs) play a key role in determining the job satisfaction of employees in their various work environments. HRMPs include various job-related activities, training and development (T+D) programs, rewards, performance management, and promoting participation. The main focus of HRMPs is, therefore, to develop employees and create a positive work environment. Although there is active academic research worldwide on the potential relationship between HRMPs and employee performance, little has been written about this relationship in the Saudi hotel industry. This study examines the relationship between four HRMPs and job performance of employees based on job satisfaction, particularly attention to the impact of different work climates. A quantitative research design was used to obtain data from hotel sector managers in the KSA. Probability sampling was used to collect data from four cities in Saudi Arabia. Data was collected from 700 participants using a questionnaire. In addition, the structural equation modeling (SEM) technique was used to test the validity of the study\u27s measurement and structural model using SMART-PLS. The measurement model of SEM confirmed the reliability and validity. The obtained results showed that HRMPs have a positive relationship with employee job satisfaction and performance. Furthermore, employee job satisfaction moderates the relationship between HRMPs and employee job performance, while diversity climate also plays an important moderating role in this relationship. The current study contributes to social exchange theory (SET). The practical implications are that the HRM managers in the hotel industry will gain insights from this study about the positive impact of HRMPs on employee job satisfaction and performance in the KSA hotel industry

    Development of a Krypton target for Cyclone-30 at KFSH&RC

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    Introduction Krypton-81m is a radioactive gas with a half-life of 13 s, and found to be useful in many applications in nuclear medicine, particularly for lung perfusion studies and ventilations. Due to high demands for 81mKr, we have developed an automated Krypton system to be installed in one of the Cyclotron’s beamlines at King Faisal Specialist Hospital and Research Centre (KFSH&RC) and to deliver large activity of the radioactive gas. Material and Methods The effective cross section of producing 81Rb is between 15 and 30 MeV [1]. Therefore, range and stopping power of the effective cross section were calculated with respect to gas density of 0.0185 g/cm3. This value is equivalent to gas density at 5.0 bars at room temperature. SRIM calculations resulted in a range of 589 mm. However, due to limitation in fabricating such long target chamber, the target length is chosen to be 250 mm. Attached to the end of target body is a special water circulating flange ‘back-pool’, its purpose is to absorb the rest of the energy and protons Bragg peak. The target body is made of Aluminum with the inner part being electroplated with nickel. The target body is of conical shape. The target body is electrically isolated from other parts to allow accurate beam current reading. Full access to the target loading/unloading steps is made through touch screen technology (FIG. 2) for user access. Additionally, the target control system is designed to be protected through chain of interlock steps. The production cycle of 81Rb is explained as follow. Target is evacuated to approximately 10−3 mbar before being filled with natKr at pressure of 5 bars. At the end of bombardment, recovery of natKr is done via cryogenic vessel. Finally, the radioactivity is washed with KCl and pushed to Hotcells through the nitrogen gas for chemistry processing. Irradiation time was approximately 30 min. Results and Conclusion Experimental results clearly showed a fairly good activity of 81mKr as shown in TABLE 1. In all experiments, the radionuclidic purity of 81mKr was above 99.59%. 79mKr and 79Kr were also measured with a percentage of, respectively, 0.34 and 0.07 %. Special attention has to be drawn to last experiment where the yield significantly in-creased, due to the period where the KCl left inside the target (10 min) before pushing the solution to the Hotcell

    A Framework for Providing Augmented Reality as a Service Provided by Cloud Computing for E-Learning

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    The main objective of the proposed study is to develop an e-learning system using augmented reality technology one of the main problems faces using AR in education is the huge computational power needed to transfer 2D animation to enrich learning facilities. Such problem increases when using smart mobile devices that suffer from hardware limitation. A promising framework is used to utilize cloud services to support augmented reality applications on the cloud. Such method significantly reduces consumption of memory and processing units when dealing with large size videos or images. Hence the augmented reality processing is speeded up to meet the requirements of E-learning systems. The proposed work was conducted on 100 students from different academic levels in the first semester of the year 2022. Three experiments were conducted for different fields of education including two-dimensional images using Unity Program (3D Software) to draw 3D objects and Vufoira software development kit. The experimental results showed promising results as the application has the flexibility to work on different platforms. Moreover the consumed memory to run the application is reduced significantly. The results also showed high performance for the application when drawing complex 3D images and when dealing with different animations. The study supported with a detailed questioner that proofs the importance of AR in the field of E-learning

    Ga-Semicarbazone Complex: Potential PET Radiopharmaceutical for Tumor Imaging

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    In an attempt to develop new tumor imaging radiotracers with favorable biochemical properties, we have synthesized new 68 Ga-2-acetylpyridine semicarbazone ( 68 Ga-[APSC] 2 ) as a potential positron emission tomography (PET) tumor imaging agent using a straightforward and a one-step simple reaction. Radiochemical yield and purity were quantitative without HPLC purification. Biodistribution studies in nude mice model bearing human MDA-MB-231 cell line xenografts displayed significant tumor uptake of 68 Ga-[APSC] 2 radiotracer after 2 h postinjection (p.i.). The initial results demonstrate that 68 Ga-[APSC] 2 radiotracer may be useful probe for detecting and staging of hypoxic tumor using PET imaging modality

    Synthesis and Investigation of a Radioiodinated F3 Peptide Analog as a SPECT Tumor Imaging Radioligand

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    A radioiodinated derivative of the tumor-homing F3 peptide, (N-(2-{3-[125I]Iodobenzoyl}aminoethyl)maleimide-F3Cys peptide, [125I]IBMF3 was developed for investigation as a SPECT tumor imaging radioligand. For this purpose, we custom synthesized a modified F3 peptide analog (F3Cys) incorporating a C-terminal cysteine residue for site-specific attachment of a radioiodinated maleimide conjugating group. Initial proof-of-concept Fluorescence studies conducted with AlexaFluor 532 C5 maleimide-labeled F3Cys showed distinct membrane and nuclear localization of F3Cys in MDA-MB-435 cells. Additionally, F3Cys conjugated with NIR fluorochrome AlexaFluor 647 C2 maleimide demonstrated high tumor specific uptake in melanoma cancer MDA-MB-435 and lung cancer A549 xenografts in nude mice whereas a similarly labeled control peptide did not show any tumor uptake. These results were also confirmed by ex vivo tissue analysis. No-carrier-added [125I]IBMF3 was synthesized by a radioiododestannylation approach in 73% overall radiochemical yield. In vitro cell uptake studies conducted with [125I]IBMF3 displayed a 5-fold increase in its cell uptake at 4 h when compared to controls. SPECT imaging studies with [125I]IBMF3 in tumor bearing nude mice showed clear visualization of MDA-MB-435 xenografts on systemic administration. These studies demonstrate a potential utility of F3 peptide-based radioligands for tumor imaging with PET or SPECT techniques

    Solution chemistry of calix(4)arene amide derivatives: Applications in radiopharmaceuticals.

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    Following an overview in the field of calixarene chemistry given in the introduction, this thesis reports, i) The synthesis of p-text-butylcalix[4]arene tetraacetamides, thiophosphates and derivatives containing mixed functional groups and the characterisation by IR, NMR and microanalysis. ii) The solution thermodynamic of p-tert-butylcalix[4]arene tetradiisopropylacetamide and the transfer thermodynamics of this ligand from acetonitrile to various solvents. iii) Spectrophotometric, potentiometric and calorimetric studies on the interaction of p-tert-butylcalix[4]arene tetraacetamides and metal cations in butan-l-ol and in water saturated butan-l-ol at 298.15 K. Metal-ion complexes of p-tert-butylcalix[4]arene tetradiisopropylacetamide were isolated and characterised by IR, NMR and spectroscopy and microanalysis. In butan-l-ol, the selectivity of this ligand for metal cations follows the sequence Na+ > Cd2+ > Pb2+ > Zn2+ > Ag+. However, this sequence is altered in the water saturated solvent to an extent that the strong complexation observed for this ligand and zinc(II) in butan-l-ol is non-existent in the water saturated solvent. Using complexation data in conjunction with solution data of the host, the guest and the resulting complex, enthalpies of coordination (referred to the process which reactants and the product in the solid state) were calculated. iv) Extraction experiments in the water-butan-l-ol solvent system at 298.15 K in the presence of p-tert-butylcalix[4]arene tetradiisopropylacetamide were performed. The higher extraction of lead(II) relative to other metal cations from the aqueous solution to the organic phase in the presence of the ligand at low hydrogen-ion concentration is demonstrated. The extraction of radioactive lead(II) by the same ligand was investigated as a function of i) the pH of the aqueous phase ii) the ligand concentration in the organic phase. vi) A new polymeric material was obtained by attaching the ligand to the polymer. Final conclusions are drawn and suggestions for further work in this area are given
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