Alwyn h. gentry (enero 6, 1945 - agosto 3, 1993)

Las contribuciones de Al Gentry al conocimiento de la flora y la vegetación neotropicales marcaron un hito significativo en las áreas de la taxonomía, sistemática, ecología vegetal, biodiversidad y conservación. Al se caracterizó por ser un investigador incansable, un maestro como pocos y un devoto del conocimiento de la biología tropical, sobre la cual, de manera excelente, volcó todos los esfuerzos de procedimientos tradicionales

New Species of Siparuna (Siparunaceae) III

Three new species of Siparuna (Siparunaceae) are described, illustrated, and placed in a phylogenetic context: S. gentryana from western Ecuador and adjacent Colombia, S. lozaniana from the western Andes in Colombia, and S. vasqueziana from Amazonian Peru. In addition, Siparuna calantha from the Sierra Nevada de Santa Marta, originally described by Janet Perkins as a variety of a Mexican entity, is raised to species rank because its broader leaves and more numerous carpels readily distinguish it from its apparent closest relative, a species from the western Colombian Andes. Each of the species is known from several collections, which allowed the secure matching of sexual morphs in the three that are dioecious

Effects of Laryngeal Restriction on Pharyngeal Peristalsis and Biomechanics: Clinical Implications

To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to the inability to successfully overload and fatigue these muscles during their contraction, a necessary requirement for strength training. The purpose of this study was to test the hypothesis that applying resistance against anterosuperior movement of the hyolaryngeal complex will overload the pharyngeal muscles and by repetitive swallowing will result in their fatigue manifested by a reduction in pharyngeal peristaltic amplitude. Studies were done in two groups. In group 1 studies 15 healthy subjects (age: 42 ± 14 yr, 11 females) were studied to determine whether imposing resistance to swallowing using a handmade device can affect the swallow-induced hyolaryngeal excursion and related upper esophageal sphincter (UES) opening. In group 2, an additional 15 healthy subjects (age 56 ± 25 yr, 7 females) were studied to determine whether imposing resistance to the anterosuperior excursion of the hyolaryngeal complex induces fatigue manifested as reduction in pharyngeal contractile pressure during repeated swallowing. Analysis of the video recordings showed significant decrease in maximum deglutitive superior laryngeal excursion and UES opening diameter (P \u3c 0.01) due to resistive load. Consecutive swallows against the resistive load showed significant decrease in pharyngeal contractile integral (PhCI) values (P \u3c 0.01). Correlation analysis showed a significant negative correlation between PhCI and successive swallows, suggesting “fatigue” (P \u3c 0.001). In conclusion, repeated swallows against a resistive load induced by restricting the anterosuperior excursion of the larynx safely induces fatigue in pharyngeal peristalsis and thus has the potential to strengthen the pharyngeal contractile function

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

Indexación: Web of Science; Scopus.Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply modifications in dendritic cytoskeleton. Rho GTPases are regulators of actin dynamics through their effector Rho kinase. We have reported that chronic stress promotes depressive-like behaviors in rats along with dendritic spine loss in apical dendrites of hippocampal pyramidal neurons, changes associated with Rho kinase activation. The present study proposes that the Rho kinase inhibitor Fasudil may prevent the stress-induced behavior and dendritic spine loss. Methods: Adult male Sprague-Dawley rats were injected with saline or Fasudil (i.p., 10 mg/kg) starting 4 days prior to and maintained during the restraint stress procedure (2.5 h/d for 14 days). Nonstressed control animals were injected with saline or Fasudil for 18 days. At 24 hours after treatment, forced swimming test, Golgi-staining, and immuno-western blot were performed. Results: Fasudil prevented stress-induced immobility observed in the forced swimming test. On the other hand, Fasudiltreated control animals showed behavioral patterns similar to those of saline-treated controls. Furthermore, we observed that stress induced an increase in the phosphorylation of MYPT1 in the hippocampus, an exclusive target of Rho kinase. This change was accompanied by dendritic spine loss of apical dendrites of pyramidal hippocampal neurons. Interestingly, increased pMYPT1 levels and spine loss were both prevented by Fasudil administration. Conclusion: Our findings suggest that Fasudil may prevent the development of abnormal behavior and spine loss induced by chronic stress by blocking Rho kinase activity.https://academic.oup.com/ijnp/article/20/4/336/263217

Wrightia.

v.5 (1972-1977

Path ORAM: An Extremely Simple Oblivious RAM Protocol

We present Path ORAM, an extremely simple Oblivious RAM protocol with a small amount of client storage. Partly due to its simplicity, Path ORAM is the most practical ORAM scheme known to date with small client storage. We formally prove that Path ORAM has a O(log N) bandwidth cost for blocks of size B = Omega(log^2 N) bits. For such block sizes, Path ORAM is asymptotically better than the best known ORAM schemes with small client storage. Due to its practicality, Path ORAM has been adopted in the design of secure processors since its proposal

The Shaman\u27s Apprentice by Lynne Cherry and Mark J. Plotkin

Book Revie

A Framework for Statistically Sender Private OT with Optimal Rate

Statistical sender privacy (SSP) is the strongest achievable security notion for two-message oblivious transfer (OT) in the standard model, providing statistical security against malicious receivers and computational security against semi-honest senders. In this work we provide a novel construction of SSP OT from the Decisional Diffie-Hellman (DDH) and the Learning Parity with Noise (LPN) assumptions achieving (asymptotically) optimal amortized communication complexity, i.e. it achieves rate 1. Concretely, the total communication complexity for $k$ OT instances is $2k(1+o(1))$, which (asymptotically) approaches the information-theoretic lower bound. Previously, it was only known how to realize this primitive using heavy rate-1 FHE techniques [Brakerski et al., Gentry and Halevi TCC\u2719]. At the heart of our construction is a primitive called statistical co-PIR, essentially a a public key encryption scheme which statistically erases bits of the message in a few hidden locations. Our scheme achieves nearly optimal ciphertext size and provides statistical security against malicious receivers. Computational security against semi-honest senders holds under the DDH assumption

Introduction of cognitive support technologies (CST) for job seekers

Research shows that adults with cognitive impairment can benefit from cognitive support technologies (CST), and combined with good coping strategies, these technologies can help facilitate inclusion in the labour market. Experience from our rehabilitation work in Norway shows that introducing CST to persons with Asperger’s syndrome and/or attention-deficit hyperactivity disorder (ADHD) can be challenging. This study describes and discusses factors that can promote or inhibit the introduction of CST in vocational rehabilitation services. These descriptions are based on twelve months of ethnographic fieldwork in two vocational rehabilitation programmes in Norway. We describe how adequate time, mandatory integration of technology in activities, recognition of and faith in the individual's ability to eventually find a job as part of a professional strategy, and the use of the job seekers’ own technologies, are intertwined and interdependent factors that promote the introduction of CST. The inhibiting factors we describe may be related to the diagnosis of the typical challenges faced by adults suffering from ADHD and/or Asperger’s, such as organizational challenges, procrastination or general difficulty in doing things in a new way.publishedVersio