An integrated new product development model for the Turkish electronics industry

The aim of this study is to report on an integrated model of new product development (NPD) and the analysis of factors, which have a significant effect on new product development success. First, an integrated NPD model based on past research findings and suggestions of several researchers is built. A three-step model is constructed and is tested through a series of statistical tests and analysis. The data for the testing of the model is provided by an empirical study conducted in the Turkish electronics industry. Some practices for successful NPD are suggested

IMMIGRATIONS FROM THE BALKANS TO TURKEY AND IMMIGRANT SETTTLEMENTS IN WESTERN ANATOLIA

It is well known that many countries fought for supremacy over the Balkans throughout the history, because of which at least some groups in the region were displaced. Turkey got heavily affected by these population movements. Especially,following the end of Ottoman sovereignty in the Balkan, struggles for sovereignty and related problems have showed up and continued up until the present time.Meanwhile, thousands of people were displaced from their homelands.Like the Balkans population in Western Anatolia have always been on the move dueto population movements and political struggles between the East and the West thathave taken place for centuries. Such population movements led to very sorrowful consequences for the Turkish and Muslims particularly from 1787 to the present time. People emigrated from the Balkans and immigrated to Anatolia in great numbers as a result of the Russo-Turkish Wars between 1787 and 1792, which was followed by immigrations after the Russo-Turkish War in 1877-1878, the BalkanWar in 1912-1914, the World War I in 1914-1918. Immigrations to Turkey went onowing to population exchanges as required by the Lausanne Treaty in 1923, the unsurpressable unrests in the Balkans in the following years, and the Bosnian Warbetween 1990 and 1995. A good many immigrant settlements have mushroomed across the country as a consequence of these immigrations to Turkey, which havecontinued from time to time over some 200 years. Physical and human geography played an important part in the distribution of immigrant settlements. Aconsiderable amount of immigrants have settled in Western Anatolia, which is today densely populated with immigrants

A European Organization for Research and Treatment of Cancer-International Antimicrobial Therapy Group Study of Secondary Infections in Febrile, Neutropenic Patients with Cancer

Background. Neutropenic patients with cancer may develop several episodes of fever and infection during chemotherapy-induced myeloaplasia. Methods. To identify risk factors for secondary infectious episodes among patients who responded to initial antibiotic therapy, we retrospectively analyzed 2 consecutive, prospective, randomized clinical trials performed by the International Antimicrobial Therapy Group of the European Organization for Research and Treatment of Cancer during 1991-1994. Results. Of 1720 patients with their first episode of febrile neutropenia, 836 responded to the initial antibiotic regimen and were therefore suitable for our analysis. A secondary infection was observed in 129 (15%) of 836 patients that occurred at a median of 10 days (range, 1-28 days) after the onset of the primary febrile episode. Factors at both baseline and day 4 were analyzed. Age of >16 years (odds ratio [OR], 3.46; P < .001), acute leukemia in first induction (OR, 3.17; P < .001), presence of intravenous line (OR, 1.88; P = .04), severe neutropenia (defined as an absolute granulocyte count of <100 cells/mm3) on day 4 (OR, 2.72; P < .001), and type of documentation of the primary episode (i.e., microbiologically documented cause or unexplained fever; OR, 2.56; P = .001) were found to be risk factors for secondary infection. The risk of death was higher among patients who developed a secondary infectious episode than among those who did not (5.4% vs. 1.4%; P < .01). Conclusions. The clinical parameters described above may help to identify neutropenic patients at risk of developing secondary infectio

A non-parametric Bayesian model for joint cell clustering and cluster matching: identification of anomalous sample phenotypes with random effects

BACKGROUND: Flow cytometry (FC)-based computer-aided diagnostics is an emerging technique utilizing modern multiparametric cytometry systems.The major difficulty in using machine-learning approaches for classification of FC data arises from limited access to a wide variety of anomalous samples for training. In consequence, any learning with an abundance of normal cases and a limited set of specific anomalous cases is biased towards the types of anomalies represented in the training set. Such models do not accurately identify anomalies, whether previously known or unknown, that may exist in future samples tested. Although one-class classifiers trained using only normal cases would avoid such a bias, robust sample characterization is critical for a generalizable model. Owing to sample heterogeneity and instrumental variability, arbitrary characterization of samples usually introduces feature noise that may lead to poor predictive performance. Herein, we present a non-parametric Bayesian algorithm called ASPIRE (anomalous sample phenotype identification with random effects) that identifies phenotypic differences across a batch of samples in the presence of random effects. Our approach involves simultaneous clustering of cellular measurements in individual samples and matching of discovered clusters across all samples in order to recover global clusters using probabilistic sampling techniques in a systematic way. RESULTS: We demonstrate the performance of the proposed method in identifying anomalous samples in two different FC data sets, one of which represents a set of samples including acute myeloid leukemia (AML) cases, and the other a generic 5-parameter peripheral-blood immunophenotyping. Results are evaluated in terms of the area under the receiver operating characteristics curve (AUC). ASPIRE achieved AUCs of 0.99 and 1.0 on the AML and generic blood immunophenotyping data sets, respectively. CONCLUSIONS: These results demonstrate that anomalous samples can be identified by ASPIRE with almost perfect accuracy without a priori access to samples of anomalous subtypes in the training set. The ASPIRE approach is unique in its ability to form generalizations regarding normal and anomalous states given only very weak assumptions regarding sample characteristics and origin. Thus, ASPIRE could become highly instrumental in providing unique insights about observed biological phenomena in the absence of full information about the investigated samples

The Relationship between Superstitions, Metaphors, and Advertising

The study evaluates superstitions and faiths that have maintained their contemporariness and occupy a significant place in people’s lives from the different perspectives of believers and non-believers; exploring their reasons for remaining contemporary as well as the fields in which they are readily observed. The article addresses the concepts of superstitious faiths and behaviors, and their conceptual boundaries; the current and naive connection between superstitions, marketing and advertising, to fill a gap in the current discourse. The study does not make normative value judgments on what is superstitious; instead, it is concerned with why we need them, and how they are internalized as well as their proliferation. The goal is to probe how this sustainability and positioning as well as the need for their spiritual auras have been maintained across generations

Visual acuity and quality of life in dry eye disease: Proceedings of the OCEAN group meeting

This article was developed from a roundtable meeting held on 16 January 2015 by the OCEAN group in Paris, France

Cultural destination attributes, overall tourist satisfaction and tourist loyalty: First Timers versus Repeaters

This paper analyses the effects of the cultural attributes of tourist destinations on the satisfaction levels of visitors and the impact of this satisfaction rating on visitor loyalty. Additionally, a multiple-group analysis was conducted to compare the responses of first-time visitors and repeat visitors. For this study, a self-administered questionnaire was used to survey 411 international tourists who were visiting Istanbul, Turkey, through convenience sampling. The findings indicated that cultural attractions at the destination impacted the overall satisfaction rating of the visitors, and that this specific satisfaction rating determined the loyalty of the tourist to return to the destination. This relationship between cultural attractions, satisfaction and visitor loyalty was a significant factor for both groups

POLITICAL COMMUNICATION ON SARIKAMIS ATTACK OPERATION

I. Dünya Sava?ı’nda Rusya’ya kar?ı açılan Kafkas Cephesi, Türklerin, Türkistan Coğrafyasına açılan kapısı olarakgörülmesi ve Anadolu müdafaasında ilk cephe olması sebebiyle önem arz etmektedir. Bu cephede Rusların, gücünü fark edenve geleceği ön gören Enver Pa?a, Kafkasya’ya açılan kapıyı Ruslara devretmemek arzusu ile bir taarruz planı hazırlamı?tır. Buplan öncesi Enver Pa?a’nın, öngörülü tavrı ile Kafkasya ve Rusya bölgesine gönderdiği Türk ajanlar ile ba?lamı?; sonra taarruzile devam etmi?tir. Taarruz Ruslar tarafından ?a?kınlık ve psikolojik hezeyan olarak kar?ılanırken, Enver Pa?a komutasındakiOsmanlı, psikolojik zaferi elde etmi?tir ve sıcak kar?ıla?mada iki taraf da çarpı?arak kar?ılıklı zayiat vermi?tir. Ruskaynaklarına Türk azmi, inancı ve cesaretini yazdırarak, dü?man kaleminden ba?arı yazdıran bir harekât olmu?tur. Uzunvadede Enver Pa?a’nın gönderdiği ajanlar tarafından çıkartılan isyan, Rusya’da ihtilale sebep olmu? Rusya sınırlardantamamen çekilmi? ve Sarıkamı? ?hata Harekâtı uzun vadeli bir zaferin adı olarak, tarihin üzeri örtülmü? gerçekleri arasınayazılmı?tır. 70.000 ki?i olan Osmanlı III. Ordusu ile yapılan harekâtta, 90.000 askerin hiç kur?un atmadan ve Rusya ilekar?ıla?madan donarak öldürüldüğü iddiası ile gündem olu?turma gayesinde olan bir güruh tarafından tarihin gerçekleriörtülmü? ve Enver Pa?a karalanarak Sarıkamı? Harekâtı uzun yıllar büyük bir hezeyan olarak anılmı?tır. Rus ve Osmanlıkaynaklarında kayıplar ayrı ayrı dü?mü?ken, kaynaklara dayandırılmadan yapılan bu gerçekleri karalama hareketi, bugün günyüzüne çıkmı?tır. Bu çalı?mamızda; Sarıkamı? ?hata Harekâtı’nın öncesi ve sonrası durum değerlendirmesine gerçeklerpenceresinden objektif olarak bakarak, olu?turulmu? gündemi tarihle yargılayacağız