Extracting B→K∗B \to K^* Form Factors from Data

We extract ratios of $B \to K^*$ form factors at low hadronic recoil from recent data on $B \to K^* \mu^+ \mu^-$ decays in a model-independent way. The presented method will improve in the future with further (angular) studies in semileptonic rare B-decays and advance our understanding of form factors, which are important inputs in precision tests of the Standard Model

Patterns of genetic diversity and linkage disequilibrium in a highly structured Hordeum vulgare association-mapping population for the Mediterranean basin

Population structure and genome-wide linkage disequilibrium (LD) were investigated in 192 Hordeum vulgare accessions providing a comprehensive coverage of past and present barley breeding in the Mediterranean basin, using 50 nuclear microsatellite and 1,130 DArT® markers. Both clustering and principal coordinate analyses clearly sub-divided the sample into five distinct groups centred on key ancestors and regions of origin of the germplasm. For given genetic distances, large variation in LD values was observed, ranging from closely linked markers completely at equilibrium to marker pairs at 50 cM separation still showing significant LD. Mean LD values across the whole population sample decayed below r 2 of 0.15 after 3.2 cM. By assaying 1,130 genome-wide DArT® markers, we demonstrated that, after accounting for population substructure, current genome coverage of 1 marker per 1.5 cM except for chromosome 4H with 1 marker per 3.62 cM is sufficient for whole genome association scans. We show, by identifying associations with powdery mildew that map in genomic regions known to have resistance loci, that associations can be detected in strongly stratified samples provided population structure is effectively controlled in the analysis. The population we describe is, therefore, shown to be a valuable resource, which can be used in basic and applied research in barle

Mapping adaptation of barley to droughted environments

Identifying barley genomic regions influencing the response of yield and its components to water deficits will aid in our understanding of the genetics of drought tolerance and the development of more drought tolerant cultivars. We assembled a population of 192 genotypes that represented landraces, old, and contemporary cultivars sampling key regions around the Mediterranean basin and the rest of Europe. The population was genotyped with a stratified set of 50 genomic and EST derived molecular markers, 49 of which were Simple Sequence Repeats (SSRs), which revealed an underlying population sub-structure that corresponded closely to the geographic regions in which the genotypes were grown. A more dense whole genome scan was generated by using Diversity Array Technology (DArT®) to generate 1130 biallelic markers for the population. The population was grown at two contrasting sites in each of seven Mediterranean countries for harvest 2004 and 2005 and grain yield data collected. Mean yield levels ranged from 0.3 to 6.2 t/ha, with highly significant genetic variation in low-yielding environments. Associations of yield with barley genomic regions were then detected by combining the DArT marker data with the yield data in mixed model analyses for the individual trials, followed by multiple regression of yield on markers to identify a multi-locus subset of significant markers/QTLs. QTLs exhibiting a pre-defined consistency across environments were detected in bins 4, 6, 6 and 7 on barley chromosomes 3H, 4H, 5H and 7H respectivel

A Survey of Quality of Service Differentiation Mechanisms for Optical Burst Switching Networks

Cataloged from PDF version of article.This paper presents an overview of Quality of Service (QoS) differentiation mechanisms proposed for Optical Burst Switching (OBS) networks. OBS has been proposed to couple the benefits of both circuit and packet switching for the ‘‘on demand’’ use of capacity in the future optical Internet. In such a case, QoS support imposes some important challenges before this technology is deployed. This paper takes a broader view on QoS, including QoS differentiation not only at the burst but also at the transport levels for OBS networks. A classification of existing QoS differentiation mechanisms for OBS is given and their efficiency and complexity are comparatively discussed. We provide numerical examples on how QoS differentiation with respect to burst loss rate and transport layer throughput can be achieved in OBS networks. © 2009 Elsevier B.V. All rights reserved

The Mitochondrial Translocator Protein and Arrhythmogenesis in Ischemic Heart Disease

Mitochondrial dysfunction is a hallmark of multiple cardiovascular disorders, including ischemic heart disease. Although mitochondria are well recognized for their role in energy production and cell death, mechanisms by which they control excitation-contraction coupling, excitability, and arrhythmias are less clear. The translocator protein (TSPO) is an outer mitochondrial membrane protein that is expressed in multiple organ systems. The abundant expression of TSPO in macrophages has been leveraged to image the immune response of the heart to inflammatory processes. More recently, the recognition of TSPO as a regulator of energy-dissipating mitochondrial pathways has extended its utility from a diagnostic marker of inflammation to a therapeutic target influencing diverse pathophysiological processes. Here, we provide an overview of the emerging role of TSPO in ischemic heart disease. We highlight the importance of TSPO in the regenerative process of reactive oxygen species (ROS) induced ROS release through its effects on the inner membrane anion channel (IMAC) and the permeability transition pore (PTP). We discuss evidence implicating TSPO in arrhythmogenesis in the settings of acute ischemia-reperfusion injury and myocardial infarction

Effect of surface contamination on interfacial mass transfer rate

The influence of surface contamination upon the mass transfer rate of a low diffusivity gas across a flat surface is studied using direct numerical simulations. The interfacial mass transfer is driven by isotropic turbulence diffusing from below. Similar to Shen et al. (J. Fluid Mech. 506, 2004, pp. 79-115) the surface contamination is modelled by relating the normal gradient of the horizontal velocities at the top to the horizontal gradients of the surfactant concentrations. A broad range of contamination levels is considered, including clean to severely contaminated conditions. The time-averaged results show a strong correlation between the gas transfer velocity and the clean surface fraction of the surface area. In the presence of surface contamination the mass transfer velocity KL is found to scale as a power of the Schmidt number, i.e. Sc−q, where q smoothly transitions from q = 1/2 for clean surfaces to q = 2/3 for very dirty interfaces. A power law KL ∝ Sc−q is proposed in which both the exponent q and the constant of proportionality become functions of the clean surface fraction

Measurement of the CP-violating phase phi(s) from B-s(0) -> J/psi pi(+)pi(-) decays in 13 TeV pp collisions

Decays of B-s(0) and (B) over bar (0)(s) mesons into J/psi pi(+)pi(-) final states are studied in a data sample corresponding to 1.9 fb(-1) of integrated luminosity collected with the LHCb detector in 13 TeV pp collisions. A time-dependent amplitude analysis is used to determine the final-state resonance contributions, the CP-violating phase phi(s) = -0.057 +/- 0.060 +/- 0.011 rad, the decay-width difference between the heavier mass B-s(0) eigenstate and the B-0 meson of -0.050 +/- 0.004 +/- 0.004 ps(-1), and the CP-violating parameter vertical bar lambda vertical bar = 1.01(-0.06)(+0.08) +/- 0.03, where the first uncertainty is statistical and the second systematic. These results are combined with previous LHCb measurements in the same decay channel using 7 TeV and 8 TeV pp collisions obtaining phi(s) = 0.002 +/- 0.044 +/- 0.012 rad, and vertical bar lambda vertical bar = 0.949 +/- 0.036 +/- 0.019. (C) 2019 The Author. Published by Elsevier B.V