Ownership and Use of Mobile Phone – A Population based Study Physical Education and Sport College Students in Turkey

AbstractPurposeRecent years have seen a rapid increase in the use of mobile phones, raising concers about possible adverse health effecets. The present study aims to find out the prevalence of mobile phone usage of the students educated in sports training in the university.Material and MethodsThis cross-sectional study was carried out 01 October and 31 May in 2010. 1325 students (94.5%) out of total 1402 studying in the Department of Physical Education and Sports Schools of five different universities located on the Black Sea accepted to participate in the study. A questionnaire form was applied to the participants under the observation of the researchers.ResultsIn the study, although 1036 (78.2%) of the students said that mobile phones had adverse health effects, it was found that 1305 (98.5%) students used mobile phones, 251 (18.9%) had more than one mobile phone and each talk took the least median 3 (1-14) minutes and the most median 10 (1-14) minutes. 506 (38.8%) of the mobile phone users said that they talked on the mobile phone while driving.ConclusionAs a result, it was found that the use of mobile phones among the students was common and they usually carried their mobile phones on them during their classes. Even though mobile phones are important for those students studying away from their homes to keep in touch with their families, it is suggested that they should pay attention to some practices while using their mobile phones

Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis

Background: Hemophagocytic lymphohistiocytosis (HLH) is a rapid-onset, potentially fatal hyperinflammatory syndrome. A prompt molecular diagnosis is crucial for appropriate clinical management. Here, we validated and prospectively evaluated a targeted high-throughput sequencing approach for HLH diagnostics. Methods: A high-throughput sequencing strategy of 12 genes linked to HLH was validated in 13 patients with previously identified HLH-associated mutations and prospectively evaluated in 58 HLH patients. Moreover, 2504 healthy individuals from the 1000 Genomes project were analyzed in silico for variants in the same genes. Results: Analyses revealed a mutation detection sensitivity of 97.3 %, an average coverage per gene of 98.0 %, and adequate coverage over 98.6 % of sites previously reported as mutated in these genes. In the prospective cohort, we achieved a diagnosis in 22 out of 58 patients (38 %). Genetically undiagnosed HLH patients had a later age at onset and manifested higher frequencies of known secondary HLH triggers. Rare, putatively pathogenic monoallelic variants were identified in nine patients. However, such monoallelic variants were not enriched compared with healthy individuals. Conclusions: We have established a comprehensive high-throughput platform for genetic screening of patients with HLH. Almost all cases with reduced natural killer cell function received a diagnosis, but the majority of the prospective cases remain genetically unexplained, highlighting genetic heterogeneity and environmental impact within HLH. Moreover, in silico analyses of the genetic variation affecting HLH-related genes in the general population suggest caution with respect to interpreting causality between monoallelic mutations and HLH. A complete understanding of the genetic susceptibility to HLH thus requires further in-depth investigations, including genome sequencing and detailed immunological characterization.Peer reviewe

ROLE OF FACET JOINT ORIENTATION AND FACET TROPISM IN NONSPESIFIC LOW BACK PAIN

Background: Low Back Pain is a complaint at least once we experience all through our life. Although low back pain can be caused by several reasons, mostly low back pain due to nonspecific reasons can be encountered. In this study, our main goal is to examine facet tropism types and facet joint orientation in patients with nonspecific low back pain we have grouped according to age and determine if there is a relationship between the low back pain and facet joint morphology. Patients and methods: We have retrospectively examined magnetic resonance imaging of 135 patients who applied to the neurosurgery clinic with low back pain complaint in the period of 2017-2018 year. For each phenomenon, facet joint angles have been measured at all vertebra levels. Average values of facet joint angles have been taken and facet orientation has been determined. The difference between right and left facet joint angle has been calculated; degree and type of facet tropism have been determined. Results: It has been observed that facet joint orientation at L1-2 level was more coronalized in age group of 70-80 when compared to age group of 10-20. ‘No type’ facet tropism has been observed in majority of the phenomenon and no significant difference has been observed between lumbar levels and age groups. Conclusion: As a result of our study; it has been concluded that facet joint orientation and facet tropism are not effective in the etiology of nonspecific low back pain. Furthermore, facet tropism is not related to age and maybe it is an inborn characteristic

Magnetic nanoparticles for diagnosis and treatment

Cancer is a complex disease in which certain cells in the body grow uncontrollably and spread to other parts of the body. Although there have been advances observed in the diagnosis and treatment of cancer, many studies are conducted to eliminate the side effects that occur during treatment. Magnetic nanoparticles (MNPs) are of great interest in the field of cancer diagnosis and treatment due to their magnetic features, biocompatibility, and stability. These features allow them to be used as a contrast agent for magnetic resonance (MR) imaging as a therapeutic system with a drug release system and hyperthermia. MNP-based imaging, drug release systems, and hyperthermia treatments have been studied by researchers and reported to be promising for the treatment of various types of cancer. Although the clinical applications of MNPs for cancer treatment are still controversial, researchers think that MNPs will play an important role in meeting health needs in the future. In this review, we present advances in in-vitro and in-vivo research for diagnosis and treatment, besides an overview of the basic technical principles of MNPs. [Med-Science 2022; 11(2.000): 934-41

Ownership And Use Of Mobile Phone-A Population Based Study Physical Education And Sport College Students In Turkey

Purpose: Recent years have seen a rapid increase in the use of mobile phones, raising concers about possible adverse health effecets. The present study aims to find out the prevalence of mobile phone usage of the students educated in sports training in the university. Material and Methods: This cross-sectional study was carried out 01 October and 31 May in 2010. 1325 students (94.5%) out of total 1402 studying in the Department of Physical Education and Sports Schools of five different universities located on the Black Sea accepted to participate in the study. A questionnaire form was applied to the participants under the observation of the researchers. Results: In the study, although 1036 (78.2%) of the students said that mobile phones had adverse health effects, it was found that 1305 (98.5%) students used mobile phones, 251 (18.9%) had more than one mobile phone and each talk took the least median 3 (1-14) minutes and the most median 10 (1-14) minutes. 506 (38.8 %) of the mobile phone users said that they talked on the mobile phone while driving. Conclusion: As a result, it was found that the use of mobile phones among the students was common and they usually carried their mobile phones on them during their classes. Even though mobile phones are important for those students studying away from their homes to keep in touch with their families, it is suggested that they should pay attention to some practices while using their mobile phones

Effects of exposure to electromagnetic field (1.8/0.9 GHz) on testicular function and structure in growing rats

The aim of our study was to evaluate the possible effects of whole-body electromagnetic field (EMF) exposure on reproduction in growing male rats. Male albino Wistar rats (2 days old) were exposed to EMF 1800 and 900 MHz for 2 h continuously per day for 90 days. Sham control was kept under similar conditions except that the field was not applied for the same period. After blood samples were collected, the animals were sacrificed 24 h after the last exposure and the tissues of interest were harvested. The mean plasma total testosterone showed similarity among the two study groups and was significantly higher than the sham control rats. The percentage of epididymal sperm motility was significantly higher in the 1800 MHz group (P < 0.05). The morphologically normal spermatozoa rates were higher and the tail abnormality and total percentage abnormalities were lower in the 900 MHz group (P < 0.05). Histopathologic parameters in the 1800 MHz group were significantly higher (P < 0.05). In conclusion, the present study indicated that exposure to electromagnetic wave caused an increase in testosterone level, epididymal sperm motility (forward), and normal sperm morphology of rats. As a consequences, 1800 and 900 MHz EMF could be considered to be a cause of precocious puberty in growing rats. (C) 2011 Elsevier Ltd. All rights reserved

Investigating academic performance of migrant students: A system dynamics perspective with an application to Turkey

The system dynamics approach is a holistic way of solving problems in real-time scenarios. This is a powerful methodology of modern Operational Research for framing, analyzing, and discussing complex issues and problems. System dynamics modeling is often the background of a systemic thinking approach and has become a management and organizational development paradigm. This paper proposes a system dynamics model for studying the factors that impact the academic performance of 1st to 8th grade primary school students residing in poor migrant neighborhoods. The data used in the model are based upon the perception of teachers who are the subjects of a survey conducted in public schools located mainly in the inner squatter and outer squatter districts of Turkish cities. Squatter districts are subjected to large shifts of population as a result of interregional and urban-rural migration, and they pose educational, social and behavioral challenges. The system dynamics model proposed here builds up relationships between variables that affect academic performance of migrant students. The goal of the model is to identify best government policies that might improve the system state in the minimum time span. System simulation results show that the government should implement policies that target many aspects of the system concurrently in order to improve student academic quality