Delta Scuti yıldızlarında çoğul dönemli değişmeler

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Cystatin C can be affected by nonrenal factors: A preliminary study on leukemia

Objective: The aim of this study was to evaluate the influence of malignancy and the impact of nephrotoxic drugs used in bone marrow transplantation (BMT) on the circulating levels of cystatin C in leukemia. Methods: We studied nineteen patients (eleven men and eight women; mean age 30.1 ± 11.2, 27.9 ± 7.1 years) with acute lymphoblastic leukemia, acute myeloid leukemia and chronic myeloid leukemia. Cystatin C, urea, creatinine and creatinine clearance (CrCl) were measured 24 h before BMT, 1 week after BMT, 2 weeks after BMT and 3 weeks after BMT. The control group consisted of twenty healthy adults, and the mean age was 29.1 ± 8.9. Results: At the pretransplantation period, values of cystatin C were significantly higher than in the control group (P < 0.05). Urea, creatinine and CrCl values were not statistically different from the controls. One week after BMT, the level of cystatin C was significantly low as compared to the levels measured 24 h before BMT, but was still significantly higher than the controls (P < 0.05), whereas the levels of urea, creatinine and CrCl were in accordance with the levels of the controls. Two and three weeks after BMT, cystatin C values maintained the significant increase (P < 0.05), whereas the values of urea, creatinine and CrCl still corresponded with those of the controls in both group. Conclusions: Our preliminary data expose that cystatin C is not a reliable GFR marker in patients during leukemia or for monitoring nephrotoxic drugs used in BMT, but we can not reach definitive conclusion due to no gold standard for comparing the diagnostic accuracy of cystatin C. Further study is needed to elucidate the precise mechanism underlying this observation. © 2005 The Canadian Society of Clinical Chemists. All rights reserved

The effects of the positive end expiratory pressure during laparoscopic cholecystectomy on postoperative respiratory function: A randomized controlled trial

Aim. The aim of the present study was to investigate the effects of 8 cm H2O of positive end expiratory pressure (PEEP) with pneumoperitoneum (PP) of 14 mmHg on respiratory system mechanics and function in addition to oxygenation during and after laparoscopic cholecystectomy. Methods. In this prospective study, 70 ASA physical status I-II patients undergoing laparoscopic cholecystectomy were randomized equally to ventilate with 8 cm H2O of PEEP (Group 1) or 0 cm H2O of PEEP (Group 2) during PP. We determined tidal volume (VT), peak inspiratory pressure (PIP), mean airway pressure and dynamic pulmonary compliance (Cdyn) in the intraoperative period. Forced expiratory volume in the first second (FEV 1), forced vital capacity (FVC), peak expiratory flow (PEF), the relation of the FEV1 to the FVC (FEV1/ FVC) and forced expiratory flow in the midexpiratory phase (FEF25-75%) were determined by using spirometry before and two hours after surgery. Results. In Group 2, Cdyn was significantly lower compared to Group 1 at measurement times of C-14 and C-20 (P<0.05; P<0.01, respectively) but there was no significant difference after desufflation. The ratios of target FEV1 values at the second postoperative hour were 74.19% in Group 1 and 35.71% in Group 2 (χ2 test:7.35; P=0.0067). When the spirometry was repeated at the 24th postoperative hour for the patients that could not achieve target FEV1 values, it was determined that 77.41% of Group 1 and 53.57% of Group 2 (χ2 test:2.75; P=0.0975) achieved the target values. Conclusion. This study shows that the PEEP of 8 cmH2O in laparoscopic cholecystectomy improves postoperative respiratory function in addition to significant improvement in Cdyn during pneumoperitoneum

Weighing Diverse Theoretical Models on Turkish Maqam

Since the early 20th century, various theories have been advanced in order to mathematically explain and notate modes of Traditional Turkish music known as maqams. In this article, maqam scales according to various theoretical models based on different tunings are compared with pitch measurements obtained from select recordings of master Turkish performers in order to study their level of match with analysed data. Chosen recordings are subjected to a fully computerized sequence of signal processing algorithms for the automatic determination of the set of relative pitches for each maqam scale: f0 estimation, histogram computation, tonic detection + histogram alignment, and peak picking. For nine well-recognized maqams, automatically derived relative pitches are compared with scale tones defined by theoretical models using quantitative distance measures. We analyse and interpret histogram peaks based on these measures to find the theoretical models most conforming with all the recordings, and hence, with the quotidian performance trends influenced by them.TÜBİTA

biochemical analytes in Turkey using Abbott analyzers

Background: A nationwide multicenter study was organized to establish reference intervals (RIs) in the Turkish population for 25 commonly tested biochemical analytes and to explore sources of variation in reference values, including regionality.Methods: Blood samples were collected nationwide in 28 laboratories from the seven regions (>= 400 samples/region, 3066 in all). The sera were collectively analyzed in Uludag University in Bursa using Abbott reagents and analyzer. Reference materials were used for standardization of test results. After secondary exclusion using the latent abnormal values exclusion method, RIs were derived by a parametric method employing the modified Box-Cox formula and compared with the RIs by the non-parametric method. Three-level nested ANOVA was used to evaluate variations among sexes, ages and regions. Associations between test results and age, body mass index (BMI) and region were determined by multiple regression analysis (MRA).Results: By ANOVA, differences of reference values among seven regions were significant in none of the 25 analytes. Significant sex-related and age-related differences were observed for 10 and seven analytes, respectively. MRA revealed BMI-related changes in results for uric acid, glucose, triglycerides, high-density lipoprotein (HDL)-cholesterol, alanine aminotransferase, and.-glutamyltransferase. Their RIs were thus derived by applying stricter criteria excluding individuals with BMI >28 kg/m(2). Ranges of RIs by non-parametric method were wider than those by parametric method especially for those analytes affected by BMI.Conclusions: With the lack of regional differences and the well-standardized status of test results, the RIs derived from this nationwide study can be used for the entire Turkish population