181 research outputs found
Ownership Rights and Investment in Agricultural Land in Ghana: A Gender Analysis
This paper examines the relationship between ownership rights and investment in agricultural land from a gender perspective in Ghana, using the Two-Stage Conditional Maximum Likelihood estimation technique and data from the Ghana Household Asset Survey. The results indicate that investment in agricultural lands is generally low in Ghana and tends to occur mostly in agricultural lands owned by men suggesting its inability to enhance tenure security. Furthermore, investment in agricultural lands owned by men is associated with a wider range of ownership rights. However, the same cannot be said about agricultural land owned by women as investments in their land do not significantly improve their rights to the land. Except for economic rights that appear to have a significant negative association with investments in agricultural lands owned by women, all other rights have no significant relationship with investments in agricultural lands owned by both men and women. There is a positive relationship between age and ownership rights for men suggesting that the youth may have challenges securing their tenure. We recommend the strengthening of the current land administration projects to enhance tenure security. Policies that will support the growing of perennial trees, construction of farmhouses and irrigation should be put in place by the government to encourage men to undertake such investments as they tend to improve ownership rights of agricultural lands. More should also be done to secure the ownership rights of the youth if the government wants them to engage in agriculture
Seasonality of Primary productivity of phytoplankton of Lake Bosomtwe, Ghana -West Africa
The primary productivity and seasonality of phytoplankton and its seasonality in Lake Bosomtwe (Ghana), West Africa were studied from September 2005 to August 2006 using the dissolved oxygen method. The wet weight biomass (0.41±0.37 gCm-2d-1, n=25), Chlorophyll a (52.11±19.51 mg m-2, n=17), mixed layer depth (9.28±3.47 m, n=25), euphotic depth (4.43±1.76 m, n=25), ratio of mixed layer to euphotic depth (2.17±0.74, n=25), secchi disc depth (1.52±0.34 m, n=25), irradiance (1180±341.28 µE m-2s-1, n=25), extinction coefficient (0.97±0.46, n=25), and total phosphorus concentrations (1.84±0.49 µmol L-1, n=20) were measured to assess their influence on the productivity of the phytoplankton. Our assessment revealed high areal gross productivity of the phytoplankton (4.72 ± 1.56 gC m-2 d-1, n = 25) which is within the range for tropical African lakes, but concurrent high areal community respiration rates (4.34 ± 2.78 gC m-2 d-1, n = 25) contributed to a low net productivity (0.37 ± 2.32 gC m-2 d-1, n = 25) and growth rates (0.14 ± 0.33 d-1, n = 21). Variabilities in the gross productivity of the phytoplankton were high (CV =33.10 %) and driven by similarly high variabilities in the physicochemical and biological parameters. Productivity also exhibited clear seasonality associated with the mixing and stratification of the lake. The physicochemical and biological parameters (mixed layer depth, euphotic depth, secchi disc depth, irradiance, chlorophyll a, and the community respiration) all had a positive relationship with the primary production) whiles ratio of mixed layer to euphotic depth, total phosphorus, wet weigh biomass had a negative relationship with the gross productivity. Of all the measured parameters, only areal community respiration (r2 = 30.6 %) had a significant predictive value (r2 < 0.05).
The Relationship between Mixing and Stratification Regime on the Phytoplankton of Lake Bosomtwe (Ghana), West Africa
The seasonal changes in the phytoplankton community in terms of biomass composition and associated physicochemical parameters of the Lake Bosomtwe (Ghana) located in West Africa were studied between 2004 and 2006 to assess the mixing and stratification regime of the lake on the phytoplankton dynamics. From water samples obtained from a central index station, biomass composition was assessed by converting phytoplankton counts to wet weights-based approximation into cell volume values; whiles mixed layer and euphotic depths were analyzed using temperature and light profiles of the lake respectively. Total phosphorus was estimated using the Ascorbic Acid Method. Results from the dataset showed that the phytoplankton biomass was dominated by the Cyanophyceae throughout the study period despite the seasonal changes associated with the mixing and stratification regimes. There were significant inter-annual differences in the mean values of the euphotic depth and the wet weight biomass (P < 0.05). However differences in the mean values of the mixed layer depth, the ratio of the mixed layer depth:euphotic depth, and total phosphorus concentration (P > 0.05) were insignificant. High variations in the mixed layer depth (CV > 34 %) and the euphotic depth (CV > 32) drive similarly high variations in the wet weight biomass (CV > 28) as is the case for many stratifying tropical lakes. However, both were poor predictors of the phytoplankton wet weight biomass behaviour (mixed layer depth, r2 = 0.1034; euphotic depth, r
Mosquito Abundance, Bed net Coverage and Other Factors Associated with Variations in Sporozoite Infectivity Rates in Four Villages of Rural Tanzania.
Entomological surveys are of great importance in decision-making processes regarding malaria control strategies because they help to identify associations between vector abundance both species-specific ecology and disease intervention factors associated with malaria transmission. Sporozoite infectivity rates, mosquito host blood meal source, bed net coverage and mosquito abundance were assessed in this study. A longitudinal survey was conducted in four villages in two regions of Tanzania. Malaria vectors were sampled using the CDC light trap and pyrethrum spray catch methods. In each village, ten paired houses were selected for mosquitoes sampling. Sampling was done in fortnight case and study was undertaken for six months in both Kilimanjaro (Northern Tanzania) and Dodoma (Central Tanzania) regions. A total of 6,883 mosquitoes were collected including: 5,628 (81.8%) Anopheles arabiensis, 1,100 (15.9%) Culex quinquefasciatus, 89 (1.4%) Anopheles funestus, and 66 (0.9%) Anopheles gambiae s.s. Of the total mosquitoes collected 3,861 were captured by CDC light trap and 3,022 by the pyrethrum spray catch method. The overall light trap: spray catch ratio was 1.3:1. Mosquito densities per room were 96.5 and 75.5 for light trap and pyrethrum spray catch respectively. Mosquito infectivity rates between villages that have high proportion of bed net owners and those without bed nets was significant (P < 0.001) and there was a significant difference in sporozoite rates between households with and without bed nets in these four villages (P < 0.001). Malaria remains a major problem in the study areas characterized as low transmission sites. Further studies are required to establish the annual entomological inoculation rates and to observe the annual parasitaemia dynamics in these communities. Outdoor mosquitoes collection should also be considered
Systematic reviews of complementary therapies - an annotated bibliography. Part 1: Acupuncture
Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three major complementary therapies (acupuncture, herbal medicine, homeopathy). This article is dealing with acupuncture. Potentially relevant reviews were searched through the register of the Cochrane Complementary Medicine Field, the Cochrane Library, Medline, and bibliographies of articles and books. To be included articles had to review prospective clinical trials of acupuncture; had to describe review methods explicitly; had to be published; and had to focus on treatment effects. Information on conditions, interventions, methods, results and conclusions was extracted using a pretested form and summarized descriptively. Results From a total of 48 potentially relevant reviews preselected in a screeening process 39 met the inclusion criteria. 22 were on various pain syndromes or rheumatic diseases. Other topics addressed by more than one review were addiction, nausea, asthma and tinnitus. Almost unanimously the reviews state that acupuncture trials include too few patients. Often included trials are heterogeneous regarding patients, interventions and outcome measures, are considered to have insufficient quality and contradictory results. Convincing evidence is available only for postoperative nausea, for which acupuncture appears to be of benefit, and smoking cessation, where acupuncture is no more effective than sham acupuncture. Conclusions A large number of systematic reviews on acupuncture exists. What is most obvious from these reviews is the need for (the funding of) well-designed, larger clinical trials
Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
High grade gliomas are malignant brain tumors that arise in the central nervous system, in patients of all ages. Currently, the standard of care, entailing surgery and chemo radiation, exhibits a survival rate of 14-17 months. Thus, there is an urgent need to develop new therapeutic strategies for these malignant brain tumors. Currently, immunotherapies represent an appealing approach to treat malignant gliomas, as the pre-clinical data has been encouraging. However, the translation of the discoveries from the bench to the bedside has not been as successful as with other types of cancer, and no long-lasting clinical benefits have been observed for glioma patients treated with immune-mediated therapies so far. This review aims to discuss our current knowledge about gliomas, their molecular particularities and the impact on the tumor immune microenvironment. Also, we discuss several murine models used to study these therapies pre-clinically and how the model selection can impact the outcomes of the approaches to be tested. Finally, we present different immunotherapy strategies being employed in clinical trials for glioma and the newest developments intended to harness the immune system against these incurable brain tumors.Fil: Garcia Fabiani, Maria Belen. University of Michigan; Estados Unidos. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Haase, Santiago. University of Michigan; Estados Unidos. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Comba, Andrea. University of Michigan; Estados Unidos. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Carney, Stephen. University of Michigan; Estados UnidosFil: McClellan, Brandon. University of Michigan; Estados UnidosFil: Banerjee, Kaushik. University of Michigan; Estados UnidosFil: Alghamri, Mahmoud S.. University of Michigan; Estados UnidosFil: Syed, Faisal. University of Michigan; Estados UnidosFil: Kadiyala, Padma. University of Michigan; Estados UnidosFil: Nuñez, Felipe. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones BioquÃmicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones BioquÃmicas de Buenos Aires; ArgentinaFil: Candolfi, Marianela. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Asad, Antonela SofÃa. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: González, Nazareno. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Aikins, Marisa E.. University of Michigan; Estados UnidosFil: Schwendeman, Anna. University of Michigan; Estados UnidosFil: Moon, James J.. University of Michigan; Estados UnidosFil: Lowenstein, Pedro R.. University of Michigan; Estados UnidosFil: Castro, Maria G.. University of Michigan; Estados Unido
Chronic Diseases in North-West Tanzania and Southern Uganda. Public Perceptions of Terminologies, Aetiologies, Symptoms and Preferred Management
Research outputs produced to support a quantitative population survey, quantitative health facility survey, focus groups and in-depth interviews performed by the projec
Malaria prevention in north-eastern Tanzania: patterns of expenditure and determinants of demand at the household level
OBJECTIVE: This study aims to provide a better understanding of the amounts spent on different malaria prevention products and the determinants of these expenditures. METHODS: 1,601 households were interviewed about their expenditure on malaria mosquito nets in the past five years, net re-treatments in the past six months and other expenditures prevention in the past two weeks. Simple random sampling was used to select villages and streets while convenience sampling was used to select households. Expenditure was compared across bed nets, aerosols, coils, indoor spraying, using smoke, drinking herbs and cleaning outside environment. FINDINGS: 68% of households owned at least one bed net and 27% had treated their nets in the past six months. 29% were unable to afford a net. Every fortnight, households spent an average of US 0.21). Factors positively related to expenditure were household wealth, years of education of household head, household head being married and rainy season. Poor quality roads and living in a rural area had a negative impact on expenditure. CONCLUSION: Expenditure on bed nets and on alternative malaria prevention products was comparable. Poor households living in rural areas spend significantly less on all forms of malaria prevention compared to their richer counterparts. Breaking the cycle between malaria and poverty is one of the biggest challenges facing malaria control programmes in Africa
National Mass Drug Administration Costs for Lymphatic Filariasis Elimination
Lymphatic filariasis (LF), commonly known as elephantiasis, is a profoundly disfiguring parasitic disease caused by thread-like nematode worms. This disease can often be disabling, thus reducing the potential productivity of the affected individuals. The WHO places the number of people at risk in 83 countries at 1.307 billion. This study was undertaken in seven countries—Burkina Faso, Ghana, Egypt, Tanzania, the Philippines, the Dominican Republic, and Haiti—using a common protocol to determine the costs of mass drug administration (MDA) programs to interrupt transmission of infection with LF, because there is lack of sufficient information about the costs of these programs. The results demonstrate that LF MDA is affordable and relatively inexpensive when compared to other public health programs. In the context of initiatives for integrating programs for the control and elimination of neglected tropical diseases, this study adds specifically to the relatively scarce body of information about the costs of MDA programs for LF. It also adds to the general knowledge about the application of methods that can be used to estimate the costs and cost-effectiveness of an integrated approach
Differences in alcohol consumption and drinking patterns in Ghanaians in Europe and Africa: The RODAM Study
BACKGROUND: Little is known about alcohol consumption among Africans living in rural and urban Africa compared to African migrants in Europe. We compared the patterns of alcohol consumption in a group of Ghanaians living in different locations in Ghana and in Europe and examined the factors associated with drinking alcohol. METHODS: Data were from a cross-sectional study (RODAM) of Ghanaians aged 25-70 years living in rural and urban Ghana and in Amsterdam, Berlin and London. Information on how often participants consumed at least one standard alcoholic drink in the preceding 12 months, the type of alcoholic beverage and the average serving size was obtained using a food propensity questionnaire. The associations between drinking alcohol and socio-demographic variables, and frequency of attending religious services were investigated using logistic regression models stratified by site and sex. For Ghanaians living in Europe, the number of years since migration and acculturation were also included in the model as covariates. RESULTS: 4280 participants (62.2% women) were included in the analyses. In both men and women, the prevalence of drinking and amount of alcohol consumed per day was highest in Berlin (prevalence of drinking 71.0% and 61.7%) and lowest in urban Ghana (41.4% and 26.8%). After adjustment for age and education in both men and women in Europe, those attending religious services less frequently reported higher levels of drinking alcohol than non-attendants (never attend/no religion compared to attending service at least once a week men OR 4.60 95% CI 2.85, 7.44; women OR 1.80 95% CI 1.12, 2.90) p-trend with frequency <0.001 in men; 0.002 in women); this association was seen also in men in rural Ghana (p-trend = 0.001) and women in urban Ghana (p-trend = 0.02). The prevalence of drinking was positively associated with years since migration in both men and women in Europe ((OR per years increase in time lived in Europe 1.25 (95% CI 1.02,1.53) test for trend p = 0.03 in women; OR 1.29 (95% CI 1.03, 1.62 p = 0.03 in men) but no association was found with self-reported measures of acculturation (ethnic identity, cultural orientation or social networks). CONCLUSION: There are marked differences in alcohol consumption between Ghanaians living in Europe and in Ghana suggesting migration has an important influence of drinking patterns and also suggesting the possibility of requiring different strategies in alcohol reduction campaigns among Ghanaians in different locations
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