45,032 research outputs found
Numerical Modeling of Shock-Induced Damage for Granite under Dynamic Loading
Johnson-Holmquist constitutive model for brittle materials, coupled with a crack softening model, is used to describe the deviatoric and tensile crack propagation beneath impact crater in granite. Model constants are determined either directly from static uniaxial strain loading experiments, or indirectly from numerical adjustment. Constants are put into AUTODYN-2D from Century Dynamics to simulate the shock-induced damage in granite targets impacted by projectiles at different velocities. The agreement between experimental data and simulated results is encouraging. Instead of traditional grid-based methods, a Smooth Particle Hydrodynamics solver is used to define damaged regions in brittle media
Karhunen-Lo\`eve expansion for a generalization of Wiener bridge
We derive a Karhunen-Lo\`eve expansion of the Gauss process , , where is a
standard Wiener process and is a twice continuously
differentiable function with and . This
process is an important limit process in the theory of goodness-of-fit tests.
We formulate two special cases with the function
, , and , ,
respectively. The latter one corresponds to the Wiener bridge over from
to .Comment: 25 pages, 1 figure. The appendix is extende
Using the Xenopus Developmental Eye Regrowth Stystem to Distinguish the Role of Developmental Versus Regenerative Mechanisms
A longstanding challenge in regeneration biology is to understand the role of developmental mechanisms in restoring lost or damaged tissues and organs. As these body structures were built during embryogenesis, it is not surprising that a number of developmental mechanisms are also active during regeneration. However, it remains unclear whether developmental mechanisms act similarly or differently during regeneration as compared to development. Since regeneration is studied in the context of mature, differentiated tissues, it is difficult to evaluate comparative studies with developmental processes due to the latter’s highly proliferative environment. We have taken a more direct approach to study regeneration in a developmental context (regrowth). Xenopus laevis, the African clawed frog, is a well-established model for both embryology and regeneration studies, especially for the eye. Xenopus eye development is well-defined. Xenopus is also an established model for retinal and lens regeneration studies. Previously, we demonstrated that Xenopus tailbud embryo can successfully regrow a functional eye that is morphologically indistinguishable from an age-matched control eye. In this study, we assessed the temporal regulation of retinal differentiation and patterning restoration during eye regrowth. Our findings showed that during regrowth, cellular patterning and retinal layer formation was delayed by approximately 1 day but was restored by 3 days when compared to eye development. An assessment of the differentiation of ganglion cells, photoreceptor cells, and Müller glia indicated that the retinal birth order generated during regrowth was consistent with that observed for eye development. Thus, retina differentiation and patterning during regrowth is similar to endogenous eye development. We used this eye regrowth model to assess the role of known mechanisms in development versus regrowth. Loss-of-function studies showed that Pax6 was required for both eye development and regrowth whereas apoptosis was only required for regrowth. Together, these results revealed that the mechanisms required for both development and regrowth can be distinguished from regrowth-specific ones. Our study highlights this developmental model of eye regrowth as a robust platform to systematically and efficiently define the molecular mechanisms that are required for regeneration versus development
The Cultural Reconstruction of Taboo Under Mama Uluk’s Leadership in Kampong Dukuh, a Sundanese Traditional Hamlet in Garut Regency West Java Indonesia
 Kampung Dukuh yang terletak di Desa Ciroyom, Kecamatan Cikelet Kabupaten Garut merupa- kan salah satu kampung adat yang ada di Jawa Barat yang memiliki banyak keunikan. Pamali sebagai salah satu sistem pengetahuan masyarakat adat Sunda. Pamali masih dipertahankan dalam kebu- dayaan masyarakat adat Kampung Dukuh. Walaupun tidak ada resiko yang tertulis ketika melaku- kan hal yang melanggar pamali, namun masyarakat kampung adat masih merasa takut durhaka atau dosa jika pamali tidak dilaksanakan dalam keseharian hidupnya. Sekaitan dengan hal ini, penelitian ini bertujuan menggambarkan berbagai larangan atau pamali yang telah direkonstruksi di masa kepemimpinan Mama Uluk di kampung Adat Dukuh Kabupaten Garut. Penelitian ini mengguna- kan metode kualitatif dengan teknik pengumpulan data wawancara dan pengamatan langsung. Hasil penelitian ini menjelaskan cara penyampaian larangan pada waktu yang telah ditentukan dan jenis larangan atau pamali atau pamali yang dipelihara dan terus diwariskankan secara turun temurun sampai saat ini dalam kehidupan sehari-hari seperti larangan di Makom Syech Jalil, Hutan Lindung dan bagaimana ketua adat (mama uluk) dalam kepemimpinannya merekonstruksi budaya tersebut dalam kehidupan keseharian mereka di kampung Dukuh kabupaten Garut.
Modeling pedestrian evacuation movement in a swaying ship
With the advance in living standard, cruise travel has been rapidly expanding
around the world in recent years. The transportation of passengers in water has
also made a rapid development. It is expected that ships will be more and more
widely used. Unfortunately, ship disasters occurred in these years caused
serious losses. It raised the concern on effectiveness of passenger evacuation
on ships. The present study thus focuses on pedestrian evacuation features on
ships. On ships, passenger movements are affected by the periodical water
motion and thus are quite different from the characteristic when walking on
static horizontal floor. Taking into consideration of this special feature, an
agent-based pedestrian model is formulized and the effect of ship swaying on
pedestrian evacuation efficiency is investigated. Results indicated that the
proposed model can be used to quantify the special evacuation process on ships.Comment: Traffic and Granular Flow'15, At Delft, the Netherland
On the Stability and Structural Dynamics of Metal Nanowires
This article presents a brief review of the nanoscale free-electron model,
which provides a continuum description of metal nanostructures. It is argued
that surface and quantum-size effects are the two dominant factors in the
energetics of metal nanowires, and that much of the phenomenology of nanowire
stability and structural dynamics can be understood based on the interplay of
these two competing factors. A linear stability analysis reveals that metal
nanocylinders with certain magic conductance values G=1, 3, 6, 12, 17, 23, 34,
42, 51, 67, 78, 96, ... times the conductance quantum are exceptionally stable.
A nonlinear dynamical simulation of nanowire structural evolution reveals a
universal equilibrium shape consisting of a magic cylinder suspended between
unduloidal contacts. The lifetimes of these metastable structures are also
computed.Comment: 8 pages, 6 figure
Deactivation of gold(I) catalysts in the presence of thiols and amines – characterisation and catalysis
Constructing solutions to the Bj\"orling problem for isothermic surfaces by structure preserving discretization
In this article, we study an analog of the Bj\"orling problem for isothermic
surfaces (that are more general than minimal surfaces): given a real analytic
curve in , and two analytic non-vanishing orthogonal
vector fields and along , find an isothermic surface that is
tangent to and that has and as principal directions of
curvature. We prove that solutions to that problem can be obtained by
constructing a family of discrete isothermic surfaces (in the sense of Bobenko
and Pinkall) from data that is sampled along , and passing to the limit
of vanishing mesh size. The proof relies on a rephrasing of the
Gauss-Codazzi-system as analytic Cauchy problem and an in-depth-analysis of its
discretization which is induced from the geometry of discrete isothermic
surfaces. The discrete-to-continuous limit is carried out for the Christoffel
and the Darboux transformations as well.Comment: 29 pages, some figure
Comment on Bress et al. Effect of Intensive Versus Standard Blood Pressure Treatment According to Baseline Prediabetes Status: A Post Hoc Analysis of a Randomized Trial. Diabetes Care 2017;40:1401-1408.
info:eu-repo/semantics/publishedVersio
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