Bifidobacterium infantis strains with and without a combination of Oligofructose and Inulin (OFI) attenuate inflammation in DSS-induced colitis in rats

BACKGROUND: Pathogenesis of inflammatory bowel disease is thought to be through different factors and there is a relationship between the gut flora and the risk of its development. Probiotics can manipulate the microflora in chronic inflammation and may be effective in treating inflammation. Bifidobacterium are saccharolytic and their growth in the gut can be promoted by non-absorbable carbohydrates and its increase in the colon appears to be of benefit. METHODS: Oligofructose and inulin (OFI) alone and the two B. infantis DSM 15158 and DSM 15159 with and without OFI, were fed to Sprague-Dawley rats for 7 days prior to colitis induction and administrations continued for another 7 days with the DSS. Colitis severity assessed using a Disease Activity Index. Samples were collected 7 days after colitis induction, for intestinal bacterial flora, bacterial translocation, short chain fatty acids (SCFAs), myeloperoxidase (MPO), cytokines (IL-1β, TNF-α, IL-10 and TGF-β) and malondialdehyde (MDA). RESULTS: OFI alone or the B. infantis strains with and without OFI improved significantly the DAI and decreased colonic MPO activity. Colonic tissue IL-1β decreased significantly in all treated groups except B. infantis DSM 15158. MDA decreased significantly in B. infantis DSM 15159 with and without OFI compared to colitis control. Succinic acid increased significantly in OFI group with and without DSM 15159 compared to all groups. Sum values of propionic, succinic acid and butyric acid increased significantly in all groups compare to the colitis control. Bacterial translocation to mesenteric lymph nodes decreased significantly in all groups compared to colitis control. Translocation to the liver decreased significantly in all groups compare to the colitis control and OFI + B. infantis DSM 15158 groups. CONCLUSION: Administrations of OFI and Bifidobacterium improve DSS-induced acute colitis and have an anti-inflammatory effect. Major differences in effect were observed between the two B. infantis strains as indicated in MDA and succinic acid concentration as well as bacterial translocation rate in synbiotic combinations

Klasstrukturen i Sverige 1980

The purpose of the survey is to describe and measure the Swedish class structure regarding mobility, political activity, attitudes and consciousness. A battery of questions addressed work-related issues such as supervision, decision-making, autonomy, respondents formal position in the hierarchy, ownership, credentials, and income. Other work-related data describe the size, industrial sector, and government or corporate linkage of the individuals employer. Further information was gathered on the class origins of the respondents family and of the families of the respondents spouse and friends. Data on class-related experiences such as unemployment and union participation were also collected, as well as data on the division of power and labour in the household. In addition the survey contained a broad range of questions on social and political attitudes and the respondents political participation. The study is part of the multinational study ´Class Structure and Class Consciousness´ (ICPSR 8413), which includes almost identificial studies from United States, Norway, Canada, and Finland.The purpose of the survey is to describe and measure the Swedish class structure regarding mobility, political activity, attitudes and consciousness. A battery of questions addressed work-related issues such as supervision, decision-making, autonomy, respondents formal position in the hierarchy, ownership, credentials, and income. Other work-related data describe the size, industrial sector, and government or corporate linkage of the individuals employer. Further information was gathered on the class origins of the respondents family and of the families of the respondents spouse and friends. Data on class-related experiences such as unemployment and union participation were also collected, as well as data on the division of power and labour in the household. In addition the survey contained a broad range of questions on social and political attitudes and the respondents political participation. The study is part of the multinational study ´Class Structure and Class Consciousness´ (ICPSR 8413), which includes almost identificial studies from United States, Norway, Canada, and Finland

Hemmet, barnen och makten 1996_2

SIFO survey study from 1996 with questions about economy and household work as a comparison between sexes. One data set for females and one for males.Enkätundersökning utförd av SIFO år 1996 med syfte att identifiera könsskillnader i relation till hushållssysslor och ekonomi. Uppdelat på ett dataset för varje kön

Delvis människa, delvis organisation

Partly human, partly organization In this article the phenomenon of organization is discussed and its consequences for the understanding of human actions and human choices are examined. Affiliation to organizations are found to be both restrictions on and preconditions for most human action. In this connection families are regarded as organizations as well as enterprises, voluntary associations and states. Human action is primarily action on behalf of organizations where individuals are partly human, partly organization. To understand the meaning of action on behalf of organization it is important to realize that people rarely choose their organizational affiliation. People are selected. This means that actions on behalf of organizations cannot be regarded as expressions of individual choices. Actions on behalf of organizations are generally characterized by a dual involvement.Sociologisk Forsknings digitala arkiv</p

Hemmet, barnen och makten 1996

SIFO survey study from 1996 with questions about economy and household work as a comparison between sexes. One data set for females and one for males.Enkätundersökning utförd av SIFO år 1996 med syfte att identifiera könsskillnader i relation till hushållssysslor och ekonomi. Uppdelat på ett dataset för varje kön

Delvis människa, delvis organisation

Partly human, partly organization In this article the phenomenon of organization is discussed and its consequences for the understanding of human actions and human choices are examined. Affiliation to organizations are found to be both restrictions on and preconditions for most human action. In this connection families are regarded as organizations as well as enterprises, voluntary associations and states. Human action is primarily action on behalf of organizations where individuals are partly human, partly organization. To understand the meaning of action on behalf of organization it is important to realize that people rarely choose their organizational affiliation. People are selected. This means that actions on behalf of organizations cannot be regarded as expressions of individual choices. Actions on behalf of organizations are generally characterized by a dual involvement.Sociologisk Forsknings digitala arkiv</p

Delvis människa, delvis organisation

Partly human, partly organization In this article the phenomenon of organization is discussed and its consequences for the understanding of human actions and human choices are examined. Affiliation to organizations are found to be both restrictions on and preconditions for most human action. In this connection families are regarded as organizations as well as enterprises, voluntary associations and states. Human action is primarily action on behalf of organizations where individuals are partly human, partly organization. To understand the meaning of action on behalf of organization it is important to realize that people rarely choose their organizational affiliation. People are selected. This means that actions on behalf of organizations cannot be regarded as expressions of individual choices. Actions on behalf of organizations are generally characterized by a dual involvement.Sociologisk Forsknings digitala arkiv</p

Upptäckten av det globala

Sociologisk Forsknings digitala arkiv</p

Vad hände på åttiotalet?

Sociologisk Forsknings digitala arkiv</p