26 research outputs found
Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry
- Author
- Abban D. W.
- Abdul N.
- Abud A. M.
- Adams F.
- Addala S.
- Adragao P.
- Ageno W.
- Aggarwal R.
- Agosti S.
- Agostoni P.
- Aguilar F.
- Aguinaga L.
- Ahmed J.
- Aiello A.
- Ainsworth P.
- Aiub J. R.
- Al-Dallow R.
- Alderson L.
- Alexopoulos D.
- Aliyar P.
- Almeida L. F.
- Alonso D.
- Alvaro F.
- Amado J.
- Amara W.
- Amelot M.
- Amjadi N.
- Ammirati F.
- Andrade M.
- Andrawis N.
- Andres H.
- Annoni G.
- Ansalone G.
- Antero C.
- Ariani M. K.
- Arias J. C.
- Armero S.
- Arora C.
- Asensi J. O.
- Aslam M. S.
- Asselman M.
- Audouin P.
- Augenbraun C.
- Ayala C.
- Aydin S.
- Aydin S.
- Ayryanova I.
- Aziz E.
- Backes L. M.
- Badings E.
- Bagni E.
- Baker S. H.
- Bala R.
- Baldicortada A. J. B.
- Banerjeebrunschwig S. C.
- Bank A.
- Barrbullinga C. J.
- Bartlettcabrera M. J. W.
- Basic KesCaccavo V. A.
- Baulacai G. S.
- Behrenscaine S. S.
- Bellcalo A. L.
- Benedetti R.
- Benhalimacandeias B. R.
- Berg J. M.
- Bergler-Klein J.
- Berneaucapucci J. -B. A.
- Bernsteincaputo R. A. R.
- Berrospirizo P. T. C.
- Berti S.
- Best E.
- Bettencourtcarolei P. A.
- Betzucarreno R. S.
- Bhagwatcarvalho R. P.
- Bhatta L.
- Biscionecasu F. G.
- Bisignani C.
- Bisignani G.
- Blackcayla T. G.
- Blochcelentano M. J. A.
- Bloom S.
- Blumberg E.
- Bo M
- Bodes R. S.
- Bohmer E.
- Bollmann A.
- Bongiorni M. G.
- Boriani G.
- Bott J.
- Bottacchi E.
- Bradman D.
- Brautigam D.
- Breton N.
- Briones I. R.
- Brkljacic D. D.
- Brouwers P. J. A. M.
- Browne K.
- Bruni S. B. A.
- Buathier H.
- Buenostro G. C.
- Buhl A.
- C. -S. Ma
- Calvi V.
- Campos R. N.
- Capuano V.
- Cardona F.
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- Cheema A.
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- Chumakova G.
- Cislowski D. J.
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- Coodley G.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry
- Author
- Abban D. W.
- Abdul N.
- Abud A. M.
- Adams F.
- Addala S.
- Adragao P.
- Ageno W.
- Aggarwal R.
- Agosti S.
- Agostoni P.
- Aguilar F.
- Aguinaga L.
- Ahmed J.
- Aiello A.
- Ainsworth P.
- Aiub J. R.
- Al-Dallow R.
- Alderson L.
- Alexopoulos D.
- Aliyar P.
- Almeida L. F.
- Alonso D.
- Alvaro F.
- Amado J.
- Amara W.
- Amelot M.
- Amjadi N.
- Ammirati F.
- Andrade M.
- Andrawis N.
- Annoni G.
- Ansalone G.
- Ariani M. K.
- Arias J. C.
- Armero S.
- Arora C.
- Asensi J. O.
- Aslam M. S.
- Asselman M.
- Audouin P.
- Augenbraun C.
- Ayala C. A. C.
- Aydin S.
- Aydin S.
- Ayryanova I.
- Aziz E.
- Backes L. M.
- Badings E.
- Bagni E.
- Baker S. H.
- Bala R.
- Baldi A.
- Bando S.
- Banerjee S.
- Bank A.
- Barr C.
- Bartlett M.
- Basic Kes V.
- Baula G.
- Behrens S.
- Bell A.
- Benedetti R.
- Benhalima B.
- Berg J. M.
- Bergler-Klein J.
- Berneau J. -B.
- Bernstein R. A.
- Berrospi P.
- Berti S.
- Berz A.
- Best E.
- Bettencourt P.
- Betzu R.
- Bhagwat R.
- Bhatta L.
- Biscione F.
- Bisignani G.
- Black T.
- Bloch M. J.
- Bloom S.
- Blumberg E.
- Bo M.
- Bodes R. S.
- Bohmer E.
- Bollmann A.
- Bongiorni M. G.
- Boriani G.
- Boswijk D. J.
- Bott J.
- Bottacchi E.
- Bradman D.
- Brautigam D.
- Breton N.
- Briones I. R.
- Brkljacic D. D.
- Brouwers P. J. A. M.
- Browne K.
- Bruni A.
- Brunschwig C.
- Buathier H.
- Buenostro G. C.
- Buhl A.
- Bullinga J.
- Cabrera J. W.
- Caccavo A.
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- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background and purpose: Prospectively collected data comparing the safety and effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective was to directly compare the effectiveness and safety of NOACs in patients with newly diagnosed atrial fibrillation (AF). Methods: In GLORIA-AF, a large, prospective, global registry program, consecutive patients with newly diagnosed AF were followed for 3 years. The comparative analyses for (1) dabigatran vs rivaroxaban or apixaban and (2) rivaroxaban vs apixaban were performed on propensity score (PS)-matched patient sets. Proportional hazards regression was used to estimate hazard ratios (HRs) for outcomes of interest. Results: The GLORIA-AF Phase III registry enrolled 21,300 patients between January 2014 and December 2016. Of these, 3839 were prescribed dabigatran, 4015 rivaroxaban and 4505 apixaban, with median ages of 71.0, 71.0, and 73.0 years, respectively. In the PS-matched set, the adjusted HRs and 95% confidence intervals (CIs) for dabigatran vs rivaroxaban were, for stroke: 1.27 (0.79–2.03), major bleeding 0.59 (0.40–0.88), myocardial infarction 0.68 (0.40–1.16), and all-cause death 0.86 (0.67–1.10). For the comparison of dabigatran vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 1.16 (0.76–1.78), myocardial infarction 0.84 (0.48–1.46), major bleeding 0.98 (0.63–1.52) and all-cause death 1.01 (0.79–1.29). For the comparison of rivaroxaban vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 0.78 (0.52–1.19), myocardial infarction 0.96 (0.63–1.45), major bleeding 1.54 (1.14–2.08), and all-cause death 0.97 (0.80–1.19). Conclusions: Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death. Registration: URL: https://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007. Date of registration: September 2013
Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation. the GLORIA-AF registry
- Author
- Abban D. W.
- Abdul N.
- Abud A. M.
- Adams F.
- Addala S.
- Adragao P.
- Ageno W.
- Aggarwal R.
- Agosti S.
- Agostoni P.
- Aguilar F.
- Aguinaga L.
- Ahmed J.
- Aiello A.
- Ainsworth P.
- Aiub J. R.
- Al-Dallow R.
- Alderson L.
- Aldrete Velasco J. A.
- Alexopoulos D.
- Aliyar P.
- Almeida L. F.
- Alonso D.
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- Amado J.
- Amara W.
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- Andrade M.
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- Angela Koh S. M.
- Anna omaszuk-Kazberuk
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- Ansalone G.
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- Zukerman L. S.
- Publication venue
- Hellenic Society of Cardiology. Publishing services by Elsevier B.V.
- Publication date
- 01/01/2021
- Field of study
Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
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- Aimoniotou-Georgiou E
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- Al-Soudaine Y
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- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial
- Author
- A Hirano
- A Jong
- Adrienne K Chan
- AE Brouwer
- AG Leite
- Ahmed Rizal Ganiem
- AI Hoepelman
- AL Buchman
- Alastair Gray
- Anatoli Kamali
- BJ Park
- CD Mathers
- CM van der Horst
- D Annane
- D Eric Searls
- Darma Imran
- David Dance
- David G Lalloo
- Eugene Ruzagira
- FE Coenjaerts
- Freddie Kibengo
- GA Syrogiannopoulos
- GE Thwaites
- Guy Thwaites
- Heiman Wertheim
- J de Gans
- J Kalita
- JD Heiss
- Jeremy Day
- Jeremy Farrar
- JN Day
- JN Day
- Joep J van Oosterhout
- JR Graybill
- JR Perfect
- Justin Beardsley
- JW Engstrom
- L Ostrosky-Zeichner
- Lan Phuong
- Laura Merson
- LJ Haddow
- Loc Truong Tho
- M Lane
- M Scarborough
- M van der Flier
- Marcel Wolbers
- Mayfong Mayxay
- MG Tauber
- ML Rodrigues
- N van Bruggen
- Natriana Tjahjani
- Ngo Thi Kim Cuc
- Nguyen Van Kinh
- Nguyen Van Vinh Chau
- Nick Day
- NJ Scolding
- O Lortholary
- O Lortholary
- Paul Newton
- PD Cremer
- Pham Thanh Thuy
- Q Zhou
- RA Seaton
- Rattanaphone Phetsouvanh
- Retno Wahyuningsih
- Robert Heyderman
- Robiatul Adawiyah
- S Kubo
- Sayaphet Rattanavong
- T Bicanic
- TC Ryken
- TH Nguyen
- Tran Quang Binh
- Tran Thi Hong Chau
- Tran Tinh Hien
- Wirongrong Chierakul
- World Health Organization
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Prevalence of alcohol consumption and related factors among students of higher education centers in one of the northeastern cities of Iran
- Author
- Abu-Ras W Ahmed S, Arfken CL
- Balsa AI Giuliano LM, French MT
- Bendtsen P Karlsson N, Dalal K, et al.
- Bewick BM Mulhern B, Barkham M, et al.
- Brandão YST Correia DS, de Farias MSJA, et al.
- Casswell S Thamarangsi T
- Davoren MP Cronin M, Perry IJ, et al.
- Ghandour LA Mouhanna F, Yasmine R, et al.
- Hayatbakhsh MR Najman JM, Bor W, et al.
- Kim JH Chan KW, Chow JK, et al.
- Murphy JG Hoyme CK, Colby SM, et al.
- Newbury-Birch D White M, Kamali F
- Prabhu A Obi KO, Rubenstein JH
- Ruisoto P Cacho R, López-Goñi JJ, et al.
- Salaspuro V Salaspuro M
- Sanchez-Ramirez DC Franklin R, Voaklander D
- Schulte MT Ramo D, Brown SA
- Slutske WS
- Wilsnack RW Wilsnack SC, Kristjanson AF, et al.
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2019
- Field of study
Islamic Mutual Funds as Faith-Based Funds in a Socially Responsible Context
- Author
- A J Gregory
- Avanzi Sri Research
- B Grossman
- C A Mallin
- C Cooper
- C Cowton
- D A Dickey
- D Baldwin
- Dow Jones
- Dow Jones
- E Girard
- F S Valpey
- Failaka
- Federica Miglietta
- Ftse
- Gianfranco Forte
- I Nyazee
- J M Samuels
- K A Hussein
- K T Benson
- Karim
- Karim
- M
- M Al-Amine
- M Bakar
- M Blair
- M Elgari
- M Friedman
- M H Kamali
- M N Fadeel
- M Orlitzky
- M Smyth
- M Usmani
- N Saleh
- P Mills
- P Moore
- R Bauer
- R Engle
- R J Luther
- R Sparkes
- R Sparkes
- R Taylor
- R Wilson
- R Wilson
- S Abbasi
- S Archer
- S Cox
- S Elefakhani
- S H Hamilton
- S Hakim
- S Hellsten
- S Johansen
- S Johansen
- S Naughton
- S T Husain
- T E Ahmed
- T W Dunfee
- T Y Delorenzo
- U M Chapra
- U M Chapra
- W F Sharpe
- Y Maroun
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2007
- Field of study
Sustainable reuse of dredged sediments as pavement materials by cement and fly ash stabilization
- Author
- A Ahmed
- A Ardah
- A Gupta
- A Kampala
- A Kampala
- AA Agapitus
- AA Al-Homidy
- AASHTO
- AASHTO
- Austroads
- C Suksiripattanapong
- C-S Shon
- CS Tang
- CY Yin
- D Dermatas
- D Wang
- D Wang
- DD Tomasevic
- E Silitonga
- EO Tastan
- F Yilmaz
- H Güllü
- H Güllü
- H Wen
- J Li
- KJ Osinubi
- L Wang
- M Abu-farsakh
- MP Bilondi
- N Yoobanpot
- NJ Jiang
- P Jamsawang
- P Jongpradist
- P Scanferla
- P Solanki
- P Voottipruex
- RB Kogbara
- S Arora
- S Horpibulsuk
- S Horpibulsuk
- S Horpibulsuk
- S Horpibulsuk
- S Kamali
- S Tripathy
- SM Shaheen
- SS Razouki
- SS Razouki
- V Dubois
- X Kang
- Z Tongwei
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
RECENT TRENDS IN THE CHEMISTRY OF THIENOPYRIDAZINES
- Author
- Abarca B.
- Abd El-Aal M. Gaber
- Adel M. Kamal El-Dean
- Ahmed S. N. Al-Kamali
- Alvarez-Sarande's R.
- Andersen H. S.
- Arnould J. C.
- Bantick J.
- Boigegrain R.
- Boigegrain R.
- Dal Piaz V.
- Dal Piaz V.
- Dal Piaz V.
- Dumas J. P.
- El-Abadelah M. M.
- Elnagdi M. H.
- Elnagdi M. H.
- Elnagdi M. H.
- Fischer U.
- Hassan A. Eyada
- Iwase N.
- Johnson R. E.
- Kamal El-Dean A. M.
- Leusen A. M. V.
- Mohamed S. A. El-Gaby
- Mohareb R. M.
- Moody C. J.
- New J. S.
- New J. S.
- Poole A. J.
- Press J. B.
- Profft E.
- Radwan Sh. M.
- Radwan Sh. M.
- Robba M. F.
- Robba M. F.
- Robba M. F.
- Robba M. F.
- Robba M. F.
- Robba M. F.
- Robev S.
- Sato E.
- Stone K. J.
- Talma A. G.
- Vartanyan R. S.
- Yamaguchi M.
- Yang S.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Natural convection and melting of NEPCM in a corrugated cavity under the effect of magnetic field
- Author
- A Al-Rashed
- A Brent
- A Hasan
- AE Kabeel
- AJ Chamkha
- B Ghasemi
- B Pekmen
- BS Yilbas
- C Ho
- CJ Smith
- F Selimefendigil
- F Selimefendigil
- F Selimefendigil
- Fatih Selimefendigil
- G Kefayati
- H Brinkman
- H Oztop
- Hakan F. Öztop
- HF Oztop
- I Jmal
- I Nkurikiyimfura
- I Sarris
- J Park
- J Reddy
- K Kant
- KA Mohammed
- KAR Ismail
- M Ahmed
- M Ghalambaz
- M Gharebaghi
- M Hamad
- M Hatami
- M Huang
- M Mumtaz
- M Piratheepan
- M Pirmohammadi
- M Rahman
- M Sheikholeslami
- M Sheikholeslami
- M Sheikholeslami
- N Rudraiah
- NS Bondareva
- NS Bondareva
- O Zienkiewicz
- P Biwole
- PVSS Srivatsa
- Q Xue
- R Al-Sayegh
- R Kamali
- R Nasrin
- S Murshed
- S Sarkar
- SH Hussain
- T Kousksou
- V Voller
- VL Brano
- W Lin
- X Jin
- Y Feng
- Y Pahamli
- ZS Kareem
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study