Pendekatan Pragmatik dalam Meningkatkan Keterampilan Berbicara pada Mata Pelajaran Bahasa Indonesia di Sekolah Dasar

This study aimed to describe the steps that need to be done in using a pragmatic approach to learning speaking skills in the sixth grade in elementary Negri 16 Sengah Temila districts. Hedgehog province of West Kalimantan. The method used is Naturalistic research because research is done in natural conditions. The sample was 49 students. Results of analysis addressing that mastery learning students only reach 57%. This leads to student learning outcomes by applying a pragmatic approach in an effort to increase mastery learning classical. While the students\u27 motivation is high with an average score is 65.9%

KARAKTERISTIK MONYET EKOR PANJANG (Macaca fascicularis) BERDASARKAN TINGKAT UMUR DI TAHURA POCUT MEURAH INTAN

Monyet Ekor Panjang (Macaca fascicularis) memiliki peran penting dalam kehidupan di alam. Habitat Monyet Ekor Panjang (Macaca fascicularis) dapat menjalankan fungsi ekologisnya, yaitu sebagai penyemaian atau menyemaikan benih, menumbuhkan biji menjadi benih untuk dipindah ke tempat penanaman. Kawasan Tahura memiliki keindahan alam yang begitu indah  juga memiliki beraekaragam jenis flora dan fauna didalamnya, selain dijadikan tempat wisata, Tahura  juga dimanfaatkan sebagai tempat konservasi, penelitian, praktikum lapangan dan kegiatan pembelajaran lapangan untuk siswa, mahasiswa maupun pemerhati lingkungan. Kawasan Tahura sudah mengalami alih fungsi lahan dan pembukaan lahan perkebunan baru pada kawasan tersebut. Penelitian ini bertujuan untuk mengetahui karakteristik Macaca fascicularis berdasarkan tingkat umur. Penelitian ini dilakukan dengan menggunakan metode survey eksploratif  yaitu melakukan penjelajahan atau pengamatan secara langsung pada lokasi pengamatan. Hasil penelitian dijumpai bahwa karakteristik Monyet Ekor Panjang (Macaca fascicularis) berdasarkan umur terbagi 5 kelompok yaitu Bayi, Anakan, Remaja, Betina dewasa dan Jantan Dewasa

Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4

© 2016. Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs in tonsil and normal adjacent tissues. With this dataset, we identified a list of microRNA (miRNA) which were highly over represented in tonsil cancers and showed that several miRNAs were able to regulate the tumour suppressor PDCD4 in a temporal manner. The dataset has been deposited into Gene Expression Omnibus (GSE75630)

DESAIN DAN IMPLEMENTASI ALAT PEMOTONG PAPAN BERBASIS CAD/CAM

ABSTRAKSI: Dalam dunia industri peranan alat yang dapat bekerja secara otomatis sangat di butuhkan, salah satunya adalah alat pemotong papan otomatis. Alat ini diharapkan dapat bekerja secara otomatis dan dapat menghasilkan potongan yang presisi sesuai dengan sketsa yang dibuat.Dalam proyek akhir ini direalisasikan suatu alat yang nantinya dapat digunakan untuk memotong papan secara otomatis dan presisi sesuai ukuran yang diinginkan. Alat ini dapat memotong papan secara otomatis sesuai dengan sketsa gambar yang telah dibuat di dalam computer. Pada alat ini digunakan software autoCAD sebagai media untuk menggambar sketsa yang diinginkan, kemudian file yang dihasilkan dari software autoCAD tersebut selanjutnya akan di proses kembali ke dalam software CAM untuk mendapatkan output berupa file teks G-code yang digunakan untuk pemrograman ke dalam bahasa mesin, kemudian selanjutnya digunakan sebuah rangkaian mikrokontroller sebagai pengolah data dari bahasa computer ke dalam bahasa mesin yang dihubungkan oleh sebuah port printer sebagai output dari computer yang digunakan untuk menggerakkan motor listrik (stepper motor). Sedangkan untuk pemotongnya, alat ini menggunakan mata bor khusus jenis endmill sebagai alat pemotongnya dan beberapa motor stepper sebagai alat penggeraknya yang telah disusun sedemikian rupa sehingga dimungkinkan akan dapat memotong papan secara omatis dan presisi sesuai sketsa yang telah dibuat.Dengan demikian diharapkan alat ini dapat membantu dalam proses produksi sehingga dapat meningkatkan hasil produksi secara signifikan jika dibandingkan dengan menggunakan alat pemotong secara manual.Kata Kunci : autoCAD,CAM, mikrokontroller, stepper motor, otomatis, presisi, port printer.ABSTRACT: In the world of the role of industry tools that can work automatically so in need, one of which is automatic board cutting tools. These devices are expected to work automatically and can generate a precision piece in accordance with the sketches are made.In this final project realized a tool that can later be used to cut the board automatically and the precision of the desired size. This tool can cut the board automatically according to the sketch drawings that have been made in the computer. In autoCAD software tool is used as a medium for sketching desired, then the resulting file from autoCAD software will then be processed back into the CAM software to get the output from the G-code text file that is used for programming into the machine language, then then used a microcontroller circuit as a data processor of the computer language into machine language that is connected by a printer port as the output of the computer used to drive an electric motor (stepper motor). As for the cutter, the tool uses a special type of drill bit as a tool endmill cutter and a stepper motor as a driving tool which has been compiled in such a way that is possible will be able to cut the board in omatis and precision according to the sketch that has been made.It is expected that these tools can assist in the production process so as to increase production significantly when compared to using a cutting tool manually.Keyword: autoCAD, CAM, microcontroller, stepper motor, automatic, precision, printer port

Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes

Long non-coding RNAs (lncRNAs) form the largest transcript class in the human transcriptome. These lncRNA are expressed not only in the cells, but they are also present in the cell-derived extracellular vesicles such as exosomes. The function of these lncRNAs in cancer biology is not entirely clear, but they appear to be modulators of gene expression. In this study, we characterize the expression of lncRNAs in several prostate cancer exosomes and their parental cell lines. We show that certain lncRNAs are enriched in cancer exosomes with the overall expression signatures varying across cell lines. These exosomal lncRNAs are themselves enriched for miRNA seeds with a preference for let-7 family members as well as miR-17, miR-18a, miR-20a, miR-93 and miR-106b. The enrichment of miRNA seed regions in exosomal lncRNAs is matched with a concomitant high expression of the same miRNA. In addition, the exosomal lncRNAs also showed an over representation of RNA binding protein binding motifs. The two most common motifs belonged to ELAVL1 and RBMX. Given the enrichment of miRNA and RBP sites on exosomal lncRNAs, their interplay may suggest a possible function in prostate cancer carcinogenesis

Eustatic change modulates exhumation in the Japanese Alps

The exhumation of bedrock is controlled by the interplay between tectonics, surface processes, and climate. The highest exhumation rates of centimeters per year are recorded in zones of highly active tectonic convergence such as the Southern Alps of New Zealand or the Himalayan syntaxes, where high rock uplift rates combine with very active surface processes. Using a combination of different thermochronometric systems including trapped-charge thermochronometry, we show that such rates also occur in the Hida Mountain Range, Japanese Alps. Our results imply that centimeter per year rates of exhumation are more common than previously thought. Our thermochronometry data allow the development of time series of exhumation rate changes at the time scale of glacial-interglacial cycles, which show a fourfold increase in baseline rates to rates of ~10 mm/yr within the past ~65 k.y. This increase in exhumation rate is likely explained by knickpoint propagation due to a combination of very high precipitation rates, climatic change, sea-level fall, range-front faulting, and moderate rock uplift. Our data resolve centimeter-scale sub-Quaternary exhumation rate changes, which show that in regions with horizontal convergence, coupling between climate, surface processes, and tectonics can exert a significant and rapid effect on rates of exhumatio

Association of dietary patterns with continuous metabolic syndrome in children and adolescents; A nationwide propensity score-matched analysis: The CASPIAN-V study

Objective: This study aims to determine the association of dietary patterns with metabolic syndrome (MetS) and its components in children and adolescents. Methods: This nationwide study was conducted in 2015 among 4200 students aged 7-18 years, who lived in 30 provinces in Iran. The analysis was conducted based on the propensity score using a matched case-control study design. Three dietary patterns were obtained conducting a principal component analysis with a varimax rotation on 16 dietary groups. Continuous MetS score was computed by standardizing the residuals (z-scores) of MetS components by regressing them according to age and sex. The gold standard diagnosis of MetS was considered based on the International Diabetes Federation criteria. Moreover, for the purpose of data analysis, matched logistics analysis was used. Results: The study participants consisted of 3843 children and adolescents (response rate 91.5) with mean (SD) age of 12.45 (3.04) years. Totally 49.4 of students were girls and 71.4 lived in urban areas. Three dietary patterns were obtained: Healthy, Western, and Sweet. Prevalence of MetS was 5 (boy 5.5 and girl 4.5). Results of multivariate analysis show that students with Sweet dietary patterns were at higher risk for abdominal obesity (OR 1.29; 95 CI 1.01-1.66), elevated blood pressure (OR 1.35; 95 CI 1.01-1.81) and MetS (OR 1.33; 95 CI 1.02-1.74). The two other dietary patterns were not associated with MetS and its components. Conclusion: Sweet dietary pattern increase the risk of MetS and some its components in Iranian children and adolescents. This finding provides valuable information for effective preventive strategies of MetS based on diet rather than medication to maintain healthy lifestyle habits. © 2018 The Author(s)

Sustainability of Global Golden Inland Waterways

Sustainable inland waterways should meet the needs of navigation without compromising the health of riverine ecosystems. Here we propose a hierarchical model to describe sustainable development of the Golden Inland Waterways (GIWs) which are characterized by great bearing capacity and transport need. Based on datasets from 66 large rivers (basin area > 100,000 km2) worldwide, we identify 34 GIWs, mostly distributed in Asia, Europe, North America, and South America, typically following a three-stage development path from the initial, through to the developing and on to the developed stage. For most GIWs, the exploitation ratio, defined as the ratio of actual to idealized bearing capacity, should be less than 80% due to ecological considerations. Combined with the indices of regional development, GIWs exploitation, and riverine ecosystem, we reveal the global diversity and evolution of GIWs' sustainability from 2015 to 2050, which highlights the importance of river-specific strategies for waterway exploitation worldwide