Tracking Turbulent Coherent Structures by Means of Neural Networks

[EN] The behaviours of individual flow structures have become a relevant matter of study in turbulent flows as the computational power to allow their study feasible has become available. Especially, high instantaneous Reynolds Stress events have been found to dominate the behaviour of the logarithmic layer. In this work, we present a viability study where two machine learning solutions are proposed to reduce the computational cost of tracking such structures in large domains. The first one is a Multi-Layer Perceptron. The second one uses Long Short-Term Memory (LSTM). Both of the methods are developed with the objective of taking the the structures' geometrical features as inputs from which to predict the structures' geometrical features in future time steps. Some of the tested Multi-Layer Perceptron architectures proved to perform better and achieve higher accuracy than the LSTM architectures tested, providing lower errors on the predictions and achieving higher accuracy in relating the structures in the consecutive time steps.This work was supported by RTI2018-102256-B-I00 of MINECO/FEDER. The computations of the new simulations were made possible by a generous grant of computing time from the Barcelona Supercomputing Centre, reference AECT-2020-2-0005.Aguilar-Fuertes, JJ.; Noguero-Rodríguez, F.; Jaen Ruiz, JC.; García-Raffi, LM.; Hoyas, S. (2021). Tracking Turbulent Coherent Structures by Means of Neural Networks. Energies. 14(4):1-15. https://doi.org/10.3390/en1404098411514

Geoheritage as an educational resource and educational resources as heritage

El presente trabajo muestra una compilación de experiencias didácticas que emplean el patrimonio geológico como herramienta pedagógica en la enseñanza de las materias relacionadas con las Ciencias de la Tierra. El objetivo de todas ellas es acercar al alumnado al conocimiento y comprensión de los procesos que acontecen en nuestro planeta, con la finalidad de lograr un acercamiento y sensibilización hacia los mismos. Las seis propuestas seleccionadas presentan variedad en cuanto al contexto territorial de desarrollo de las actividades, a los contenidos y niveles trabajados (desde Enseñanza Secundaria hasta estudios universitarios) y a las metodologías utilizadas para la transmisión de dichos contenidos. Dentro de esta diversidad pueden distinguirse dos grupos de actividades diferentes. El primero de ellos se basa en el desarrollo de experiencias pedagógicas en localidades cuyas características geológicas resultan modélicas, únicas y/o espectaculares. Por el contrario, el segundo conjunto de actividades se centra en el trabajo de los recursos geológicos presentes en el entorno próximo del centro educativo. En ellas se explota su valor patrimonial, es decir, su potencial didáctico para abordar el estudio de la historia geológica del territorio. A través de las actividades incluidas en este compendio, se evidencia la validez de ambos tipos de aproximaciones y, al mismo tiempo, se debaten y realzan algunas de las virtudes más destacables de cada una de ellas. De esta manera, este catálogo podría resultar útil e inspirador para posibles planteamientos futuros.This manuscript presents a compilation of didactic experiences, which address the teaching of Earth Sciences through the knowledge of geological heritage. The aim of these proposals is to promote students’ comprehension of the Earth processes so that they may develop a positive attitude towards them. The six activities chosen offer a catalogue with a variety of sites, methodologies, contents and levels. Within this variety, the activities shown can be gathered into two separate groups. On the one hand, the first group collects experiences, which use geological heritage, i.e., the experiences are developed in places whose geological content is exemplary, unique and/or spectacular. On the other hand, the second group is focused on the geologic resources in the neighborhood of the school. These sites have heritage value, that is, an educational value for studying the geologic history of their territory. The activities drawn together show that both viewpoints are useful, and the benefits of each are pointed out. Consequently, this catalogue might be useful and inspiring for forthcoming attempts in this field

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality