CONSTRUCTION OF A NEW FAMILY OF EFFICIENT IMBEDDED POLYNOMIALS WITH DISTINCT COEFFICIENTS

We propose a new family of multi-purpose imbedded polynomials having distinct coefficients. There exist relationships between various coefficients of the members of the family, which considerably reduce the computational cost of development as well as using any number of members of the family in a particular problem. Every member polynomial of degree n going through (n+1) focuses {(xi, yi): i=0,1….......n} can be constructed very easily from another member having degree (n-1). In this paper, it is shown that the family of polynomials M exists and is efficient, reliable and more accurate as compared to other available techniques. The family has been successfully applied to the problem of interpolation in this paper. Therefore, the family M is also called the Malik‘s Imbedded Interpolating Polynomials (M.I.I.P). The family M gives similar results as compared to Lagrange Interpolation as for as accuracy is concerned but they are more efficient. The proposed polynomials are more efficient, more stable and more reliable as compared to other traditional interpolation methods due to remarkable reduction in mathematical operations. Our approach and the design of the method is different of available methods of prototype interpolation Methods. We have considered the drawbacks of other methods and eliminated from our approach. The superiority of the family is established and reported

Historical Analysis of Bank Profitability Using CAMEL Parameters: Role of Ownership and Political Regimes in Pakistan

In first sixty years of its existence financial sector of Pakistan has experienced two prominent episodes. One, there was an experimentation with the ownership structure of financial institutions which started with promotion of ownership by the private sector and then in 1970s they were nationalized. Subsequently the process was reversed in the 1990s transferring most of the banking assets back to the private sector. Two, on the political front, for long 33 years autocrat have interrupted the democratic order many times. The objective of this study is to take stock of the performance of banking industry when it was in private hands vis-à-vis when banks were nationalized, and, as a supplement, to evaluate the impact of dictatorship versus democracy on the performance of banking industry. Using historical dataset this study offers analysis of banking sector performance by using CAMEL parameters. Our main findings are that when banks are in private hands their profitability is positively related to quality of their assets and management, and it has negative relation with capital adequacy and liquidity. However when banks are under government ownership asset quality and liquidity become irrelevant in determining the profitability whereas capital adequacy, management quality continue to impact bank profitability. This implies that government ownership works like implicit guarantee for banks (a) that they would remain solvent in the short run], and (b) that it would absorb losses emanating from deterioration of bad assets. A

Prevalence of Depression in Caregivers of Stroke Patients in Karachi, Pakistan

ABSTRACT Background and Objective: Caregivers of patients with chronic debilitating illnesses are at risk of developing mental health problems. The objective of this study is to determine the frequency of depression in caregivers of stroke patients at a tertiary care teaching hospital in Karachi, Pakistan. Methods: A cross-sectional study was conducted among caregivers of stroke, who were recruited from the Aga Khan University Hospital between January 2018 to October 2018. Data was collected through the Urdu Hamilton rating scale for depression (HAM-D-U) and it was analyzed using descriptive and inferential statistics. Results: A total of 136 caregivers participated in the study. Among them, 44.1 % were male and 55.9% were female. The mean age of caregivers was 45.38 ± 10.33 years. Using the HAM-D-U scale, depression was present in 64 (47.1%) of caregivers. Out of them (n=64), 46 (33.8%) had mild depression whereas 18 (13.2%) had moderate depression. Depression was found to have a significant relationship with the age of the patient (p=0.002), education level of caregiver (p= 0.012), employment status of caregiver (p=0.012), being a sole caregiver (p=0.039), and monthly family income (p=0.016). Conclusion: Caring for patients with neurological disorders is highly challenging and demanding. The need for this role may arise unexpectedly in one’s life leaving little space for adjustment and coping. Caregiver depression can be debilitating especially if moderate to severe in intensity. Depression in stroke caregivers can be missed as patients are the center of management . Hence, strategies should be designed and reinforced to screen caregivers for depression with a pathway for easy and timely referral

Perception of the healthcare professionals towards the current trauma and emergency care system in Kabul, Afghanistan: A mixed method study

Background: Trauma and injury contribute to 11% of the all-cause mortality in Afghanistan. The study aimed to explore the perceptions of the healthcare providers (pre and in-hospital), hospital managers and policy makers of the public and private health sectors to identify the challenges in the provision of an effective trauma care in Kabul, Afghanistan.Methods: A concurrent mixed method design was used, including key-informant interviews (healthcare providers, hospital managers and policy makers) of the trauma care system (N = 18) and simultaneous structured emergency care system assessment questionnaire (N = 35) from July 15 to September 25, 2019. Interviews were analyzed using content analysis approach and structured questionnaire data were descriptively analyzed.Results: Four themes were identified that describe the challenges: 1) pre-hospital care, 2) cohesive trauma management system, 3) physical and human resources and 4) stewardship. Some key challenges were found related to scene and transportation care, in-hospital care and emergency preparedness within the wider trauma care system. Less than 25% of the population is covered by the pre-hospital ambulance system (n = 23, 65.7%) and there is no communication process between health care facilities to facilitate transfer (n = 28, 80%). Less than 25% of patients with an injury requiring emergent surgery have access to surgical care in a staffed operating theatre within 2 h of injury (n = 19, 54.2%) and there is no regular assessment of the ability of the emergency care system to mobilize resources (human and physical) to respond to disasters, and other large-scale emergencies (n = 28, 80%).Conclusion: This study highlighted major challenges in the delivery of trauma care services across Kabul, Afghanistan. Systematic improvement in the workforce training, structural organization of the trauma care system and implementing externally validated clinical guidelines for trauma management could possibly enhance the functions of the existing trauma care services. However, an integrated state-run trauma care system will address the current burden of traumatic injury more effectively within the wider healthcare system of Afghanistan

Transcriptome profiling of staphylococcus aureus associated extracellular vesicles reveals presence of small RNA-cargo

Bacterial extracellular vesicles (EVs) have a vital role in bacterial pathogenesis. However, to date, the small RNA-cargo of EVs released by the opportunistic pathogen Staphylococcus aureus has not been characterized. Here, we shed light on the association of small RNAs with EVs secreted by S. aureus MSSA476 cultured in iron-depleted bacteriologic media supplemented with a subinhibitory dosage of vancomycin to mimic infection condition. Confocal microscopy analysis on intact RNase-treated EVs indicated that RNA is associated with EV particles. Transcriptomic followed by bioinformatics analysis of EV-associated RNA revealed the presence of potential gene regulatory small RNAs and high levels of tRNAs. Among the EV-associated enriched small RNAs were SsrA, RsaC and RNAIII. Our finding invites new insights into the potential role of EV-associated RNA as a modulator of host-pathogen interaction. Introductio

Magnetite Molybdenum Disulphide Nanofluid of Grade Two: A Generalized Model with Caputo-Fabrizio Derivative

Heat and mass transfer analysis in magnetite molybdenum disulphide nanofluid of grade two is studied. MoS2 powder with each particle of nanosize is dissolved in engine oil chosen as base fluid. A generalized form of grade-two model is considered with fractional order derivatives of Caputo and Fabrizio. The fluid over vertically oscillating plate is subjected to isothermal temperate and species concentration. The problem is modeled in terms of partial differential equations with sufficient initial conditions and boundary conditions. Fractional form of Laplace transform is used and exact solutions in closed form are determined for velocity field, temperature and concentration distributions. These solutions are then plotted for embedded parameters and discussed. Results for the physical quantities of interest (skin friction coefficient, Nusselt number and Sherwood number) are computed in tables. Results obtained in this work are compared with some published results from the open literature

Perceived Stress and Emotional Exhaustion among Undergraduate Medical Students of Gujranwala Medical College, Pakistan

Objective: To determine a student's performance. A survey of undergraduate medical students was done to determine the factors linked to increased stress and emotional tiredness among medical students at Gujranwala Medical College (GMC) Pakistan. Material and Methods:  Data was collected using a structured questionnaire collected from undergraduate medical students. Information related to stress, nervousness, being upset, daily life restlessness, being irritated, being focused, satisfaction with the lecturing, financial strains, family-related stress, living problems, and career, was collected from the respondents via proforma with permission. Results:  40.4% of students felt they had often faced stress during their last month with 37.1% facing unexpected events. Often students (34.4%) found restlessness during their last month with 39.1% of subjects feeling irritated by things happening around them. Some 35.8% of subjects had given thoughts to the future, 26.5% felt worthless and 33.1% forgot simple things or tasks. 39.1% felt they had difficulty focusing on the tasks given to them. Financial strain was always there in 3.3% and was rarely felt in 33.8% of subjects.  Family-related problems were always there in 7.3% of subjects. 33.1% always felt dissatisfied with the quality of food in the mess. 29.8% of subjects felt they were unable to fulfill their parents’ expectations while 22.5% felt they face stress about their career. Conclusion:  40% of students are experiencing various forms of stress and emotional exhaustion. 33 percent of students always felt tension due to messed-up food, and 26.5 percent felt they always felt alone to deal with their problems.

Client Satisfaction towards Quality of Health Services: An Assessment at Primary Healthcare of District Gujranwala

This survey designed to evaluate the satisfaction level and the factors that affect the patient satisfaction regarding health care delivery services with the aim to improve the services in the primary health care settings of Gujranwala. A Cross Sectional Study done on randomly selected patients attending the basic health units of Gujranwala, with more than18 years of age. Pretested structured "Liker scale questionnaire" was used for data collection. Out of total respondents, 62 (41.3%) clients were satisfied with the services provided by the basic health units of Gujranwala. The factors identified to determine patient satisfaction were accessibility of services, behavior of staff, health education, level of cleanliness, drug availability and miscellaneous services. Not a single ranked area of satisfaction noticed. Client’s occupation and income had significant relationship with the patient satisfaction level. Gender, age, and education of clients were not contributing factors; they not affect the client satisfaction level.Less than half clients were satisfied with the services provided by the basic health units. Management of health facilities needs to improve the services

Microbial Contamination in Drinking Water of Saggiyan-Lahore, Pakistan

The present study was carried to evaluate the physico-chemical parameters and microbial contamination of drinking water in the area of Saggiyan, Lahore. The tested water samples (S1-S30) were found to contain 199.6-402 mg/L TDS, 196-260 ppm EC, 196-260 ppm Hardness, 0.8-17 NTU turbidity, 169-290 mg/L alkalinity, 0-0.1 ppb arsenic and 0-0.1 ppm fluoride contents. 95% of the water samples were found contaminated with fecal coliforms while 27% of the samples had shown the presence of E. coli. Though the physico-chemical parameters of most water samples were found in the safe limits of WHO, however, the presence of microbial contamination rendered it non-suitable for drinking purposes

Impact of worker demographics and shift rotation on work stress factors in manufacturing

Work Stress is a barrier towards productivity and efficiency in manufacturing sector. Various factors of stress interact with the demographics such as age, education, experience, marital status and smoking habits of workers. Different workers exhibit different reactions towards work stress. To enhance productivity, manufacturing industry is utilizing night shift. However, night shift work is against the natural tendency of humans. The impact of rotating shift in context of work-stress of the workers is an area of concern. To understand the impact of demographics and shift rotation on work-stress of the workers, a quantitative study was undertaken in a medium sized automotive organization. The case organization was explored through a survey questionnaire administered to both day and night shift workers and analysed through Non parametric Spearman correlation and Mann Whitney U Test. The study highlights the need for effective reward and gratification scheme (Young Worker Avg 3.12 – Old Worker Avg 3.82), taking care of old age workers (Muscle Pain Old Avg 4.47 – Young Avg 3.84), reducing the smoking habit (Depression Smoking Avg 3.79 – Non Smoking Avg 3.12) (Fatigue Smoking Avg 3.92 – Non Smoking Avg 3.06), fostering social community and teamwork. Night shift may enhance production but should not be accepted as an ideal solution. The downsides and ill effects of the unnatural night shift work in the form of work stress are identified and should be reduced by management