Performance and carcass characteristics of lambs fed diets with fat and vitamin E

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG)Empresa de Pesquisa Agropecu?ria de Minas Gerais (EPAMIG)Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq)Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)This experiment aimed to determine the influence of diets with inclusion of protected fat and vitamin E on performance, yield and carcass characteristics of feedlot lambs with different weights. Thirty-two non-castrated Santa Ines lambs were fed diets with a ratio of 40% forage and 60% concentrate ad libitum, with presence or absence of protected fat and/or vitamin E, in a total of four diets. Two weights of early containment were also considered: between 20 and 25 kg and between 30 and 35 kg. All animals were slaughtered at 84 days of confinement. Animals fed diets without addition of protected fat, regardless of the use of vitamin E, had the highest intakes of dry matter, crude protein, neutral detergent fiber and ash, and decreased intake of ether extract. The variables investigated did not affect daily weight gain and total gain. Feed conversion was better for the lighter confined animals not fed protected fat. The heavier feedlot lambs fed diets with vitamin E showed higher cold carcass. The warm carcass for the lighter animals confined fed with vitamin E, and the heavier ones, fed with protected fat and vitamin E, showed the best yields of cold carcass. Objective measures of the carcass cold had the highest mean for heavier feedlot lambs. The addition of fat in the diet reduces the intake of dry matter and increases the ether extract. Although the inclusion of vitamin has no effect on intake of nutrients, it protects the carcasses from losses during cooling, and weight differences at containment directly reflect the measures of the carcasses

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023

Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population. Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care. It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations. Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced. Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM). Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance. Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial. La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización. Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones. Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA. La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA). Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia. Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial. A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização. Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações. Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA. A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA). Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz). Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento

VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad

Acta de congresoLa conmemoración de los cien años de la Reforma Universitaria de 1918 se presentó como una ocasión propicia para debatir el rol de la historia, la teoría y la crítica en la formación y en la práctica profesional de diseñadores, arquitectos y urbanistas. En ese marco el VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad constituyó un espacio de intercambio y reflexión cuya realización ha sido posible gracias a la colaboración entre Facultades de Arquitectura, Urbanismo y Diseño de la Universidad Nacional y la Facultad de Arquitectura de la Universidad Católica de Córdoba, contando además con la activa participación de mayoría de las Facultades, Centros e Institutos de Historia de la Arquitectura del país y la región. Orientado en su convocatoria tanto a docentes como a estudiantes de Arquitectura y Diseño Industrial de todos los niveles de la FAUD-UNC promovió el debate de ideas a partir de experiencias concretas en instancias tales como mesas temáticas de carácter interdisciplinario, que adoptaron la modalidad de presentación de ponencias, entre otras actividades. En el ámbito de VIII Encuentro, desarrollado en la sede Ciudad Universitaria de Córdoba, se desplegaron numerosas posiciones sobre la enseñanza, la investigación y la formación en historia, teoría y crítica del diseño, la arquitectura y la ciudad; sumándose el aporte realizado a través de sus respectivas conferencias de Ana Clarisa Agüero, Bibiana Cicutti, Fernando Aliata y Alberto Petrina. El conjunto de ponencias que se publican en este Repositorio de la UNC son el resultado de dos intensas jornadas de exposiciones, cuyos contenidos han posibilitado actualizar viejos dilemas y promover nuevos debates. El evento recibió el apoyo de las autoridades de la FAUD-UNC, en especial de la Secretaría de Investigación y de la Biblioteca de nuestra casa, como así también de la Facultad de Arquitectura de la UCC; va para todos ellos un especial agradecimiento

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

BACKGROUND: A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. METHODS: This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5 × 1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1 - relative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. FINDINGS: Between April 23 and Nov 4, 2020, 23 848 participants were enrolled and 11 636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0-75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4-97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8-80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74 341 person-months of safety follow-up (median 3·4 months, IQR 1·3-4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. INTERPRETATION: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials. FUNDING: UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, Rede D'Or, Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and AstraZeneca

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Background A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. Methods This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5 × 1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1 - relative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. Findings Between April 23 and Nov 4, 2020, 23 848 participants were enrolled and 11 636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0–75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4–97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8–80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74 341 person-months of safety follow-up (median 3·4 months, IQR 1·3–4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. Interpretation ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials

Performance of Santa In?s lambs fed diets with inclusion of protected fat and vitamin E.

Submitted by Rodrigo Martins Cruz ([email protected]) on 2015-10-26T11:43:04Z No. of bitstreams: 2 Adriana_Paiva_Paula_Pinto.pdf: 808282 bytes, checksum: cbd4f16f675570942d78c7eb503d2425 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5)Approved for entry into archive by Rodrigo Martins Cruz ([email protected]) on 2015-10-26T11:43:40Z (GMT) No. of bitstreams: 2 Adriana_Paiva_Paula_Pinto.pdf: 808282 bytes, checksum: cbd4f16f675570942d78c7eb503d2425 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5)Made available in DSpace on 2015-10-26T11:43:40Z (GMT). No. of bitstreams: 2 Adriana_Paiva_Paula_Pinto.pdf: 808282 bytes, checksum: cbd4f16f675570942d78c7eb503d2425 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) Previous issue date: 2010Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)Funda??o de Amparo ? Pesquisa do estado de Minas Gerais (FAPEMIG)O experimento foi conduzido na Universidade Federal de Lavras, objetivando-se determinar a influ?ncia de dietas com inclus?o de gordura protegida e vitamina E sobre o desempenho, rendimentos, caracter?sticas de carca?a e de qualidade de carne de cordeiros confinados com diferentes pesos. Utilizaram-se 32 cordeiros Santa In?s n?o-castrados recebendo dietas com propor??o de 40% de volumoso e 60% de concentrado, ? vontade, com presen?a ou aus?ncia de gordura protegida e/ou vitamina E, totalizando 4 dietas. Foram considerados ainda dois pesos de in?cio de confinamento: entre 20 e 25 kg; e entre 30 e 35 kg.Todos os animais foram abatidos com 84 dias de confinamento. Os animais alimentados com dietas sem adi??o de gordura protegida, independente do uso de vitamina E, apresentaram os maiores consumos de mat?ria seca, prote?na bruta, fibra em detergente neutro e cinza, e os menores consumos de extrato et?reo. Os ganhos de peso total e di?rio n?o foram influenciados pelas vari?veis avaliadas. A convers?o alimentar foi melhor nos animais confinados em pesos mais leves recebendo dietas sem gordura protegida. Os cordeiros confinados mais pesados alimentados com dietas com vitamina E apresentaram maiores pesos de carca?a fria. Os maiores rendimentos de carca?a quente foram para os animais confinados mais leves recebendo dietas com vitamina E, e para os mais pesados alimentados com dietas contendo gordura protegida e vitamina E, esses tamb?m apresentaram os maiores rendimentos de carca?a fria. As medidas objetivas realizadas na carca?a fria apresentaram as maiores m?dias para os cordeiros confinados mais pesados. Os cordeiros confinados de 20-25 kg apresentaram as maiores percentagens de trato gastrintestinal. Os cordeiros mais pesados recebendo dietas com gordura protegida tiveram as maiores percentagens de dep?sitos de gordura. As maiores m?dias para o rendimento do lombo foram dos cordeiros de 30-35 kg que consumiram dietas sem gordura. Os par?metros f?sicos de qualidade da carne no Longissimus dorsi n?o foram influenciados por nenhuma das vari?veis avaliadas, entretanto para o fil? mignon houve diferen?a. A adi??o de gordura protegida na dieta reduz o consumo de mat?ria seca, aumenta o consumo de extrato et?reo, e n?o apresenta resultados relevantes quanto ?s caracter?sticas da carca?a e qualidade de carne. Apesar da inclus?o de vitamina n?o ter efeito expressivos sobre os fatores avaliados, ela protege as carca?as das perdas durante o resfriamento. O confinamento de cordeiros com diferentes pesos n?o apresenta vantagens quanto ?s caracter?sticas estudadas, exceto para as medidas de carca?a fria e percentagens do trato gastrintestinal.Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Zootecnia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2010.ABSTRACT The experiment was conducted at the Universidade Federal de Lavras, aiming to determine the influence of diets with inclusion of protected fat and vitamin E on performance, yield and carcass characteristics of feedlot lambs with different weights. We used 32 uncastrated Santa Ines lambs fed on diets with a ratio of 40% forage and 60% concentrate ad libitum, with presence or absence of protected fat and / or vitamin E, a total of four diets. Were still considered two weights of early containment: between 20 and 25 kg and between 30 and 35 kg. All animals were slaughtered at 84 days of confinement. Animals fed on diets without added fat protected, regardless of the use of vitamin E, had the highest intakes of dry matter, crude protein, neutral detergent fiber and ash, and decreased intake of ether extract. The total weight gains and daily were not influenced by variables. Feed conversion was better for the animals confined in lighter weights fed without protected fat. The heavier feedlot lambs fed on diets with vitamin E showed higher cold carcass. The higher incomes of warm carcass were for the lighter confined animals fed with vitamin E, and for the heavier ones fed with protected fat and vitamin E, they also had the highest yields of cold carcass. Objective measures of the cold carcass had the highest average for the heavier feedlot lambs. The feedlot lambs of 20-25 kg showed the highest percentages of the gastrointestinal tract. The heaviest lambs fed on protected fat had the highest percentages of fat deposits. The largest average yield of loin were lambs of 30-35 kg fed on diets without fat. The physical parameters of meat quality in Longissimus dorsi were not affected by any variable evaluated, however for the filet mignon there was a difference. The addition of fat in the diet reduces the dry matter intake, increases consumption of fat, and does not present significant results concerning the characteristics of carcass and meat quality. Despite the inclusion of vitamin have no significant effect on the evaluated factors, it protects the carcasses of the losses during cooling. Confinement of lambs with different weights have no advantages for the studied traits, except for measures of cold carcass

Performance of Santa In?s lambs fed diets with inclusion of protected fat and vitamin E.

O experimento foi conduzido na Universidade Federal de Lavras, objetivando-se determinar a influ?ncia de dietas com inclus?o de gordura protegida e vitamina E sobre o desempenho, rendimentos, caracter?sticas de carca?a e de qualidade de carne de cordeiros confinados com diferentes pesos. Utilizaram-se 32 cordeiros Santa In?s n?o-castrados recebendo dietas com propor??o de 40% de volumoso e 60% de concentrado, ? vontade, com presen?a ou aus?ncia de gordura protegida e/ou vitamina E, totalizando 4 dietas. Foram considerados ainda dois pesos de in?cio de confinamento: entre 20 e 25 kg; e entre 30 e 35 kg.Todos os animais foram abatidos com 84 dias de confinamento. Os animais alimentados com dietas sem adi??o de gordura protegida, independente do uso de vitamina E, apresentaram os maiores consumos de mat?ria seca, prote?na bruta, fibra em detergente neutro e cinza, e os menores consumos de extrato et?reo. Os ganhos de peso total e di?rio n?o foram influenciados pelas vari?veis avaliadas. A convers?o alimentar foi melhor nos animais confinados em pesos mais leves recebendo dietas sem gordura protegida. Os cordeiros confinados mais pesados alimentados com dietas com vitamina E apresentaram maiores pesos de carca?a fria. Os maiores rendimentos de carca?a quente foram para os animais confinados mais leves recebendo dietas com vitamina E, e para os mais pesados alimentados com dietas contendo gordura protegida e vitamina E, esses tamb?m apresentaram os maiores rendimentos de carca?a fria. As medidas objetivas realizadas na carca?a fria apresentaram as maiores m?dias para os cordeiros confinados mais pesados. Os cordeiros confinados de 20-25 kg apresentaram as maiores percentagens de trato gastrintestinal. Os cordeiros mais pesados recebendo dietas com gordura protegida tiveram as maiores percentagens de dep?sitos de gordura. As maiores m?dias para o rendimento do lombo foram dos cordeiros de 30-35 kg que consumiram dietas sem gordura. Os par?metros f?sicos de qualidade da carne no Longissimus dorsi n?o foram influenciados por nenhuma das vari?veis avaliadas, entretanto para o fil? mignon houve diferen?a. A adi??o de gordura protegida na dieta reduz o consumo de mat?ria seca, aumenta o consumo de extrato et?reo, e n?o apresenta resultados relevantes quanto ?s caracter?sticas da carca?a e qualidade de carne. Apesar da inclus?o de vitamina n?o ter efeito expressivos sobre os fatores avaliados, ela protege as carca?as das perdas durante o resfriamento. O confinamento de cordeiros com diferentes pesos n?o apresenta vantagens quanto ?s caracter?sticas estudadas, exceto para as medidas de carca?a fria e percentagens do trato gastrintestinal.Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)Funda??o de Amparo ? Pesquisa do estado de Minas Gerais (FAPEMIG)Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Zootecnia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2010.ABSTRACT The experiment was conducted at the Universidade Federal de Lavras, aiming to determine the influence of diets with inclusion of protected fat and vitamin E on performance, yield and carcass characteristics of feedlot lambs with different weights. We used 32 uncastrated Santa Ines lambs fed on diets with a ratio of 40% forage and 60% concentrate ad libitum, with presence or absence of protected fat and / or vitamin E, a total of four diets. Were still considered two weights of early containment: between 20 and 25 kg and between 30 and 35 kg. All animals were slaughtered at 84 days of confinement. Animals fed on diets without added fat protected, regardless of the use of vitamin E, had the highest intakes of dry matter, crude protein, neutral detergent fiber and ash, and decreased intake of ether extract. The total weight gains and daily were not influenced by variables. Feed conversion was better for the animals confined in lighter weights fed without protected fat. The heavier feedlot lambs fed on diets with vitamin E showed higher cold carcass. The higher incomes of warm carcass were for the lighter confined animals fed with vitamin E, and for the heavier ones fed with protected fat and vitamin E, they also had the highest yields of cold carcass. Objective measures of the cold carcass had the highest average for the heavier feedlot lambs. The feedlot lambs of 20-25 kg showed the highest percentages of the gastrointestinal tract. The heaviest lambs fed on protected fat had the highest percentages of fat deposits. The largest average yield of loin were lambs of 30-35 kg fed on diets without fat. The physical parameters of meat quality in Longissimus dorsi were not affected by any variable evaluated, however for the filet mignon there was a difference. The addition of fat in the diet reduces the dry matter intake, increases consumption of fat, and does not present significant results concerning the characteristics of carcass and meat quality. Despite the inclusion of vitamin have no significant effect on the evaluated factors, it protects the carcasses of the losses during cooling. Confinement of lambs with different weights have no advantages for the studied traits, except for measures of cold carcass