139 research outputs found

    Numerical Computation of Electric Field and Charge Structure of a Typical Tropical Thunderstorm

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    Cloud charge dynamics are usually determined from ground measurements. Where in-situ cloud measurements are available they sometimes modify the cloud structure; and this can be expensive, and merely diagnostic at best. In this work, Poisson integral formula is simplified by adapting the Bessel functions to obtain the cascaded potential gradients at any point on ground as a result of charge distribution in cylindrical volumes. The model represents the cloud charges as a vertical sequence of axially aligned, uniformly-charged densities of cylindrical disk(slices), The resulting expressions for the potential gradient is solved numerically as a functions of  normalized vertical and horizontal distances to model the vertical electric field and potential profiles below a typical thunderstorm. Keywords: Electric field, Bessel functions, Charge structure, Cylindrical charge model, Lower positive charge center

    Numerical Simulation of Electric Field and Charge Structure within an Isolated Thunderstorm

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    The study of electrical structure of thunderstorm is a deterministic factor in characterizing the behavior of lightning. It is impossible to measure the value of electric field at every point within the thunderstorm, even when the in situ measurements are made, they are done along the path of balloon-borne instruments or other methods employed in the measurement. The average data obtained from past measurements were employed in determining the electric field generated by the thunderstorm as observed along the horizontal distance using the cylindrical charge model. The data consisted of a screening charge layer firstly located “between” 1.8-2.0 km and later between 10.0-10.2 km respectively above the ground level (agl) to see the effect of positioning on the resultant computation. The lower positive charge center with radius ranging from 0.5 km to 2.0 km was placed at various heights between 2.0 and 6.0 km. This is to determine the effect of cloud base height on the resulting field profile. The main negative charge is accommodated between 4.0 and 7.5 km and the upper positive charge layer existed between 7.5- 10.0 km agl for a cloud base height of 2.0 km and 6.0- 9.5 km agl for a negative charge layer, 7.5- 11.0 km agl for upper positive charge with a cloud base of 4.0 km high. The resulting potential gradient (PG) profiles were obtained for spatial distribution with screening charge layer playing no active role in the thunderstorm electrification. The effects of wind shear due to increasing wind speed with height were also investigated to have a clear picture of the cloud charge dynamics; hence the vertical PG patterns produced by a moving thunderstorm for various cloud cell life-times were modeled. The results showed that a typical tropical thunderstorm can exhibit charge layer more than the normal tripolar structure, and the pocket of lower positive charge can be more than one or larger than the usual size. Wind shear was found to enhance lightning discharges at the surface of charge discontinuities. Keywords: Potential gradient, Wind shear, Cloud charge, Lower positive charge center, Noninductive charging.

    One Step Continuous Hybrid Block Method for the Solution of y'''=f(x,y,y',y'')

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    In this paper, we present a block method for the direct solution of third order initial value problems of ordinary differential equations. Collocation and interpolation approach was adopted to generate a continuous linear multistep method which was then solved for the independent solution to give a continuous block method. We evaluated the result at selected grid points to give a discrete block which eventually gave simultaneous solutions at both grid and off grid points.  The one-step block method is consistent and A -stable, with good region of absolute stability. Experimental results confirmed the superiority of the new scheme over an existing method. Keywords: consistent, convergent, collocation, hybrid points, independent solution, interpolation, zero stabl

    Second law analysis for hydromagnetic couple stress fluid flow through a porous channel

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    In this work, the combined effects of magnetic field and ohmic heating on the entropy generation rate in the flow of couple stress fluid through a porous channel are investigated. The equations governing the fluid flow are formulated, non-dimensionalised and solved using a rapidly convergent semi-analytical Adomian decomposition method (ADM). The result of the computation shows a significant dependence of fluid’s thermophysical parameters on Joule’s dissipation as well as decline in the rate of change of fluid momentum due to the interplay between Lorentz and viscous forces. Moreover, the rate of entropy generation in the flow system drops as the magnitude of the magnetic field increases

    TWO STEPS BLOCK METHOD FOR THE SOLUTION OF GENERAL SECOND ORDER INITIAL VALUE PROBLEMS OF ORDINARY DIFFERENTIAL EQUATION

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    In this paper, an implicit block linear multistep method for the solution of ordinary differential equation        was extended to the general form of differential equation. This method is self starting and does not        need   a   predictor   to   solve   for   the   unknown   in   the   corrector.   The   method   can   also   be   extended   to        boundary   value   problems  without   additional   cost.   The  method was   found to   be  efficient   after   being        tested with numerical problems of second order

    Numerical study of nonlinear heat transfer from a wavy surface to a high permeability medium with pseudo-spectral and smoothed particle methods

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    Motivated by petro-chemical geological systems, we consider the natural convection boundary layer flow from a vertical isothermal wavy surface adjacent to a saturated non-Darcian high permeability porous medium. High permeability is considered to represent geologically sparsely packed porous media. Both Darcian drag and Forchheimer inertial drag terms are included in the velocity boundary layer equation. A high permeability medium is considered. We employ a sinusoidal relation for the wavy surface. Using a set of transformations, the momentum and heat conservation equations are converted from an (x, y) coordinate system to an (x,η) dimensionless system. The two-point boundary value problem is then solved numerically with a pseudo-spectral method based on combining the Bellman–Kalaba quasi linearization method with the Chebyschev spectral collocation technique (SQLM). The SQLM computations are demonstrated to achieve excellent correlation with smoothed particle hydrodynamic (SPH) Lagrangian solutions. We study the effect of Darcy number (Da), Forchheimer number (Fs), amplitude wavelength (A) and Prandtl number (Pr) on the velocity and temperature distributions in the regime. Local Nusselt number is also computed for selected cases. The study finds important applications in petroleum engineering and also energy systems exploiting porous media and undulating (wavy) surface geometry. The SQLM algorithm is shown to be exceptionally robust and achieves fast convergence and excellent accuracy in nonlinear heat transfer simulations

    ISOLATION AND CHARACTERIZATION OF CHEMICAL CONSTITUENTS FROM Chrysophyllum albidum G. DON-HOLL. STEM-BARK EXTRACTS AND THEIR ANTIOXIDANT AND ANTIBACTERIAL PROPERTIES

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    Background: The plant, Chrysophyllum albidum is indigenous to Nigeria and its stem-bark has found relevance in folkloric medicine for infections and oxidative stress linked diseases medicaments. The study targets to isolate the chemical constituents accountable for the antioxidant and antibacterial actions of the plant stem-bark to substantiate some of its ethnomedicinal uses. Materials and Methods: Stem-bark extract of Chrysophyllum albidum was obtained from 80 % ethanol was partitioned in sequence with ethyl acetate (EtOAc) and n-butanol. The solvent fractions and isolated compounds were verified for antioxidant chattels utilizing 2-2-diphenyl-1-picrylhydrazyl. Antibacterial actions were also assessed by agency of agar-diffusion and broth micro dilution methods. EtOAc fraction was on many occasions chromatographed on silica and Sephadex LH-20 column to afford four compounds and their chemical structures were proven with the employment of NMR (1D and 2D) and MS. Results: Chromatographic fractionation of EtOAc fraction with the premier antioxidant and antimicrobial activities afforded stigmasterol (1), epicatechin (2), epigallocatechin (3) and procyanidin B5 (4). Procyanidin B5 isolated for the first time from Chrysophyllum genus proven the supreme antioxidant activity with IC50 values of 8.8 µM and 11.20 µM in DPPH and nitric oxide assays respectively and equally established the ultmost inhibitory activity against Escherichia coli (MIC 156.25 μg/mL), Staphylococcus aureus (MIC 156.25 μg/mL), Pseudomonas aeruginosa (MIC 625 μg/mL) and Bacillus subtilis (MIC 156.25 μg/mL). Conclusion: The antibacterial and antioxidant activities of epicatechin, epigallocatechin and procyanidin B5 isolated from Chrysophyllum albidum stem-bark substantiate the folkloric use

    Oscillatory dissipative conjugate heat and mass transfer in chemically-reacting micropolar flow with wall couple stress : a finite element numerical study

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    High temperature non-Newtonian materials processing provides a stimulating area for process engineering simulation. Motivated by emerging applications in this area, the present article investigates the time-dependent free convective flow of a chemically-reacting micropolar fluid from a vertical plate oscillating in its own plane adjacent to a porous medium. Thermal radiative, viscous dissipation and wall couple stress effects are included. The Rosseland diffusion approximation is used to model uni-directional radiative heat flux in the energy equation. Darcy’s model is adopted to mimic porous medium drag force effects. The governing two-dimensional conservation equations are normalized with appropriate variables and transformed into a dimensionless, coupled, nonlinear system of partial differential equations under the assumption of low Reynolds number. The governing boundary value problem is then solved under physically viable boundary conditions numerically with a finite element method based on the weighted residual approach. Graphical illustrations for velocity, micro-rotation (angular velocity), temperature and concentration are obtained as functions of the emerging physical parameters i.e. thermal radiation, viscous dissipation, first order chemical reaction parameter etc. Furthermore, friction factor (skin friction), surface heat transfer and mass transfer rates have been tabulated quantitatively for selected thermo-physical parameters. A comparison with previously published paper is made to check the validity and accuracy of the present finite element solutions under some limiting cases and excellent agreement is attained. Additionally, a mesh independence study is conducted. The model is relevant to reactive polymeric materials processing simulation

    Improved thyroid hypoechogenicity following bariatric-induced weight loss in euthyroid adults with severe Obesity-a pilot study

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    Background: Obesity may affect both biochemical thyroid function tests; and thyroid morphology, as assessed using ultrasound scans (US). The aim of the present pilot study was to explore whether weight loss achieved by bariatric surgery alters thyroid US morphology including gray-scale measurements; and/or function in euthyroid adults with severe obesity. Methods: Euthyroid adults (> 18 years) with body mass index (BMI) ≥40 kg/m2 and negative thyroid peroxidase antibodies were assessed at baseline (pre-surgery) and after achieving at least 5% weight loss of their baseline body weight following bariatric surgery. Anthropometric assessments, biochemical/hormonal measurements (TSH, free-T4, free-T3, reverse-T3, and leptin) and thyroid US with gray-scale histogram analysis were performed at the baseline and post-surgery follow-up. Results: Ten Caucasian, euthyroid patients (women/men: 8/2; age: 48.6 ± 3.1 years; BMI: 51.4 ± 1.8 kg/m2) successfully completed this study with significantly decreased body weight (> 5% weight loss), waist circumference and serum leptin levels post-surgery (mean post-surgery follow-up duration: 16.5 ± 2.5 months). In parallel to the observed bariatric-induced weight loss, thyroid US echogenicity increased by 25% (p = 0.03), without significant changes in thyroid volume. No significant changes in thyroid function tests were detected. No significant correlations were observed between the increase in thyroid echogenicity and the decreases in anthropometric parameters and circulating leptin. Conclusion: Our results indicate that in euthyroid adults with severe obesity, marked weight loss achieved by bariatric surgery is associated with a parallel significant increase in the thyroid US echogenicity, suggesting that morphological changes of the thyroid in obesity are reversible with weight loss

    IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter

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    Radiotherapy for head and neck tumors often results in persistent loss of function in salivary glands. Patients suffering from impaired salivary function frequently terminate treatment prematurely because of reduced quality of life caused by malnutrition and other debilitating side-effects. It has been previously shown in mice expressing a constitutively active form of Akt (myr-Akt1), or in mice pretreated with IGF1, apoptosis is suppressed, which correlates with maintained salivary gland function measured by stimulated salivary flow. Induction of cell cycle arrest may be important for this protection by allowing cells time for DNA repair. We have observed increased accumulation of cells in G2/M at acute time-points after irradiation in parotid glands of mice receiving pretreatment with IGF1. As p21, a transcriptional target of the p53 family, is necessary for maintaining G2/M arrest, we analyzed the roles of p53 and p63 in modulating IGF1-stimulated p21 expression. Pretreatment with IGF1 reduces binding of ΔNp63 to the p21 promoter after irradiation, which coincides with increased p53 binding and sustained p21 transcription. Our data indicate a role for ΔNp63 in modulating p53-dependent gene expression and influencing whether a cell death or cell cycle arrest program is initiated
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