462 research outputs found

    Consortia in Postsecondary Education

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    This article presents the concept of consortia as formal collaborative arrange- ments between institutions, which are designed to enhance academic programs or other services provided. Forty years of experience in the United States are reviewed through the literature, and a synopsis of consortia in Canada is presented. From this review, some "pros and cons" of consortia are raised. Advantages include: reducing duplication, improving quality, increasing program diversity, increasing accessibility, financial advancement, improving communication and more effective planning and control. Cautions raised include: lack of trust, unequal commitment by members, undue emphasis on reducing costs, lack of clear expectations, mismatching membership and mission and irrelevant structure and theory. The authors conclude that the promise of consortia is such that more detailed study of Canadian consortia is warranted

    Ecological Factors Influencing Gastrointestinal Helminths of the Maryland Muskrat Ondatra Zibethicus Linnaeus

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    Role of Heredity in Influencing Mental Disorders and Deficiencies

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    A survey of mental disorders and deficiencies that .are influenced by genetic factors have been undertaken in this report . The materials used in this survey are : (1) textbooks on eugenics and heredity; and (2) periodicals and journals containing recent studies on the mentally defective . It was necessary to include books of psychiatry as well as genetic studies , as the problem is of psychological importance as well as biological. It is the thought that this study will provide a basis of study for the biologist , the psychiatrist , the student , and the interested reader. It was emphatically illustrated in the literature that the problem of mental illness lies in the germ plasm of the general population, rather than the mental defectives themselves who make only a negligible contribution to the increase of the mentally deficient . Mental illness , a condition for which people have been tortured in previous years , should be looked upon as a bodily disorder . The ugly stigma that the illness has carried for many years is being gradually erased. Mental illness affects the whole population; by presenting a problem to the families and friends of the afflicted, it also places a financial burden on the nation. New treatments and approaches are being utilized. The "snake pit" era is gone forever. Geneticists and psychiatrists are cognizant of the fact that the problem does not originate from a single source , and are uniting their efforts to combat this problem of long standing.Natural Scienc

    Australian Orthoptera

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    p. 443-457 : ill. ; 24 cm.Includes bibliographical references

    General Variability Leads to Specific Adaptation Toward Energy Optimal Policies

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    Our nervous systems can learn optimal control policies in response to changes to our bodies, tasks, and movement contexts. For example, humans can learn to adapt their control policy in walking contexts where the energy-optimal policy is shifted along variables such as step frequency or step width. However, it is unclear how the nervous system determines which ways to adapt its control policy. Here, we asked how human participants explore through variations in their control policy to identify more optimal policies in new contexts. We created new contexts using exoskeletons that apply assistive torques to each ankle at each walking step. We analyzed four variables that spanned the levels of the whole movement, the joint, and the muscle: step frequency, ankle angle range, total soleus activity, and total medial gastrocnemius activity. We found that, across all of these analyzed variables, variability increased upon initial exposure to new contexts and then decreased with experience. This led to adaptive changes in the magnitude of specific variables, and these changes were correlated with reduced energetic cost. The timescales by which adaptive changes progressed and variability decreased were faster for some variables than others, suggesting a reduced search space within which the nervous system continues to optimize its policy. These collective findings support the principle that exploration through general variability leads to specific adaptation toward optimal movement policies

    West Indian earwigs

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    p. 635-651, [2] leaves of plates : ill. ; 24 cm.Includes bibliographical references

    Development of a cytology-based multivariate analytical risk index for oral cancer

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    Objectives The diagnosis and management of oral cavity cancers are often complicated by the uncertainty of which patients will undergo malignant transformation, obligating close surveillance over time. However, serial biopsies are undesirable, highly invasive, and subject to inherent issues with poor inter-pathologist agreement and unpredictability as a surrogate for malignant transformation and clinical outcomes. The goal of this study was to develop and evaluate a Multivariate Analytical Risk Index for Oral Cancer (MARIO) with potential to provide non-invasive, sensitive, and quantitative risk assessments for monitoring lesion progression. Materials and methods A series of predictive models were developed and validated using previously recorded single-cell data from oral cytology samples resulting in a “continuous risk score”. Model development consisted of: (1) training base classification models for each diagnostic class pair, (2) pairwise coupling to obtain diagnostic class probabilities, and (3) a weighted aggregation resulting in a continuous MARIO. Results and conclusions Diagnostic accuracy based on optimized cut-points for the test dataset ranged from 76.0% for Benign, to 82.4% for Dysplastic, 89.6% for Malignant, and 97.6% for Normal controls for an overall MARIO accuracy of 72.8%. Furthermore, a strong positive relationship with diagnostic severity was demonstrated (Pearson’s coefficient = 0.805 for test dataset) as well as the ability of the MARIO to respond to subtle changes in cell composition. The development of a continuous MARIO for PMOL is presented, resulting in a sensitive, accurate, and non-invasive method with potential for enabling monitoring disease progression, recurrence, and the need for therapeutic intervention of these lesions

    Orthoptera from Sumatra

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    p. 177-211 : ill. ; 24 cm.Includes bibliographical references

    Ammonium Pertechnetate in Mixtures of Trifluoromethanesulfonic Acid and Trifluoromethanesulfonic Anhydride

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    Ammonium pertechnetate reacts in mixtures of trifluoromethanesulfonic anhydride and trifluoromethanesulfonic acid under final formation of ammonium pentakis(trifluoromethanesulfonato)oxidotechnetate(V), (NH4)2[TcO(OTf)5]. The reaction proceeds only at exact concentrations and under the exclusion of air and moisture via pertechnetyl trifluoromethanesulfonate, [TcO3(OTf)], and intermediate TcVI species. 99Tc nuclear magnetic resonance (NMR) has been used to study the TcVII compound and electron paramagnetic resonance (EPR), 99Tc NMR and X-ray absorption near-edge structure (XANES) experiments indicate the presence of the reduced technetium species. In moist air, (NH4)2[TcO(OTf)5] slowly hydrolyses under formation of the tetrameric oxidotechnetate(V) (NH4)4[{TcO(TcO4)4}4] ⋅10 H2O. Single-crystal X-ray crystallography was used to determine the solid-state structures. Additionally, UV/Vis absorption and IR spectra as well as quantum chemical calculations confirm the identity of the species
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