13 research outputs found
One-step versus two-step screening for diagnosis of gestational diabetes mellitus in Iranian population : A randomized community trial
publishedVersio
Prevalence of and reasons for womenâs, family membersâ, and health professionalsâ preferences for cesarean section in Iran: a mixed-methods systematic review
Abstract: Background: Cesarean section (CS) rates have been increasing globally. Iran has one of the highest CS rates in the world (47.9%). This review was conducted to assess the prevalence of and reasons for womenâs, family membersâ, and health professionalsâ preferences for CS in Iran. Methods and findings: In this mixed-methods systematic review, we searched MEDLINE/PubMed, Embase, CINAHL, POPLINE, PsycINFO, Global Health Library, Google scholar; as well as Iranian scientific databases including SID, and Magiran from 1 January 1990 to 8th October 2019. Primary quantitative, qualitative, and mixed-methods studies that had been conducted in Iran with Persian or English languages were included. Meta-analysis of quantitative studies was conducted by extracting data from 65 cross-sectional, longitudinal, and baseline measurements of interventional studies. For meta-synthesis, we used 26 qualitative studies with designs such as ethnography, phenomenology, case studies, and grounded theory. The Review Manager Version 5.3 and the Comprehensive Meta-Analysis (CMA) software were used for meta-analysis and meta-regression analysis. Results showed that 5.46% of nulliparous women (95% CI 5.38â5.50%; Ď2 = 1117.39; df = 28 [p < 0.00001]; I2 = 97%) preferred a CS mode of delivery. Results of subgroup analysis based on the time of pregnancy showed that proportions of preference for CS reported by women were 5.94% (95% CI 5.86â5.99%) in early and middle pregnancy, and 3.81% (95% CI 3.74â3.83%), in late pregnancy. The heterogeneity was high in this review. Most women were pregnant, regardless of their parity; the risk level of participants were unknown, and some Persian publications were appraised as low in quality. A combined inductive and deductive approach was used to synthesis the qualitative data, and CERQual was used to assess confidence in the findings. Meta-synthesis generated 10 emerging themes and three final themes: âWomenâs factorsâ, âHealth professional factorsâ, andex âHealth organization, facility, or system factorsâ. Conclusion: Despite low preference for CS among women, CS rates are still so high. This implies the role of factors beyond the individual will. We identified a multiple individual, health facility, and health system factors which affected the preference for CS in Iran. Numerous attempts were made in recent years to design, test and implement interventions to decrease unnecessary CS in Iran, such as mother-friendly hospitals, standard protocols for labor and birth, preparation classes for women, midwives, and gynaecologists, and workshops for specialists and midwives through the âhealth sector evolution policyâ. Although these programs were effective, high rates of CS persist and more efforts are needed to optimize the use of CS
Does fasting plasma glucose values 5.1-5.6 mmol/l in the first trimester of gestation a matter?
ObjectivesThe aim of the study was to investigate the effect of treatment on pregnancy outcomes among women who had fasting plasma glucose (FPG) 5.1-5.6 mmol/l in the first trimester of pregnancy.MethodsWe performed a secondary-analysis of a randomized community non-inferiority trial of gestational diabetes mellitus (GDM) screening. All pregnant women with FPG values range 5.1-5.6 mmol/l in the first trimester of gestation were included in the present study (n=3297) and classified to either the (i) intervention group who received treatment for GDM along with usual prenatal care (n=1,198), (ii) control group who received usual-prenatal-care (n=2,099). Macrosomia/large for gestational age (LGA) and primary cesarean-section (C-S) were considered as primary-outcomes. A modified-Poisson-regression for binary outcome data with a log link function and robust error variance was used to RR (95%CI) for the associations between GDM status and incidence of pregnancy outcomes.ResultsThe mean maternal age and BMI of pregnant women in both study groups were similar. There were no statistically significant differences in the adjusted risks of adverse pregnancy outcomes, including macrosomia, primary C-S, preterm birth, hyperbilirubinemia, preeclampsia, NICU-admission, birth trauma, and LBW both groups.ConclusionsIt is found that treating women with first-trimester FPG values of 5.1-5.6 mmol/l could not improve adverse pregnancy outcomes including macrosomia, Primary C-S, Preterm birth, hypoglycemia, hypocalcemia, preeclampsia, NICU admission, Birth trauma and LBW. Therefore, extrapolating the FPG cut-off point of the second trimester to the first âwhich has been proposed by the IADPSG, might therefore not be appropriate.Clinical Trial Registrationhttps://www.irct.ir/trial/518, identifier IRCT138707081281N1
Priority Setting for Improvement of Cervical Cancer Prevention in Iran
Background: Cervical cancer is the fourth most common cancer among women worldwide. Organized cervical
screening and vaccination against human papilloma virus (HPV) have been successful interventions for prevention
of invasive cervical cancer (ICC). Because of cultural and religious considerations, ICC has low incidence in Iran
and many other Muslim countries. There is no organized cervical screening in these countries. Therefore, ICC
is usually diagnosed in advanced stages with poor prognosis in these countries. We performed a priority setting
exercise and suggested priorities for prevention of ICC in this setting.
Methods: We invited experts and researchers to a workshop and asked them to list important suggestions for ICC
prevention in Iran. After merging similar items and removing the duplicates, we asked the experts to rank the
list of suggested items. We used a strategy grid and Go-zone analysis to determine final list of priorities for ICC
prevention in Iran.
Results: From 26 final items suggested as priorities for prevention of ICC, the most important priorities were
developing national guidelines for cervical screening and quality control protocol for patient follow-up and
management of precancerous lesions. In addition, we emphasized considering insurance coverage for cervical
screening, public awareness, and research priorities, and establishment of a cervical screening registry.
Conclusion: A comprehensive approach and implementation of organized cervical screening program is necessary
for prevention of ICC in Iran and other low incidence Muslim countries. Because of high cost for vaccination and
low incidence of cervical cancer, we do not recommend HPV vaccination for the time being in Iran
Reproductive morbidity among Iranian women; issues often inappropriately addressed in health seeking behaviors
<p>Abstract</p> <p>Background</p> <p>Reproductive morbidity has a huge impact on the health and quality of life of women. We aimed to determine the prevalence of reproductive morbidities and the health seeking behavior of a nationally representative sample of Iranian urban women.</p> <p>Methods</p> <p>A sample of 1252 women, aged 18-45 years, was selected using the multi stage, stratified probability sampling procedure. Data were collected through interviews and physical, gynecological and ultrasonographic examinations.</p> <p>Results</p> <p>Reproductive tract infection (RTIs), pelvic organ prolapse (POP) and menstrual dysfunction were the three main groups of morbidities with a prevalence of 37.6%, 41.4% and 30.1%., respectively. Our study demonstrated that 35.1, 34.5 and 9.6 percent of women experienced one, two or these reproductive organ disorders mentioned, respectively, while 20.6 percent of participants had none of these disorders. Findings also showed that the majority of women who suffered from reproductive morbidities (on average two out of three) had not sought appropriate care for these except for infertility.</p> <p>Conclusions</p> <p>Reproductive health morbidities impose a large burden among Iranian women and have negative impact on their reproductive health and wellbeing.</p
Barriers to Pap Smear Test for the Second Time in Women Referring to Health Care Centers in the South of Tehran: A Qualitative Approach
Background: Cervical cancer is a preventable disease with a regular screening program. Many studies have reported a large number of barriers that women had for the first time, but this study decided to find other barriers for the second time pap smear.
Methods: In this qualitative research, data were gathered through in-depth interviews and expressed through conventional content analysis in the form of constant comparison. The participants were 15 women with family profile at 30 health care centers who lived in the south of Tehran and had done Pap smear for one time but didnât do it for the second time.
Results: Three main themes emerged from the analysis of the interviews: negative experiences of the first Pap test were as follows: results of the first time test, readiness for performing the test, getting the test itself, and the site of the first Pap test. Personal barriers to getting the second Pap test were: inattention to time, physical barriers to the second Pap test, and inhibitory beliefs. Perceived social barriers to getting the second Pap test with two sub-themes included social supports and abstract norms.
Conclusion: This study provided other barriers about Pap smear including lack of the spouseâs support, the role of health care providers and physicians in screening program for early diagnosis in women
Womenâs perspectives on health facility and system levels factors influencing mode of delivery in Tehran: a qualitative study
Abstract Background Iran has one of the highest national caesarean section rates worldwide. Few studies explored in-depth the health-facility and health-system level factors that affect womenâs choices on mode of delivery in Iran. The aim of this study was to explore the health-facility and health-system level factors affecting womenâs preferences on mode of delivery in Tehran. Methods We conducted a qualitative study using in-depth face-to-face interviews with women between October 2017 and May 2018. Study participants were sampled purposively from a range of health service settings to include women of varying experiences regarding childbirth. Eligibility criteria were Persian-speaking, women with or without childbirth experiences. All interviews were audio-recorded and lasted 30â45âmin. After verbatim transcription of the interviews, we created a preliminary thematic framework to analyze the data. A combined inductive (themes emerging from the data) and deductive (key concepts across existing frameworks) approach was used during data analysis. Results In total, 26 in-depth interviews were conducted. Five central themes influencing womenâs preferences on mode of delivery emerged from the analysis: (1) health system conditions (important differences between the quality of care provided at private and public hospitals; staff shortages, skills, competency, motivation and also accessibility to staff during the longer time required for a vaginal delivery; policies and protocols on vaginal birth after cesarean, pain relief for vaginal birth, and having companion during labor; (2) standards of care in facilities (physical condition in facilities; physical examinations and procedures; continuous and organized care; ethics); (3) interaction between women and providers (communicating in a supportive manner with women and communication womenâs partners/families); (4) preserving womenâs dignity (delivering high quality and respectful care); (5) provision of information (education about pregnancy and childbirth including environment in facility, labor processes/procedures, and the risks and benefits of both vaginal delivery and caesarean section). Conclusions Our study suggests, there are barriers to increasing demand for and satisfaction with vaginal birth, such as womenâs perceived sub-optimal quality of care during labor and birth, understaffed facilities that lack standard protocols and have limited physical space, and lack of privacy and dignity. The multifactorial nature of the increase of unnecessary Cesarean section calls for multicomponent interventions to revert this trend. These interventions need to address the health-systemsâ and health-facilitiesâ deficiencies behind womenâs preference for Cesarean section
Evaluation of sexual attitude and sexual function in menopausal age; a population based cross-sectional study
Background: Menopause and its physical, hormonal and psychosocial
changes could affect womenâs sexual function. There are
controversial results regarding relationship between sexual attitudes
and function. Objective: We aimed to evaluate sexual attitudes and
sexual function among Iranian menopausal age women. Materials and
Methods: This population based cross-sectional study was carried out on
225 menopausal women, aged 45-65 years. Based on a self-made
questionnaire data were collected about womenâs socio-demographic
characteristics, attitudes regarding sexuality and sexual function.
Data were analyzed using SPSS and sexual function was compared between
three groups of women who had positive, medium and negative attitudes
regarding sexuality. Results: The mean age of women was 53.11Âą4.56
years. Seventy percent of them had at least one sexual problem. Feeling
of dyspareunia was significantly different between three categories of
attitudes regarding sexuality (p=0.03). Comparing data obtained on
their attitudes, sexual desire, orgasm and dyspareunia demonstrated
significant differences (p=0.03, 0.04, and 0.04 respectively).
Conclusion: Attitude regarding sexual function has a great impact on
sexual activity of postmenopausal women that need to be considered in
their health care programming
Various screening and diagnosis approaches for gestational diabetes mellitus and adverse pregnancy outcomes: a secondary analysis of a randomized non-inferiority field trial
Introduction We evaluate which screening and diagnostic approach resulted in the greatest reduction in adverse pregnancy outcomes due to increased treatment.Research design and methods This study presents a secondary analysis of a randomized community non-inferiority trial conducted among pregnant women participating in the GULF Study in Iran. A total of 35â430 pregnant women were randomly assigned to one of the five prespecified gestational diabetes mellitus (GDM) screening protocols. The screening methods included fasting plasma glucose (FPG) in the first trimester and either a one-step or a two-step screening method in the second trimester of pregnancy. According to the results, participants were classified into 6 groups (1) First-trimester FPG: 100â126âmg/dL, GDM diagnosed at first trimester; (2) First trimester FPG: 92â99.9âmg/dL, GDM diagnosed at first trimester; (3) First trimester FPG: 92â99.9âmg/dL, GDM diagnosed at second trimester; (4) First trimester FPG: 92â99.9âmg/dL, healthy at second trimester; (5) First trimester FPG<92âmg/dL, GDM diagnosed at second trimester; (6) First trimester FPG<92âmg/dL, healthy at second trimester. For our analysis, we initially used group 6, as the reference and repeated the analysis using group 2, as the reference group. The main outcome of the study was major adverse maternal and neonatal outcomes.Results Macrosomia and primary caesarean section occurred in 9.8% and 21.0% in group 1, 7.8% and 19.8% in group 2, 5.4% and 18.6% in group 3, 6.6% and 21.5% in group 4, 8.3% and 24.0% in group 5, and 5.4% and 20.0% in group 6, respectively. Compared with group 6 as the reference, there was a significant increase in the adjusted risk of neonatal intensive care unit (NICU) admission in groups 1, 3, and 5 and an increased risk of macrosomia in groups 1, 2, and 5. Compared with group 2 as the reference, there was a significant decrease in the adjusted risk of macrosomia in group 3, a decreased risk of NICU admission in group 6, and an increased risk of hyperglycemia in group 3.Conclusions We conclude that screening approaches for GDM reduced the risk of adverse pregnancy outcomes to the same or near the same risk level of healthy pregnant women, except for the risk of NICU admission that increased significantly in groups diagnosed with GDM compared with healthy pregnant women. Individuals with slight increase in FPG (92â100âmg/dL) at first trimester, who were diagnosed as GDM, had an even increased risk of macrosomia in comparison to those group of women with FPG 92â100âmg/dL in the first trimester, who were not diagnosed with GDM, and developed GDM in second trimesterTrial registration IRCT138707081281N1 (registered: February 15, 2017)