Epidemiology of Hypertension in the Prefecture of Figuig, Morocco

BACKGROUND: Hypertension continues to be a public health problem with devastating consequences globally, particularly in developing countries where there is an acute paucity of hypertension data.The aim of this study was to describe the epidemiological, clinical, and treatment characteristics of hypertensive patients in the prefecture of Figuig, Morocco. METHODS: Retrospective analysis of hypertensive patients’ medical records from 2010 to 2020. The diagnosis, treatments, and complications were reported by physicians and cardiologists. Data analysis was made according to epidemiological, clinical complications, and treatments. RESULTS: Hypertension progressed from 871 cases in 2010 to 1785 cases in 2020 with an average annual incidence rate of 105.56/100,000 person-year, affecting more women than men (68% vs 32%). Hypertension was higher among rural residents compared to urban residents (54.0%vs 46%). Hypertension was noted in 65.4 % of patients aged 60+, and in 30.49% of patients aged 40-59. The incidence proportion of clinical complications is Ipcomplications=18.35/1000 person- year, principally cardiovascular diseases (45.42%), stroke (25.55%), retinopathy (17.98%) and nephropathy (10.41%). The most antihypertensive drugs used were Calcium channel blockers (33.39%), Angiotensin-converting enzyme inhibitors (21.13%), Angiotensin receptors blockers (21.21%), diuretics (19.4%), beta-blockers (5.38%) and central antihypertensive (10.46%) with an average coverage needs of treatments in the prefecture as (47.29%). CONCLUSION: Hypertension progresses gradually in the prefecture, higher among older individuals, women and rural residents. Large proportion of patients cannot find their treatments in health care structures which lead to poor blood pressure control, accelerating the appearance of complications

Système de reproduction dans une population humaine solée du Moyen Atlas du Maroc (population de Fritissa)

Le système de reproduction d¿une population humaine est déterminé par des variables socio-démographiques, l¿intérêt porté à l¿étude de ce système est justifié par le rôle que joue le choix du conjoint sur la structure génétique de la famille et sur l¿évolution du patrimoine héréditaire de la population . L¿objectif de ce travail est de déterminer le niveau d¿endogamie et de consanguinité dans une population rurale isolée (population de Fritissa au Maroc) qui est fragmentée en sous populations différentes suivant leurs origines lointaines. Les résultats de cette étude montrent un très fort taux d¿endogamie et de consanguinité selon l¿origine de la population (Arabe, Berbère, Chourfas ou migrants). Ainsi, l¿estimation du taux de consanguinité par isonymie et par consanguinité apparente sera discutée

Behavioral and electrophysiological study of phonological priming between bisyllabic spoken words.

Phonological priming between bisyllabic (CV.CVC) spoken items was examined using both behavioral (reaction times, RTs) and electrophysiological (event-related potentials, ERPs) measures. Word and pseudoword targets were preceded by pseudoword primes. Different types of final phonological overlap between prime and target were compared. Critical pairs shared the last syllable, the rime or the coda, while unrelated pairs were used as controls. Participants performed a target shadowing task in Experiment 1 and a delayed lexical decision task in Experiment 2. RTs were measured in the first experiment and ERPs were recorded in the second experiment. The RT experiment was carried out under two presentation conditions. In Condition 1 both primes and targets were presented auditorily, while in Condition 2 the primes were presented visually and the targets auditorily. Priming effects were found in the unimodal condition only. RTs were fastest for syllable overlap, intermediate for rime overlap, and slowest for coda overlap and controls that did not differ from one another. ERPs were recorded under unimodal auditory presentation. ERP results showed that the amplitude of the auditory N400 component was smallest for syllable overlap, intermediate for rime overlap, and largest for coda overlap and controls that did not differ from one another. In both experiments, the priming effects were larger for word than for pseudoword targets. These results are best explained by the combined influences of nonlexical and lexical processes, and a comparison of the reported effects with those found in monosyllables suggests the involvement of rime and syllable representations

Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients

Objective: To evaluate venous thromboembolism (VTE) risk in patients who underwent a major operation, including the use of, and factors influencing, American College of Chest Physicians-recommended types of VTE prophylaxis

Venous thromboembolism risk and prophylaxis in hospitalised medically ill patients The ENDORSE Global Survey

Limited data are available regarding the risk for venous thromboembolism (VIE) and VIE prophylaxis use in hospitalised medically ill patients. We analysed data from the global ENDORSE survey to evaluate VTE risk and prophylaxis use in this population according to diagnosis, baseline characteristics, and country. Data on patient characteristics, VIE risk, and prophylaxis use were abstracted from hospital charts. VTE risk and prophylaxis use were evaluated according to the 2004 American College of Chest Physicians (ACCP) guidelines. Multivariable analysis was performed to identify factors associated with use of ACCP-recommended prophylaxis. Data were evaluated for 37,356 hospitalised medical patients across 32 countries. VIE risk varied according to medical diagnosis, from 31.2% of patients with gastrointestinal/hepatobiliary diseases to 100% of patients with acute heart failure, active noninfectious respiratory disease, or pulmonary infection (global rate, 41.5%). Among those at risk for VTE, ACCP-recommended prophylaxis was used in 24.4% haemorrhagic stroke patients and 40-45% of cardiopulmonary disease patients (global rate, 39.5%). Large differences in prophylaxis use were observed among countries. Markers of disease severity, including central venous catheters, mechanical ventilation, and admission to intensive care units, were strongly associated with use of ACCP-recommended prophylaxis. In conclusion, VIE risk varies according to medical diagnosis. Less than 40% of at-risk hospitalised medical patients receive ACCP-recommended prophylaxis. Prophylaxis use appears to be associated with disease severity rather than medical diagnosis. These data support the necessity to improve implementation of available guidelines for evaluating VIE risk and providing prophylaxis to hospitalised medical patients