Numerical solutions of two-point boundary value problems in Chebyshev series

Series expressed in terms of Chebyshev polynomials are applied using Lie series to the iterative solution of ordinary differential equations. After a discussion of initial value problems, the method is then used to solve two-point boundary value problems and an improved method of shooting type is derived and tested

IMPROVING FRUIT SET, YIELD AND FRUIT QUALITY OF KHADRAWI DATE PALM CULTIVAR

This experiment was carried out during 2015 and 2016 experimental seasons to investigate the effect of spraying with moringa extract at 3%, garlic extract at 3% or ascorbic acid at 300 ppm on fruit set, yield and fruit quality of Khadrawi date palm cultivar. Anyhow, bunches were sprayed at three times (3 hours before pollination then 4 and 8 weeks after pollination). The present results indicated that spraying date palm bunches with moringa extract or garlic extract recorded the highest initial fruit set in the first and second seasons, respectively. As well as, moringa extract gave the highest fruit retention and yield in both seasons. In addition, all treatments improved some fruit physical characteristics i.e. fruit weight, flesh weight, fruit volume and fruit length compared to the control treatment in the two studied seasons. Also, results showed that moringa extract or ascorbic acid increased TSS%, total sugars % and reducing sugars % in both seasons compared to the control. Meanwhile, the lowest fibers % was obtained by garlic extract in the two seasons. Also, all treatments had no significant effect on total acidity % and tannins content in both seasons

Effects of Bivariation Viscosity and Magnetic Field on Trapping in a Uniform Tube with Peristalsis

In recent papers, Mehdi Lachiheb has considered fluid viscosity through a peristaltic tube and a channel as a function of the radial and axial components. This author discussed the trapping phenomenon at the centerline of a peristaltic tube and a channel, the pressure rise, and the drag (friction) forces without a magnetic field. Considering the importance of magnetohydrodynamic fluids in bioengineering and medical sciences, we discussed the effects of bivariation viscosity and magnetic field on the trapping phenomenon at the centerline, separated flow on the wall surface of the peristaltic tube, the drag (friction) forces, and the pressure rise. To solve the problem under low Reynolds and long wavelength assumptions, the velocity field and pressure gradient as functions of Hartmann number, amplitude ratio, viscosity parameter, and volume flow rate were obtained using the perturbation approach in terms of Hartmann number (M \u3c 1). The peristaltic pumping and augmented pumping regions were discussed through drag (friction) forces and the pressure rising. In addition, separation flow points on the surface of the wall were determined numerically

Facile synthesis of new pyrano[3,2-c]quinolones via the reaction of quinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile

Synthesis of heteroannulated pyrano[3,2-c] quinolones was established starting from the reaction of 4-hydroxyquinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile. Several conditions were carried out, and the corresponding product yields were illustrated. The neutral and non-polar condition was the best procedure for product formation. The structure of products was elucidated by NMR, IR, mass spectra, and elemental analysis. X-ray structure analysis was also used to elucidate the structure of the obtained products. The mechanism of products formation was also discussed.Peer reviewe

Sensitive Determination of Moxifloxacin HCl in Pharmaceuticals or Human Plasma Using Luminescence or Eye Vision

A new probe based on the complex of 1,2 dihydro-2-oxoquinoloine-4-carboxylic acid (DOCA) as a ligand with Europium (III) ion was developed for the quantitation of Moxifloxacin HCl (Moxi.HCl) in pharmaceuticals and human plasma using a luminescence method. The metal to ligand ratio of the complex is 1:2 as determined by a Job plot. The determination of Moxi.HCl is based on static quenching of the luminescence of the probe upon coordination of Moxi.HCl. The negative value for ΔG proves that this reaction is spontaneous. The calibration curve was constructed based on a Stern–Volmer equation and the quantitation range was 0.05–80 µg mL−1. This is low enough to determine the drug in blood plasma, even hours after administration, which is not feasible with the methods published so far. The LOD was 15 ng mL−1. The accuracy of the method was demonstrated by good recoveries of spiking experiments in tablets, ophthalmic eyedrops and human blood plasma, where the mean recovery was 99% with RSDs below 5%. The method was validated by closely matching concentrations of the drug found in all these real samples by HPLC. Additionally, Moxi.HCl can be assessed semi-quantitatively by eye vision upon excitation with a UV lamp at 365 nm by a gradual color shift from red to blue with increasing concentrations of Moxi.HCl

Changes in circulating microRNA levels can be identified as early as day 8 of pregnancy in cattle

<div><p>Poor reproductive performance remains a major issue in the dairy industry, with low conception rates having a significant impact on milk production through extended calving intervals. A major limiting factor is the lack of reliable methods for early pregnancy diagnosis. Identification of animals within a herd that fail to conceive within 3 weeks after insemination would allow early re-insemination and shorten calving intervals. In a previous study, we found an increase in plasma miR-26a levels in Day 16-pregnant relative to non-pregnant heifers, however changes in miRNA levels that early during pregnancy were very small which likely prevented the identification of robust biomarkers. In this study, we extended our analyses to a wider interval during pregnancy (Days 8 to 60, n = 11 heifers) with the rationale that this may facilitate the identification of additional early pregnancy miRNA biomarkers. Using small RNA sequencing we identified a total of 77 miRNAs that were differentially expressed on Day 60 relative to Day 0 of pregnancy. We selected 14 miRNAs for validation by RT-qPCR and confirmed significant differences in the expression of let-7f, let-7c, miR-30c, miR-101, miR-26a, miR-205 and miR-143 between Days 0 and 60. RT-qPCR profiling throughout Days 0, 8, 16 and 60 of pregnancy showed a distinct increase in circulating levels of miR-26a (3.1-fold, P = 0.046) as early as Day 8 of pregnancy. In summary, in contrast to earlier stages of pregnancy (≤ Day 24), marked differences in the levels of multiple miRNAs can be detected in circulation by Day 60 in cattle. Retrospective analyses showed miR-26a levels to be increased in circulation as early as Day 8, sooner than previously reported in any species, suggesting a biological role for this miRNA in the very early events of pregnancy.</p></div

Sociodemographic, Electrophysiological, and Biochemical Profiles in Children with Attention Deficit Hyperactivity Disorder and/or Epilepsy

Attention deficit hyperactivity disorder (ADHD) is among the most prevalent neurobehavioral disorders affecting children worldwide. The prevalence of ADHD is higher in children with epilepsy. Despite the plethora of conducted work, the precise cause of ADHD is not identified yet. We studied here the sociodemographic, clinical, electrophysiological, and biochemical profiles of children with ADHD, epilepsy, and ADHD with epilepsy. Subjects were divided into 4 groups (25 child/group): I—control, II—ADHD, III—epilepsy, and IV—ADHD with epilepsy. Male to female ratio was significantly (p<0.05) higher in the ADHD (3.1) and ADHD with epilepsy (2.1) groups when compared to the control (1.08) or epilepsy (1.08) groups. Positive family history was significantly evident in patients with epilepsy and ADHD with epilepsy, but not in the control or ADHD groups. Speech development was significantly delayed in the ADHD and ADHD with epilepsy groups. EEG abnormalities were detected in patients with ADHD (12%) and ADHD with epilepsy (68%). Focal frontal activities were significantly detectable in the ADHD (100%) and ADHD with epilepsy (77.8%) groups, whereas focal temporal activity was significantly present in the epilepsy (83.3%) group. Serum ferritin was significantly lower in the ADHD group (110.27 ± 6.64 ηg/ml) when compared to the control (134.23 ± 14.82 ηg/ml), epilepsy (159.66 ± 33.17 ηg/ml), and ADHD with epilepsy (203.04 ± 50.64 ηg/ml) groups. Serum zinc was significantly higher in the ADHD, epilepsy, and ADHD with epilepsy groups (236.63 ± 20.89, 286.74 ± 43.84, and 229.95 ± 67.34 μg/dl, respectively), when compared to the control group (144.21 ± 17.40 μg/dl). Serum adenosine deaminase was insignificantly different among the groups. Our results indicate that gender and family history are significant moderators in the aetiology of ADHD and epilepsy or their comorbidity. We also demonstrated that EEG could be central in the assessment of ADHD with epilepsy cases. Serum ferritin and zinc alteration may contribute significantly in ADHD and epilepsy pathophysiology