The Use of MotusBASEBALL For Pitch Monitoring and Injury Prevention

Introduction: MotusBASEBALL (MOTUS) has proven to be a reliable and accurate method for evaluating the multifactorial kinesiology involved with pitching. We sought to review the use of MOTUS in assessment of pitching parameters and identify its practicality as an injury prevention tool across the literature. Methods: A systemic review of the literature was preformed, using key words such as MOTUS, baseball, pitcher, sensor and arm sleeve, identifying 77 total articles. Inclusion criteria entailed original articles that used MOTUS and studied baseball pitchers across any level of sport. Results: A total of 13 articles met the inclusion criteria, producing a sample of 493 male athletes with a mean age of 18.7. Uniformly across studies, elbow torque was a primary metric and was observed in relation to a wide range of variables, such as pitch type, height, weight and arm length. Additionally, MOTUS was able to detect several other pitching metrics, such as arm speed, shoulder rotation and arm slot, displaying a wide range of capabilities. Conclusion: We suspect MOTUS technology could become a significant tool for observing pitching mechanics in real time, as well as an injury prevention tool to be used by players, coaches and trainers across all levels of baseball

Can Opioids be Eliminated After Arthroscopic Meniscus Surgery? A Prospective Randomized Controlled Trial

Purpose: To compare a multimodal nonopioid pain protocol to traditional opioid medication in controlling postoperative pain following arthroscopic meniscal surgery. Methods: Ninety-nine patients undergoing primary meniscectomy or meniscal repair were assessed for participation. A prospective randomized control trial was performed in accordance with the Consolidated Standards of Reporting Trials 2010 (CONSORT) statement. The two arms of the study included a multimodal non-opioid analgesic protocol and a standard opioid regimen with a primary outcome of postoperative pain level (visual analog scale) for 10 days. Secondary outcomes included patient reported outcomes, complications and patient satisfaction. Randomization was achieved using a random number generator. Patients were not blinded. Data collection was done by a blinded observer. Results: A total of 61 patients were analyzed with 30 randomized to the opioid regimen, and 31 randomized to the non-opioid regimen. Patients receiving the nonopioid regimen demonstrated non-inferior VAS scores compared to patients who received opioid pain medication (p\u3e0.05) No significant differences were found in preoperative (opioid: 58.9 ± 7.0; nonopioid: 58.2 ± 5.5, p = 0.724) nor postoperative (opioid: 59.8 ± 6.5; nonopioid: 54.9 ± 7.1, p = 0.064) PROMIS-Pain Interference Short Form scores. No difference was found in recorded side effects between both groups: constipation, nausea, diarrhea, upset stomach, and drowsiness (p \u3c 0.05). Conclusion: This study found that multimodal nonopioid pain protocol provided equivalent pain control and patient outcomes following primary meniscus surgery while having an equivalent side effect profile. All patients reported satisfaction with their pain management without requiring emergency opioid analgesia

Career Longevity and Performance Following Shoulder Instability in National Football League Athletes

Purpose: To investigate the career longevity, game utilization and performance of National Football League (NFL) athletes following glenohumeral instability events treated operatively versus nonoperatively. Methods: Public resources identified NFL players who sustained a shoulder instability event from 2000-2019. Players with prior shoulder instability, without NFL experience before injury, or who did not return to play (RTP) after injury were excluded. Demographic information, utilization (games and seasons), and season approximate value (SAV) statistics were recorded one year prior to injury and three years following return to play (RTP). Statistical analysis compared utilization and SAV following RTP for athletes managed operatively versus nonoperatively. Results: Ninety-seven NFL players who sustained their first instability event while playing in the NFL were identified, 91 of whom RTP (93.8%). Quarterbacks were significantly more likely to undergo immediate surgical management compared to other positions (P=.023). Final analysis included 58 players managed operatively and 33 players managed nonoperatively by the end of the index season. Players treated operatively played in significantly more seasons following RTP during their remaining career (4.1±2.7 vs. 2.8±2.5 seasons; P=.015). There were no differences in games played or started, offensive or defensive snap count percentage, or performance (SAV) before and after injury when compared between cohorts (P\u3e.05). Following surgical stabilization, time to RTP (36.62±10.32 vs. 5.43±12.33 weeks, P Conclusions: Athletes who RTP in the NFL following a shoulder instability injury do so with similar workload and performance irrespective of surgical or non-surgical management. While nonoperative treatment is associated with faster return to play, operative management is associated with fewer recurrent instability events, greater time between recurrent instability events, and greater career longevit

Stream-Based Authentication Strategy Using IoT Sensor Data in Multi-homing Sub-aqueous Big Data Network

Big data analytics has addressed many in-place and remote network issues in a sub-aqueous distributed computing environment. Recently, a new phenomenon is introduced in the data analytics clusters that focus on multi-homing network connectivity procedures among off-ground multiple nodes of the large-scale on-running wireless industrial applications. In this way, the clusters perform multi-layer cross-connected task processing among various networks simultaneously and perform stream based data block placement over multiple nodes in a sequential order. This satisfies the procedural performance of the cluster; however, security remains an open issue in it because of unavailability of inter-network data block processing authorization. In this paper, we propose a stream based authentication mechanism, that specifically addresses security concerns of multi-homing sub-aqueous big data networks and presents a key authorization infrastructure that performs a proper handing taking among multiple off-ground Datanodes before an inter-network data block exchange. The simulation results depict that our approach increases multi-homing network compatibility and reliability while processing a data block in the sub-aqueous distributed computing environment

On some fixed point theorems under (α,ψ,ϕ) -contractivity conditions in metric spaces endowed with transitive binary relations

After the appearance of Nieto and Rodríguez-López’s theorem, the branch of fixed point theory devoted to the setting of partially ordered metric spaces have attracted much attention in the last years, especially when coupled, tripled, quadrupled and, in general, multidimensional fixed points are studied. Almost all papers in this direction have been forced to present two results assuming two different hypotheses: the involved mapping should be continuous or the metric framework should be regular. Both conditions seem to be different in nature because one of them refers to the mapping and the other one is assumed on the ambient space. In this paper, we unify such different conditions in a unique one. By introducing the notion of continuity of a mapping from a metric space into itself depending on a function α, which is the case that covers the partially ordered setting, we extend some very recent theorems involving control functions that only must be lower/upper semi-continuous from the right. Finally, we use metric spaces endowed with transitive binary relations rather than partial orders.This article was funded by the Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah. N Shahzad acknowledges with thanks DSR for financial support. A-F Roldán-López-de-Hierro is grateful to the Department of Quantitative Methods for Economics and Business of the University of Granada. The same author has been partially supported by Junta de Andalucía by project FQM-268 of the Andalusian CICYE

Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression.

Stressful life events produce a state of vulnerability to depression in some individuals. The mechanisms that contribute to vulnerability to depression remain poorly understood. A rat model of intense stress (social defeat (SD), first hit) produced vulnerability to depression in 40% of animals. Only vulnerable animals developed a depression-like phenotype after a second stressful hit (chronic mild stress). We found that this vulnerability to depression resulted from a persistent state of oxidative stress, which was reversed by treatment with antioxidants. This persistent state of oxidative stress was due to low brain-derived neurotrophic factor (BDNF) levels, which characterized the vulnerable animals. We found that BDNF constitutively controlled the nuclear translocation of the master redox-sensitive transcription factor Nrf2, which activates antioxidant defenses. Low BDNF levels in vulnerable animals prevented Nrf2 translocation and consequently prevented the activation of detoxifying/antioxidant enzymes, ultimately resulting in the generation of sustained oxidative stress. Activating Nrf2 translocation restored redox homeostasis and reversed vulnerability to depression. This mechanism was confirmed in Nrf2-null mice. The mice displayed high levels of oxidative stress and were inherently vulnerable to depression, but this phenotype was reversed by treatment with antioxidants. Our data reveal a novel role for BDNF in controlling redox homeostasis and provide a mechanistic explanation for post-stress vulnerability to depression while suggesting ways to reverse it. Because numerous enzymatic reactions produce reactive oxygen species that must then be cleared, the finding that BDNF controls endogenous redox homeostasis opens new avenues for investigation