Controlled modulation of 1D ZnO nano/micro structures: Evaluation of the various effects on the photocatalytic activity

Effects of the concentration, temperature and precursor type on the fabrication of the elongated ZnO nano/micro structures were comprehensively investigated. Analytical investigations such as SEM and statistical analysis of the elongated ZnO nano/micro structures provided wide information about the growth behavior and final geometries. Different temperatures for the 1 D ZnO formation clearly revealed that hexagonally grown ZnO nanorods were obtained. Especially low crystal diffraction characteristics at low temperature (55 °C) implied that ZnO nano/micro rod formation requires some minimum conditions for the formation of an efficient photocatalyst. All XRD investigations together with SEM and TEM supported the ligand ordered elongation conducted by diverse beginning concentrations. Since temperature found as a highly dominant actor for morphology and surface sequence as manifested in crystallinity, morphology and photocatalytic results, we have systematically summarized the growth conditions of the ZnO nano/micro rods from same precursor. © 2017 Elsevier Lt

Turner syndrome and associated problems in turkish children: A multicenter study

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

Controlled modulation of 1D ZnO nano/micro structures: Evaluation of the various effects on the photocatalytic activity

Effects of the concentration, temperature and precursor type on the fabrication of the elongated ZnO nano/micro structures were comprehensively investigated. Analytical investigations such as SEM and statistical analysis of the elongated ZnO nano/micro structures provided wide information about the growth behavior and final geometries. Different temperatures for the 1 D ZnO formation clearly revealed that hexagonally grown ZnO nanorods were obtained. Especially low crystal diffraction characteristics at low temperature (55 °C) implied that ZnO nano/micro rod formation requires some minimum conditions for the formation of an efficient photocatalyst. All XRD investigations together with SEM and TEM supported the ligand ordered elongation conducted by diverse beginning concentrations. Since temperature found as a highly dominant actor for morphology and surface sequence as manifested in crystallinity, morphology and photocatalytic results, we have systematically summarized the growth conditions of the ZnO nano/micro rods from same precursor. © 2017 Elsevier Lt

Genotype–phenotype correlation, gonadal malignancy risk, gender preference, and testosterone/dihydrotestosterone ratio in steroid 5-alpha-reductase type 2 deficiency: a multicenter study from Turkey

PubMed ID: 30132287Background: Studies regarding genetic and clinical characteristics, gender preference, and gonadal malignancy rates for steroid 5-alpha-reductase type 2 deficiency (5?-RD2) are limited and they were conducted on small number of patients. Objective: To present genotype–phenotype correlation, gonadal malignancy risk, gender preference, and diagnostic sensitivity of serum testosterone/dihydrotestosterone (T/DHT) ratio in patients with 5?-RD2. Materials and methods: Patients with variations in the SRD5A2 gene were included in the study. Demographic characteristics, phenotype, gender assignment, hormonal tests, molecular genetic data, and presence of gonadal malignancy were evaluated. Results: A total of 85 patients were included in the study. Abnormality of the external genitalia was the most dominant phenotype (92.9%). Gender assignment was male in 58.8% and female in 29.4% of the patients, while it was uncertain for 11.8%. Fourteen patients underwent bilateral gonadectomy, and no gonadal malignancy was detected. The most frequent pathogenic variants were p.Ala65Pro (30.6%), p.Leu55Gln (16.5%), and p.Gly196Ser (15.3%). The p.Ala65Pro and p.Leu55Gln showed more undervirilization than the p.Gly196Ser. The diagnostic sensitivity of stimulated T/DHT ratio was higher than baseline serum T/DHT ratio, even in pubertal patients. The cut-off values yielding the best sensitivity for stimulated T/DHT ratio were ? 8.5 for minipuberty, ? 10 for prepuberty, and ? 17 for puberty. Conclusion: There is no significant genotype–phenotype correlation in 5?-RD2. Gonadal malignancy risk seems to be low. If genetic analysis is not available at the time of diagnosis, stimulated T/DHT ratio can be useful, especially if different cut-off values are utilized in accordance with the pubertal status. © 2018, Italian Society of Endocrinology (SIE).32015Funding This work was supported financially by the Turkish Pediatric Endocrinology and Diabetes Society (Grant number: 032015). -