439 research outputs found

    Climate Change, Markets, and Technology

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    Environmental Economics and Policy, Resource /Energy Economics and Policy, Q15, Q25, Q38,

    Economic Analysis of the 2016 California Drought on Agriculture: A report for the California Department of Food and Agriculture

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    UC Davis researchers forecast the socio-economic effects of the drought on California agriculture for 2014 and beyond. Economists use computer models and the latest estimates of water deliveries, well-pumping capacities and acres fallowed. The researchers exploit new satellite remote-sensing technologies to estimate fallowed acreage as the drought unfolds.UC Davis researchers forecast the socio-economic effects of the drought on California agriculture for 2014 and beyond. Economists use computer models and the latest estimates of water deliveries, well-pumping capacities and acres fallowed. The researchers exploit new satellite remote-sensing technologies to estimate fallowed acreage as the drought unfolds

    Study on the effects of using a carbon dioxide atmosphere on the properties of vine shoots-derived biochar

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    This study analyzes the effects of using a different atmosphere (pure N2 or pure CO2) at two levels of absolute pressure (0.1 and 1.1 MPa) on the pyrolysis of vine shoots at a constant peak temperature of 600 °C. Recycling CO2 from residual flue gases into the pyrolysis process may be economically beneficial, since CO2 can replace the use of an expensive N2 environment. In addition, the use of a moderate pressure (e.g., 1.1 MPa) can result in higher carbonization efficiencies and an improvement in the pyrolysis gas (in terms of yield and composition). Results from our study suggest that the use of CO2 instead of N2 as pyrolysis environment led to similar carbonization efficiencies (i.e., fixed-carbon yields) and mass yields of biochar. The chemical properties related to the potential stability of biochar (i.e., fixed-carbon content and molar H:C and O:C ratios) were very similar for both pyrolysis atmospheres. Under an atmosphere of CO2, the yield of produced CO2 was drastically decreased at the expense of an increase in the yield of CO, probably as a consequence of the promotion of the reverse Boudouard reaction, especially at high pressure. The enhanced reverse Boudouard reaction can also explain the relatively high BET specific surface area and the macro-porosity development observed for the biochar produced under a CO2 environment at 1.1 MPa. In summary, the pressurized pyrolysis of biomass under an atmosphere of CO2 appears as a very interesting route to produce highly stable and porous biochars and simultaneously improving the yield of CO

    Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naïve pluripotency

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    Clusters of enhancers, referred as to super-enhancers (SEs), control the expression of cell identity genes. The organisation of these clusters, and how they are remodelled upon developmental transitions remain poorly understood. Here, we report the existence of two types of enhancer units within SEs typified by distinctive CpG methylation dynamics in embryonic stem cells (ESCs). We find that these units are either prone for decommissioning or remain constitutively active in epiblast stem cells (EpiSCs), as further established in the peri-implantation epiblast in vivo. Mechanistically, we show a pivotal role for ESRRB in regulating the activity of ESC-specific enhancer units and propose that the developmentally regulated silencing of ESRRB triggers the selective inactivation of these units within SEs. Our study provides insights into the molecular events that follow the loss of ESRRB binding, and offers a mechanism by which the naive pluripotency transcriptional programme can be partially reset upon embryo implantation

    Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency

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    Clusters of enhancers, referred as to super-enhancers (SEs), control the expression of cell identity genes. The organisation of these clusters, and how they are remodelled upon developmental transitions remain poorly understood. Here, we report the existence of two types of enhancer units within SEs typified by distinctive CpG methylation dynamics in embryonic stem cells (ESCs). We find that these units are either prone for decommissioning or remain constitutively active in epiblast stem cells (EpiSCs), as further established in the peri-implantation epiblast in vivo. Mechanistically, we show a pivotal role for ESRRB in regulating the activity of ESC-specific enhancer units and propose that the developmentally regulated silencing of ESRRB triggers the selective inactivation of these units within SEs. Our study provides insights into the molecular events that follow the loss of ESRRB binding, and offers a mechanism by which the naive pluripotency transcriptional programme can be partially reset upon embryo implantation

    Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults : EDNA diagnostic accuracy study

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    Funding This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 26, No. 8. See the NIHR Journals Library website for further project information.Peer reviewedPublisher PD

    Evaluation of the oxidative stability of Chipotle chili (Capsicum annuum L.) oleoresins in avocado oil

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    Capsicum annuum L. (Chipotle chili) is a natural source of bioactive metabolites with antioxidant properties. The objective of this research was to obtain and characterize the oxidative stability under storage of Chipotle chili oleoresins extracted with cold-pressed avocado oil. The most efficient conditions obtained to extract carotenoids and phenolic compounds were at 1:3 ratio (chipotle chili: avocado oil; w:v) at room temperature in darkness during 48 h. At the end of the harshest conditions (45 °C, 30 days), the extracts were stable to lipid oxidation with a final Totox value of 27.34, a carotenoid preservation of 85.6%, antioxidant activity retention of 80.66% and a color change (ΔE) of 1.783. The kinetic constants obtained were higher for peroxide formation than for carotenoid degradation. The oleoresins obtained could be considered an economic and sustainable alternative to extract carotenoids with good oxidation stability that could be used in foodstuffs
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