Right Atrial Lipoma Resection And Partial Reconstruction Using Bovine Pericardium [ressecção De Um Lipoma De átrio Direito E Reconstrução Parcial Com Pericárdio Bovino]

The primary heart tumors have an incidence varying from 0.001% to 0.28% of all tumors, reported in necropsies series. Lipoma consists of a benign tumour corresponding to about 8% of all primary heart tumors. When present, the symptoms are related to the size and location of such tumor. We report a case of a 27-year-old man with a lipoma in the right atrium who underwent surgical treatment with tumor resection and partial reconstruction of the right atrium using bovine pericardium.242239241Silveira, W.L., Nery, W.M., Soares, E.C.G., Leite, A.F., Nazzetta, H., Batista, M.A.L., Lipoma de átrio direito (2001) Arq Bras Cardiol, 77 (4), pp. 361-4Heath, D., Pathology of cardiac tumors (1968) Am J Cardiol., 21 (3), pp. 315-27Fernandes, F., Soufen, H.N., Lanni, B.M., Arteaga, E., Ramires, F.J.A., Mady, C., Neoplasias primárias do coração. Apresentação clínica e histológica de 50 casos (2001) Arq Bras Cardiol., 76 (3), pp. 231-4Silverman, N.A., Primary cardiac tumors (1980) Ann Surg., 191 (2), pp. 127-38Lima, I.P.R.L., Crotti II, P.L.R., Tumores cardíacos malignos (2004) Rev Bras Cir Cardiovasc, 19 (1), pp. 64-73Lion, M.F., Moreira, A.E.L.C., Silva, M.V.B., Inversão de auricular esquerda por lipoma epicárdico. Comportamento atípico de um tumor levando a obstrução de veias pulmonares (1994) Arq Bras Cardiol., 62 (3), pp. 207-10Arslan, S., Gundogdu, F., Acikel, M., Kantarci, A.M., Asymptomatic cardiac lipoma originating from the interventricular septum diagnosed by multi-slice computed tomography (2007) Int J Cardiovasc Imaging, 23 (2), pp. 277-9Mousseaux, E., Idy-Peretti, I., Bittoun, J., Diebold, B., Paulylaubry, C., Carpentier, A., MR tissue characterization of a right atrial mass: Diagnosis of a lipoma (1992) J Comput Assist Tomogr., 16 (1), pp. 148-51Rubino, M., Hamad, A.M., Rea, F., Gerosa, G., Reconstruction of the right atrium with pulmonary artery homograft after resection of right atrial lipomatosis (2007) Interact Cardiovasc Thorac Surg., 6 (6), pp. 826-

β-thalassemia Intermedia In A Brazilian Patient With - 101 (c > T) And Codon 39 (c > T) Mutations

Context: We verified molecular alterations in a 72-year-old Brazilian male patient with a clinical course of homozygous β-thalassemia intermedia, who had undergone splenectomy and was surviving without regular blood transfusions. The blood cell count revealed microcytic and hypochromic anemia (hemoglobin = 6.5 g/dl, mean cell volume = 74 ft, mean cell hemoglobin = 24 pg) and hemoglobin electrophoresis showed fetal hemoglobin = 1.3%, hemoglobin A 2 = 6.78% and hemoglobin A = 79.4%. Objective: To identify mutations in a patient with the symptoms of β-thalassemia intermedia. Design: Molecular inquiry into the mutations possibly responsible for the clinical picture described. Setting: The structural molecular biology and genetic engineering center of the Universidade Estadual de Campinas, Campinas, Brazil. Procedures: DNA extraction was performed on the patient's blood samples. The polymerase chain reaction (PCR) was done using five specific primers that amplified exons and the promoter region of the β globin gene. The samples were sequenced and then analyzed via computer programs. Results: Two mutations that cause the disease were found: -101 (C > T) and codon 39 (C > T). Conclusions: This cases represents the first description of -101 (C > T) mutation in a Brazilian population and it is associated with a benign clinical course.12112830Baysal, E., Carver, M.F.H., The beta and delta-thalassemia repository (1995) Hemoglobin., 19 (3-4), pp. 213-236Zago, M.A., Costa, F., Bottura, C., Beta-thalassemia in Brazil (1981) Braz. J. Med. Biol. Res., 14 (6), pp. 383-388Ewing, B., Green, P., Base-calling of automated sequencer traces using Phred. II Error probabilities (1998) Genome Res., 8 (3), pp. 186-194Green, P., (2002), http://bozeman.genome.washington.edu/phrap.docs/phrap.html, The Phred/Phrap/Consed System Home Page. Phrap Assembler. Available at URL September 30Gordon, D., Abajian, C., Green, P., Consed: A graphical tool for sequence finishing (1998) Genome Res., 8 (3), pp. 195-20

Tratamento de um paciente acometido por traumatismo dental por meio de uma abordagem multidisciplinar e interdisciplinar

Este trabalho tem por objetivo descrever o caso clínico de um paciente atendido no Serviço de Trauma Dental da Faodo/UFMS com múltiplos comprometimentos dentais causados por trauma, com uma abordagem multidisciplinar e interdisciplinar. Este relato de caso tem o objetivo apresentar o tratamento realizado em um paciente acometido por trauma dental nos dentes 11, 12, 21 e 22, com necessidade de integrar as especialidades de endodontia, dentística, prótese, ortodontia, periodontia, cirurgia, implantodontia e nutrição. O paciente chegou ao STD após dois dias de ter sofrido acidente automobilístico. Ao exame clínico e radiográfico foi constatado o envolvimento dos dentes 11- fratura de esmalte e dentina (FED) sem comprometimento pulpar,12- fratura corono-radicular com comprometimento pulpar, 21- FED com comprometimento pulpar e fratura radicular e 22- concussão. Como tratamento emergencial realizou-se a pulpectomia nos dentes 12 e 21 e proteção pulpar indireta no 11. Em seguida, o plano de tratamento proposto foi a realização de cirurgia para acesso e colagem de fragmento no 21, restauração em resina composta no 11 e extrusão ortodôntica no 12, com fibrotomia concomitante, para realização de coroa unitária posteriormente. Devido a uma fratura radicular no dente 21, detectada durante a extrusão ortodôntica, foi indicada exodontia com instalação imediata de implante e prótese provisória. O dente 22 não necessitou de intervenção, apenas proservação. Por se tratar de um caso de traumatismo dental o paciente continua sob proservação.    Palavras-chave: Endodontia.  Dentística.  Saúde coletiva.&nbsp

The production of knowledge through religious and social media infrastructure : world making practices among Brazilian Pentecostals

Following Robertson’s discussions on epistemic capital, the article analyses worldmaking procedures being used by members of one of the biggest neo-Pentecostal churches in Brazil – Igreja Universal do Reino de Deus. According to the popular narrative, social media, especially WhatsApp groups, contributed in a crucial way to the spread of sets of conspiracy theories aimed to question “established narratives” and creating an image of Jair Bolsonaro, currently the president of Brazil, as the sole hero (“the messiah” and “the myth”) fighting against the “corrupted” Brazilian state and the “globalist/communist cabal.” The article discusses interactions between members of so-called families created by the Igreja Universal do Reino de Deus. These families could have between a few or around one hundred members, and they are in regular communication (at least a few times per day) through WhatsApp. Most members of one family do not live in walking proximity; therefore, using WhatsApp is often the primary way they interact. The article puts families into a broader context of the media ecosystem owned or influenced by Igreja Universal do Reino de Deus and contextualizes the church as a religious “infrastructure of knowing.” The article discusses sources of legitimization of particular knowledge produced and mediated between families. The article argues that communication in families contributes to the creation of unique epistemic tools crucial in re-creating individual worldviews of members Igreja Universal do Reino de Deus

Avaliação da contraimunoeletroforese com antígenos dos sorovars icterohaemorrhagiae E patoc no diagnóstico sorológico da leptospirose humana

Avaliou-se o desempenho da contraimunoeletroforese (CIE) no diagnóstico sorológico da leptospirose humana utilizando três tipos de antígenos derivados da L. interrogans sorovar icterohaemorrhagiae e do sorovar patoc da L. biflexa. Comparou-se os resultados obtidos na CIE com a prova de referência a soroaglutinação microscópica (SAM). Soros pareados de 135 pacientes com leptospirose foram subdivididos em 4 grupos de acordo com os resultados da SAM. Como controle coletou-se sangue de 69 indivíduos sadios. A concordância entre as duas técnicas variou de 92,64 a 94,11%. Os resultados obtidos pela CIE com os antígenos do sorovar icterohaemorrhagiae foram mais favoráveis do que aqueles derivados do patoc. Ressaltam-se as características de elevada sensibilidade detectando anticorpos antileptospiras mais precocemente do que a microaglutinação. As características encontradas no presente estudo credenciam o emprego da CIE como um método útil e prático para o diagnóstico da leptospirose humana na fase aguda da doença.Counterimmunoelectrophoresis (CIE) was applied on paired sera from 135 pacients with leptospirosis and on 69 sera from a control group. The sera from pacients were subdivided in 4 groups according to the results obtained by the Microscopic Agglutination Test (MAT). The first samples sera from 58 pacientes were non reagent by MAT. Six monthly samples of sera were taken from 7 patients to follow-up and to determine the level of agglutinin and precipitin antibodies present using MAT and CIE. Serovars icterohaemorrhagie and patoc were used as antigens. Three types of antigens were compared, 1) Triton-X-100 extracted; 2) heat extacted and 3) a pool of them. The CIE using icterohaemorrhagiae derivated antigens types agreed with MAT in 92.64, 92.64 and 94.11% of the leptospirosis sera. The patoc antigens types reacted with the control group in 7.24, 86.95 and 84.05% of the samples, and consequently were eliminated from the present study. The icterohaemorrhagiae CIE reaction become positive earlier than MAT negative sera, and reverted to negative earlier in the follow-up samples from the pacients. The CIE was sensitive and specific, gave rapid results and was easy to perform

Genetic divergence of soybean genotypes in relation to grain components

ABSTRACT: The objective of this paper was to estimate the genetic divergence among 49 soybean ( Glycine max L. Merrill .) genotypes to assist grain quality-focused breeding programs in the choice of progenitors. The genetic divergence was estimated using the Mahalanobis generalized distance from the percentages of protein, oil, and fatty acids oleic, linoleic and linolenic after cultivation of genotypes in different environments. Genotypes were grouped by agglomerative methods and the two and three-dimensional projections of the distance matrix were obtained. The average protein and oil contents in the four environments ranged from 34.25 to 45.18% and from 16.48 to 23.01%, respectively. The average contents of the fatty acids oleic, linoleic and linolenic ranged from 20.2 to 42.41%, from 44.17 to 63.18%, and from 5.89 to 10.39%, respectively. The genetic distances ranged from 0.11 to 251.02 and indicated genetic variability among the accessions. The most divergent pair of accessions was PI417360/CD01RR8384, followed by PI417360/B3PTA213-3-4 and PI417360/BARC-8. The most similar par of accessions was CS3032PTA276-1-2/CS3032PTA190-5-1, followed by UFV18/M-SOY8914 and BRSMG Garantia/CD983321RR. In this study we indicated as promising in terms of genetic variability the hybridizations involving BARC-8, CD2013PTA, CD01RR8384, CS303TNKCA, PI181544, and PI417360. Among these genotypes we can stand out BARC-8 and CD2013PTA, with protein contents above 43%, and CD01RR8384 and CS303TNKCA, with oil contents above 20%. The use of these genetically divergent genotypes and with high phenotypic means in future crosses should produce desirable recombinants for grain quality