69 research outputs found
Saúde dos trabalhadores de enfermagem e a segurança do paciente: o olhar de gerentes de enfermagem*
- Author
- Alves PC
- Ana Claudia Alcantara Garzin
- Baptista PCP
- Batista JM
- Campos GWS
- Capalbo C
- Carugno M
- Coggon D
- Ferraz CA
- Gartner FR
- Girondi JBR
- Gurgueira GP
- Gärtner FR
- LaMontagne AD
- Leite PC
- Marcelo Pustiglione
- Marta Maria Melleiro
- Mininel VA
- Mininel VA
- Mininel VA
- Mirian Cristina dos Santos Almeida
- Osmo AA
- Patricia Campos Pavan Baptista
- Ratier APP
- Scalco SV
- Schütz A
- Schütz A
- Silva SM
- Souza NSS
- Stansfeld S
- Vanda Elisa Andres Felli
- Wagner HR
- Zeferino MT
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Bioética e saúde coletiva: convergências epistemológicas
- Author
- Almeida Filho N
- Almeida Filho N
- Almeida Filho N
- Almeida Filho N
- Bachelard G
- Bourdieu P
- Callahan D
- Camargo Júnior KR
- Campos GWS
- Carson RA
- Conill SJ
- Cortina A
- Cunha GT
- Elma Lourdes Campos Pavone Zoboli
- Gadamer HG
- Gadamer HG
- Gracia D
- Gracia D
- Jose Roque Junges
- Junges JR
- Leder D
- Moore GE
- Morin E
- Morin E
- Morin E
- Morin E
- Morin E
- Nicolescu B
- Nunes ED
- Paim JS
- Potter VR
- Rozemberg B
- Samaja JA
- Samaja JA
- Santos BS
- Schramm FR
- Schramm FR
- Singer P
- Sotolongo PL
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Towards a Unified Theory of Health-Disease: I. Health as a complex model-object
- Author
- Albrecht G
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Almeida-Filho N
- Barondess JA
- Bhaskar R
- Bibeau G
- Bibeau G
- Boorse C
- Boorse C
- Boorse C
- Boulding K
- Bowen E
- Breslow L
- Bunge M
- Callahan D
- Campos T
- Canguilhem G
- Canguilhem G
- Castiel LD
- Clavreuil J
- Coelho MTAD
- Corin E
- Delattre P
- Donenberg GR
- Dubos RJ
- Edmonds B
- Engelhardt Jr HT
- Fedoryka K
- Fettke P
- Gadamer HG
- Gammelgaard A
- Gatrell AC
- Godfrey-Smith P
- Goenner HFM
- Hammond D
- Hansen NB
- Huber M
- Karnopp DC
- Kleinman A
- Kleinman A
- Krieger N
- Larson JS
- Levine S
- Mezzich J
- Minsky M
- Morin E
- Morin E
- Naomar Almeida-Filho
- Nietzsche FW
- Nordenfelt L
- Poundstone KE
- Richardson KA
- Root-Bernstein RS
- Sadegh-Zadeh K
- Samaja J
- Samaja J
- Saracci R
- Schramm FR
- Stempsey WE
- Strogatz SH
- Veinot T
- Von Bertalanffy L
- Weed DL
- Wulff HR
- Young A
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
2 nd Brazilian Consensus on Chagas Disease, 2015
- Author
- Abad-Franch F
- Abad-Franch F
- Abad-Franch F
- Abad-Franch F
- Abad-Franch F
- Abílio Augusto Fragata Filho
- Acquatella H
- Akhavan D
- Alberto Novaes Ramos Jr.
- Alejandro Luquetti
- Alejandro Marcel Hasslocher-Moreno
- Alessandra Viana Cardoso
- Almeida EA
- Almeida EA
- Almeida EA
- Almeida EA
- Almeida-Filho OC
- Altclas J
- Altclas JD
- Alves RM
- Ana Maria Jansen
- Ana Yecê das Neves Pinto
- Andrade AL
- Andrade SG
- Andréa Silvestre de Sousa
- Angheben A
- Anis Rassi
- Anis Rassi Jr.
- Antonio Walter Ferreira
- Antônio Carlos Silveira
- Barcán L
- Baroldi G
- Barreto ML
- Bern C
- Bern C
- Bern C
- Bern C
- Bern C
- Bestetti RB
- Bestetti RB
- Bestetti RB
- Bitto C
- Bocchi EA
- Bocchi EA
- Bocchi EA
- Brener Z
- Brener Z
- Britto CC
- Brutus L
- Brücher BL
- Bua J
- Buekens P
- Camargo ME
- Camargo ME
- Camargo ME
- Camargo ME
- Campos SV
- Cançado JR
- Carlier Y
- Carlier Y
- CarlierI Y
- Carrasco HA
- Carvalho VB
- Castro AM
- Castro CN
- Castro I
- Cerisola JA
- Cerisola JA
- Chagas C
- Chiale PA
- Chiari E
- Chiari E
- Chiari E
- Chippaux JP
- Constança Felícia De Paoli de Carvalho Britto
- Cordova E
- Coura JR
- Coura JR
- Coura JR
- Coura JR
- Coura JR
- Coura JR
- Coura JR
- Cunha GP
- D'Albuquerque LA
- Dalmo Correia
- Davila DF
- Dayse Elisabeth Campos
- De Rissio AM
- Del Castilho M
- Dias E
- Dias JC
- Dias JC
- Dias JC
- Dias JC
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JCP
- Dias JP
- Divina Seila de Oliveira Marques
- Drumond JAG
- Duhamel B
- Egler Chiari
- Eliane Dias Gontijo
- Eliane Furtado Moreira
- Eliane Lages Silva
- Eros Antonio de Almeida
- Fabbro DL
- Fabiane Scalabrini Pinto
- Ferguson MK
- Fernando Abad-Franch
- Ferreira AW
- Ferreira HO
- Ferreira HO
- Ferreira MS
- Fonseca FM
- Fragata Filho AA
- França LCM
- Freilij H
- Freitas H
- Freitas VL
- Gallerano RH
- Garcia S
- Garzon SA
- Gebrekristos HT
- Glaucia Manzan Queiroz Andrade
- Gontijo ED
- González-Tomé MI
- Guariento ME
- Heller E
- Herwaldt BL
- Higuchi ML
- Higuchi ML
- Higuchi ML
- Hijar G
- Hotez PJ
- Hotez PJ
- Howard EJ
- Ianni BM
- Inoue H
- Joffre Marcondes de Rezende
- José Antonio Marin-Neto
- José Renan da Cunha Melo
- José Rodrigues Coura
- João Carlos Pinto Dias
- Junqueira AC
- Jörg ME
- Júnior Rassi A
- Lana M
- Leeuwenburgh I
- Lima-Costa MF
- Livramento JA
- Lopes ER
- Lorosa ES
- Lugones HS
- Luquetti AO
- Luquetti AO
- Luquetti AO
- Luquetti AO
- Lúcia Maria da Cunha Galvão
- Macêdo VO
- Macêdo VO
- Mady C
- Maegawa FA
- Maguire JH
- Mahoney RT
- Mallimaci MC
- Maria Aparecida Shikanai-Yasuda
- Marin-Neto JA
- Marin-Neto JA
- Marin-Neto JA
- Marin-Neto JA
- Marin-Neto JA
- Martes ACB
- Martinelli Filho M
- Martins-Melo FR
- Martins-Melo FR
- Martins-Melo FR
- Martins-Melo FR
- Martins-Melo FR
- Martins-Melo FR
- Martins-Melo FR
- Mayara Maia Lima
- Medeiros MB
- Meier-Ruge WA
- Mendes EV
- Messenger LA
- Molina I
- Moncayo A
- Montera MW
- Moraes-Souza H
- Morais BB
- Morillo CA
- Mougabure-Cueto G
- Nishioka SA
- Nisida IV
- Norman FF
- Noya BA
- Noêmia Barbosa Carvalho
- Nóbrega AA
- Nóbrega AA
- Oliveira Júnior W
- Oliveira Júnior W
- Oliveira RB
- Ostermayer AL
- Ozaki Y
- Padilla-Torres SD
- Parada H
- Pasricha PJ
- Passos ADC
- Pazin-Filho A
- Pereira Barretto AC
- Perez-Ramirez L
- Pessoa GCA
- Pessoa GCA
- Pinazo MJ
- Pinotti HW
- Pinto AY
- Pinto AY
- Pinto AYN
- Pinto AYN
- Pinto AYN
- Portela-Lindoso AAB
- Porto CC
- Prata A
- Prata A
- Prata A
- Prata A
- Pérez-Ayala A
- Pérez-Molina JA
- Rafaella Albuquerque e Silva
- Ramos G
- Ramos Júnior AN
- Ramos Júnior AN
- Ramos Júnior AN
- Rassi A
- Rassi A
- Rassi Jr A
- Rassi Júnior A
- Rassi Júnior A
- Rassi Júnior A
- Rassi Júnior A
- Rassi Júnior A
- Reis-Neto JA
- Renato Vieira Alves
- Requena-Méndez A
- Rezende JM
- Riarte A
- Ribeiro dos Santos R
- Roberti RR
- Rocha A
- Rocha MOC
- Rodriguez-Salas LA
- Romaña C
- Roque AL
- Roque AL
- Rosália Morais Torres
- Roux E
- Roux E
- Russomando G
- Salas NA
- Salvatella R
- Samuel J
- Sangenis LH
- Santo AH
- Santos CB
- Sartori AM
- Scanavacca M
- Scapellato PG
- Schijman AG
- Schmunis GA
- Sebastião Aldo da Silva Valente
- Sergio Salles Xavier
- Shaw J
- Shikanai-Yasuda MA
- Shikanai-Yasuda MA
- Shikanai-Yasuda MA
- Silva CP
- Silvana Eloi Santos
- Silveira AC
- Silveira AC
- Silveira AC
- Silveira C
- Silveira JF
- Simone Monzani Vivaldini
- Simões MV
- Sosa Estani S
- Sosa-Estani S
- Sousa AA
- Sousa AS
- Souza DSM
- Spiess AE
- Spina-França A
- Stavropoulos SN
- Strasen J
- Suelene Mamede Oliveira
- Swanstrom LL
- Sánchez-Camargo CL
- Torrico F
- Valença-Barbosa C
- Ventura-Garcia L
- Vera da Costa Valente
- Veruska Maia da Costa
- Victora CG
- Victora CG
- Villela E
- Vinhaes MC
- Viotti R
- Viotti R
- Viotti RJ
- Voller A
- Wendell S
- Wilson de Oliveira Jr.
- Xavier SC
- Xavier SC
- Xavier SS
- Xavier SS
- Yun O
- Zicker F
- Zimerman LI
- Zingales B
- Zingales B
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2016
- Field of study
Abstract Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts. The disease represents a significant public health issue in Brazil, with different regional patterns. This document presents the evidence that resulted in the Brazilian Consensus on Chagas Disease. The objective was to review and standardize strategies for diagnosis, treatment, prevention, and control of Chagas disease in the country, based on the available scientific evidence. The consensus is based on the articulation and strategic contribution of renowned Brazilian experts with knowledge and experience on various aspects of the disease. It is the result of a close collaboration between the Brazilian Society of Tropical Medicine and the Ministry of Health. It is hoped that this document will strengthen the development of integrated actions against Chagas disease in the country, focusing on epidemiology, management, comprehensive care (including families and communities), communication, information, education, and research
Lingual Cortical Mandibular Bone Depression: Frequency and Clinical-Radiological Features in a Brazilian Population
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Computer aided identification of a Hevein-like antimicrobial peptide of bell pepper leaves for biotechnological use
- Author
- A Bairoch
- A Perez-de-Luqye
- A Shevchenko
- AA Astafieva
- AA Slavokhotova
- AJ Otero-González
- Alessandra Faria-Campos
- B Ma
- B Thiede
- B Zeitler
- BL Archer
- C Qin
- C Remuzgo
- CD Fjell
- CMA Morgado
- D Benson
- DN Perkins
- E Boutet
- E Gasteiger
- E Holásková
- E Montesinos
- E Souza-Cândido de
- EA Rogozhin
- Elói Quintas Gonçalves daSilva
- F García-Olmedo
- F Golshani
- F Lipnizki
- F Sievers
- FR Teixeira
- G Maróti
- G Wang
- Gloria Regina Franco
- H McWilliam
- H Schägger
- Hebréia Oliveira Almeida-Souza
- IB Holme
- IM Gould
- J Sels
- J Yan
- K Guruprasad
- K Kanokwiroon
- KD Pruitt
- L Zhang
- LL Utkina
- LS Tavares
- M Farooq
- M Khaliluev
- Marcos Jorge deMagalhães-Jr
- Maria Cristina Baracat-Pereira
- Maura Vianna Prates
- Meire de Oliveira Barbosa
- N Marmiroli
- NG Tessarollo
- NS Parachin
- P Minkiewicz
- P Schulz-Knappe
- P Tavormina
- Patrícia Dias Games
- Patrícia Pereira Fontes
- Paulo Roberto Gomes Pereira
- PD Games
- PK Smith
- PV Dubovskii
- R Hammami
- R Nawrot
- RDO Dias
- RR Shukurov
- SF Altschul
- SF Altschul
- SF Altschul
- SF Altschul
- Sérgio Vale Aguiar Campos
- TA Egorov
- TI Odintsova
- TI Odintsova
- V Neuhoff
- WF Porto
- WH Wu
- X Zhao
- Y Wu
- YA Andreev
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Efficacy of graded activity versus supervised exercises in patients with chronic non-specific low back pain: protocol of a randomised controlled trial
- Author
- A Bjerkefors
- A Delitto
- AA Florindo
- Amélia Pasqual Marques
- Ana Paula de Moura Campos Carvalho e Silva
- BF Walker
- BW Koes
- C Costa Lda
- C Menezes Costa Lda
- C Smith
- DG Altman
- FB Siqueira
- FK Varoli
- FR Franca
- FR Franca
- FS de Souza
- Fábio Jorge Renovato França
- Gabriel Peixoto Leao Almeida
- I Lindstrom
- JM Ocarino
- KF Schulz
- KP Barr
- L Nusbaum
- LA Danneels
- LG Macedo
- LG Macedo
- LG Macedo
- LO Costa
- LO Costa
- Luiz Armando Vidal Ramos
- M Roland
- Mauricio Oliveira Magalhaes
- McARDLE ea
- MT Navega
- N Dufour
- O Airaksinen
- P Hodges
- PW Hodges
- PW Hodges
- RJ Shephard
- RJ Smeets
- RJ Smeets
- RM Ciconelli
- RN van der Giessen
- S Dagenais
- SD Rundell
- SE Lamb
- SE Lamb
- Susan Lee King Yuan
- Thomaz Nogueira Burke
- Y Javadian
- Y Okubo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Determinantes do envelhecimento ativo segundo a qualidade de vida e gênero
- Author
- Alexandre TS
- Almeida OP
- Ana Cristina Viana Campos
- Andréa Maria Duarte Vargas
- Bowling A
- Bowling A
- Brucki SMD
- Camarano AM
- Cherepanov D
- De Luca d’Alessandro E
- Dollard J
- Duarte YAO
- Efigenia Ferreira e Ferreira
- Farias RG
- Fernandes MGM
- Ferreira OGL
- Figueira HA
- Figueiredo MLF
- Fleck MPA
- Fleck MPA
- Geib LLTC
- Gontijo EEL
- Hair JF
- Hekmatpou D
- Hosmer DW
- Kirchengast S
- Kishimoto Y
- Lebrão ML
- Lowsky DJ
- Martins JJ
- Mendoza-Núñez VM
- Moraes JF
- Nicolussi AC
- Oliveira SES
- Pregibon D
- Quiroga P
- Ribeiro PCC
- Santos JLF
- Silva HS
- Thanakwang K
- Trentini CM
- Vicente FR
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Prevalência de excesso de peso e obesidade abdominal, segundo parâmetros antropométricos, e associação com maturação sexual em adolescentes escolares
- Author
- Adair LS
- Alcides da Silva Diniz
- Almeida CAN
- Ana Márcia Tenório de Souza Cavalcanti
- Barbosa KBF
- Bini V
- Campos LA
- Castilho SD
- Chinn S
- Cole TJ
- Conde WL
- Farias Júnior JC
- Flegal KM
- Garnett SP
- Garnett SP
- Giugliano R
- Henderson RH
- Ilma Kruze Grande de Arruda
- Isabel Carolina da Silva Pinto
- James PT
- Janssen I
- Kahn HS
- Li C
- Lohman TG
- McCarthy HD
- Must A
- Must A
- Must A
- Oliveira CS
- Saito MI
- Sant'Anna MSL
- Savva SC
- Silva GAP
- Soar C
- Suñé FR
- Tanner JM
- Taylor RW
- Terres NG
- Tomkins A
- Veiga GV
- Wang Y
- Wang Y
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
- Ahmad A
- Ahmad N
- Ahmad T
- Ahmad T
- Ahmad Y
- Ahmed A
- Ahmed J
- Ai Y
- Aignatoaie M
- Aimoniotou-Georgiou E
- Akanmu O
- Akerman N
- Akinwale M
- Akring I
- Al 'Amri K
- Al Anizi M
- Al hussaini S
- Al-Soudaine Y
- Aladin H
- Alagbe-Briggs O
- Alaman Laguarda G
- Albaj S
- Alcock D
- Alcock L
- Aldecoa C
- Aldecoa C
- Aleixo FB
- Alexander H
- Alexander M
- Alexander-Sefre F
- Alherz F
- Ali H
- Ali M
- Ali S
- Alias A
- Alias AH
- Alias RLR
- Alit MA
- Allen S
- Allen SJ
- Allison J
- Alloj C
- Allorto NL
- Allsop J
- Almeida W
- Alonso E
- Alphonsus C
- Alvares D
- Alves MJ
- Amador JCB
- Ameer Y
- Amendola CP
- Ami N
- Amstrup-Hansen L
- Anagnou A
- Andersen C
- Anderson C
- Anderson C
- Anderson F
- Anderson P
- Andreadaki E
- Andreou A
- Andreou P
- Andrew A
- Andrews E
- Angermair S
- Angus K
- Anillo V
- Antal O
- Antill P
- Antoniadou E
- Antonina W
- Apagaki E
- Apostolou K
- Applewhaite C
- Aquino LPG
- Ar P
- Arawwawala D
- Ardern D
- Argue R
- Arkalaki E
- Armaganidis A
- Armstrong J
- Armstrong R
- Arnaoutoglou C
- Arnaoutoglou E
- Arnold G
- Arrandale L
- Arrich J
- Arrigo M
- Arshad H
- Arshad MA
- Arumugam S
- Arustei M
- Arvaniti K
- Arya A
- Arya S
- Asimakos A
- Asudo F
- Athanasakis E
- Atiku M
- Attrill E
- Attwood C
- Auer P
- Avidan M
- Avila Sanchez FJ
- Avila EJD
- Avis J
- Awad H
- Axioti E
- Ayyaz H
- Azam UAA
- Azambuja P
- Azevedo C
- Aziz FZ
- Baas P
- Baghirzada L
- Bai H-P
- Bai Y
- Baillie S
- Baines D
- Baio TH
- Bairaktari A
- Baker G
- Baker K-A
- Baker P
- Balain B
- Balaji P
- Balajonda N
- Balanescu A
- Balasubramaniam M
- Baldisserotto S
- Baldwin J
- Baldwin M
- Balfoussia D
- Bali C
- Bandeira ME
- Banerjee R
- Bankewitz C
- Banner-Goodspeed V
- Bao Q
- Barcraft-Barnes H
- Barneto L
- Barnett A
- Baroselli A
- Barraclough J
- Barras J-P
- Barrett S
- Barrett WJ
- Basanth S
- Batchelor N
- Bateman B
- Bates A
- Bates S
- Batista HD
- Bauchmuller K
- Bauer M
- Baumgarten G
- Baxter L
- Beaton C
- Beattie S
- Beavis V
- Bechan S
- Bejia T
- Belciu I
- Belda MT
- Bell G
- Bell R
- Bell S
- Bellandi M
- Bello J
- Beloeil H
- Belskiy V
- Ben-Menachem E
- Benavent P
- Benevento A
- Bengeri S
- Bennett C
- Bennett M
- Bennett R
- Bennett V
- Bentley C
- Beretta L
- Berg A
- Bergin C
- Bernard A
- Berntsen E
- Bertram W
- Bester D
- Bester M
- Bettega F
- Bettinelli A
- Bhardwaj N
- Bhatia K
- Bhula C
- Bi Y
- Biais M
- Biccard BM
- Bidd H
- Bidgoli J
- Biffen A
- Bignami E
- Bilolikar A
- Bin Mustapha MT
- Birch J
- Bishop DG
- Biyase T
- Bizios C
- Blackwell C
- Blackwood D
- Blaj M
- Blakemore SP
- Bland M
- Blunt M
- Blyth K
- Bocchino S
- Bodansky D
- Bodger P
- Boer C
- Boereboom C
- Boggiano V
- Bogner G
- Bolaji B
- Bolton D
- Boone M
- Boschi L
- Boshier P
- Botes M
- Botis I
- Bottini C
- Bottrill F
- Bouchez S
- Boulton K
- Bouris V
- Bourner L
- Boutsikos G
- Bouwman A
- Bouwman RA
- Bowrey S
- Boxall L
- Boyd C
- Bradburn M
- Bradley J
- Branagan G
- Branco T
- Brand B
- Brandsborg B
- Breitenstein S
- Brennan A
- Brennan E
- Brenner L
- Brincat M
- Briscoe R
- Bristogiannis S
- Brooke J
- Brookes J
- Brookes M
- Brooks C
- Broomby R
- Brotto AF
- Brown A
- Brown CW
- Brown G
- Brown J
- Brown J
- Brown L
- Brown R
- Brown R
- Browning J
- Bruma D
- Brunete T
- Brunswicker A
- Bryant H
- Bua E
- Buccimazza I
- Buckley S
- Buerkle C
- Buhre W
- Buhre W
- Buhrer T
- Builu PM
- Buise M
- Bullock C
- Bunwarie B
- Burns K
- Burrows L
- Burrows T
- Burston B
- Burtenshaw A
- Burton M
- Busuioc M
- Butryn I
- Butt G
- Byrne K
- Cabezuelo E
- Cabral R
- Cabral TDN
- Cabrini L
- Cacala S
- Cai F
- Cai Y
- Cain H
- Cairns C
- Cakova V
- Calderwood C
- Callaghan M
- Campbell D
- Campbell D
- Campbell D
- Campbell G
- Campbell G
- Campbell K
- Campbell M
- Campbell T
- Campey L
- Camsooksai J
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- Zoulamoglou M
- Zsisku L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
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