640 research outputs found

    Inductance Calculation and Torque Separation of a Unique Multi-Layer Spoke-type Interior Permanent Magnet Motor using the Frozen Permeability Method

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    Frozen permeability approach (FP) is employed to separate the average torque components (reluctance and permanent magnet torque) and for the inductance calculation for a Unique Ferrite Multi-Layer Spoke-type Interior Permanent Magnet Motor. Finite element analyses (FEA) models are built to provide many results help to offer more insight analysis. Three factors are taking in account to analyse their effects: permanent magnetism, armature currents of stator and angular rotor position. Also, different saturation levels are analysed, to reveal the influence of magnetic saturation and crosscoupling. These detailed analyses are providing valuable insights for permanent machine design and optimization

    Rancang Bangun dan Penerapan Mesin Ayakan Gula Semut di Kabupaten Kulonprogo, Daerah Istimewa Yogyakarta

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    Gula Semut is a sugar made from palm nectar or also called Neera that has gone through several processes before it is ready in a form that convenience for us to consume. This study aims to design and fabricate the vibrating sieve machine to separate gula semut (cristalized sugar) based on particle size. The machine has a capacity of 50 kg/h depending on the raw material. The machine consists of several main parts such as siever, electric motor, vibrating spring, balancer and frame. Simple calculation has been conducted to meet the capacity of the machine. The machine was made of food grade stainless steel to prevent contamination in gula semut due to corrosion. A preliminary experiment has been carried out to evaluate the performance of the machine including adjusting the balancer position. Finally, the machine will increase the productivity of gula semut industry in Kulonprogo District

    EXTRA: Towards the exploitation of eXascale technology for reconfigurable architectures

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    © 2016 IEEE. To handle the stringent performance requirements of future exascale-class applications, High Performance Computing (HPC) systems need ultra-efficient heterogeneous compute nodes. To reduce power and increase performance, such compute nodes will require hardware accelerators with a high degree of specialization. Ideally, dynamic reconfiguration will be an intrinsic feature, so that specific HPC application features can be optimally accelerated, even if they regularly change over time. In the EXTRA project, we create a new and flexible exploration platform for developing reconfigurable architectures, design tools and HPC applications with run-time reconfiguration built-in as a core fundamental feature instead of an add-on. EXTRA covers the entire stack from architecture up to the application, focusing on the fundamental building blocks for run-time reconfigurable exascale HPC systems: new chip architectures with very low reconfiguration overhead, new tools that truly take reconfiguration as a central design concept, and applications that are tuned to maximally benefit from the proposed run-time reconfiguration techniques. Ultimately, this open platform will improve Europe's competitive advantage and leadership in the field

    A new methodology for characterizing traction-separation relations for interfacial delamination of thermal barrier coatings

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    The ability to characterize the interfacial delamination properties of thermal barrier coatings (TBCs) is of great technological importance for lifetime assessment of such coatings under service conditions. The purpose of this paper is to report on our novel experimental-plus-simulation-based approach to determine the relevant material parameters appearing in a traction-separation-type law which should be useful for modeling delamination failures in TBCs. We combine load–displacement measurements obtained from (i) a standard tension experiment; (ii) a novel shear experiment; and (iii) a novel asymmetric four-point bending mixed-mode experiment, with simulations of these experiments using a representative traction-separation law in a finite-element program, to extract the requisite material parameters for this traction-separation model. The methodology is applied to determine the material parameters for a TBC system (consisting of an air-plasma-sprayed yttria-stabilized-zirconia top-coat and an MCrAlY bond-coat sprayed on a superalloy substrate) which has been isothermally exposed to air at 1100 °°C for 144 h prior to testing.National Science Foundation (U.S.) (NSF (CMMI Award No. 1063626))King Fahd University of Petroleum and Minerals (Project Number R9-CE-08)Center for Clean Water and Clean Energy at MIT and KFUPM (Project Number R9-CE-08

    EXTRA: Towards an efficient open platform for reconfigurable High Performance Computing

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    To handle the stringent performance requirements of future exascale-class applications, High Performance Computing (HPC) systems need ultra-efficient heterogeneous compute nodes. To reduce power and increase performance, such compute nodes will require hardware accelerators with a high degree of specialization. Ideally, dynamic reconfiguration will be an intrinsic feature, so that specific HPC application features can be optimally accelerated, even if they regularly change over time. In the EXTRA project, we create a new and flexible exploration platform for developing reconfigurable architectures, design tools and HPC applications with run-time reconfiguration built-in as a core fundamental feature instead of an add-on. EXTRA covers the entire stack from architecture up to the application, focusing on the fundamental building blocks for run-time reconfigurable exascale HPC systems: new chip architectures with very low reconfiguration overhead, new tools that truly take reconfiguration as a central design concept, and applications that are tuned to maximally benefit from the proposed run-time reconfiguration techniques. Ultimately, this open platform will improve Europe's competitive advantage and leadership in the field

    Research Priorities for Endometriosis:Recommendations From a Global Consortium of Investigators in Endometriosis

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    The 3rd International Consensus Workshop on Research Priorities in Endometriosis was held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis. The workshop was attended by 60 participants from 19 countries and was divided into 5 main sessions covering pathogenesis/pathophysiology, symptoms, diagnosis/classification/prognosis, disease/symptom management, and research policy. This research priorities consensus statement builds on earlier efforts to develop research directions for endometriosis. Of the 56 research recommendations from the 2011 meeting in Montpellier, a total of 41 remained unchanged, 13 were updated, and 2 were deemed to be completed. Fifty-three new research recommendations were made at the 2014 meeting in Sao Paulo, which in addition to the 13 updated recommendations resulted in a total of 66 new recommendations for research. The research recommendations published herein, as well as those from the 2 previous papers from international consensus workshops, are an attempt to promote high-quality research in endometriosis by identifying and agreeing on key issues that require investigation. New areas included in the 2014 recommendations include infertility, patient stratification, and research in emerging nations, in addition to an increased focus on translational research. A revised and updated set of research priorities that builds on this document will be developed at the 13th World Congress on Endometriosis to be held on May 17-20, 2017, in Vancouver, British Columbia, Canada.Peter A. W. Rogers, G. David Adamson, Moamar Al-Jefout, Christian M. Becker, Thomas M. D, Hooghe, Gerard A. J. Dunselman, Asgerally Fazleabas, Linda C. Giudice, Andrew W. Horne, M. Louise Hull, Lone Hummelshoj, Stacey A. Missmer, Grant W. Montgomery, Pamela Stratton, Robert N. Taylor, Luk Rombauts, Philippa T. Saunders, Katy Vincent, Krina T. Zondervan for the WES/WERF Consortium for Research Priorities in Endometriosi

    Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo

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    Several people with Parkinson’s disease have been treated with intrastriatal grafts of fetal dopaminergic neurons. Following autopsy, 10–22 years after surgery, some of the grafted neurons contained Lewy bodies similar to those observed in the host brain. Numerous studies have attempted to explain these findings in cell and animal models. In cell culture, α-synuclein has been found to transfer from one cell to another, via mechanisms that include exosomal transport and endocytosis, and in certain cases seed aggregation in the recipient cell. In animal models, transfer of α-synuclein from host brain cells to grafted neurons has been shown, but the reported frequency of the event has been relatively low and little is known about the underlying mechanisms as well as the fate of the transferred α-synuclein. We now demonstrate frequent transfer of α-synuclein from a rat brain engineered to overexpress human α-synuclein to grafted dopaminergic neurons. Further, we show that this model can be used to explore mechanisms underlying cell-to-cell transfer of α-synuclein. Thus, we present evidence both for the involvement of endocytosis in α-synuclein uptake in vivo, and for seeding of aggregation of endogenous α-synuclein in the recipient neuron by the transferred α-synuclein. Finally, we show that, at least in a subset of the studied cells, the transmitted α-synuclein is sensitive to proteinase K. Our new model system could be used to test compounds that inhibit cell-to-cell transfer of α-synuclein and therefore might retard progression of Parkinson neuropathology
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