SENTIMENT OF INDOVAC VACCINE LAUNCH NEWS ON DETIK.COM USING DISCOURSE NETWORK ANALYSIS

This study aims to determine the sentiment of the news of the domestically produced IndoVac Vaccine launch. The pros and cons sentiments of Detik.com's coverage were analyzed using Discourse Network Analysis (DNA) and network visualization using Visone software. The study results are based on news related to the IndoVac vaccine from September 3 to November 30, 2022; there are 50 news stories with 193 statements from 33 Actors. Information, Policy, and Education categories were found, with 93% positive and 7% negative statements. The influence of the IndoVac Vaccine makes social media users more careful in digging up information to understand media coverage, especially regarding the IndoVac vaccine

JEAN PIAGET THEORY PERSPERCTIVE ON INTERPERSONAL COMMUNICATION BETWEEN PARENTS AND CHILDREN IN THE STAGE OF GADGET ADDICTION

The purpose of this study is to analyze how interpersonal communication occurs between parents and children in the stage of gadget addiction using the perspective of Jean Piaget's theory. Researchers used the phenomenological paradigm to explore informants' experiences about the interpersonal communication process that occurred. In-depth interviews were conducted with informants to explore communication patterns between parents and their children. The results showed that the forms of communication carried out by parents to children in gadget addiction were divided into 3 groups, namely in a liberating, democratic, and authoritarian manner. The most intense communication process occurs in groups that use democracy. Using Piaget's perspective, the process of children's addiction begins at the Preoperational stage, where children begin to represent the world with symbols, words, language, and images

Hemodynamic and Echocardiographic Assessment of Left Ventricle Recovery with Left Ventricular Assist Devices: Do We Explant?

Introduction: Explantation of left ventricular assist devices (LVAD) after left ventricular (LV) recovery is estimated to occur in 1-2% of cases. Herein, we present a case of hemodynamic and echocardiographic assessment of LV recovery during outflow graft balloon occlusion leading to LVAD explantation. Case Report: A 56-year-old female with medical history of systolic heart failure due to non-ischemic cardiomyopathy with LVEF 25%. She underwent an urgent HeartMate 3 LVAD implant after an admission for cardiogenic shock. Post LVAD course was complicated by driveline infection. History was notable for admissions due to low-flow alarms in the setting of dehydration. On echocardiogram, progressive LVEF improvement was noted although with suboptimal images. CT angiography did not demonstrate any occlusion of the cannulas. Right heart catheterization showed stable cardiac index despite minimal flow on LVAD. Cardiopulmonary testing was favorable. After multi-disciplinary discussion, patient underwent LVAD wean study in the cath lab under hemodynamic and transesophageal echo (TEE) guidance with therapeutic anticoagulation. LVAD was turned off for 10 minutes with outflow graft occluded by Armada 14 mm x 20 cm peripheral balloon. Wiring of the outflow graft from aorta and balloon occlusion were visualized by TEE (Figure). The left and right ventricular function were similar to baseline with no change in mitral regurgitation. Cardiac index was normal (Figure). Patient subsequently underwent successful LVAD explant. She is doing well with NYHA class I symptoms and LVEF 45-50% noted upon 3-months follow-up LVAD explantation is a feasible option in LV recovery after appropriate hemodynamic and echocardiographic assessment. TEE is an essential tool, especially in patients with suboptimal windows. Outflow graft balloon occlusion can be used if there is concern about falsely poor results related to backflow or ongoing LVAD support at low speed leading to falsely improved results

The randomized clinical trial trustworthiness crisis

Background The rising number of retracted randomised clinical trials (RCTs) is a concern over their trustworthiness. In today’s digital landscape electronic observational data is easily accessible for research purposes. This emerging perspective, in tandem with the growing scrutiny of RCT credibility, may steer some researchers towards favouring non-randomized studies. It is crucial to emphasize the ongoing need for robust RCTs, shedding light on the areas within trial design that require enhancements and addressing existing gaps in trial execution. Main body Evidence-based medicine pivots on the nexus between empirical medical research and the theoretical and applied facets of clinical care. Healthcare systems regularly amass patient data, creating a vast reservoir of information. This facilitates large-scale observational studies, which may appear as potential substitutes for RCTs. These large-scale studies inherently possess biases that place them a notch below randomized evidence. Honest errors, data manipulation, lapses in professionalism, and methodological shortcomings tarnish the integrity of RCTs, compromising trust in trials. Research institutions, funding agencies, journal editors and other stakeholders have the responsibility to establish robust frameworks to prevent both deliberate and inadvertent mishandling of RCT design, conduct and analysis. Systematic reviews that collate robust RCTs are invaluable. They amalgamate superior evidence instrumental in improving patient outcomes via informed health policy decisions. For systematic reviews to continue to retain trust, validated integrity assessment tools must be developed and routinely applied. This way it will be possible to prevent false or untrustworthy research from becoming part of the recommendations based on the evidence. Conclusion High-quality RCTs and their systematic reviews play a crucial role in acquiring valid and reliable evidence that is instrumental in improving patient outcomes. They provide vital information on healthcare effectiveness, and their trustworthiness is key to evidence-based medicine.Beatriz Galindo (senior modality) programme of the Spanish Ministry of Educatio

A preliminary report on the distribution of lizards in Qatar

We have updated the list of the lizard species present in Qatar and produced the first distribution maps based on two field surveys in 2012 and 2013. We used the QND95/Qatar National Grid with a grid of 10 × 10 km squares for mapping. Our results show the occurrence of 21 lizard species in Qatar, from the 15 species indicated in the last biodiversity report conducted in 2004. The most abundant family found in Qatar is Gekkonidae with nine species (Bunopus tuberculatus, Cyrtopodion scabrum, Hemidactylus robustus, H. flaviviridis, H. persicus, Stenodactylus arabicus, S. slevini, S. doriae, Pseudoceramodactylus khobarensis), followed by Lacertidae with four species (Acanthodactylus schmidti, A. opheodurus, Mesalina brevirostris, M. adramitana), Agamidae with three species (Trapelus flavimaculatus, Uromastyx aegyptia, Phrynocephalus arabicus), Scincidae with two species (Scincus mitranus, Trachylepis septemtaeniata), and Varanidae (Varanus griseus), Sphaerodactylidae (Pristurus rupestris) and Trogonophiidae (Diplometopon zarudnyi) with one species each. The species richness fluctuated largely across Qatar between one and eleven species per grid square. We believe that the lizard fauna records in Qatar are still incomplete and that additional studies are required. However, our study here fills a gap concerning lizard biodiversity knowledge in the Gulf Region. © Dan Cogǎlniceanu et al.Peer Reviewe

Pemberdayaan Anak-anak Desa Sudimoro dengan Pembelajaran Kosakata & Numerasi Melalui DUDADAU. EDU Fun Game dan Education

Perkembangan ilmu pengetahuan dan teknologi telah membawa perubahan yang signifikan terhadap berbagai dimensi kehidupan manusia, Pendidikan merupakan ujung tombak dalam pembangunan masa depan suatu bangsa. Oleh karena itu prubahan dan perbaikan terus dilakukan pada berbagai sektor Pendidikan, dalam hal ini peneliti ingin membuat inovasi dalam Pendidikan yaitu membuat sebuah media pembelajaran yang bernama “ DUDADADU.EDU “pembelajaran Kosa Kata dan Numerisasi berbasis Fun Game dan Education. Metode yang digunakan adalah metode pendekatan untuk pelaksanaan kegiatan ini menggunakan model pembelajaran koperatif tipe STAD merupakan model yang menekankan pada aktivitas dan interaksi anatar siswa untuk saling membantu dalam penguasaan materi, tujuan dari pengabdian ini adalah untuk meningkatkan minat dan semangat para siswa di desa sudimoro, hasil yang di capai dalam kegiatan ini antara lain dampak bagi pembelajaran siswa, dan juga bagi social