1,351 research outputs found
Fitting Parton Distribution Data with Multiplicative Normalization Uncertainties
We consider the generic problem of performing a global fit to many
independent data sets each with a different overall multiplicative
normalization uncertainty. We show that the methods in common use to treat
multiplicative uncertainties lead to systematic biases. We develop a method
which is unbiased, based on a self--consistent iterative procedure. We
demonstrate the use of this method by applying it to the determination of
parton distribution functions with the NNPDF methodology, which uses a Monte
Carlo method for uncertainty estimation.Comment: 33 pages, 5 figures: published versio
Meaningful characterisation of perturbative theoretical uncertainties
We consider the problem of assigning a meaningful degree of belief to
uncertainty estimates of perturbative series. We analyse the assumptions which
are implicit in the conventional estimates made using renormalisation scale
variations. We then formulate a Bayesian model that, given equivalent initial
hypotheses, allows one to characterise a perturbative theoretical uncertainty
in a rigorous way in terms of a credibility interval for the remainder of the
series. We compare its outcome to the conventional uncertainty estimates in the
simple case of the calculation of QCD corrections to the e+e- -> hadrons
process. We find comparable results, but with important conceptual differences.
This work represents a first step in the direction of a more comprehensive and
rigorous handling of theoretical uncertainties in perturbative calculations
used in high energy phenomenology.Comment: 28 pages, 5 figures. Language modified in order to make it more
'bayesian'. No change in results. Version published in JHE
Theoretical Uncertainties in Electroweak Boson Production Cross Sections at 7, 10, and 14 TeV at the LHC
We present an updated study of the systematic errors in the measurements of
the electroweak boson cross-sections at the LHC for various experimental cuts
for a center of mass energy of 7, 10 and 14 TeV. The size of both electroweak
and NNLO QCD contributions are estimated, together with the systematic error
from the parton distributions. The effects of new versions of the MSTW, CTEQ,
and NNPDF PDFs are considered.Comment: PDFLatex with JHEP3.cls. 22 pages, 43 figures. Version 2 adds the
CT10W PDF set to analysis and updates the final systematic error table and
conclusions, plus several citations and minor wording changes. Version 3 adds
some references on electroweak and mixed QED/QCD corrections. Version 4 adds
more references and acknowledgement
Bragg Grating Corrosion Sensor
Historically, corrosion has not been included in the calculation of the life expectancy of aircraft. It is well known how stress-corrosion cracking and corrosion fatigue can significantly reduce the life expectancy of structures. Therefore, it can be correctly assumed that some aircraft flying near their expected life might actually be flying well beyond their âsafe lifeâ. Furthermore, due to DoD present tight budget requirements, its is expected that some defense aircraft might not be retired at their original expected life but will be reconditioned to fly beyond that time. All of these considerations indicate that early detection, quantification and prevention of corrosion is of critical importance for military aircraft. This is particularly true for Navy aircraft which fly in the most corrosive environment of all services
Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants
Background
The consequences of preterm birth are a major public health concern with high rates of ensuing multisystem morbidity, and uncertain biological mechanisms. Common genetic variation may mediate vulnerability to the insult of prematurity and provide opportunities to predict and modify risk.
Objective
To gain novel biological and therapeutic insights from the integrated analysis of magnetic resonance imaging and genetic data, informed by prior knowledge.
Methods
We apply our previously validated pathway-based statistical method and a novel network-based method to discover sources of common genetic variation associated with imaging features indicative of structural brain damage.
Results
Lipid pathways were highly ranked by Pathways Sparse Reduced Rank Regression in a model examining the effect of prematurity, and PPAR (peroxisome proliferator-activated receptor) signaling was the highest ranked pathway once degree of prematurity was accounted for. Within the PPAR pathway, five genes were found by Graph Guided Group Lasso to be highly associated with the phenotype: aquaporin 7 (AQP7), malic enzyme 1, NADP(+)-dependent, cytosolic (ME1), perilipin 1 (PLIN1), solute carrier family 27 (fatty acid transporter), member 1 (SLC27A1), and acetyl-CoA acyltransferase 1 (ACAA1). Expression of four of these (ACAA1, AQP7, ME1, and SLC27A1) is controlled by a common transcription factor, early growth response 4 (EGR-4).
Conclusions
This suggests an important role for lipid pathways in influencing development of white matter in preterm infants, and in particular a significant role for interindividual genetic variation in PPAR signaling
W boson production at hadron colliders: the lepton charge asymmetry in NNLO QCD
We consider the production of W bosons in hadron collisions, and the
subsequent leptonic decay W->lnu_l. We study the asymmetry between the rapidity
distributions of the charged leptons, and we present its computation up to the
next-to-next-to-leading order (NNLO) in QCD perturbation theory. Our
calculation includes the dependence on the lepton kinematical cuts that are
necessarily applied to select W-> lnu_l events in actual experimental analyses
at hadron colliders. We illustrate the main differences between the W and
lepton charge asymmetry, and we discuss their physical origin and the effect of
the QCD radiative corrections. We show detailed numerical results on the charge
asymmetry in ppbar collisions at the Tevatron, and we discuss the comparison
with some of the available data. Some illustrative results on the lepton charge
asymmetry in pp collisions at LHC energies are presented.Comment: 37 pages, 21 figure
On direct measurement of the W production charge asymmetry at the LHC
The prospects for making a direct measurement of the W production charge
asymmetry at the LHC are discussed. A modification to the method used at the
Tevatron is proposed for measurements at the LHC. The expected sensitivity for
such a measurement to parton distribution functions is compared to that for a
measurement of the lepton charge asymmetry. The direct measurement approach is
found to be less useful for placing constraints on parton distribution
functions at the LHC than a measurement of the lepton charge asymmetry.Comment: 18 pages, 10 figures, v2: references and keywords updated v3:
Additional paragraph discussing inclusion of W asymmetry in global fits adde
Extinction times in the subcritical stochastic SIS logistic epidemic
Many real epidemics of an infectious disease are not straightforwardly super-
or sub-critical, and the understanding of epidemic models that exhibit such
complexity has been identified as a priority for theoretical work. We provide
insights into the near-critical regime by considering the stochastic SIS
logistic epidemic, a well-known birth-and-death chain used to model the spread
of an epidemic within a population of a given size . We study the behaviour
of the process as the population size tends to infinity. Our results cover
the entire subcritical regime, including the "barely subcritical" regime, where
the recovery rate exceeds the infection rate by an amount that tends to 0 as but more slowly than . We derive precise asymptotics for
the distribution of the extinction time and the total number of cases
throughout the subcritical regime, give a detailed description of the course of
the epidemic, and compare to numerical results for a range of parameter values.
We hypothesise that features of the course of the epidemic will be seen in a
wide class of other epidemic models, and we use real data to provide some
tentative and preliminary support for this theory.Comment: Revised; 34 pages; 6 figure
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