8 research outputs found
Comments on thermodynamics of supersymmetric matrix models
We present arguments that the structure of the spectrum of the supersymmetric
matrix model with 16 real supercharges in the large N limit is rather
nontrivial, involving besides the natural energy scale ~\lambda^{1/3} = (g^2
N)^{1/3} also a lower scale ~\lambda^{1/3}N^{-5/9}. This allows one to
understand a nontrivial behaviour of the mean internal energy of the system, E
proportional to T^{14/5}, predicted by AdS duality arguments.Comment: 16 pages, LaTe
Polyakov Lines in Yang-Mills Matrix Models
We study the Polyakov line in Yang-Mills matrix models, which include the
IKKT model of IIB string theory. For the gauge group SU(2) we give the exact
formulae in the form of integral representations which are convenient for
finding the asymptotic behaviour. For the SU(N) bosonic models we prove upper
bounds which decay as a power law at large momentum p. We argue that these
capture the full asymptotic behaviour. We also indicate how to extend the
results to some correlation functions of Polyakov lines.Comment: 19 pages, v2 typos corrected, v3 ref adde
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Epstein-Barr virus: clinical and epidemiological revisits and genetic basis of oncogenesis
Epstein-Barr virus (EBV) is classified as a member in the order herpesvirales, family herpesviridae, subfamily gammaherpesvirinae and the genus lymphocytovirus. The virus is an exclusively human pathogen and thus also termed as human herpesvirus 4 (HHV4). It was the first oncogenic virus recognized and has been incriminated in the causation of tumors of both lymphatic and epithelial nature. It was reported in some previous studies that 95% of the population worldwide are serologically positive to the virus. Clinically, EBV primary infection is almost silent, persisting as a life-long asymptomatic latent infection in B cells although it may be responsible for a transient clinical syndrome called infectious mononucleosis. Following reactivation of the virus from latency due to immunocompromised status, EBV was found to be associated with several tumors. EBV linked to oncogenesis as detected in lymphoid tumors such as Burkitt's lymphoma (BL), Hodgkin's disease (HD), post-transplant lymphoproliferative disorders (PTLD) and T-cell lymphomas (e.g. Peripheral T-cell lymphomas; PTCL and Anaplastic large cell lymphomas; ALCL). It is also linked to epithelial tumors such as nasopharyngeal carcinoma (NPC), gastric carcinomas and oral hairy leukoplakia (OHL). In vitro, EBV many studies have demonstrated its ability to transform B cells into lymphoblastoid cell lines (LCLs). Despite these malignancies showing different clinical and epidemiological patterns when studied, genetic studies have suggested that these EBV- associated transformations were characterized generally by low level of virus gene expression with only the latent virus proteins (LVPs) upregulated in both tumors and LCLs. In this review, we summarize some clinical and epidemiological features of EBV- associated tumors. We also discuss how EBV latent genes may lead to oncogenesis in the different clinical malignancie
Defining the relationship of the optic radiation to the roof and floor of the ventricular atrium: A focused microanatomical study
OBJECTIVE The authors investigated the specific topographic relationship of the optic radiation fibers to the roof and floor of the ventricular atrium because the current literature is ambiguous. METHODS Thirty-five normal, adult, formalin-fixed cerebral hemispheres and 30 focused MRI slices at the level of the atrium were included in the study. The correlative anatomy of the optic radiation with regard to the atrial roof and floor was investigated in 15 specimens, each through focused fiber microdissections. The remaining 5 hemispheres were explored with particular emphasis on the trajectory of the collateral sulcus in relation to the floor of the atrium. In addition, the trajectory of the collateral sulcus was evaluated in 30 MRI scans. RESULTS The atrial roof was observed to be devoid of optic radiations in all studied hemispheres, whereas the atrial floor was seen to harbor optic fibers on its lateral part. Moreover, the trajectory of the intraparietal sulcus, when followed, was always seen to correspond to the roof of the atrium, thus avoiding the optic pathway, whereas that of the collateral sulcus was found to lead to either the lateral atrial floor or outside the ventricle in 88% of the cases, therefore hitting the visual pathway. CONCLUSIONS Operative corridors accessing the ventricular atrium should be carefully tailored through detailed preoperative planning and effective use of intraoperative navigation to increase patient safety and enhance the surgeon’s maneuverability. The authors strongly emphasize the significance of accurate anatomical knowledge. © AANS 2019