Optimal timing of post-operative haematocrit check in obstetric and gynaecological surgeries

Background: Haemorrhage is a feared albeit common complication of surgery in Obstetrics and Gynaecology. Measurement of haematocrit post operatively is believed to be part of good medical practice since it gives an inkling to intraoperative and immediate post-operative blood loss and the need for blood transfusion. The objective of the study is to determine if there was any difference between haematocrit values gotten on day 1 and 2 and also to determine the optimal time for the post-operative haematocrit check.Methods: One thousand patients who had surgery in the department of Obstetrics and Gynaecology of LAUTECH Teaching Hospital (LTH) and Bowen University Teaching Hospital (BUTH), Ogbomoso were recruited. Capillary blood samples were obtained at 24hours and 48 hours post operatively. The haematocrit was determined using a 24 place micro haematocrit centrifuge and the values checked using a haematocrit reader. Frequency tables and charts were made and results were tested for significance with level of significance (x) set at 0.05.Results: The mean age of the patients was 32.88±9.45, with a modal age group of 21-30years. The commonest obstetric surgery done was caesarean section (60.6%) while the commonest gynaecological surgery was myomectomy (13.8%). There is a significant difference between the haematocrit values gotten on day one and two (p= 0.000). There was significant difference between the haematocrit values on both days and the unit the patient was managed; the type of surgery done and the age group of the patient.Conclusion: The haematocrit on postoperative day 2 is more representative of the blood loss.Keywords: postoperative, haematocrit, obstetrics, gynaecolog

Barriers to Placenta Donation for Bio-Medical Reasearch Purposes Among Pregnant Women in a Tertiary Health Institution in Nigeria

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Towards oxidative denitrogenation of fuel oils: Vanadium oxide-catalysed oxidation of quinoline and adsorptive removal of quinoline-N-oxide using 2,6-pyridine-polybenzimidazole nanofibers

The study provides a technological method for the removal of nitrogen compounds from fuels, via oxidation and extractive adsorption. The use of batch process resulted in lack of specificity of the quinoline oxidation reaction with several products produced via ring-opening while the flow micro-reactor presented a high degree of selectivity to quinoline-N-oxide (67%). The application of molecularly imprinted 2,6-pyridine-polybenzimidazole nanofibers displayed excellent quinoline-N-oxide removal (86%) with an adsorption capacity (qe) of 4.8 mg/g. Isothermal titration calorimetry (ITC) interactions between quinoline-N-oxide and 2,6-PyPBI confirmed a favourable interaction. DFT studies on quinoline-N-oxide vs 2,6-PyPBI further indicated: (i) a hydrogen bonding (through amino group of 2,6-PyPBI and oxygen atoms of the quinoline-N-oxide), (ii) pi-pi stacking and (iii) van der Waals interactions. The selective oxidation and adsorption of nitrogen compounds present in fuel, which has been demonstrated here, would be a sustainable green chemistry technology for the production of clean fuel. Keywords: Vanadium(V) oxide, tert-Butylhydroperoxide (t-BuOOH), Quinoline, Oxidatio

Bottom-up approach synthesis of core-shell nanoscale zerovalent iron (CS-nZVI): Physicochemical and spectroscopic characterization with Cu(II) ions adsorption application

Single pot system in chemical reduction via bottom-up approach was used for the synthesis of core shell nanoscale zerovalent iron (CS-nZVI). CS-nZVI was characterized by a combination of physicochemical and spectroscopic techniques. Data obtained showed BET surface area 20.8643 m2/g, t-Plot micropore volume 0.001895 cm3/g, BJH volume pores 0.115083 cm3/g, average pore width 186.9268 Å, average pore diameter 240.753 Å, PZC 5.24, and pH 6.80. Surface plasmon Resonance from UV-Vis spectrophotometer was observed at 340 nm. Surface morphology from SEM and TEM revealed a spherical cluster and chain-like nanostructure of size range 15.425 nm −97.566 nm. Energy Dispersive XRF revealed an elemental abundance of 96.05% core shell indicating the dominance of nZVI. EDX showed an intense peak of nZVI at 6.2 keV. FTIR data revealed the surface functional groups of Fe–O with characteristics peaks at 686.68 cm−1, 569.02 cm−1 and 434 cm−1. In a batch technique, effective adsorption of endocrine disruptive Cu(II) ions was operational parameters dependent. Isotherm and kinetics studies were validated by statistical models. The study revealed unique characteristics of CS-nZVI and its efficacy in waste water treatment

An appraisal of pattern and presentation of gynaecological malignancies in Bowen University Teaching Hospital, Southwest Nigeria

Background: Gynaecological malignancies are cancers that occur in or on a woman's reproductive organs and genitals which includes the vulva, vagina, cervix, uterus, fallopian tubes, and ovaries. The prevalence of gynaecological malignancies varies from one country to another. The factors responsible for the observed variance includes lifestyle, dietary pattern, level of education and the sophistication of health care system. This study aims to identify the pattern and clinical presentations of gynaecological malignancies at Bowen University Teaching Hospital, Ogbomoso over a five-year period.Methods: This was a retrospective study involving one hundred and twenty-three (123) patients with a histological diagnosis of gynecological malignancy.Results: Patients with gynaecological malignancies accounted for 3.6% of the patients seen in the period under review. Majority of these patients were multiparous and between the age range of 50 and 69 years. The commonest form of gynaecological malignancy seen was cervical cancer.Conclusion: Health care programs and policies that strengthen public awareness campaigns, health education and health promotion like human papilloma virus vaccination and follow up surveillance will help to reduce the morbidity and mortality associated with gynaecological malignancies. Keywords: appraisal, pattern, presentation, gynaecological malignancie