171 research outputs found
Molecular phylogeny, morphology and their implications for the taxonomy of Eriocaulaceae
Fenologia de Syngonanthus mucugensis Giul. subsp. mucugensis e S. curralensis Moldenke (Eriocaulaceae), nos municípios de Mucugê e Morro do Chapéu, Chapada Diamantina, BA, Brasil
Growth and essential oil production by Martianthus leucocephalus grown under the edaphoclimatic conditions of Feira de Santana, Bahia, Brazil
Diversidade arbórea das florestas alto montanas no Sul da Chapada Diamantina, Bahia, Brasil
CSF β-amyloid predicts prognosis in patients with multiple sclerosis
Background: The importance of predicting disease progression in multiple sclerosis (MS) has increasingly been recognized, and hence reliable biomarkers are needed. Objectives: To investigate the prognostic role of cerebrospinal fluid (CSF) amyloid beta 1\u201342 (A\u3b2) levels by the determination of a cut-off value to classify patients in slow and fast progressors. To evaluate possible association with white matter (WM) and grey matter (GM) damage at early disease stages. Methods: Sixty patients were recruited and followed up for 3\u20135 years. Patients underwent clinical assessment, brain magnetic resonance imaging (MRI; at baseline and after 1 year), and CSF analysis to determine A\u3b2 levels. T1-weighted volumes were calculated. T2-weighted scans were used to quantify WM lesion loads. Results: Lower CSF A\u3b2 levels were observed in patients with a worse follow-up Expanded Disability Status Scale (EDSS; r = 120.65, p < 0.001). The multiple regression analysis confirmed CSF A\u3b2 concentration as a predictor of patients\u2019 EDSS increase (r = 120.59, p < 0.0001). Generating a receiver operating characteristic curve, a cut-off value of 813 pg/mL was determined as the threshold able to identify patients with worse prognosis (95% confidence interval (CI): 0.690\u20130.933, p = 0.0001). No differences in CSF tau and neurofilament light chain (NfL) levels were observed (p > 0.05). Conclusion: Low CSF A\u3b2 levels may represent a predictive biomarker of disease progression in MS
Flora fanerogâmica da Serra Negra, Minas Gerais, Brasil
O presente estudo teve como objetivo caracterizar a flora fanerogâmica da região da Serra Negra localizada no sul da Zona da Mata de Minas Gerais, entre os municípios de Lima Duarte, Rio Preto, Santa Bárbara do Monte Verde e Olaria. Embora considerada de importância biológica alta, esta região não possui nenhum registro anterior de dados florísticos, o que levou ao desenvolvimento deste levantamento, durante o período de 2003 a 2010. A vegetação é caracterizada por um mosaico de formações florestais e campestres onde se destacam os campos rupestres e florestas nebulares em altitudes que variam de 1300 a ca. 1700 m. Um total de 1033 espécies foi encontrado, distribuídas em 469 gêneros e 121 famílias sendo as mais representativas Orchidaceae (115 spp.), Asteraceae 54 spp.), Melastomataceae (56 spp.), Myrtaceae (53 spp.), Fabaceae, Poaceae e Rubiaceae (48 spp. cada), Bromeliaceae (43 spp.), Solanaceae (38 spp.) e Piperaceae (33 spp). Novos registros e endemismos para a flora mineira foram encontrados e 58 espécies estão citadas na lista de espécies ameaçadas de Minas Gerais
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