5,438 research outputs found
Report on problem of pressure distribution in oil body containing flowing water
CER57ATC41.February 11, 1957.For Petroleum Research Corporation, Denver, Colorado
Single-Shot Electron Diffraction using a Cold Atom Electron Source
Cold atom electron sources are a promising alternative to traditional
photocathode sources for use in ultrafast electron diffraction due to greatly
reduced electron temperature at creation, and the potential for a corresponding
increase in brightness. Here we demonstrate single-shot, nanosecond electron
diffraction from monocrystalline gold using cold electron bunches generated in
a cold atom electron source. The diffraction patterns have sufficient signal to
allow registration of multiple single-shot images, generating an averaged image
with significantly higher signal-to-noise ratio than obtained with unregistered
averaging. Reflection high-energy electron diffraction (RHEED) was also
demonstrated, showing that cold atom electron sources may be useful in
resolving nanosecond dynamics of nanometre scale near-surface structures.Comment: This is an author-created, un-copyedited version of an article
published in Journal of Physics B: Atomic, Molecular and Optical Physics. IOP
Publishing Ltd is not responsible for any errors or omissions in this version
of the manuscript or any version derived from it. The Version of Record is
available online at http://dx.doi.org/10.1088/0953-4075/48/21/21400
Hydraulic characteristics of porous media
CER62RHB59.October 1962.Non-funded contributing project of the Western Regional Research Committee, Project W-51, Drainage Design for Irrigation Agriculture
Hydraulic properties of porous media
March 1964.Includes bibliographical references (page 20)
Effect of stratification on relative permeability
CER56ATC25.December, 1956.Technical note 393.Journal of petroleum technology, 1956
Pressure distribution during steady flow in unsaturated sands
CER59VHS17.May 29, 1959.Includes bibliographical references.A differential equation is derived which describes the pressure distribution during steady flow in a porous material occupied by two immiscible fluids such as air and water. It is assumed that Darcy's equation applies simultaneously to the wetting and the non-wetting phase. Each phase is assumed continuous, and therefore, any isolated portions of either phase must be regarded as part of the porous matrix. The equation may be applied to fluids flowing in any direction with respect to each other or in any direction with respect to the earth's gravitational field. In order to solve the equation, it is necessary to know the relationship between the pressure discontinuity across interfaces between the phases and the conductivity of the flowing phase or phases. The nature of this function and a method of obtaining it are discussed briefly. Experiments were conducted using a hydrocarbon liquid as the wetting fluid, air as the non-wetting fluid, and long columns of sand as porous media. Several cases were investigated, and results of two are presented: (1) Downward flow through a uniform sand, and (2) Downward flow through a sand into another sand of finer texture. Good agreement between experimental data and theory was obtained for all cases
A Survey for Transient Astronomical Radio Emission at 611 MHz
We have constructed and operated the Survey for Transient Astronomical Radio
Emission (STARE) to detect transient astronomical radio emission at 611 MHz
originating from the sky over the northeastern United States. The system is
sensitive to transient events on timescales of 0.125 s to a few minutes, with a
typical zenith flux density detection threshold of approximately 27 kJy. During
18 months of around-the-clock observing with three geographically separated
instruments, we detected a total of 4,318,486 radio bursts. 99.9% of these
events were rejected as locally generated interference, determined by requiring
the simultaneous observation of an event at all three sites for it to be
identified as having an astronomical origin. The remaining 3,898 events have
been found to be associated with 99 solar radio bursts. These results
demonstrate the remarkably effective RFI rejection achieved by a coincidence
technique using precision timing (such as GPS clocks) at geographically
separated sites. The non-detection of extra-solar bursting or flaring radio
sources has improved the flux density sensitivity and timescale sensitivity
limits set by several similar experiments in the 1970s. We discuss the
consequences of these limits for the immediate solar neighborhood and the
discovery of previously unknown classes of sources. We also discuss other
possible uses for the large collection of 611 MHz monitoring data assembled by
STARE.Comment: 24 pages, 6 figures; to appear in PAS
Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization.
RRx-001, an experimental systemically non-toxic epi-immunotherapeutic agent, which potentiates the resensitization of resistant cancer cells to formerly effective therapies, is under active investigation in several clinical trials that are based on sequential or concomitant rechallenge to resistant first- or second-line regimens. One of these trials is designated TRIPLE THREAT (NCT02489903), because it explores the conditioning or priming effect of RRx-001 on three tumor types - non-small cell lung cancer (NSCLC), small cell lung cancer and high-grade neuroendocrine tumors - prior to re-administration of platinum doublets. In follow-up to a recent case study, which describes early monotherapeutic benefit with RRx-001 in a refractory EGFR-mutated NSCLC tumor, we present subsequent evidence of a radiological partial response to reintroduced platinum doublets after RRx-001. For the 50% of patients with EGFR-mutated NSCLC who progress on EGFR-tyrosine kinase inhibitors (without evidence of a T790M mutations) as well as platinum doublets and pemetrexed/taxane, no other clinically established treatment options exist. A retrial of these therapies in EGFR-positive NSCLC patients via priming with epigenetic agents such as RRx-001 constitutes a strategy to 'episensitize' tumors (i.e. reverse resistance by epigenetic means) and to extend overall survival
Pulmonary Tumor Thrombotic Microangiopathy : A New Paraneoplastic Syndrome
This report, based on data from a clinical case, proposes that pulmonary tumor thrombotic microangiopathy, an underdiagnosed cause of pulmonary hypertension and death in patients with adenocarcinoma, is a paraneoplastic syndrome (PNS). Clinicians in general must be alert to the presence or development of PNS that may precede, coincide with, follow, or herald the recurrence or the primary diagnosis of malignancy since early recognition facilitates prompt diagnosis and treatment.Peer reviewe
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