Cooldown time for simple cryogenic pipelines

Cooldown time for simple cryogenic pipeline

Development and Testing of a 2-D Transfer CCD

This paper describes the development, operation, and characterization of charge-coupled devices (CCDs) that feature an electrode structure that allows the transfer of charge both horizontally and vertically through the image area. Such devices have been termed two-dimensional (2-D) transfer CCDs (2DT CCDs), as opposed to the conventional devices, which might be called one-dimensional transfer CCDs, but in other respects are the same as conventional CCD devices. Batches of two different 2DT CCD test devices, featuring different electrode structures but with identical clocking operation in each case, were produced and tested. The methodology of 2-D charge transfer in each of the device types is described, followed by a presentation of test results from the new CCDs. The ability of both 2DT CCD transfer electrode schemes to successfully transfer charge in both horizontal and vertical directions in the image section of the devices has been proven, opening up potential new applications for 2DT CCD use

Distribution and Status of the Brazilian Free-tailed Bat (Tadarida brasiliensis cynocephala) in Arkansas

Investigations of building infestations, mist netting activities, and specimens submitted to the Arkansas Department of Health document the Brazilian free-tailed bat to be found in 14 Arkansas counties. Both overwintering and maternity colonies were examined. Numbers of individuals ranged from one to several thousand

Flex, an X-linked female-lethal mutation in Drosophila melanogaster controls the expression of sex-lethal

The Sex-lethal (Sxl) gene is required in Drosophila females for sexual differentiation of the soma, for gem cell differentiation and dosage compensation. We have isolated three new alleles of female-lethal-on-X (flex), an X-linked female-lethal mutation and have characterized its function in sex determination. SXL protein is missing in flex/flex embryos, however transcription from both Sxl(Pe), the early Sxl promoter and Sxl(Pm), the late maintenance promoter, is normal in flex homozygotes. In flex/flex embryos, Sxl mRNA is spliced in the male mode. Analysis of flex germline clones shows that it also functions in oogenesis, but in contrast to Sxl mutants that show an early arrest tumorous phenotype, flex mutant egg chambers develop to stage 10. In flex ovarian clones, Sxl RNA is also spliced in the male form. Hence, flex is a sex-specific regulator of Sxl functioning in both the soma and the germline. Genetic interaction studies show that flex does not enhance female lethality of Sxl loss-of-function alleles but it rescues the male-specific lethality of both of the gain-of-function Sxl mutations, Sxl(M1)and Sxl(M4.) In contrast to mutations in splicing regulators of Sxl, the female lethality of flex is not rescued by either Sxl(M1)or Sxl(M4). Based on these observations, we propose that flex regulates Sxl at a post-splicing stage and regulates either its translation or the stability of the SXL protein

Patients' Perceptions and Experiences of Shared Decision-Making in Primary HIV Care Clinics

Shared decision-making (SDM) is considered best practice in health care. Prior studies have explored attitudes and barriers/facilitators to SDM, with few specific to HIV care. We interviewed 53 patients in HIV primary care clinics in California to understand the factors and situations that may promote or hinder engagement in SDM. Studies in other populations have found that patients' knowledge about their diseases and their trust in providers facilitated SDM. We found these features to be more nuanced for HIV. Perceptions of personal agency, knowledge about one's disease, and trust in provider were factors that could work for or against SDM. Overall, we found that participants described few experiences of SDM, especially among those with no comorbidities. Opportunities for SDM in routine HIV care (e.g., determining antiretroviral therapy) may arise infrequently because of treatment advances. These findings yield considerations for adapting SDM to fit the context of HIV care

Bat Fauna of Southeast Arkansas

A systematic survey of the mammalian fauna of Southwest Arkansas has resulted in the accumulation of more than 200 records of bats from the 21 counties comprising the study area. The records reveal distributional patterns for 12 species of bats and represent a total of 68 new county records for this area of Arkansas

A distributed data component for the Open Modeling Interface

As the volume of collected data continues to increase in the environmental sciences, so too does the need for effective means for accessing those data. We have developed an Open Modeling Interface (OpenMI) data component that retrieves input data for model components from environmental information systems and delivers output data to those systems. The adoption of standards for both model component input–output interfaces and web services make it possible for the component to be reconfigured for use with different linked models and various online systems. The data component employs three techniques tailored to the unique design of the OpenMI that enable efficient operation: caching, prefetching, and buffering, making it capable of scaling to large numbers of simultaneous simulations executing on a computational grid. We present the design of the component, an evaluation of its performance, and a case study demonstrating how it can be incorporated into modeling studies

Cooldown of Cryogenic Transfer Lines an Experimental Report

Pressure, temperature, and flow during cooldown of cryogenic transfer line