Stabilisasi Tanah Lempung Ekspansif Menggunakan Fly Ash Di Desa Oebelo Kabupaten Kupang

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan fly ash terhadap tanah lempung ekspansif Desa Oebelo dalam rangka stabilisasi tanpa melalui proses pemeraman. Parameter yang diteliti adalah sifat-sifat fisik dan mekanik tanah berupa parameter berat jenis tanah, batas-batas Atterberg, kadar air optimum dan berat volume kering maksimum dari pemadatan standar dan potensi pengembangan. Kadar fly ash yang ditambahkan pada tanah tersebut adalah sebesar 10%, 20% dan 30%. Hasil pengujian sifat fisik tanah menunjukkan kenaikan nilai berat jenis, dan penurunan nilai batas cair, batas plastis, indeks plastisitas dan peningkatan nilai batas susut tanah seiring dengan bertambah besarnya kadar fly ash dalam tanah. Penambahan kadar fly ash juga menyebabkan penurunan nilai kadar air optimum dan peningkatan nilai kepadatan kering maksimum, serta menyebabkan peningkatan nilai potensi pengembanga

Mortality-related resource utilization in the inpatient care of hypoplastic left heart syndrome.

BACKGROUND: Quantifying resource utilization in the inpatient care of congenital heart diease is clinically relevant. Our purpose is to measure the investment of inpatient care resources to achieve survival in hypoplastic left heart syndrome (HLHS), and to determine how much of that investment occurs in hospitalizations that have a fatal outcome, the mortality-related resource utilization fraction (MRRUF). METHODS: A collaborative administrative database, the Pediatric Health Information System (PHIS) containing data for 43 children\u27s hospitals, was queried by primary diagnosis for HLHS admissions of patients ≤21 years old during 2004-2013. Institution, patient age, inpatient deaths, billed charges (BC) and length of stay (LOS) were recorded. RESULTS: In all, 11,122 HLHS admissions were identified which account for total LOS of 277,027 inpatient-days and $3,928,794,660 in BC. There were 1145 inpatient deaths (10.3%). LOS was greater among inpatient deaths than among patients discharged alive (median 17 vs. 12, p \u3c 0.0001). BC were greater among inpatient deaths than among patients discharged alive (median 4.09 × 10(5) vs. 1.63 × 10(5), p \u3c 0.0001). 16% of all LOS and 21% of all BC were accrued by patients who did not survive their hospitalization. These proportions showed no significant change year-by-year. The highest volume institutions had lower mortality rates, but there was no relation between institutional volume and the MRRUF. CONCLUSIONS: These data should alert providers and consumers that current practices often result in major resource expenditure for inpatient care of HLHS that does not result in survival to hospital dismissal. They highlight the need for data-driven critical review of standard practices to identify patterns of care associated with success, and to modify approaches objectively

PELATIHAN LAS BAGI PEMUDA GEREJA TAMARISKA MAULAFA KOTA KUPANG

Generasi muda adalah agen perubahan dalam masyarakat. Kelompok ini berpeluang untuk berkontribusi positif kepada lingkungan melalui ide ide yang kreatif dan inovatif. Untuk itu generasi muda perlu dibekali dengan berbagai ketrampilan yang dapat mendukung peran sebagai agen perubahan. PKM pelatihan las ini direncanakan untuk dilaksanakan dalam suatu rangkaian kegiatan meliputi identifikasi masalah dengan mitra, Focus Group Discussion (FGD) untuk mencari solusi bersama, melaksanakan pelatihan dan workshop las dan mengaplikasikan hasil pelatihan. Sesuai dengan materi pelatihan maka dapat dikatakan hasil capaian mitra dalam implementasi hingga saat ini telah memiliki kemampuan dalam mengenal dan memahami karakteristik material yang dapat dilas, serta proses pengelasan,  menganalisa kebutuhan bahan yang diperlukan dan dapat memproduksi 1(satu) set meja

KOEFISIEN PENGALIRAN EMBUNG KECIL DI PULAU FLORES BAGIAN BARAT

Provinsi NTT memiliki empat pulau besar, salah satunya adalah Pulau Flores dengan luas wilayah ±14.000 km2 yang terbagi atas 8 kabupaten. Daerah tersebut termasuk dalam daerah dengan persebaran curah hujannya tidak merata dimana curah hujan rata-rata bulanan berkisar antara 16,669 – 354,058 mm/bulan. Penelitian ini dilakukan pada 4 kabupaten yakni Kabupaten Manggarai Barat, Manggarai, Manggarai Timur, dan Ngada. Tujuan penelitian ini untuk mengetahui perbedaan nilai koefisien pengaliran menggunakan cara analisis dan perhitungan grafik. Pada penelitian ini menggunakan data curah hujan, klimatologi dan teknis embung untuk perhitungan koefisien pengaliran dengan cara analisis dan perhitungan grafik. Cara analisis menggunakan perhitungan evapotranspirasi metode Penman modifikasi dan perhitungan debit metode F. J. Mock. Cara perhitungan grafik menggunakan data curah hujan dan data kemiringan lahan. Berdasarkan hasil perhitungan dengan menggunakan cara analisis diperoleh nilai koefisien pengaliran berkisar 0,000 – 0,355 di Manggarai Barat, 0,220 – 0,823 di Manggarai, 0,006 – 0,246 di Manggarai Timur, dan Ngada berkisar 0,162 – 0,786.NTT Province has four large islands, which one is Flores Island with an area ±14,000 km2 devided into 8 districs. These area have uneven distribution of rainfall  where the average monthly rainfall ranges from 16.669 – 354.058 mm/month. The research was conducted in 4 districts that West Manggarai, Manggarai, East Manggarai, and Ngada. The purpose of this research is to know the difference of runoff coefficient value by using the analysis method and calculation of the runoff coefficient graph. In this study using rainfall data, climatology data and technical data of retention basin for the calculation of runoff coefficient. The analysis method uses Penman modification for evanpotranspiraton and the F. J. Mock method for analysis of dependable flow. Based on the analysis results, the runoff coefficient value ranges from 0.000 - 0,355 in West Manggarai, 0,220 - 0,823 in Manggarai, 0,006 - 0,246 in East Manggarai and Ngada around 0,162 - 0,786

Simulasi Pola Tanam Pada Sembilan Daerah Irigasi Tersebar di Kota Kupang

Kota Kupang dengan luas 180.27 km2, memiliki dua musim yaitu musim kemarau dan musim hujan. Kota Kupang memiliki 9 daerah irigasi yang terletak tersebar di Kota Kupang. Pada musim kemarau sering timbul kekeringan pada areal pertanian yang mengakibatkan gagal panen. Penelitian ini bertujuan untuk mengetahui pola tanam pada daerah irigasi di Kota Kupang yang optimal sesuai dengan keseimbangan air yang terjadi antara debit andalan dan kebutuhan air irigasi. Metode untuk menghitung evapotranspirasi digunakan metode Penman Modifikasi dan analisis debit andalan menggunakan metode F.J. Mock. Berdasarkan hasil penelitian, besar kebutuhan air irigasi yang terbesar adalah pada Daerah Irigasi Fatukoa untuk pola tanam padi-palawija-palawija sebesar 0.00-0.25 m3/dtk dan padi-padi-palawija sebesar 0.01-0.47 m3/dtk. Untuk neraca air Daerah Irigasi Fatukoa dengan pola tanam padi-palawija-palawija tahun normal (Q50) sebesar -0.25-2.39 m3/dtk dan tahun kering (Q80) sebesar -0.25-1.46 m3/dtk. Untuk 9 daerah irigasi di Kota Kupang, pola tanam yang sesuai untuk tahun normal (Q50) adalah padi-palawija-palawija dan untuk tahun kering (Q80) adalah padi-palawija-palawija

Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer

Background Adjuvant gemcitabine for pancreatic cancer has limited efficacy in the clinical setting. Impaired drug metabolism is associated with treatment resistance. We aimed to evaluate the chemosensitising effect of interferon-beta (IFN-β). Methods BxPC-3, CFPAC-1, and Panc-1 cells were pre-treated with IFN-β followed by gemcitabine monotherapy. The effect on cell growth, colony formation, and cell cycle was determined. RT-qPCR was used to measure gene expression. BxPC-3 cells were used in a heterotopic subcutaneous mouse model. Results IFN-β increased sensitivity to gemcitabine (4-, 7.7-, and 1.7-fold EC50 decrease in BxPC-3, CFPAC-1, and Panc-1, respectively; all P < 0.001). Findings were confirmed when assessing colony formation. The percentage of cells in the S-phase was significantly increased after IFN-β treatment only in BxPC-3 and CFPAC-1 by 12 and 7%, respectively (p < 0.001 and p < 0.05, respectively). Thereby, IFN-β upregulated expression of the drug transporters SLC28A1 in BxPC-3 (252%) and SLC28A3 in BxPC-3 (127%) and CFPAC-1 (223%) (all p < 0.001). In vivo, combination therapy reduced tumor

Management in non-traumatic arm, neck and shoulder complaints: differences between diagnostic groups

Arm, neck and/or shoulder complaints are common in western societies. In the Netherlands, general practice guidelines are issued on shoulder pain and epicondylitis only. Little is known about actual management of the total range of diagnoses. The objectives of the study are: to determine management in patients consulting the GP with a new episode of non-traumatic arm neck and shoulder complaints up to 6 months after the first consultation. To evaluate differences in management between patients with specific diagnoses versus non-specific diagnoses and between specific diagnostic groups. In a prospective cohort study in general practice. We recruited 682 eligible patients. Data on diagnosis, management, patient- and complaint-characteristics were collected. Co-occurrence of treatment options was presented in scaled rectangles. After 6 months, additional diagnostic tests had been performed in 18% of the patients, mainly radiographic examination (14%). Further, 49% had been referred for physiotherapy and 12% to the medical specialist. Patients with specific diagnoses were more frequently referred for specialist treatment, and patients with non-specific diagnoses for physiotherapy. Corticosteroid injections (17%) were mainly applied specific diagnoses (e.g. impingement syndrome, frozen shoulder, carpal tunnel and M. Quervain). Frequencies of prescribed medication (51%) did not differ between specific and non-specific

Revival of the magnetar PSR J1622-4950: observations with MeerKAT, Parkes, XMM-Newton, Swift, Chandra, and NuSTAR

New radio (MeerKAT and Parkes) and X-ray (XMM-Newton, Swift, Chandra, and NuSTAR) observations of PSR J1622-4950 indicate that the magnetar, in a quiescent state since at least early 2015, reactivated between 2017 March 19 and April 5. The radio flux density, while variable, is approximately 100x larger than during its dormant state. The X-ray flux one month after reactivation was at least 800x larger than during quiescence, and has been decaying exponentially on a 111+/-19 day timescale. This high-flux state, together with a radio-derived rotational ephemeris, enabled for the first time the detection of X-ray pulsations for this magnetar. At 5%, the 0.3-6 keV pulsed fraction is comparable to the smallest observed for magnetars. The overall pulsar geometry inferred from polarized radio emission appears to be broadly consistent with that determined 6-8 years earlier. However, rotating vector model fits suggest that we are now seeing radio emission from a different location in the magnetosphere than previously. This indicates a novel way in which radio emission from magnetars can differ from that of ordinary pulsars. The torque on the neutron star is varying rapidly and unsteadily, as is common for magnetars following outburst, having changed by a factor of 7 within six months of reactivation.Comment: Published in ApJ (2018 April 5); 13 pages, 4 figure

Evidence of contamination by oil and oil products in the Santos-Sao Vicente estuary, Sao Paulo, Brazil

Different components of the mixed function oxidase (MFO) system and the levels of fluorescent aromatic compounds in bile (FACs) were measured in Cathorops spixii in order to assess the impact of polycyclic aromatic hydrocarbons (PAHs). Fish were sampled in an estuary (Santos/Sao Vicente) with a history of contamination by PAHs, mainly due to the presence of the industrial complex of Cubatao city and of another of low anthropogenic influence (Cananeia) on the Brazilian coast. FACs were higher in fish from the polluted site, and the PAH 5 and 6-ring metabolites were the most frequent - with 14% and 15%, respectively. Levels of the different components of the MFO system showed the same variation profile as the FACs for both estuaries. Therefore, the values found for somatic indexes and biomarkers with data of bile PAH metabolites indicate the presence of organic contaminants, especially in the area subject to the influence of the industrial complex on the Santos/Sao Vicente estuary.CAPES (Brazilian Agency for Science and Technology); Oceanographic Institute of Sao Paulo University; Laboratory of Ecotoxicology and Environmental Chemistry of the University of Algarve; CAPES-PDEE [BEX 2176/07-6]info:eu-repo/semantics/publishedVersio