137 research outputs found

    Soaring Migratory Birds Avoid Wind Farm in the Isthmus of Tehuantepec, Southern Mexico

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    Funding: This research was made possible with funding from the World Bank to the Comisión Federal de Electricidad (CFE) for monitoring the environmental impacts of the wind farm. The funders of this study were the CFE. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

    A Plasmodium promiscuous T cell epitope delivered within the Ad5 hexon protein enhances the protective efficacy of a protein based malaria vaccine

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    A malaria vaccine is a public health priority. In order to produce an effective vaccine, a multistage approach targeting both the blood and the liver stage infection is desirable. The vaccine candidates also need to induce balanced immune responses including antibodies, CD4+ and CD8+ T cells. Protein-based subunit vaccines like RTS,S are able to induce strong antibody response but poor cellular reactivity. Adenoviral vectors have been effective inducing protective CD8+ T cell responses in several models including malaria; nonetheless this vaccine platform exhibits a limited induction of humoral immune responses. Two approaches have been used to improve the humoral immunogenicity of recombinant adenovirus vectors, the use of heterologous prime-boost regimens with recombinant proteins or the genetic modification of the hypervariable regions (HVR) of the capsid protein hexon to express B cell epitopes of interest. In this study, we describe the development of capsid modified Ad5 vectors that express a promiscuous Plasmodium yoelii T helper epitope denominated PyT53 within the hexon HVR2 region. Several regimens were tested in mice to determine the relevance of the hexon modification in enhancing protective immune responses induced by the previously described protein-based multi-stage experimental vaccine PyCMP. A heterologous prime-boost immunization regime that combines a hexon modified vector with transgenic expression of PyCMP followed by protein immunizations resulted in the induction of robust antibody and cellular immune responses in comparison to a similar regimen that includes a vector with unmodified hexon. These differences in immunogenicity translated into a better protective efficacy against both the hepatic and red blood cell stages of P. yoelii. To our knowledge, this is the first time that a hexon modification is used to deliver a promiscuous T cell epitope. Our data support the use of such modification to enhance the immunogenicity and protective efficacy of adenoviral based malaria vaccines

    The alhambra photometric system

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    This paper presents the characterization of the optical range of the ALHAMBRA photometric system, a 20 contiguous, equal-width, medium-band CCD system with wavelength coverage from 3500 Å to 9700 Å. The photometric description of the system is done by presenting the full response curve as a product of the filters, CCD, and atmospheric transmission curves, and using some first- and second-order moments of this response function. We also introduce the set of standard stars that defines the system, formed by 31 classic spectrophotometric standard stars which have been used in the calibration of other known photometric systems, and 288 stars, flux calibrated homogeneously, from the Next Generation Spectral Library (NGSL). Based on the NGSL, we determine the transformation equations between Sloan Digital Sky Survey ugriz hotometry and the ALHAMBRA photometric system, in order to establish some relations between both systems. Finally, we develop and discuss a strategy to calculate the photometric zero points of the different pointings in the ALHAMBRA project.Ministerio de Educación y Ciencia AYA2006-14056 BES-2007-1476

    Stellar physics with the ALHAMBRA photometric system

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    The ALHAMBRA photometric system was specifically designed to perform a tomography of the Universe in some selected areas. Although mainly designed for extragalactic purposes, its 20 contiguous, equal-width, medium-band photometric system in the optical wavelength range, shows a great capacity for stellar classification. In this contribution we propose a methodology for stellar classification and physical parameter estimation (Teff, log g, [Fe/H], and color excess E(B - V)) based on 18 independent reddening-free Q-values from the ALHAMBRA photometry. Based on the theoretical Spectral library BaSeL 2.2, and applied to 288 stars from the Next Generation spectral Library (NGSL), we discuss the reliability of the method and its dependence on the extinction law used

    Stellar populations of galaxies in the ALHAMBRA survey up to z1z \sim 1. II. Stellar content of quiescent galaxies within the dust-corrected stellar mass-colour and the UVJUVJ colour-colour diagrams

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    Our aim is to determine the distribution of stellar population parameters (extinction, age, metallicity, and star formation rate) of quiescent galaxies within the rest-frame stellar mass-colour and UVJUVJ colour-colour diagrams corrected for extinction up to z1z\sim1. These novel diagrams reduce the contamination in samples of quiescent galaxies owing to dust-reddened galaxies, and they provide useful constraints on stellar population parameters. We set constraints on the stellar population parameters of quiescent galaxies combining the ALHAMBRA multi-filter photo-spectra with our SED-fitting code MUFFIT, making use of composite stellar population models. The extinction obtained by MUFFIT allowed us to remove dusty star-forming (DSF) galaxies from the sample of red UVJUVJ galaxies. The distributions of stellar population parameters across these rest-frame diagrams are revealed after the dust correction and are fitted by the LOESS method to reduce uncertainty effects. Quiescent galaxy samples defined via classical UVJUVJ diagrams are typically contaminated by a 20\sim20% fraction of DSF galaxies. A significant part of the galaxies in the green valley are actually obscured star-forming galaxies (3065\sim30-65%). Consequently, the transition of galaxies from the blue cloud to the red sequence, and hence the related mechanisms for quenching, seems to be much more efficient and faster than previously reported. The rest-frame stellar mass-colour and UVJUVJ colour-colour diagrams are useful for constraining the age, metallicity, extinction, and star formation rate of quiescent galaxies by only their redshift, rest-frame colours, and/or stellar mass. Dust correction plays an important role in understanding how quiescent galaxies are distributed in these diagrams and is key to performing a pure selection of quiescent galaxies via intrinsic colours.Comment: (37 pages, 29 figures, accepted for publication in A&A

    Stellar populations of galaxies in the ALHAMBRA survey up to z1z \sim 1. I. MUFFIT: A Multi-Filter Fitting code for stellar population diagnostics

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    We present MUFFIT, a new generic code optimized to retrieve the main stellar population parameters of galaxies in photometric multi-filter surveys, and we check its reliability and feasibility with real galaxy data from the ALHAMBRA survey. Making use of an error-weighted χ2\chi^2-test, we compare the multi-filter fluxes of galaxies with the synthetic photometry of mixtures of two single stellar populations at different redshifts and extinctions, to provide through a Monte Carlo method the most likely range of stellar population parameters (mainly ages and metallicities), extinctions, redshifts, and stellar masses. To improve the diagnostic reliability, MUFFIT identifies and removes from the analysis those bands that are significantly affected by emission lines. We highlight that the retrieved age-metallicity locus for a sample of z0.22z \le 0.22 early-type galaxies in ALHAMBRA at different stellar mass bins are in very good agreement with the ones from SDSS spectroscopic diagnostics. Moreover, a one-to-one comparison between the redshifts, ages, metallicities, and stellar masses derived spectroscopically for SDSS and by MUFFIT for ALHAMBRA reveals good qualitative agreements in all the parameters. In addition, and using as input the results from photometric-redshift codes, MUFFIT improves the photometric-redshift accuracy by 10\sim 10-20%20\%, and it also detects nebular emissions in galaxies, providing physical information about their strengths. Our results show the potential of multi-filter galaxy data to conduct reliable stellar population studies with the appropiate analysis techniques, as MUFFIT.Comment: 31 pages, 18 figures, accepted for publication in A&

    The ALHAMBRA survey: Accurate merger fractions by PDF analysis of photometric close pairs

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    Our goal is to develop and test a novel methodology to compute accurate close pair fractions with photometric redshifts. We improve the current methodologies to estimate the merger fraction f_m from photometric redshifts by (i) using the full probability distribution functions (PDFs) of the sources in redshift space, (ii) including the variation in the luminosity of the sources with z in both the selection of the samples and in the luminosity ratio constrain, and (iii) splitting individual PDFs into red and blue spectral templates to deal robustly with colour selections. We test the performance of our new methodology with the PDFs provided by the ALHAMBRA photometric survey. The merger fractions and rates from the ALHAMBRA survey are in excellent agreement with those from spectroscopic work, both for the general population and for red and blue galaxies. With the merger rate of bright (M_B <= -20 - 1.1z) galaxies evolving as (1+z)^n, the power-law index n is larger for blue galaxies (n = 2.7 +- 0.5) than for red galaxies (n = 1.3 +- 0.4), confirming previous results. Integrating the merger rate over cosmic time, we find that the average number of mergers per galaxy since z = 1 is N_m = 0.57 +- 0.05 for red galaxies and N_m = 0.26 +- 0.02 for blue galaxies. Our new methodology exploits statistically all the available information provided by photometric redshift codes and provides accurate measurements of the merger fraction by close pairs only using photometric redshifts. Current and future photometric surveys will benefit of this new methodology.Comment: Submitted to A&A, 15 pages, 15 figures, 6 tables. Comments are welcome. Close pair systems available at https://cloud.iaa.csic.es/alhambra/catalogues/ClosePairs

    The ALHAMBRA survey : Estimation of the clustering signal encoded in the cosmic variance

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    The relative cosmic variance (σv\sigma_v) is a fundamental source of uncertainty in pencil-beam surveys and, as a particular case of count-in-cell statistics, can be used to estimate the bias between galaxies and their underlying dark-matter distribution. Our goal is to test the significance of the clustering information encoded in the σv\sigma_v measured in the ALHAMBRA survey. We measure the cosmic variance of several galaxy populations selected with BB-band luminosity at 0.35z<1.050.35 \leq z < 1.05 as the intrinsic dispersion in the number density distribution derived from the 48 ALHAMBRA subfields. We compare the observational σv\sigma_v with the cosmic variance of the dark matter expected from the theory, σv,dm\sigma_{v,{\rm dm}}. This provides an estimation of the galaxy bias bb. The galaxy bias from the cosmic variance is in excellent agreement with the bias estimated by two-point correlation function analysis in ALHAMBRA. This holds for different redshift bins, for red and blue subsamples, and for several BB-band luminosity selections. We find that bb increases with the BB-band luminosity and the redshift, as expected from previous work. Moreover, red galaxies have a larger bias than blue galaxies, with a relative bias of brel=1.4±0.2b_{\rm rel} = 1.4 \pm 0.2. Our results demonstrate that the cosmic variance measured in ALHAMBRA is due to the clustering of galaxies and can be used to characterise the σv\sigma_v affecting pencil-beam surveys. In addition, it can also be used to estimate the galaxy bias bb from a method independent of correlation functions.Comment: Astronomy and Astrophysics, in press. 9 pages, 4 figures, 3 table
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