1,922 research outputs found

    The Relationship Between Perfectionism and Goal Orientation Among Gifted Students in the King Abdullah II School of Excellence

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    This study aimed to find out the relationship between Perfectionism and Goal Orientation among Gifted Students in the King Abdullah II School of Excellence. It also aimed at finding out if the relationship between Perfectionism and Goal Orientation is different according to the level of education and gender. To achieve the objectives of the study, Perfectionism and Goal Orientation scales were developed by the researchers. The sample of the study consisted of 184 students at seventh and eighth grades in the King Abdullah II School of Excellence. They were randomly stratified selected from the students population. The results of the study indicated that the level of Perfectionism among the gifted students was high, and the study showed that the level of the types of goal orientation was high, specifically Mastery goal oriented. The results also indicated there was no statistically significant difference at the significance level (α=0.05) in the strength of the correlation between Perfectionism and the types of goal orientation due to the level of education. The results also indicated there was no statistically significant difference at the significance level (α=0.05) in the strength of the correlation between Perfectionism and the types of Goal Orientation due to gender

    The Effectiveness of an Educational Program for Developing Tolerance Values and Resistance to Intellectual Extremism at Secondary Level in Jordan

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    This study aimed to establish an effective educational program based on the rights of non-Muslims in Islamic principles of the development of religious tolerance values and the intellectual resistance of extremism among high school students in Jordan. The study was conducted on a sample of 48 students in 11th grade from Al-Arqam Islamic School, during the second semester of the academic year 2017-2018. A descriptive method was used for gathering the principles of rights for non-Muslims. A semi-empirical method was also used to measure the effectiveness of the educational program on two dependent variables (religious tolerance values, resistance of intellectual extremism), measured with two tools prepared by the researchers: the measure of religious tolerance values, and the measure of resistance to intellectual extremism. The results showed a statistically significant difference between the average performance of both the experimental and control groups in the measures for religious tolerance and resistance to intellectual extremism due to the experimental method of teaching designed for this study

    Novel roles for mucin 1 in the kidney

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    Purpose of review Recent studies in the kidney have revealed that the well characterized tumor antigen mucin 1 (MUC1/Muc1) also has numerous functions in the normal and injured kidney. Recent findings Mucin 1 is a transmembrane mucin with a robust glycan-dependent apical targeting signal and efficient recycling from endosomes. It was recently reported that the TRPV5 calcium channel is stabilized on the cell surface by galectin-dependent cross-linking to mucin 1, providing a novel mechanism for regulation of ion channels and normal electrolyte balance. Our recent studies in mice show that Muc 1 is induced after ischemia, stabilizing hypoxia-inducible factor 1 (HIF-1)α and ÎČ-catenin levels, and transactivating the HIF-1 and ÎČ-catenin protective pathways. However, prolonged induction of either pathway in the injured kidney can proceed from apparent full recovery to chronic kidney disease. A very recent report indicates that aberrant activation of mucin 1 signaling after ischemic injury in mice and humans is associated with development of chronic kidney disease and fibrosis. A frameshift mutation in MUC1 was recently identified as the genetic lesion causing medullary cystic kidney disease type 1, now appropriately renamed MUC1 Kidney Disease. Summary Studies of mucin 1 in the kidney now reveal significant functions for the extracellular mucin-like domain and signaling through the cytoplasmic tail

    Ballota saxatilis from Jordan: Evaluation of Essential Oil Composition and Phytochemical Profiling of Crude Extracts and Their In-Vitro Antioxidant Activity

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    The chemical composition of essential oil extracted from the aerial parts of Ballota saxatilis Sieber ex C.Presl from Jordan has been elucidated by gas chromatography–mass spectrometry (GC-MS). Additionally, aqueous methanol (BsA), Butanol (BsB) and water (BsW) extracts were screened for their total phenol content (TPC), total flavonoid content (TFC), and antioxidant activities using the 2,2 Diphenyl-1-picrylhydrazyl (DPPH) and 2,2-Azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) diammonium salt (ABTS) methods. The most potent extracts were screened for their phenolic acids and flavonoid content using liquid the chromatography–mass spectrometry (LC-MS) technique. The results indicated that the essential oil predominantly contained cis-pinane (14.76%), ÎČ-caryophyllene (8.91%) and allo-aromadendrene epoxide (6.39%). Among the different extracts investigated, the BsB fraction had the most TPC and TFC (455.79 ± 1.03 ”g gallic acid/g dry extract; 272.62 ± 8.28 ”g quercetin/g dry extract, respectively) and had the best radical and radical cation scavenging activities, as determined using the DPPH and ABTS methods. Quantitative and qualitative LC-MS analyses of BsA and BsB using LC-MS revealed each of the kaempferol-3-O-rutinoside (30.29%), chrysoeriol-7-glucoside (7.93%) and luteolin 7-o-glucoside (7.76%) as the main constituents of the BsA fraction. The BsB fraction was rich in 7,4â€Č-dimethoxy-3-hydroxyflavone (34.68%), kaempferol-3,7,4â€Č-trimethyl ether (29.17%) and corymbosin (9.66%) and lower concentration levels of kaempferol-3-O-rutinoside (1.63%) and chrysoeriol-7-glucoside (0.51%)

    Altered respiratory microbiota composition and functionality associated with asthma early in life

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    BACKGROUND: The microbiota of the respiratory tract has an important role in maintaining respiratory health. However, little is known on the respiratory microbiota in asthmatic patients among Middle Eastern populations. This study investigated the respiratory microbiota composition and functionality associated with asthma in Emirati subjects. METHODS: We performed 16S rRNA and ITS2-gene based microbial profiling of 40 expectorated sputum samples from adult and pediatric Emirati individuals averaging 52 and 7 years of age, respectively with or without asthma. RESULTS: We report bacterial difference belonging to Bacteroidetes, Firmicutes, Fusobacteria and Proteobacteria phyla between asthmatic and non-asthmatic controls. Similarly, fungal difference belonging to Ascomycota, Basidiomycota phyla and other unclassified fungi. Differential abundance testing among asthmatic individuals with relation to Asthma Control Test show a significant depletion of Penicillium aethiopicum and Alternaria spp., among poorly controlled asthmatics. Moreover, data suggest a significant expansion of Malassezia spp. and other unclassified fungi in the airways of those receiving steroids and leukotriene receptor antagonists’ combination therapy, in contrast to those receiving steroids alone. Functional profiling from 16S data showed marked differences between pediatric asthmatic and non-asthmatic controls, with pediatric asthmatic patients showing an increase in amino acid (p-value < 5.03 × 10− 7), carbohydrate (p-value < 4.76 × 10− 7), and fatty acid degradation (p-value < 6.65 × 10− 7) pathways, whereas non-asthmatic controls are associated with increase in amino acid (p-value < 8.34 × 10− 7), carbohydrate (p-value < 3.65 × 10− 7), and fatty acid (p-value < 2.18 × 10− 6) biosynthesis pathways in concordance with enterotype composition. CONCLUSIONS: These differences provide an insight into respiratory microbiota composition in Emirati population and its possible role in the development of asthma early in life. This study provides important information that may eventually lead to the development of screening biomarkers to predict early asthma development and novel therapeutic approaches

    Measurement and ab initio Investigation of Structural, Electronic, Optical, and Mechanical Properties of Sputtered Aluminum Nitride Thin Films

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    We report our results on highly textured aluminum nitride (AlN) thin films deposited on glass substrates, oriented along the c-axis, using DC-magnetron sputtering technique for different values of back pressure. The structural, electronic, optical, piezoelectric, dielectric, and elastic properties of sputtered AlN thin films are measured and characterized. In particular, X-ray powder diffraction (XRD) technique shows that AlN thin films exhibit a hexagonal structure. Moreover, we employed ab initio simulations of AlN using the Vienna Ab Initio Simulation Package (VASP) to investigate the structural and the electronic properties of hexagonal AlN structures. The experimental lattice parameters of the as-prepared thin films agree well with those calculated using the total energy minimization approach. The optical parameters of AlN thin films, such as transmittance and refractive index, were measured using UV–vis measurements. Our measurements of refractive index, n, of AlN thin films yield a value of 2.2. Furthermore, the elastic, piezoelectric, and dielectric tensors of AlN crystal are calculated using VASP. The dynamical Born effective charge tensor is reported for all atoms in the unit cell of AlN. Interestingly, ab initio simulations indicate that AlN has a static dielectric constant approximately equal to 4.68, which is in good agreement with the reported experimental value. In addition, the clamped-ion piezoelectric tensor is calculated. The diagonal components of the piezoelectric tensor are found to be e33=1.79 C/m2 and e31=−0.80 C/m2. The large values of the piezoelectric coefficients show that a polar AlN crystal exhibits a strong microwave piezoelectric effect. Additionally, the components of the elastic moduli tensor are calculated. The extraordinary electronic, optical, piezoelectric, and elastic properties make AlN thin films potential candidates for several optoelectronic, elastic, dielectric, and piezoelectric applications

    Extremal number of theta graphs of order 7

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    For a set of graphsF, letH(n;F) denote the class of non-bipartiteHamiltonian graphs onnvertices that does not contain any graph ofFas a subgraphandh(n;F) = max{E(G) :G∈H(n;F)}whereE(G) is the number of edges inG.In this paper we determineh(n;{Ξ4, Ξ5, Ξ7}) andh(n;Ξ7) for sufficiently odd largen. Our result confirms the conjecture made in [1] fork= 3.Scopu
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