Supporting research studies to booster flight control problems Final report

Asymptotic stability and response of nonlinear system

Evidence that a Panel of Neurodegeneration Biomarkers Predicts Vasospasm, Infarction, and Outcome in Aneurysmal Subarachnoid Hemorrhage

Biomarkers for neurodegeneration could be early prognostic measures of brain damage and dysfunction in aneurysmal subarachnoid hemorrhage (aSAH) with clinical and medical applications. Recently, we developed a new panel of neurodegeneration biomarkers, and report here on their relationships with pathophysiological complications and outcomes following severe aSAH. Fourteen patients provided serial cerebrospinal fluid samples for up to 10 days and were evaluated by ultrasonography, angiography, magnetic resonance imaging, and clinical examination. Functional outcomes were assessed at hospital discharge and 6–9 months thereafter. Eight biomarkers for acute brain damage were quantified: calpain-derived α-spectrin N- and C-terminal fragments (CCSntf and CCSctf), hypophosphorylated neurofilament H

Assessment of Window Types in Natural Ventilation of Hotels in Taraba State

Natural ventilation provides the needed amount of good air quality through a natural process of allowing air in and out of buildings through the windows in order to achieve thermal comfort. There has been poor ventilation problem in hotels due to choice of windows which causes sick building syndrome. This research is aimed at specifying window types for effective ventilation in hotels. This is to be achieved through ascertaining of the window types used in hotels, ascertaining the window sizes used in hotels and to analyse the various window types in order to specify the effective types for hotels. In carrying out the objectives, two hotels were selected from each of the three senatorial zones in Taraba State where primary data were collected from a total of six selected hotels through direct observation. Secondary data in relation to natural ventilation and window types were gotten through review of literature. The data collected were analysed, using descriptive statistics. Findings and deduction were made. The concluding part of this research highlights the need and importance of using window types that provide the maximum ventilation in hotel rooms and other spaces. Recommendations were made for windows with high ventilation percentage to be used in hotels for effective ventilation. Keywords: Hotel, Natural Ventilation, Sick building syndrome, thermal comfort, windo

CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation

Corticostriatal circuits mediate various aspects of goal-directed behavior and are critically important for basal ganglia-related disorders. Activity in these circuits is regulated by the endocannabinoid system via stimulation of CB1 cannabinoid receptors. CB1 receptors are highly expressed in projection neurons and select interneurons of the striatum, but expression levels vary considerably between different striatal regions (functional domains). We investigated CB1 receptor expression within specific corticostriatal circuits by mapping CB1 mRNA levels in striatal sectors defined by their cortical inputs in rats. We also assessed changes in CB1 expression in the striatum during development. Our results show that CB1 expression is highest in juveniles (P25) and then progressively decreases toward adolescent (P40) and adult (P70) levels. At every age, CB1 receptors are predominantly expressed in sensorimotor striatal sectors, with considerably lower expression in associative and limbic sectors. Moreover, for most corticostriatal circuits there is an inverse relationship between cortical and striatal expression levels. Thus, striatal sectors with high CB1 expression (sensorimotor sectors) tend to receive inputs from cortical areas with low expression, while striatal sectors with low expression (associative/limbic sectors) receive inputs from cortical regions with higher expression (medial prefrontal cortex). In so far as CB1 mRNA levels reflect receptor function, our findings suggest differential CB1 signaling between different developmental stages and between sensorimotor and associative/limbic circuits. The regional distribution of CB1 receptor expression in the striatum further suggests that, in sensorimotor sectors, CB1 receptors mostly regulate GABA inputs from local axon collaterals of projection neurons, whereas in associative/limbic sectors, CB1 regulation of GABA inputs from interneurons and glutamate inputs may be more important

Efficient FPGA Hardware Reuse in a Multiplierless Decimation Chain

In digital communications, an usual reception chain requires many stages of digital signal processing for filtering and sample rate reduction. For satellite on board applications, this need is hardly constrained by the very limited hardware resources available in space qualified FPGAs. This short paper focuses on the implementation of a dual chain of 14 stages of cascaded half band filters plus 2 : 1 decimators for complex signals (in-phase and quadrature) with minimal hardware resources, using a small portion of an UT6325 Aeroflex FPGA, as a part of a receiver designed for a low data rate command and telemetry channel

A economia institucional: em busca de uma teoria do desenvolvimento rural

This essay approaches the matter of rural development from a contemporary focus inside the economic development theory of development in an effort to take this theory more realistic and to try to explain the economical process or the different paths in differentiated historical contexts. Among those approaches are the New Institutional Economy and the New Evolutionary Economy, both of that searching to demonstrate the need of changes in the neoclassic theory of development, as it omits important elements that explain the distinct economic ways or performances of countries. The aim of this work is to demonstrate how the mentioned approaches may help to understand the distinct processes of rural development.Key words: Institucional economics, economic development, rural development.Este ensaio aborda a questão do desenvolvimento rural a partir de enfoques contemporâneos, dentro da teoria econômica do desenvolvimento, em um esforço de tornar esta teoria mais realista, e que dê conta de explicar os processos econômicos ou as diferentes trajetórias econômicas em contextos históricos diferenciados. Dentre tais abordagens destacam-se a Nova Economia Institucional e a Nova Economia Evolucionária as quais buscam demonstrar a necessidade de mudanças na teoria neoclássica do desenvolvimento, na medida em esta omite importantes elementos que explicam as distintas trajetórias ou performances econômicas dos países. O objetivo deste trabalho é o de demonstrar como as referidas abordagens podem ajudar a compreender os também distintos processos de desenvolvimento rural.Palavras-chave: Economia institucional, desenvolvimento econômico, desenvolvimento rural

A economia institucional: em busca de uma teoria do desenvolvimento rural

This essay approaches the matter of rural development from a contemporary focus inside the economic development theory of development in an effort to take this theory more realistic and to try to explain the economical process or the different paths in differentiated historical contexts. Among those approaches are the New Institutional Economy and the New Evolutionary Economy, both of that searching to demonstrate the need of changes in the neoclassic theory of development, as it omits important elements that explain the distinct economic ways or performances of countries. The aim of this work is to demonstrate how the mentioned approaches may help to understand the distinct processes of rural development.Key words: Institucional economics, economic development, rural development.Este ensaio aborda a questão do desenvolvimento rural a partir de enfoques contemporâneos, dentro da teoria econômica do desenvolvimento, em um esforço de tornar esta teoria mais realista, e que dê conta de explicar os processos econômicos ou as diferentes trajetórias econômicas em contextos históricos diferenciados. Dentre tais abordagens destacam-se a Nova Economia Institucional e a Nova Economia Evolucionária as quais buscam demonstrar a necessidade de mudanças na teoria neoclássica do desenvolvimento, na medida em esta omite importantes elementos que explicam as distintas trajetórias ou performances econômicas dos países. O objetivo deste trabalho é o de demonstrar como as referidas abordagens podem ajudar a compreender os também distintos processos de desenvolvimento rural.Palavras-chave: Economia institucional, desenvolvimento econômico, desenvolvimento rural

Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts

BACKGROUND: The magnitude of the association between Helicobacter pylori and incidence of gastric cancer is unclear. H pylori infection and the circulating antibody response can be lost with development of cancer; thus retrospective studies are subject to bias resulting from classifi- cation of cases as H pylori negative when they were infected in the past. AIMS: To combine data from all case control studies nested within prospective cohorts to assess more reliably the relative risk of gastric cancer associated with H pylori infection.To investigate variation in relative risk by age, sex, cancer type and subsite, and interval between blood sampling and cancer diagnosis. METHODS: Studies were eligible if blood samples for H pylori serology were collected before diagnosis of gastric cancer in cases. Identified published studies and two unpublished studies were included. Individual subject data were obtained for each. Matched odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated for the association between H pylori and gastric cancer. RESULTS: Twelve studies with 1228 gastric cancer cases were considered. The association with H pylori was restricted to noncardia cancers (OR 3.0; 95% CI 2.3–3.8) and was stronger when blood samples for H pylori serology were collected 10+ years before cancer diagnosis (5.9; 3.4–10.3). H pylori infection was not associated with an altered overall risk of cardia cancer (1.0; 0.7–1.4). CONCLUSIONS: These results suggest that 5.9 is the best estimate of the relative risk of non-cardia cancer associated with H pylori infection and that H pylori does not increase the risk of cardia cancer. They also support the idea that when H pylori status is assessed close to cancer diagnosis, the magnitude of the non-cardia association may be underestimated

Personal Account of a Teacher and a Student as a Component of the Electronic Information and Educational Environment of a Modern University

В статье представлены возможности личного кабинета преподавателя и студента с позиции реализации требований к функционированию электронной информационно-образовательной среды университета.The article presents the possibilities of the personal account of the teacher and the student from the point of view of the implementation of the requirements for the functioning of the electronic information and educational environment of the university