14 research outputs found
Über die Abhängigkeit des Ausfrierens von Eisenoxydhydrosolen von ihrem Aufbau und von der Gefriermethode
No full textZur Wirksamkeit des Pflege- und Sozialdienstes des Deutschen Roten Kreuzes der Deutschen Demokratischen Republik bei der Betreuung aelterer Buerger
No full textHUB (B11) - 90 HB 4368 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman
The novel arylindolylmaleimide PDA-66 displays pronounced antiproliferative effects in acute lymphoblastic leukemia cells
No full text
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells
No full textSynergistic effect of Wnt modulatory small molecules and an osteoinductive ceramic on C2C12 cell osteogenic differentiation
No full textNovel Role of Mitochondrial Manganese Superoxide Dismutase in STAT3 Dependent Pluripotency of Mouse Embryonic Stem Cells
No full textPositron emission tomography of type 2 cannabinoid receptors for detecting inflammation in the central nervous system
Full text linkCannabinoid receptor CB (CBR) is upregulated on activated microglia and astrocytes in the brain under inflammatory conditions and plays important roles in many neurological diseases, such as Alzheimer's disease, amyotrophic lateral sclerosis, and ischemic stroke. The advent of positron emission tomography (PET) using CBR radiotracers has enabled the visualization of CBR distribution in vivo in animal models of central nervous system inflammation, however translation to humans has been less successful. Several novel CBR radiotracers have been developed and evaluated to quantify microglial activation. In this review, we summarize the recent preclinical and clinical imaging results of CBR PET tracers and discuss the prospects of CBR imaging using PET
