Nicotinic Acid Adenine Dinucleotide Phosphate-induced Ca2+ Release INTERACTIONS AMONG DISTINCT Ca2+ MOBILIZING MECHANISMS IN STARFISH OOCYTES

An intracellular mechanism activated by nicotinic acid adenine dinucleotide phosphate (NAADP(+)) contributes to intracellular Ca(2+) release alongside inositol 1,4,5-trisphosphate (Ins-P(3)) and ryanodine receptors. The NAADP(+)-sensitive mechanism has been shown to be operative in sea urchin eggs, ascidian eggs, and pancreatic acinar cells. Furthermore, most mammalian cell types can synthesize NAADP(+), with nicotinic acid and NADP(+) as precursors. In this contribution, NAADP(+)-induced Ca(2+) release has been investigated in starfish oocytes. Uncaging of injected NAADP(+) induced Ca(2+) mobilization in both immature oocytes and in oocytes matured by the hormone 1-methyladenine (1-MA). The role of extracellular Ca(2+) in NAADP(+)-induced Ca(2+) mobilization, which was minor in immature oocytes, was instead essential in mature oocytes. Thus, the NAADP(+)-sensitive Ca(2+) pool, which is known to be distinct from those sensitive to inositol 1,4,5-trisphosphate or cyclic ADPribose, apparently migrated closer to (or became part of) the plasma membrane during the maturation process. Inhibition of both Ins-P(3) and ryanodine receptors, but not of either alone, substantially inhibited NAADP(+)-induced Ca(2+) mobilization in both immature and mature oocytes. The data also suggest that NAADP(+)-induced Ca(2+) mobilization acted as a trigger for Ca(2+) release via Ins-P(3) and ryanodine receptors

A complexity approach for identifying aesthetic composite landscapes

Third European Conference, EvoMUSART 2014, Granada, Spain, April 23-25, 2014, Revised Selected Papers[Abstract] The present paper describes a series of features related to complexity which may allow to estimate the complexity of an image as a whole, of all the elements integrating it and of those which are its focus of attention. Using a neural network to create a classifier based on those features an accuracy over 85% in an aesthetic composition binary classification task is achieved. The obtained network seems to be useful for the purpose of assessing the Aesthetic Composition of landscapes. It could be used as part of a media device for facilitating the creation of images or videos with a more professional aesthetic composition.Galicia. Consellería de Innovación, Industria e Comercio; PGIDIT 10TIC105008PRPortugal. Fundação para a Ciência e a Tecnologia; PTDC/EIA-EIA/115667/200

Ciclo de seminarios : el modelo sindical en debate

La publicación es el resultado del ciclo de seminarios El modelo sindical en debate, organizado por la Asociación Argentina de Especialistas en Estudios del Trabajo (ASET) y la Fundación Friedrich Ebert durante los meses de abril y mayo de 2011. El objetivo del ciclo fue contribuir a una reflexión acerca de las dimensiones sociales, culturales, históricas y legales del modelo sindical en Argentina, a la luz de los principales debates planteados en la actualidad. La publicación contiene los documentos presentados en los cuatro paneles del ciclo con la síntesis del correspondiente debate que tuvo lugar al cierre de cada panel, donde participaron reconocidos especialistas en las temáticas planteadas y actores sindicales que dieron cuenta de sus experiencias. Busca reflejar la pluralidad de posiciones existentes y algunas conclusiones que se desarrollaron en torno a las problemáticas planteadasPANEL 1: SOBRE LA VIGENCIA DEL MODELO SINDICAL ARGENTINO ¿CONTINUIDAD, REFORMA O CAMBIO? Sebastián Etchemendy ..4 PANEL 2: LA REPRESENTACIÓN SINDICAL EN LA EMPRESA. ¿UN CONCEPTO DESACTUALIZADO? Agustín Santella .. 13 PANEL 3: EL SISTEMA DE OBRAS SOCIALES Y LA COMPLEMENTARIEDAD CON EL SISTEMA PÚBLICO. ¿MODELO VIGENTE O NECESIDAD DE CAMBIO? Claudia Danani .. 34 PANEL 4: ¿EL SINDICALISMO ARGENTINO ESTÁ PREPARADO PARA UN MUNDO GLOBAL? Héctor Palomino .. 5