1,334 research outputs found

    On Semi Alpha Syndetic Sets

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    In this peper we present new class of syndetic sets called Semi- -Synditic sets and study their basic properties in topological groups Keywords:- Semi- -open set, Semi- -closed set, Semi- -compact and Semi- -syndetic set

    Synthesis, Characterization and Antibacterial Evaluations of the Schiff Base 2-(1-(2-(Piperazin-1-yl)ethylimino)ethyl)Phenol and its Complexes of Mn(II), Ni(II) and Zn(II)

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    Schiff base 2-(1-(2-(piperazin-1-yl)ethylimino)ethyl)phenol and its complexes of Mn(II), Ni(II) and Zn(II) were synthesized and characterized by molar conductance, FTIR, NMR, UV-Visible and elemental analysis. The complexes showed 1:1 metal to ligand (M:L) ratio according to the result obtained from Job’s method analysis. Elemental analysis and IR spectral data are in good agreement with the proposed structure of the ligand and the complexes. Both the ligand and its complexes were screened for in-vitro antibacterial activity against two gram negative (Escherichia coli and Klebsella) and two gram positive (Staphylococcus aureus and Streptococcus pyrogenes) bacterial strains. The result of antibacterial activity showed that both the ligand and its complexes have activity more than the referenced drug and that the complexes are more active than free ligand.Keywords: Antibacterial studies, Characterization, Continuous variation, Synthesi

    PENINGKATAN PENGETAHUAN MASYARAKAT TENTANG PERAN GIZI SEIMBANG DENGAN KOMPOSISI ISI PIRINGKU PADA MASA PANDEMI COVID-19

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    In Sorong city, West Papua Province shows that the results of laboratory tests for covid-19 in November 2020, there were an additional 25 positive Covid-19 people, 19 people from Sorong City, and six people from Manokwari Regency. Total positive cases covid-19 in West Papua increased to 4,640 people or 17,3% of the total number of people who had been examined, as many as 26,813. Balanced nutrition is a good step for people in Klamono Village, Klawana Village, to find out how to improve the immune system and prevent contracting Covid-19. This community service aims to increase public knowledge about the role of balanced nutrition during the Covid-19 pandemic. The subjects of this community service are adults and the elderly, as many as 30 people aged between 20 - 51 years. The methods used in this community service are lecture, observation, and documentation. The results of this community service showed that the percentage of previous participants 'knowledge was 55,32%. Furthermore, the post-test results showed that the participants' knowledge had increased to 100%. They understood balanced nutrition with the composition of the contents of my plate as a form of prevention of Covid-19—positive response from participants in the discussion. Nutrition balanced with the contents of my plate is a substitute for four healthy five perfect, which is very easy to understand and apply by participants in their daily life. Consuming balanced nutritious food and drinks with the composition of the contents of my plate will help maintain the body and improve the body's immune system during the Covid-19 pandemic. ... Di Kota Sorong, Provinsi Papua Barat menunjukkan bahwa hasil pemeriksaan laboratorium covid-19 pada bulan november tahun 2020, terdapat penambahan 25 orang positif covid-19 , yang berasal dari Kota Sorong 19 orang, dan Kabupaten Manokwari 6 orang, total kasus positif covid-19 di Papua Barat bertambah menjadi 4.640 orang atau 17,3% dari total jumlah orang yang telah diperiksa sebanyak 26.813 orang. Gizi seimbang merupakan langkah baik bagi masyarakat di Kelurahan Klamono, Kampung Klawana untuk mengetahui cara meningkatkan sistim imun dan pencegahan tertular covid-19. Pengabmas ini bertujuan untuk mengetahui peningkatan pengetahuan masyarakat tentang peran gizi seimbang pada masa pandemi covid-19. Subjek pada pengabmas ini adalah orang dewasa dan lansia, sebanyak 30 orang, berusia antara 20 - 51 tahun. Metode yang digunakan pada pengabmas ini adalah metode ceramah menggunakan power point, dan diberikan pre–post test kepada peserta, serta dokumentasi. Hasil pengabmas ini menunjukkan bahwa presentase pengetahuan peserta sebelumnya sebesar 55,32% dan hasil post test menunjukkan bahwa pengetahuan peserta meningkat menjadi 100% setelah diberikan ceramah, peserta telah memahami gizi seimbang dengan komposisi isi piringku. Respon positif dari peserta dengan adanya pertanyaan dan diskusi. Gizi seimbang dengan isi piringku merupakan pengganti 4 sehat lima sempurna, yang sangat mudah dipahami dan diterapkan oleh peserta dalam kehidupan sehari-hari. Mengonsumsi makanan dan minuman bergizi seimbang dengan komposisi isi piringku akan membantu menjaga tubuh dan meningkatkan sistim imunitas tubuh pada masa pandemi covid-19.

    On the order and type of entire functions defined by multiple Dirichlet series

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    In this paper, we shall obtain some relations between the orders and types of entire functions represented by multiple Dirichlet series. By taking asymptotic behavior in their coefficients .The results has been given in the form of theorems

    Antidiabetic effect of fermented Pennisetum glaucum (millet) supplement in alloxan induced hyperglycemic wistar rats

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    Diabetes mellitus is a debilitating disease that is characterized clinically by hyperglycemia due to chronic and/or relative insulin insufficiency. The disease is associated with disturbance in lipid and protein metabolism. Pennisetum glaucum (PG) has been recommended for several therapeutic purposes as it has been shown to have high amount of magnesium which helps to increase the levels of adiponectin hormone but the hypoglycemic effect of millet as a supplement is yet to be fully elucidated. Therefore this research was designed to determine the effect of Pennisetum glaucum supplement on blood glucose level and serum lipid profile. Diabetes mellitus was induced by single intraperitoneal (i.p) injection of alloxan dissolved in 0.1ml fresh cold citrate buffer pH 4.5 at a dose of 150 mg/kg body weight, after which the rats were randomly divided into 5 groups. Group 1 normoglycemic, Group 2 Diabetic untreated, Group 3 Diabetic treated with 1 mg/kg of Glibenclamide (GB). Group 4 Diabetic treated with 33%w/v P.G. supplement, Group 5 Diabetic treated with 66% P.G. supplement. When compared with the diabetic control, the study revealed a significant decrease (p>0.05) in blood glucose level at both 33%w/v and 66% w/v P.G. supplementation. It also showed that P.G. at both 33% and 66% supplement was able to lower Triglycerides and LDL serum levels as well increase HDL serum levels although not statistically significant, but significantly restored HDL/Cholesterol and Triglycerides/HDL ratios to normal physiological range. Pennisetum glaucum supplementation showed high hypoglycemic effect and also hypolipidemic property in alloxan induced hyperglycemic wistar rats.Keywords: Pennisetum glaucum, hypolipidemia, hyperglycemi

    (R1513) The Dynamical Study of Variable Mass Test Particle in Nonlinear Sense of Restricted 3-body Problem with Heterogeneous Primaries

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    The main idea of this paper is to study the non-linear stability property of the motion of the test particle which is moving under the influence of heterogeneous primaries having N-layers with different densities as well as varying its mass according to Jeans law. The system is also perturbed by the small perturbations in Coriolis as well as centrifugal forces. We evaluate the equations of motion of the test particle under the influence of the above said perturbations. From this system of equations of motion, we reveal analytically the locations of stationary points as well as the non-linear stability

    Vertical Motion of the Variable Infinitesimal Mass In the Circular Sitnikov Problem

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    The circular case of Sitnikov problem is studied here when the infinitesimal body varies its mass according to Jeans law and it is moving along the z-axis which is perpendicular to the orbital plane of the two equal spherical primaries. The two primaries are moving in xy-plane on the same circular path. These two primaries are imposing the Newtonian forces on the third variable mass body but not influenced by it. Stability of equilibrium points is examined followed by the derived equations of motion. The time-series solutions of the equation of motion are performed by using the Lindstedt-Poincaré method which is used to remove the secular term. We have numerically performed the time-series which shows that variation parameters have great impact on it

    Effects of Senna occidentalis leaf supplement on blood glucose level, liver enzymes and total protein in alloxan-induced diabetic wistar rats

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    Diabetes mellitus is one of the most common non communicable diseases around the world and is responsible for many deaths resulting from some of its serious complications. Senna occidentalis Linn. is extensively being used in folklore medicine to cure and/or manage many disease conditions, although its adequate validation as therapeutic (specifically anti-diabetic and hepatoprotective) effects has not been established. The aim of this study is to determine the effects of Senna occidentalis leaf supplement on blood glucose level, liver enzymes and total protein in alloxan-induced diabetic wistar rats. Diabetes was induced by single intraperitoneal injection of alloxan (150 mg/kg). Thereafter the rats were fed with Senna occidentalis leaf supplement at doses of 12.5%, 25% and 50% .Also Glibenclamide was used as a standard drug (2 mg/kg ) as positive control and diabetic control received distilled water as negative control. Blood glucose levels were measured at day 0, 4, 8, 12 and 16. The liver enzymes and total protein were also determined using the serum and histopathological studies of the pancreas and liver were conducted. Quantitative phytochemical screening revealed that the supplement has high amount of phytoconstitutuents like total phenols, flavonoids, tannins, saponins and alkaloids, which have a percentage composition of 20%, 10.80%, 15%, 0.55% and 7.20%, respectively. Blood glucose levels of all animals treated with the supplement were reduced significantly (p<0.05) by about 82.13%, 88.36 and 81.78% respectively when compared with that of the untreated diabetic control group. There was also an increase in the total protein (p< 0.05) to 90.98 ± 6.02, 73.72 ± 3.02 and 92.23 ± 4.01, respectively in comparison to that of the untreated diabetic group having 69.04 ± 3.59; and hepatotoxicity due to the observed increase in the activities of all the liver enzymes as well as hepatocellular necrosis, sinusoidal congestion and hemorrhage as revealed in the histopathological studies of the liver. This study shows that S. occidentalis leaf supplement has potent hypoglycemic effect due to its high content of active principles that possess strong and potent insulinomimetic and β-cell regenerating potential as depicted by the histopathological studies of the pancreatic tissue, even though, some cytotoxic agents like the cytotoxic saponins may be present in the supplement which is capable of causing damage to both pancreas and liver . These findings prove its use in traditional medicine for the treatment of diabetes but with caution due to its probable potential to induce hepatotoxicity.Keywords: Antidiabetic, Hepatoprotective, Hepatotoxicity, Phytoconstitutuents, Insulinomimetic, Senna occidentali

    Effects of fermented soya bean supplements on lipid profile and oxidative stress biomarkers in high fat diet-induced Type 2 diabetes mellitus in rabbits

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    Background: High fat diets are known to increase body weight and fat mass, induce alterations in carbohydrate and lipid metabolism, leading to insulin resistance and diabetes mellitus. The aim of this study was to evaluate the effects of fermented soya bean supplements on lipid profile and oxidative stress biomarkers in high fat diet-induced type 2 diabetes mellitus in rabbits.Methods: Twenty rabbits weighing between 1kg – 2kg were used for the study. Type 2 diabetes mellitus was induced by feeding the animals with high fat diet (2% cholesterol, 20% groundnut meal, 10% groundnut oil) for eight weeks. Rabbits having fasting blood glucose levels of 7.2 mmol/L (130mg/dL) and above after the induction period were selected for the study. The animals were grouped into four groups of five rabbits each: Group 1 (diabetic control), received distilled water ad libitum for six weeks; groups 2, 3 and 4 (diabetic rabbits) were fed with 12.5%, 25% and 50% fermented soya bean supplements respectively for six weeks. Thereafter, the rabbits were sacrificed and blood samples obtained for analyses. Data were analysed using analysis of variance (ANOVA).Results: There was a significant decrease (p ≤ 0.05) in triglyceride and LDL concentrations in the group fed 50% fermented soya bean supplements and a significant increase in HDL levels (p ≤ 0.05) in all the fermented soya bean supplemented groups when compared with the diabetic control group. The result also showed a significant decrease (p ≤ 0.05) in malondialdehyde concentration in all the treated groups when compared with the control group. Superoxide dismutase was significantly decreased in the group fed 12.5% and 25% fermented soya bean supplements while catalase was significantly decreased in the group fed 12.5% fermented soya bean supplement when compared with the control group.Conclusion: Fermented soya bean supplements decreased lipid profile and improved antioxidant activities in diabetic rabbits and may prove beneficial in the management of hyperlipidaemia and oxidative stress in diabetic patients.Keywords: Diabetes mellitus, fermented soya beans, high fat diet, hyperlipidaemia, lipid profile, oxidative stress biomarker
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