Of Mice and Ice in the Late Pliocene of North America

Between 2.5 to 1.8 million years ago changes in arctic climate and in meadow mouse dispersal routes correlate with part of the history of uplift and glacial erosion of the Chugach and Saint Elias mountains in Alaska and adjacent Canada. Earlier meadow mice dispersing from Asia to central North America followed a southward coastal route between these mountains and the Pacific Ocean, appearing first in the United States Pacific Northwest. Two and a half million years ago, accelerated uplift of the Chugach and Saint Elias mountains milked Pacific westerly winds, enlarging the ice fields in these mountains so that they then flowed to the sea. This blocked the coastal dispersal for 600,000 years, when no new immigrant meadow mice appeared in the conterminous United States. The uplift also restrained westerly winds that crossed Canada, permitting moister air from the subtropical Atlantic and from an unfrozen Arctic Ocean to produce significant continental glaciation, centered in eastern Canada. By 2.0 million years ago, glacial erosion had lowered these mountains again, letting relatively dry Pacific westerlies extend across Canada, reducing the encroachment of moist Atlantic and arctic air, and ending continental glaciation to the east. The simultaneous reduction of glacial activity in the cordillera allowed meadow mice to renew southward dispersal. Additionally, the lowered mountains remained a rain shadow, causing grassland in the Great Plains of Canada. Thus a new dispersal route to the United States was opened for grazing meadow mice and for the first time their earliest records were in the Great Plains. Loss of the continental ice sheet and an unfrozen Arctic Ocean facilitated the northward spread of warm and moist air from the North Atlantic subtropical high; it flowed northward up the eastern front of the Rocky Mountains in the United States and, mingling with the dry westerlies, northeastward across Canada to northernmost Greenland, where trees then grew. About 1.8 million years ago the Great Plains of the United States were subtropical savannah and remained so until the beginning of the Ice Age 850,000 years ago.

Using Simulations as a Starting Point for Constructing Meaningful Learning Games

For many school administrators and decision makers, the term “video games” holds numerous cultural associations which make their adoption in the education space challenging. Additionally, the term is so broad that it can sometimes be difficult to communicate explicitly a desire to build learning experiences that go beyond the Drill and Kill edutainment titles that currently dominate most people’s perceptions of educational games. By contrast, the term “simulations” is often well respected among educators, particularly in the natural sciences. With “simulation” already being a full genre of video games, it would seem natural that researchers are beginning to explore the overlaps between simulation games and pedagogical goals that go beyond those found in Drill and Kill games. In this chapter, we survey some of the relevant research concerning both simulations and video games and outline practical pathways through which we can leverage the interest and frameworks designed for simulation construction to facilitate the introduction of video game concepts and experiences into the classroom environment. In particular, we report on the use of Starlogo TNG, a graphical programming environment in which kids themselves can create simulation-based video games, for deepening children’s understanding of scientific concepts

Unveiling key factors shaping energy storage strategies for sustainable energy communities

Producción CientíficaThis research delves into a case study of a photovoltaic (PV) energy community, leveraging empirical data to explore the integration of renewable energy sources and storage solutions. By evaluating energy generation and consumption patterns within real-world energy communities (a nominal generation capacity of 33 kWn) in Gipuzkoa, Spain, from May 2022 to May 2023, this study comprehensively examines operational dynamics and performance metrics. This study highlights the critical role of energy consumption patterns in facilitating the integration of renewable energy sources and underscores the importance of proactive strategies to manage demand fluctuations effectively. Against the backdrop of rising energy costs and environmental concerns, renewable energies and storage solutions emerge as compelling alternatives, offering financial feasibility and environmental benefits within energy communities. This study emphasizes the necessity of research and development efforts to develop efficient energy storage technologies and the importance of economic incentives and collaborative initiatives to drive investments in renewable energy infrastructure. The analyzed results provide valuable insights into operational dynamics and performance metrics, further advancing our understanding of their transformative potential in achieving a sustainable energy future. Specifically, our study suggests that storage capacity should ideally support an average annual capacity of 23%, with fluctuations observed where this capacity may double or reduce to a minimum in certain months. Given the current market conditions, our findings indicate the necessity of significant public subsidies, amounting to no less than 67%, to facilitate the installation of storage infrastructure, especially in cases where initial investments are not covered by the energy community

Innervation patterns of sea otter (Enhydra lutris) mystacial follicle-sinus complexes

Sea otters (Enhydra lutris) are the most recent group of mammals to return to the sea, and may exemplify divergent somatosensory tactile systems among mammals. Therefore, we quantified the mystacial vibrissal array of sea otters and histologically processed follicle-sinus complexes (F - SCs) to test the hypotheses that the number of myelinated axons per F - SC is greater than that found for terrestrial mammalian vibrissae and that their organization and microstructure converge with those of pinniped vibrissae. A mean of 120.5 vibrissae were arranged rostrally on a broad, blunt muzzle in 7–8 rows and 9–13 columns. The F-SCs of sea otters are tripartite in their organization and similar in microstructure to pinnipeds rather than terrestrial species. Each F-SC was innervated by a mean 1339 ± 408.3 axons. Innervation to the entire mystacial vibrissal array was estimated at 161,313 axons. Our data support the hypothesis that the disproportionate expansion of the coronal gyrus in somatosensory cortex of sea otters is related to the high innervation investment of the mystacial vibrissal array, and that quantifying innervation investment is a good proxy for tactile sensitivity. We predict that the tactile performance of sea otter mystacial vibrissae is comparable to that of harbor seals, sea lions and walruses

Exceptional Record of Mid-Pleistocene Vertebrates Helps Differentiate Climatic from Anthropogenic Ecosystem Perturbations

Mid-Pleistocene vertebrates in North America are scarce but important for recognizing the ecological effects of climatic change in the absence of humans. We report on a uniquely rich mid-Pleistocene vertebrate sequence from Porcupine Cave, Colorado, which records at least 127 species and the earliest appearances of 30 mammals and birds. By analyzing \u3e20,000 mammal fossils in relation to modern species and independent climatic proxies, we determined how mammal communities reacted to presumed glacial-interglacial transitions between 1,000,000 and 600,000 years ago. We conclude that climatic warming primarily affected mammals of lower trophic and size categories, in contrast to documented human impacts on higher trophic and size categories historically. Despite changes in species composition and minor changes in small-mammal species richness evident at times of climatic change, overall structural stability of mammal communities persisted \u3e600,000 years before human impacts

My IoT Puzzle: Debugging IF-THEN Rules Through the Jigsaw Metaphor

End users can nowadays define applications in the format of IF-THEN rules to personalize their IoT devices and online services. Along with the possibility to compose such applications, however, comes the need to debug them, e.g., to avoid unpredictable and dangerous behaviors. In this context, different questions are still unexplored: which visual languages are more appropriate for debugging IF-THEN rules? Which information do end users need to understand, identify, and correct errors? To answer these questions, we first conducted a literature analysis by reviewing previous works on end-user debugging, with the aim of extracting design guidelines. Then, we developed My IoT Puzzle, a tool to compose and debug IF-THEN rules based on the Jigsaw metaphor. My IoT Puzzle interactively assists users in the debugging process with different real-time feedback, and it allows the resolution of conflicts by providing textual and graphical explanations. An exploratory study with 6 participants preliminary confirms the effectiveness of our approach, showing that the usage of the Jigsaw metaphor, along with real-time feedback and explanations, helps users understand and fix conflicts among IF-THEN rules

Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families

Glutathione S-transferases (GSTs) form a superfamily defined by their ability to catalyze the conjugation of glutathione with electrophilic substrates. These enzymes are proposed to play a critical role in protection of cellular components from damage mediated by reactive metabolites. Twenty-two cytosolic GSTs, grouped into seven families, are recognized in mice. This complexity hinders the assignment of function to a subset or family of these genes. We report generation of a mouse line in which the locus encoding three GST gene families is deleted. This includes the four Gstt genes spanning 65 kb on chromosome 10 and the seven Gstm genes found on a 150 kb segment of DNA chromosome 3. In addition, we delete two Gstp genes on chromosome 19 as well as a third related gene located 15 kb telomeric to Gstp1 and Gstp2, which we identify as a potential new member of this gene family. We show that, despite the loss of up to 75% of total GST activity in some tissues from these animals, the mice are healthy and fertile, with normal life expectancy. The normal development and health of these animals make them an appropriate model for defining the role of these families in redox homeostasis and metabolism of drugs and environmental pollutants

End-User development goes to school: Collaborative learning with makerspaces in subject areas

Norwegian K-12 curriculum reform for 2020 aims to integrate programming in different subject areas, especially math, natural sciences, arts and crafts, and music. There are challenges and opportunities associated with this scenario. A challenge is that students need to learn two topics simultaneously, and an opportunity is that teachers can adopt computer science skills gradually by building on their domain expertise and the notion of different levels of modification since most teachers are not yet fluent in computer science. We present an exploratory case study to show that end-user development (EUD) is a possible solution for the Norwegian situation. The case study demonstrates evidence of collaborative learning with EUD in a makerspace in an advanced placement science classroom for a mixture of gifted underachievers and high-achievers.acceptedVersio

A mobile-based solution for supporting end-users in the composition of services

The final publication is available at Springer via http://dx.doi.org/10.1007/s11042-016-3910-4Currently, technologies and applications evolve to create eco-systems made up of a myriad of heterogeneous and distributed services that are accessible anytime and anywhere. Even though these services can be used individually, it is their coordinated and combined usage what provide an added value to end-users. In addition, user¿s wide adoption of mobile devices for daily activities have fostered a shift in the role played by end-users towards Internet data and services. However, existing solutions to service composition are not targeted to ordinary end-users. More easy-to-use tools have to be offered to end-users to make sure that they are successfully accepted and used by them. To this end, the work presented in this paper supports end-users in the creation of service compositions by using mobile devices. 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Pliocene and Pleistocene geologic and climatic evolution in the San Luis Valley of south-central Colorado

Sediments of the Alamosa Formation spanning the upper part of the Gauss and most of the Matuyama Chrons were recovered by coring in the high (2300 m) San Luis Valley of south-central Colorado. The study site is located at the northern end of the Rio Grande rift. Lithologic changes in the core sediments provide evidence of events leading to integration of the San Luis drainage basin into the Rio Grande. The section, which includes the Huckleberry Ridge Ash (2.02 Ma) and spans the entire Matuyama Chron, contains pollen, and invertebrate and vertebrate fossils. Stable isotope analyses of inorganic and biogenic carbonate taken over most of the core indicate substantially warmer temperatures than occur today in the San Luis Valley. At the end of the Olduvai Subchron, summer precipitation decreased, summer pan evaporation increased, and temperatures increased slightly compared to the earlier climate represented in the core. By the end of the Jaramillo Subchron, however, cold/wet and warm/dry cycles become evident and continue into the cold/wet regime associated with the deep-sea oxygen-isotope Stage 22 glaciation previously determined from outcrops at the same locality. Correspondence between the Hansen Bluff climatic record and the deep-sea oxygen-isotope record (oxygen-isotope stages from about 110-18) is apparent, indicating that climate at Hansen Bluff was responding to global climatic changes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29956/1/0000316.pd