Rushing to Overpay: The REIT Premium Revisited

We explore the questions of whether and why Real Estate Investment Trusts (REITs) pay more for real estate than non-REIT buyers, consequently breaking the law of one price. We develop a model where REITs optimally pay more for property because (1) they are able, due to capital access advantages and, (2) are occasionally compelled, due to regulatory time constraints on the deployment of capital. We show that the typically large (20 to 60 percent) and statistically significant (p-values less than 0.01) REIT-buyer premiums found in standard empirical hedonic pricing models are biased due to unobserved explanatory variables. Using a repeat-transaction methodology that controls for unobserved independent variables, we find the REIT-buyer premium to be about 5 percent. Furthermore, we show that REITs¿ ability (as measured by access to capital markets) and regulator compulsion (as measured by capital deployment deadlines) are related to the price premium.Real Estate Investment Trusts (REITs), commercial properties, hedonic price analysis, repeat transactions, market efficiency, law of one price, price premium

Time to focus on outcome assessment tools for childhood vasculitis

Childhood systemic vasculitides are a group of rare diseases with multi-organ involvement and potentially devastating consequences. After establishment of new classification criteria (Ankara consensus conference in 2008), it is now time to establish measures for proper definition of activity and damage in childhood primary vasculitis. By comparison to adult vasculitis, there is no consensus for indices of activity and damage assessment in childhood vasculitis. Assessment of disease activity is likely to become a major area of interest in pediatric rheumatology in the near future. After defining the classification criteria for primary systemic childhood vasculitis, the next step was to perform a validation study using the original Birmingham vasculitis activity score as well as the disease extent index to measure disease activity in childhood vasculitis. Presently, there are efforts in place to develop a pediatric vasculitis activity score. This paper reviews the current understanding about the assessment tools (i.e., clinical features, laboratory tests, radiologic assessments, etc.) widely used for evaluation of the disease activity and damage status of the children with vasculitis. © 2011 Demirkaya et al; licensee BioMed Central Ltd

Synthesis of novel multifunctional carbazole-based molecules and their thermal, electrochemical and optical properties

Two novel carbazole-based compounds 7a and 7b were synthesised as potential candidates for application in organic electronics. The materials were fully characterised by NMR spectroscopy, mass spectrometry, FTIR, thermogravimetric analysis, differential scanning calorimetry, cyclic voltammetry, and absorption and emission spectroscopy. Compounds 7a and 7b, both of which were amorphous solids, were stable up to 291 °C and 307 °C, respectively. Compounds 7a and 7b show three distinctive absorption bands: high and mid energy bands due to locally excited (LE) transitions and low energy bands due to intramolecular charge transfer (ICT) transitions. In dichloromethane solutions compounds 7a and 7b gave emission maxima at 561 nm and 482 nm with quantum efficiencies of 5.4% and 97.4% ± 10%, respectively. At positive potential, compounds 7a and 7b gave two different oxidation peaks, respectively: quasi-reversible at 0.55 V and 0.71 V, and reversible at 0.84 V and 0.99 V. At negative potentials, compounds 7a and 7b only exhibited an irreversible reduction peak at −1.86 V and −1.93 V, respectively

Travmatik yaşantısı olan yetişkinlerde travma sonrası stres bozukluğu ve travma sonrası gelişim: boylamsal bir çalışma

TÜBİTAK SOBAG15.01.201

Yetişkinlerde travmatik olay yaşama yaygınlığı, travma sonrası stres bozukluğu ve travma sonrası gelişim'in değerlendirilmesi

TÜBİTAK SOBAG Proje15.08.2009The aim of this study was to examine the prevalence of various traumatic life events and Post Traumatic Stress Disorder (PTSD) among adults living in Erzincan, Ankara and Kocaeli provinces in Turkey. The relationship of socio-demographic characteristics, type of traumatic event and its characteristics and personality traits with PTSD and Post Traumatic Growth (PTG) were also evaluated. The study was conducted with a sample of 1253 adults, from a stratified cluster sample provided by the Turkish Statistical Institute. The research instrument containing a sociodemographic information form, the Post Traumatic Diagnostic Scale, Post Traumatic Growth Inventory, Basic Personality Traits Inventory and Brief Symptom Checklist was administered to participants in their homes by trained interviewers. The results showed that 84%(n= 1055) of participants reported experiencing at least one traumatic event. Six hundred and seventy five (64%) of these were female and 389 (36%) were male. Compared to females, males reported accidents, physical violence, war experiences, being imprisoned and torture events more often. The rates of PTSD in the whole sample was 9.9%(n=124). Females had a significantly higher rate of PTSD (77.4%) as compared to males (%22.6). Furthermore, the prevalence of PTSD varied for different types of traumatic events. PTSD rates following human made/deliberate traumatic events (39.6%) and death/illness (24.9%) were higher than the rates following accidents (14.8%) and natural disasters (13.3%). After controlling for the effects of sociodemographic variables, low extraversion, high agreeableness and high neuroticism significantly predicted the severity of post traumatic stress reactions. From among the event related variables, the impact of the traumatic event and the degree of functional impairment due to the event, experiencing death/illness and human made/deliberate events rather than accidents amd natural disasters 15 and experiencing more traumatic events appeared as significant predictors of post traumatic stress reactions. For PTG, after controlling for the effects of sociodemographic variables, agreeableness, openness to experience and conscientiousness appeared as significant predictors. From among the event related variables, the impact of the traumatic event, the severity of post traumatic stress reactions, and experiencing human made/deliberate, death/illness and natural disasters rather than accidents were related to PTG. The findings of the study are discussed in the scope of the existing literature and suggestions for the planning of mental health services and trauma training programs are offered

Functional status, patient satisfaction and quality of life in patients with arthroscopic partial meniscectomy

Objectives: This study aims to investigate the effects of clinical and demographic variables on functional status, patient satisfaction and quality of life following arthroscopic partial meniscectomy. Patients and methods: Between January 2001 and December 2010, 98 patients (44 males, 54 females; mean age 52.1±12.5 years; range 18 to 88 years) who underwent arthroscopic partial meniscectomy in our clinic and were eligible for the study. Demographic and clinical data of patients and surgical characteristics were recorded. Preoperative activity levels of patients were measured. Severity of activity pain and patient satisfaction following surgery were evaluated using Visual Analog Scale (VAS). Functional status was evaluated by Lysholm knee score and WOMAC (Osteoarthritis Index Western Ontario and McMaster Universities), while quality of life was evaluated by Short Form-36 (SF-36). Results: Postoperative mean time from surgery was 62.5±26.1 (8-120) months, VAS score at rest was 1.7±2.6 (0-10), VAS activity score was 3.4±3.3 (0-10) and VAS patient satisfaction score was 7.0±3.0 (0-10). It was found that 68 of the patients (69.4%) were evaluated themselves as excellent or better than preoperative period with a mean Lysholm knee score of 73.8±17.4 (24-95). Significant influences of body mass index and preoperative symptom duration on evaluation parameters were not detected. Male gender, less than five years after surgery, less intraoperative joint degeneration and moderate to severe activity level before the onset of symptoms had a positive influence on the severity of pain, patient satisfaction and functional status. Conclusion: Our study provided critical data for optimal patient selection during the preoperative period to predict which patients may have better results in the mid-term follow-up after arthroscopic partial meniscectomy

Integrated usage of geophysical prospection techniques in Höyük (tepe, tell)-type archaeological settlements

The integrated use of geophysical methods has developed rapidly in the last fifteen years in archaeological prospection (Brizzolari et al., 1992; Gaffney et al., 2004; Drahor, 2006; Casana et al., 2008). The combined application of different geophysical techniques supplies useful information about buried archaeological contexts, particularly höyük(tell, tepe)-type archaeological settlements. The aim of such studies is to help archaeologists conduct fast, effective and economical excavations b..

Influence of the gut microbiome on IgE and non-IgE-mediated food allergies

Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- MAY 26-30, 2018 -- Munich, GERMANYWOS: 000441690400204Background: The prevalence of food allergy (FA) in children has been increasing in last decade. Recent studies show changes in gut microbiome with FA. However, whether gut microbiome may differ between IgE and non‐IgE‐mediated FA is not defined. The aim of this study is to examine the intestinal microbiome composition in infants with IgE and non‐IgE‐mediated FA and healthy infants. Method: Infants younger than 1‐year‐old, breastfed and diagnosed with FA by a physician were included in the study. DNA was isolated from stool samples of infants with non‐IgE‐mediated FA (n = 25) and IgE‐mediated FA (n = 11) and healthy infants (n = 7). Whole genome shotgun sequencing was applied to identify the composition of microbial DNA (an average depth of 3.1 ± 0.8 million paired end reads and 0.9 ± 0.2 gigabase pairs). Results: There were compositional differences among 3 different groups. Shannon index was significantly higher in IgE‐mediated FA compared to non‐IgE‐mediated FA group (Kruskal‐Wallis test, P = 0.034). Even though β‐diversity was similar, the Sparse Partial Least Square Discriminant Analysis (sPLS‐DA) demonstrated that there were taxa‐level differences among three groups. In species level, Veillonella parvula was in a significantly higher density in healthy infants compared to IgE and non‐IgE‐mediated FA groups. Rahnella aquatilis and Lactobacillus salivarius were significantly lower and Treponema succinifaciens significantly higher in IgE‐mediated FA group compared to other groups. Additionally, Prevotella sp. oral taxon 299 was significantly lower in non‐IgE‐mediated FA group compared to others. Prevotella sp oral taxon 299 was related to mucus in stool whereas urticaria related species were Olsenall uli, Bactreoides thetaiotaomicron, Klebsiella variiocola, Rahnella aquatilis, Treponema succinfaciens, Ethanoligenens harbinenese. Conclusion: Analysis of microbiome differences in FA patients may aid in the understanding of the disease process. The present data suggest that there are compositional variations mostly in species‐ level among infants with FA and healthy ones. Our results suggest that the gut microbiome has a stronger relationship to IgE‐mediated than non‐IgE‐mediated FA. Further functional analysis of the microbiome may help better understand the changes seen in the gut microbiome in FAs and improve our knowledge in the disease etiopathology.European Academy of Allergy and Clinical Immunolog

Over restrictive elimination of foods in children with foodallergy

Background. Previous studies demonstrated critical deficits in diagnosis and management of childhood foodallergy (FA), and recent developments in FA research support adopting a proactive approach in FA management.Our objective was to describe FA knowledge and management patterns of pediatricians.Method. We applied a 24-item survey to 170 general pediatricians, pediatric allergists and pediatricgastroenterologists practicing in Turkey.Results. Some IgE-mediated symptoms of FA such as cough, urticaria, wheezing and anaphylaxis were falselyrecognized as symptoms of non-IgE-mediated FA by 30%, 29%, 25% and 19% of the participants, respectively.By contrast, 50% of the participants falsely recognized bloody stool, a finding of IgE-mediated FA. Mostfrequently and least frequently used diagnostic tools were specific IgE (30.5%) and oral food challenge test(1.7%), respectively. Maternal diet restrictions and infant diet restrictions were advised by 82% and 82%,respectively. Percentages of physicians eliminating only 1 food were 21%, 19%; 2 foods were 15%, 11%; 3 foodswere 7%, 8%; 4-5 foods were 8%, 11%; 5 to 10 foods were 21%, 26%; and >10 foods were 28%, 25% from thematernal and infant diet, respectively. Cow’s milk, cheese, butter, yoghurt, baked milk products and hen’s eggwere the most commonly restricted items.Conclusion. Overall, FA knowledge of pediatricians was fair. Pediatricians utilize an overly restrictive approachwhen advising diet eliminations in FA. Recent developments favor a more proactive approach to induce immunetolerance and need to be encouraged in pediatric clinical practice. Future educational efforts should focus onemphasizing the deleterious effects of injudicious and extensive eliminations