Survey Paper on Online Software Performance Prediction

Now a days Performance is very important non-functional requirement for almost all software system. In survey study we are going to learn how performance prediction is possible before the development of that particular software. For this task we have to implement one analytical model which is going to be used for evaluating the performance of software with some specific parameter like response time, throughput etc

CONCEPT OF IMPROVING STRENGTH IN AYURVEDA W.S.R IMUNITY

Ayurveda is the science of human health and disease. It deals with comfort, discomfort, physiological and pathological aspect of life. The word immunity means the strength of protecting from infectious diseases. The immune system evolved as defense system to protect body from invading pathological microorganisms and malignant diseases. Strong immunity is the key for maintaining stability in health with the changing season. Vyadhikshamatva is described in Ayurveda and this concept is considered equivalent to immunity. Normal condition of kapha, Bala and ojas are also similar to immunity. Vyadhikshamatva literally means resistance (ksamatva) against disease (vyadhi). Physical and mental resistance to disease is of enormous significance for all living being, it regulates both prevention against and rapid recovery from diseases. Ojas is final and excellence of the product dhatu and vyadhiksamatva depends on it. Innate immunity may be correlated to sahajabala and kalajabala may be correlated to acquired immunity. Here is a review of Ayurvedic texts regarding immunity and concept of Vyadhiksamatva which depends on normal dosa, equilibrium state of dhatu, normal agnibala and ojas etc

A Critical Review On Blepharitis And Its Ayurvedic Approach

Blepharitis is a common eye condition characterized by inflammation of the eyelid  margins resulting in inflamed, irritated, itchy, reddened and oedematous eyelids. A number of diseases and conditions can lead to blepharitis. It can be caused by the oil glands at the base of the eyelashes becoming clogged due to  bacterial infection, allergies or other conditions. The severity and course can vary. Blepharitis is a long-standing chronic granulomatous inflammation of lid margins.American Optometric Association has concluded that if blepharitis left untreated it can cause more serious conditions such as scarring or injury to the eye tissue or also lead to dry eye syndrome.Also,some cases of blepharitis may require more complex treatment plans and even with the successful treatment recurrence may occur4.Blepharitis can be correlated with the sign and symptoms of Praklinna vartma which is breifly explained in vartmagat netravyadhis in Sushrut samhita.According to the Tridosh siddhant of Ayurveda blepharitis is a kaphaj vyadhi. Ayurvedic preparations for local application like Triphala rasakriya varti,Apamarga rasakriya varti,Vanshmool raskriya varti,Palash pushp raskriya varti are explained by Sushrutacharya in the treatment of praklinna vartma5

A Novel Method for Filtering Unwanted Messages from OSN user Walls

One principal issue in today On-line Social Systems (OSNs) is to give clients the capacity to control the messages posted all alone private space to keep away from that undesirable substance is shown. Up to now OSNs give little backing to this prerequisite. To fill the hole, in this paper, we propose a framework permitting OSN clients to have an immediate control on the messages posted on their dividers. This is accomplished through an adaptable guideline based framework, that permits clients to alter the separating criteria to be connected to their dividers, and a Machine Learning based delicate classifier naturally naming messages in backing of substance based separating

Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites

Protozoan infections are a serious global health problem1, 2. Natural killer (NK) cells and cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic granule contents—granzyme (Gzm) proteases and the pore-forming perforin (PFN)—into the infected cell3. However, these cytotoxic molecules do not kill intracellular parasites. CD8+ CTLs protect against parasite infections in mice primarily by secreting interferon (IFN)-γ4, 5, 6, 7, 8, 9, 10. However, human, but not rodent, cytotoxic granules contain the antimicrobial peptide granulysin (GNLY), which selectively destroys cholesterol-poor microbial membranes11, 12, 13, 14, and GNLY, PFN and Gzms rapidly kill intracellular bacteria15. Here we show that GNLY delivers Gzms into three protozoan parasites (Trypanosoma cruzi, Toxoplasma gondii and Leishmania major), in which the Gzms generate superoxide and inactivate oxidative defense enzymes to kill the parasite. PFN delivers GNLY and Gzms into infected cells, and GNLY then delivers Gzms to the intracellular parasites. Killer cell–mediated parasite death, which we term 'microbe-programmed cell death' or 'microptosis', is caspase independent but resembles mammalian apoptosis, causing mitochondrial swelling, transmembrane potential dissipation, membrane blebbing, phosphatidylserine exposure, DNA damage and chromatin condensation. GNLY-transgenic mice are protected against infection by T. cruzi and T. gondii, and survive infections that are lethal to wild-type mice. Thus, GNLY-, PFN- and Gzm-mediated elimination of intracellular protozoan parasites is an unappreciated immune defense mechanism

PENGARUH SUBSTITUSI TEPUNG KROKOT (Portulaca oleracea L) DALAM RANSUM TERHADAP BERAT SEBELUM PEMOTONGAN, BERAT SETELAH PEMOTONGAN, KARKAS, NON KARKAS SERTA LEMAK ABDOMINAL AYAM BROILER

The study was carried out in Balai Besar Pelatihan Peternakan Noelbaki, Kupangfor 6 weeks: December8–January18, 2017. The study aimed at evaluating the effect and best level of including Portulaca oleraceaL in the diet on final, slaughter, carcass, non-carcass and abdominal fatof broiler. There were 100 grower broilers used in the study. Completely randomized design 4 treatments with 5 replicates (5 broiler of each) procedure applied. The treatments were formulated as:KR0 (commercial diet without Portulaca oleracea L meal); KR5;95% commercial diet + 5% Portulaca oleracea L meal;KR10: 90% commercial diet + 10% Portulaca oleracea L  meal; and KR15 : 85% commercial diet + 15% Portulaca oleracea L meal. The variables evaluated were: pre and post slaughter, carcass and non-carcass, and abdominal fat weights of broiler. Statistical analysis showed that effect of treatment significant and post slaughter weights significant (P<0.05), but not significant (P>0.05) on pre slaughter, carcass, non-carcass weight and abdominal fat weights of the broilers. The conclusion is that including Portulaca oleracea L meal substituting commercial diet up to 15% performed the similar results in both carcass and non-carcass weight of broiler. ABSTRAK  Penelitian ini telah dilaksanakan di Balai Besar Pelatihan Peternakan Noelbaki, Kupang selama 6 minggu terhitung sejak tanggal 8 Desember – 18 Januari 2017. Tujuan penelitian  adalah untuk mengetahui pengaruh dan level terbaik penggunaan tepung krokot dalam ransum terhadap berat hidup akhir, berat potong, berat karkas, non karkas serta lemak abdominal ayam broiler. Materi yang digunakan adalah 100 ekor ternak ayam broiler fase grower. Penelitian ini menggunakan Rancangan Acak Lengkap Berblok (RALB) dengan empat perlakuan dan lima ulangan. Perlakuan yang dicobakan adalah :KR0: Ransum komersial tanpa penambahan tepung krokot (kontrol),  KR5 : 95% ransum komersial + 5% tepung krokot, KR10: 90% ransum komersial + 10% tepung krokot dan KR15 : 85% ransum komersial + 15% tepung krokot. Variabel yang diukur adalah berat sebelum pemotongan, berat setelah pemotongan, berat karkas, berat non karkas, serta berat lemak abdominal ayam broiler. Hasil analisis statistik menunjukkan bahwa perlakuan berpengaruh terhadap (P<0,05) berat setelah pemotongan, Namun memberikan pengaruh tidak nyata (P>0,05) terhadap berat sebelum pemotongan, berat karkas, berat non karkas dan berat lemak abdominal ayam broiler. Berdasarkan hasil yang diperoleh maka disimpulkan bahwa substitusi krokot sampai dengan level 15% dalam ransum ayam broiler masih dalam batasan yang normal dan tidak memberikan pengaruh negatif terhadap karkasdan non karkas ayam broiler.&nbsp

Biofuel Expansion, Fertilizer Use, and GHG Emissions: Unintended Consequences of Mitigation Policies

Increased biofuel production has been associated with direct and indirect land-use change, changes in land management practices, and increased application of fertilizers and pesticides. This has resulted in negative environmental consequences in terms of increased carbon emissions, water quality, pollution, and sediment loads, which may offset the pursued environmental benefits of biofuels. This study analyzes two distinct policies aimed at mitigating the negative environmental impacts of increased agricultural production due to biofuel expansion. The first scenario is a fertilizer tax, which results in an increase in the US nitrogen fertilizer price, and the second is a policy-driven reversion of US cropland into forestland (afforestation). Results show that taxing fertilizer reduces US production of nitrogen-intensive crops, but this is partially offset by higher fertilizer use in other countries responding to higher crop prices. In the afforestation scenario, crop production shifts from high-yielding land in the United States to low-yielding land in the rest of the world. Important policy implications are that domestic policy changes implemented by a large producer like the United States can have fairly significant impacts on the aggregate world commodity markets. Also, the law of unintended consequences results in an inadvertent increase in global greenhouse gas emissions

Researching Market and Supply-Chain Opportunities for Local Foods Systems: Setting Priorities and Identifying Linkages

There is an increasing array of land-grant, nonprofit, and other academic programs intended to support the development of food system enterprises and programs. However, research to track consumers\u27 evolving preferences and behaviors within these systems and to measure the intended policy outcomes of any public investments in these systems is lagging. This research commentary represents a compilation of opinions and insights from those who are interested in exploring research priorities for economic, marketing, and supply-chain aspects of local food systems. The priorities that emerge are framed in the following way: (1) opportunities for increased and more targeted research to help identify gaps in the literature; (2) areas where current localized research projects could be leveraged and scaled up to the national level; and (3) innovative projects and partnerships that are evolving to bridge both knowledge and systems gaps

Foley catheterisation versus oral misoprostol for induction of labour in hypertensive women in India (INFORM): a multicentre, open-label, randomised controlled trial

Background Between 62 000 and 77 000 women die annually from pre-eclampsia and eclampsia. Prompt delivery, preferably by the vaginal route, is vital for good maternal and neonatal outcomes. Two low-cost interventions—low-dose oral misoprostol tablets and transcervical Foley catheterisation—are already used in low-resource settings. We aimed to compare the relative risks and benefits of these interventions. Methods We undertook this multicentre, open-label, randomised controlled trial in two public hospitals in Nagpur, India. Women (aged ≥18 years) who were at 20 weeks' gestation or later with a live fetus and required delivery as a result of pre-eclampsia or hypertension were randomly assigned (1:1), via computer-generated block randomisation (block sizes of four, six, and eight) with concealment by use of opaque, sequentially numbered, sealed envelopes, to receive labour induction with either oral misoprostol 25 μg every 2 h (maximum of 12 doses) or a transcervical Foley catheter (silicone, size 18 F with 30 mL balloon). Randomisation was stratified by study centre. The catheter remained in place until active labour started, the catheter fell out, or 12 h had elapsed. If the catheter did not fall out within 12 h, induction continued with artificial membrane rupture and oxytocin, administered through a micro-drip gravity infusion set. Fetal monitoring was by intermittent auscultation. The primary outcome was vaginal birth within 24 h. Due to the nature of the interventions, masking of participants, study investigators, and care providers to group allocation was not possible. We analysed by intention to treat. This trial is registered with ClinicalTrials.gov, number NCT01801410. Findings Between Dec 20, 2013, and June 29, 2015, we randomly assigned 602 women to induction with misoprostol (n=302) or the Foley catheter (n=300; intention-to-treat population). Vaginal birth within 24 h was more common in women in the misoprostol group than in the Foley catheter group (172 [57·0%] vs 141 [47·0%] women; absolute risk difference 10·0%, 95% CI 2·0–17·9; p=0·0136). Rates of uterine hyperstimulation were low in both the misoprostol and Foley catheter groups (two [0·7%] vs one [0·3%] cases; absolute risk difference 0·3%, 95% CI −0·8 to 1·5; p=0·566) and neonatal deaths did not differ significantly between groups (six [2·0%] vs three [1·0%] neonatal deaths; 1·0, −1·04 to 2·97; p=0·322). 17 serious adverse events (3%) were reported during the study: one case of intrapartum convulsion and one case of disseminated intravascular coagulation (both in the Foley group); ten perinatal deaths, including two stillbirths (both in the Foley catheter group) and eight neonatal deaths (n=5 in the misoprostol group and n=3 in the Foley catheter group); and five of neonatal morbidity, comprising birth asphyxia (n=3), septicaemia (n=1), and neonatal convulsion (n=1). Interpretation Oral misoprostol was more effective than transcervical Foley catheterisation for induction of labour in women with pre-eclampsia or hypertension. Future studies are required to assess whether oxytocin augmentation following misoprostol can be replaced by regular doses of oral misoprostol tablets